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Items: 1 to 20 of 34

1.

Atherosclerosis

Atherosclerosis is a disease in which plaque builds up inside your arteries. Plaque is a sticky substance made up of fat, cholesterol, calcium, and other substances found in the blood. Over time, plaque hardens and narrows your arteries. That limits the flow of oxygen-rich blood to your body. Atherosclerosis can lead to serious problems, including. -Coronary artery disease. These arteries supply blood to your heart. When they are blocked, you can suffer angina or a heart attack. -Carotid artery disease. These arteries supply blood to your brain. When they are blocked you can suffer a stroke. -Peripheral arterial disease. These arteries are in your arms, legs and pelvis. When they are blocked, you can suffer from numbness, pain and sometimes infections. Atherosclerosis usually doesn't cause symptoms until it severely narrows or totally blocks an artery. Many people don't know they have it until they have a medical emergency. A physical exam, imaging, and other diagnostic tests can tell if you have it. Medicines can slow the progress of plaque buildup. Your doctor may also recommend procedures such as angioplasty to open the arteries, or surgery on the coronary or carotid arteries. Lifestyle changes can also help. These include following a healthy diet, getting regular exercise, maintaining a healthy weight, quitting smoking, and managing stress. . NIH: National Heart, Lung, and Blood Institute.  [from MedlinePlus]

MedGen UID:
13948
Concept ID:
C0004153
Disease or Syndrome
2.

Prolonged

MedGen UID:
615082
Concept ID:
C0439590
Temporal Concept
3.

Luminal

MedGen UID:
147015
Concept ID:
C0699493
Organic Chemical; Pharmacologic Substance
4.

Hyperplasia

An abnormal increase in the number of cells in an organ or tissue. [from NCI]

MedGen UID:
43784
Concept ID:
C0020507
Pathologic Function
5.

Hypertrophy

Cell size enlargement due to the increase in the amount of cytoplasm and its constituent organelles. The cells are larger but otherwise the appearance is unchanged. [from NCI_CDISC]

MedGen UID:
5703
Concept ID:
C0020564
Pathologic Function
6.

Hypercholesterolaemia

An increased concentration of cholesterol in the blood. [from HPO]

MedGen UID:
5687
Concept ID:
C0020443
Disease or Syndrome
7.

Bromodeoxyuridine

A nucleoside that substitutes for thymidine in DNA and thus acts as an antimetabolite. It causes breaks in chromosomes and has been proposed as an antiviral and antineoplastic agent. It has been given orphan drug status for use in the treatment of primary brain tumors. [from MeSH]

MedGen UID:
2358
Concept ID:
C0006233
Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance
8.

Pressure

MedGen UID:
632176
Concept ID:
C0460139
Finding
9.

Primary hypercholesterolemia

MedGen UID:
575264
Concept ID:
C0342879
Disease or Syndrome
10.

Plaque

In medicine, a small, abnormal patch of tissue on a body part or an organ. Plaques may also be a build-up of substances from a fluid, such as cholesterol in the blood vessels. [from NCI]

MedGen UID:
452424
Concept ID:
C0332461
Body Substance; Finding
11.

Hypercholesterolemia

A laboratory test result indicating an increased amount of cholesterol in the blood. [from NCI]

MedGen UID:
312004
Concept ID:
C1522133
Finding; Laboratory or Test Result
12.

Stress

Everyone feels stressed from time to time. Not all stress is bad. All animals have a stress response, and it can be life-saving. But chronic stress can cause both physical and mental harm. There are at least three different types of stress:. -Routine stress related to the pressures of work, family, and other daily responsibilities. -Stress brought about by a sudden negative change, such as losing a job, divorce, or illness. -Traumatic stress, which happens when you are in danger of being seriously hurt or killed. Examples include a major accident, war, assault, or a natural disaster. This type of stress can cause post-traumatic stress disorder (PTSD). Different people may feel stress in different ways. Some people experience digestive symptoms. Others may have headaches, sleeplessness, depressed mood, anger, and irritability. People under chronic stress get more frequent and severe viral infections, such as the flu or common cold. Vaccines, such as the flu shot, are less effective for them. Some people cope with stress more effectively than others. It's important to know your limits when it comes to stress, so you can avoid more serious health effects. NIH: National Institute of Mental Health.  [from MedlinePlus]

MedGen UID:
20971
Concept ID:
C0038435
Finding
13.

Dental plaque

film that attaches to teeth, often causing dental caries and gingivitis; composed of mucins, secreted from salivary glands, and microorganisms. [from CRISP]

MedGen UID:
8301
Concept ID:
C0011389
Disease or Syndrome
14.

NSC-38297

MedGen UID:
163893
Concept ID:
C0878530
Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance
15.

Pathological Conditions, Anatomical

An abnormal structural condition of the human body, usually macroscopic, that is common to a variety of different diseases. [from MeSH]

MedGen UID:
155708
Concept ID:
C0752135
Pathologic Function
16.

Course of illness

Stages or progression of physical or mental disorders. Compare PROGNOSIS. [from PSY]

MedGen UID:
116631
Concept ID:
C0242656
Pathologic Function
17.

vessel (polysaccharide)

MedGen UID:
56099
Concept ID:
C0148346
Carbohydrate; Organic Chemical; Pharmacologic Substance
18.

Unspecified encephalopathy

Encephalopathy is a term that means brain disease, damage, or malfunction. In general, encephalopathy is manifested by an altered mental state. [from HPO]

MedGen UID:
39314
Concept ID:
C0085584
Disease or Syndrome
19.

Vascular disorder

The vascular system is the body's network of blood vessels. It includes the arteries, veins and capillaries that carry blood to and from the heart. Problems of the vascular system are common and can be serious. Arteries can become thick and stiff, a problem called atherosclerosis. Blood clots can clog vessels and block blood flow to the heart or brain. Weakened blood vessels can burst, causing bleeding inside the body. . You are more likely to have vascular disease as you get older. Other factors that make vascular disease more likely include. - Family history of vascular or heart diseases. - Pregnancy. - Illness or injury . - Long periods of sitting or standing still. - Any condition that affects the heart and blood vessels, such as diabetes or high cholesterol . - Smoking . - Obesity . Losing weight, eating healthy foods, being active and not smoking can help vascular disease. Other treatments include medicines and surgery.  [from MedlinePlus]

MedGen UID:
22621
Concept ID:
C0042373
Disease or Syndrome
20.

Uridine

A nucleoside consisting of uracil and D-ribose and a component of RNA. Uridine has been studied as a rescue agent to reduce the toxicities associated with 5-fluorouracil (5-FU), thereby allowing the administration of higher doses of 5-FU in chemotherapy regimens. (NCI04) [from NCI]

MedGen UID:
22572
Concept ID:
C0041984
Biologically Active Substance; Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance
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