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Sulfone

MedGen UID:
21395
Concept ID:
C0038761
Organic Chemical; Pharmacologic Substance
Synonyms: Sulfones
SNOMED CT: Sulfone (363549008)
 

Definition

Any of substance containing a sulfonyl functional group attached to two carbon atoms with antibiotic activity. Tthe general structural formula is R-S(=O)(=O)-R'. [from NCI]

Recent clinical studies

Etiology

Nurulain SM, Shafiullah M, Yasin J, Adem A, Kaabi JA, Tariq S, Adeghate E, Ojha S
Arh Hig Rada Toksikol 2016 Jun 1;67(2):126-35. doi: 10.1515/aiht-2016-67-2776. PMID: 27331300
Murph MM, Jiang GW, Altman MK, Jia W, Nguyen DT, Fambrough JM, Hardman WJ, Nguyen HT, Tran SK, Alshamrani AA, Madan D, Zhang J, Prestwich GD
Bioorg Med Chem 2015 Sep 1;23(17):5999-6013. Epub 2015 Jul 2 doi: 10.1016/j.bmc.2015.06.054. PMID: 26190462Free PMC Article
Liéby-Muller F, Heudré Le Baliner Q, Grisoni S, Fournier E, Guilbaud N, Marion F
Bioorg Med Chem Lett 2015;25(10):2078-81. Epub 2015 Apr 3 doi: 10.1016/j.bmcl.2015.03.081. PMID: 25872984
Zou W, Qin H, Shi W, Sun S, Zhao C
Langmuir 2014 Nov 18;30(45):13622-30. Epub 2014 Nov 7 doi: 10.1021/la502343c. PMID: 25347292
del Castillo T, Marales-Sanfrutos J, Santoyo-González F, Magez S, Lopez-Jaramillo FJ, Garcia-Salcedo JA
ChemMedChem 2014 Feb;9(2):383-9. Epub 2013 Dec 13 doi: 10.1002/cmdc.201300385. PMID: 24339407

Diagnosis

Staniszewska M, Bondaryk M, Ochal Z
Bioorg Med Chem 2015 Jan 15;23(2):314-21. Epub 2014 Dec 4 doi: 10.1016/j.bmc.2014.11.038. PMID: 25515956
González-Hernández I, Ruiz-Olmedo MI, Cárdenas G, Jung-Cook H
Biomed Chromatogr 2012 Feb;26(2):267-72. Epub 2011 Jul 1 doi: 10.1002/bmc.1659. PMID: 21721022
Stępnik M, Ferlińska M, Smok-Pieniążek A, Gradecka-Meesters D, Arkusz J, Stańczyk M
Toxicol In Vitro 2011 Aug;25(5):1075-84. Epub 2011 Apr 15 doi: 10.1016/j.tiv.2011.04.011. PMID: 21515355
Takeuchi A, Yamamoto S, Narai R, Nishida M, Yashiki M, Sakui N, Namera A
Biomed Chromatogr 2010 May;24(5):465-71. doi: 10.1002/bmc.1313. PMID: 19688817
Böttiger Y
Eur J Clin Pharmacol 2006 Aug;62(8):621-5. Epub 2006 Jun 22 doi: 10.1007/s00228-006-0156-5. PMID: 16791583

Therapy

Murph MM, Jiang GW, Altman MK, Jia W, Nguyen DT, Fambrough JM, Hardman WJ, Nguyen HT, Tran SK, Alshamrani AA, Madan D, Zhang J, Prestwich GD
Bioorg Med Chem 2015 Sep 1;23(17):5999-6013. Epub 2015 Jul 2 doi: 10.1016/j.bmc.2015.06.054. PMID: 26190462Free PMC Article
del Castillo T, Marales-Sanfrutos J, Santoyo-González F, Magez S, Lopez-Jaramillo FJ, Garcia-Salcedo JA
ChemMedChem 2014 Feb;9(2):383-9. Epub 2013 Dec 13 doi: 10.1002/cmdc.201300385. PMID: 24339407
González-Hernández I, Ruiz-Olmedo MI, Cárdenas G, Jung-Cook H
Biomed Chromatogr 2012 Feb;26(2):267-72. Epub 2011 Jul 1 doi: 10.1002/bmc.1659. PMID: 21721022
Stępnik M, Ferlińska M, Smok-Pieniążek A, Gradecka-Meesters D, Arkusz J, Stańczyk M
Med Oncol 2012 Jun;29(2):1161-72. Epub 2011 Apr 27 doi: 10.1007/s12032-011-9920-1. PMID: 21523454
Adas G, Arikan S, Kemik O, Oner A, Sahip N, Karatepe O
World J Gastroenterol 2009 Jan 7;15(1):112-6. PMID: 19115476Free PMC Article

Prognosis

Seng KY, Fan L, Lee HS, Yong WP, Goh BC, Lee LS
Ther Drug Monit 2011 Dec;33(6):719-29. doi: 10.1097/FTD.0b013e318237a9e9. PMID: 22105589
Yanagida Y, Watanabe M, Takeba Y, Kumai T, Matsumoto N, Hayashi M, Suzuki S, Kinoshita Y, Kobayashi S
Biol Pharm Bull 2009 Aug;32(8):1422-6. PMID: 19652384
Abidi MH, Kozlowski JR, Ibrahim RB, Peres E
Hematol Oncol 2006 Sep;24(3):164-5. doi: 10.1002/hon.780. PMID: 16639690
Huang L, Beard CB, Creasman J, Levy D, Duchin JS, Lee S, Pieniazek N, Carter JL, del Rio C, Rimland D, Navin TR
J Infect Dis 2000 Oct;182(4):1192-8. Epub 2000 Sep 8 doi: 10.1086/315824. PMID: 10979917
Barnard GF, Scharf MJ, Dagher RK
Am J Gastroenterol 1994 Nov;89(11):2057-9. PMID: 7942736

Clinical prediction guides

Romero A, Ramos E, Ares I, Castellano V, Martínez M, Martínez-Larrañaga MR, Anadón A, Martínez MA
Toxicol Lett 2016 Jun 11;252:42-9. Epub 2016 Apr 8 doi: 10.1016/j.toxlet.2016.04.005. PMID: 27067106
Seo KA, Lee SJ, Kim KB, Bae SK, Liu KH, Kim DH, Shin JG
Xenobiotica 2012 Mar;42(3):278-84. Epub 2011 Oct 24 doi: 10.3109/00498254.2011.622416. PMID: 22022918
Sauter A, Soulsby H, Hormann K, Naim R
Anticancer Res 2010 Feb;30(2):339-43. PMID: 20332437
Adas G, Arikan S, Kemik O, Oner A, Sahip N, Karatepe O
World J Gastroenterol 2009 Jan 7;15(1):112-6. PMID: 19115476Free PMC Article
Sauter A, Matharu R, Braun T, Schultz J, Sadick H, Hormann K, Naim R
Arch Med Res 2007 May;38(4):367-71. Epub 2007 Mar 6 doi: 10.1016/j.arcmed.2006.11.005. PMID: 17416281

Recent systematic reviews

Gramec Skledar D, Peterlin Mašič L
Environ Toxicol Pharmacol 2016 Oct;47:182-199. Epub 2016 Sep 22 doi: 10.1016/j.etap.2016.09.014. PMID: 27771500
Kędzierska K, Sindrewicz K, Smektała T, Wiśniewska M, Masiuk M, Staniszewska E, Sporniak-Tutak K, Gołembiewska E, Ciechanowski K
Postepy Hig Med Dosw (Online) 2016 Mar 16;70:210-8. doi: 10.5604/17322693.1197372. PMID: 27117096
Rochester JR, Bolden AL
Environ Health Perspect 2015 Jul;123(7):643-50. Epub 2015 Mar 16 doi: 10.1289/ehp.1408989. PMID: 25775505Free PMC Article
de Vos P, Lazarjani HA, Poncelet D, Faas MM
Adv Drug Deliv Rev 2014 Apr;67-68:15-34. Epub 2013 Nov 22 doi: 10.1016/j.addr.2013.11.005. PMID: 24270009
Tsui T, Boon H, Boecker A, Kachan N, Krahn M
BMC Complement Altern Med 2012 Oct 30;12:198. doi: 10.1186/1472-6882-12-198. PMID: 23107559Free PMC Article

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