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Leiomyosarcoma

MedGen UID:
9711
Concept ID:
C0023269
Neoplastic Process
Synonyms: Leiomyosarcomas
SNOMED CT: LMS - Leiomyosarcoma (51549004); Leiomyosarcoma, no subtype (51549004); Leiomyosarcoma (443719001); Leiomyosarcoma (51549004)
 
HPO: HP:0100243
Orphanet: ORPHA64720

Definition

A smooth muscle connective tissue tumor, which is rare type of cancer that is a malignant neoplasm of smooth muscle. When such a neoplasm is benign, it is called a leiomyoma. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLeiomyosarcoma
Follow this link to review classifications for Leiomyosarcoma in Orphanet.

Recent clinical studies

Etiology

Skorstad M, Kent A, Lieng M
Acta Obstet Gynecol Scand 2016 Nov;95(11):1228-1234. doi: 10.1111/aogs.13008. PMID: 27564388
Alkhalili E, Greenbaum A, Langsfeld M, Marek J, Rana MA, Glew R, Nir I
Ann Vasc Surg 2016 May;33:245-51. Epub 2016 Jan 21 doi: 10.1016/j.avsg.2015.10.016. PMID: 26802297
Rodriguez AM, Asoglu MR, Sak ME, Tan A, Borahay MA, Kilic GS
Eur J Obstet Gynecol Reprod Biol 2016 Feb;197:31-5. Epub 2015 Nov 28 doi: 10.1016/j.ejogrb.2015.11.009. PMID: 26699101
Zheng SD, Bui K, Chiappori A, Bepler G, Bui MM
Pathol Oncol Res 2016 Jul;22(3):477-82. Epub 2015 Nov 26 doi: 10.1007/s12253-015-0021-x. PMID: 26612755
Kim HJ, Cho YJ, Kim SH, Rha SY, Ahn JB, Yang WI, Lee YH, Suh JS, Roh JK, Kim KS, Choi YD, Shin KH, Kim HS
Int J Clin Oncol 2015 Dec;20(6):1226-32. Epub 2015 Jun 28 doi: 10.1007/s10147-015-0847-y. PMID: 26123311

Diagnosis

Gohrbandt AE, Hansen T, Ell C, Heinrich SS, Lang H
BMC Surg 2016 Sep 1;16(1):60. doi: 10.1186/s12893-016-0174-x. PMID: 27580598Free PMC Article
Skorstad M, Kent A, Lieng M
Acta Obstet Gynecol Scand 2016 Nov;95(11):1228-1234. doi: 10.1111/aogs.13008. PMID: 27564388
Rodriguez AM, Asoglu MR, Sak ME, Tan A, Borahay MA, Kilic GS
Eur J Obstet Gynecol Reprod Biol 2016 Feb;197:31-5. Epub 2015 Nov 28 doi: 10.1016/j.ejogrb.2015.11.009. PMID: 26699101
Lv Y, Pang X, Zhang Q, Jia D
Int J Clin Exp Pathol 2015 Nov 1;8(11):15412-6. PMID: 26823904Free PMC Article
Bozzini G, Albersen M, Romero Otero J, Margreiter M, Garcia Cruz E, Mueller A, Gratzke C, Serefoglu EC, Martinez Salamanca JI, Verze P
Int J Surg 2015 Dec;24(Pt A):81-4. Epub 2015 Nov 11 doi: 10.1016/j.ijsu.2015.11.012. PMID: 26578108

Therapy

Morita I, Isoda R, Hirabayashi Y, Naomoto Y
Asian Cardiovasc Thorac Ann 2016 Oct;24(8):801-804. Epub 2016 Jul 26 doi: 10.1177/0218492316659975. PMID: 27461101
Cananzi FC, Mussi C, Bordoni MG, Marrari A, De Sanctis R, Colombo P, Quagliuolo V
J Surg Oncol 2016 Jul;114(1):44-9. Epub 2016 Apr 6 doi: 10.1002/jso.24244. PMID: 27062161
Yakupoglu A, Ulus S, Cantasdemir M
Vasc Endovascular Surg 2016 Apr;50(3):164-7. Epub 2016 Mar 21 doi: 10.1177/1538574416637445. PMID: 27000390
Babichev Y, Kabaroff L, Datti A, Uehling D, Isaac M, Al-Awar R, Prakesch M, Sun RX, Boutros PC, Venier R, Dickson BC, Gladdy RA
J Transl Med 2016 Mar 8;14:67. doi: 10.1186/s12967-016-0814-z. PMID: 26952093Free PMC Article
Pautier P, Floquet A, Chevreau C, Penel N, Guillemet C, Delcambre C, Cupissol D, Selle F, Isambert N, Piperno-Neumann S, Thyss A, Bertucci F, Bompas E, Alexandre J, Collard O, Lavau-Denes S, Soulié P, Toulmonde M, Le Cesne A, Lacas B, Duffaud F; French Sarcoma Group.
Lancet Oncol 2015 Apr;16(4):457-64. Epub 2015 Mar 18 doi: 10.1016/S1470-2045(15)70070-7. PMID: 25795402

Prognosis

Onishi T, Yanagihara Y, Kikugawa T, Miura N, Noda T, Kakuda T, Kitazawa R, Tanji N
World J Surg Oncol 2016 Jul 2;14(1):176. doi: 10.1186/s12957-016-0936-z. PMID: 27368929Free PMC Article
Yakupoglu A, Ulus S, Cantasdemir M
Vasc Endovascular Surg 2016 Apr;50(3):164-7. Epub 2016 Mar 21 doi: 10.1177/1538574416637445. PMID: 27000390
Rodriguez AM, Asoglu MR, Sak ME, Tan A, Borahay MA, Kilic GS
Eur J Obstet Gynecol Reprod Biol 2016 Feb;197:31-5. Epub 2015 Nov 28 doi: 10.1016/j.ejogrb.2015.11.009. PMID: 26699101
Zheng SD, Bui K, Chiappori A, Bepler G, Bui MM
Pathol Oncol Res 2016 Jul;22(3):477-82. Epub 2015 Nov 26 doi: 10.1007/s12253-015-0021-x. PMID: 26612755
Kim HJ, Cho YJ, Kim SH, Rha SY, Ahn JB, Yang WI, Lee YH, Suh JS, Roh JK, Kim KS, Choi YD, Shin KH, Kim HS
Int J Clin Oncol 2015 Dec;20(6):1226-32. Epub 2015 Jun 28 doi: 10.1007/s10147-015-0847-y. PMID: 26123311

Clinical prediction guides

Cananzi FC, Mussi C, Bordoni MG, Marrari A, De Sanctis R, Colombo P, Quagliuolo V
J Surg Oncol 2016 Jul;114(1):44-9. Epub 2016 Apr 6 doi: 10.1002/jso.24244. PMID: 27062161
Yakupoglu A, Ulus S, Cantasdemir M
Vasc Endovascular Surg 2016 Apr;50(3):164-7. Epub 2016 Mar 21 doi: 10.1177/1538574416637445. PMID: 27000390
Roland CL, Boland GM, Demicco EG, Lusby K, Ingram D, May CD, Kivlin CM, Watson K, Al Sannaa GA, Wang WL, Ravi V, Pollock RE, Lev D, Cormier JN, Hunt KK, Feig BW, Lazar AJ, Torres KE
JAMA Surg 2016 Apr;151(4):347-54. doi: 10.1001/jamasurg.2015.4205. PMID: 26629783Free PMC Article
Zheng SD, Bui K, Chiappori A, Bepler G, Bui MM
Pathol Oncol Res 2016 Jul;22(3):477-82. Epub 2015 Nov 26 doi: 10.1007/s12253-015-0021-x. PMID: 26612755
Kim BR, Lee JH, Cho E, Kim DC, Park YM, Ha DH, Choi S
Clin Imaging 2015 Nov-Dec;39(6):1105-7. Epub 2015 Jul 17 doi: 10.1016/j.clinimag.2015.06.014. PMID: 26278012

Recent systematic reviews

Wang JG, Cui L, Jiang T, Li YJ, Wei ZM
Asian Cardiovasc Thorac Ann 2015 Jun;23(5):623-30. Epub 2015 Mar 3 doi: 10.1177/0218492315574197. PMID: 25740020
Bogani G, Cliby WA, Aletti GD
Gynecol Oncol 2015 Apr;137(1):167-72. Epub 2014 Nov 20 doi: 10.1016/j.ygyno.2014.11.011. PMID: 25462199
Pritts EA, Parker WH, Brown J, Olive DL
J Minim Invasive Gynecol 2015 Jan;22(1):26-33. Epub 2014 Sep 3 doi: 10.1016/j.jmig.2014.08.781. PMID: 25193444
Gupta AA, Yao X, Verma S, Mackay H, Hopkins L; Sarcoma Disease Site Group and the Gynecology Cancer Disease Site Group.
Clin Oncol (R Coll Radiol) 2013 Jun;25(6):346-55. Epub 2013 Jan 5 doi: 10.1016/j.clon.2012.11.008. PMID: 23295078
Eppsteiner RW, DeYoung BR, Milhem MM, Pagedar NA
Arch Otolaryngol Head Neck Surg 2011 Sep;137(9):921-4. doi: 10.1001/archoto.2011.147. PMID: 21930982Free PMC Article

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