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Items: 10

1.

Aminoglycosides

Glycosylated compounds in which there is an amino substituent on the glycoside. Some of them are clinically important ANTIBIOTICS. [from MeSH]

MedGen UID:
257
Concept ID:
C0002556
Organic Chemical; Pharmacologic Substance
2.

catechol

A chemical originally isolated from a type of mimosa tree. Catechol is used as an astringent, an antiseptic, and in photography, electroplating, and making other chemicals. It can also be man-made. [from NCI_NCI-GLOSS]

MedGen UID:
27059
Concept ID:
C0054858
Organic Chemical; Pharmacologic Substance
3.

Streptomycin

An antibiotic produced by the soil actinomycete Streptomyces griseus. It acts by inhibiting the initiation and elongation processes during protein synthesis. [from MeSH]

MedGen UID:
20967
Concept ID:
C0038425
Antibiotic; Organic Chemical
4.

Starvation

Lengthy and continuous deprivation of food. (Stedman, 25th ed) [from MeSH]

MedGen UID:
20944
Concept ID:
C0038187
Finding
5.

Kanamycin

Antibiotic complex produced by Streptomyces kanamyceticus from Japanese soil. Comprises 3 components: kanamycin A, the major component, and kanamycins B and C, the minor components. [from MeSH]

MedGen UID:
7193
Concept ID:
C0022487
Antibiotic; Organic Chemical
6.

Amikacin

A broad-spectrum semi-synthetic aminoglycoside antibiotic, derived from kanamycin with antimicrobial property. Amikacin irreversibly binds to the bacterial 30S ribosomal subunit, specifically locking 16S rRNA and S12 protein within the 30S subunit. This leads to interference with translational initiation complex and misreading of mRNA, thereby hampering protein synthesis and resulting in bactericidal effect. This agent is usually used in short-term treatment of serious infections due to susceptible strains of Gram-negative bacteria. [from NCI]

MedGen UID:
1863
Concept ID:
C0002499
Antibiotic; Organic Chemical
7.

Lipopeptides

Compounds consisting of a short peptide chain conjugated with an acyl chain. [from MeSH]

MedGen UID:
378385
Concept ID:
C2266975
Amino Acid, Peptide, or Protein; Pharmacologic Substance
8.

Antimicrobial substance

Any substance or process that kills germs (bacteria, viruses, and other microorganisms that can cause infection and disease). [from NCI_NCI-GLOSS]

MedGen UID:
209727
Concept ID:
C1136254
Pharmacologic Substance
9.

Sequence Deletion

Deletion of sequences of nucleic acids from the genetic material of an individual. [from MeSH]

MedGen UID:
102460
Concept ID:
C0162773
Cell or Molecular Dysfunction
10.

Anti-Infective Agents

A pharmacological agent that can kill or prevent the reproduction of infectious organisms. [from NCI]

MedGen UID:
324
Concept ID:
C0003204
Pharmacologic Substance
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