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Developmental disorder

MedGen UID:
3367
Concept ID:
C0008073
Mental or Behavioral Dysfunction
Synonyms: Child Development Disorder; Child Development Disorders; Development Disorder, Child; Development Disorders, Child; Developmental Disabilities; Developmental Disability; Disabilities, Developmental; Disability, Developmental
SNOMED CT: Developmental disorder (5294002)
 

Definition

Developmental disabilities are severe, long-term problems. They may be physical, such as blindness. They may affect mental ability, such as learning disorders. Or the problem can be both physical and mental, such as Down syndrome. The problems are usually life-long, and can affect everyday living. . There are many causes of developmental disabilities, including. -Genetic or chromosome abnormalities. These cause conditions such as Down syndrome and Rett syndrome. -Prenatal exposure to substances. Drinking alcohol when pregnant can cause fetal alcohol spectrum disorders. -Certain viral infections during pregnancy. -Preterm birth. Often there is no cure, but treatment can help the symptoms. Treatments include physical, speech, and occupational therapy. Special education classes and psychological counseling can also help. NIH: National Institute of Child Health and Human Development.  [from MedlinePlus]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDevelopmental disorder

Recent clinical studies

Etiology

Nylander L, Fernell E, Gillberg C
Nord J Psychiatry 2016 Oct;70(7):508-13. Epub 2016 Apr 29 doi: 10.1080/08039488.2016.1175504. PMID: 27125391
Waris P, Tani P, Lindberg N, Lipsanen J, Kettunen K, Kaltiala-Heino R, Saarimaa LK, Reinvall O, Voutilainen A, Hokkanen L
Appl Neuropsychol Child 2016 Oct-Dec;5(4):303-10. Epub 2016 Mar 25 doi: 10.1080/21622965.2015.1064001. PMID: 27015370
Fujii C, Okada A, Akagi T, Shigeyasu Y, Shimauchi A, Hosogi M, Munemori E, Ocho K, Morishima T
Pediatr Int 2016 Jan;58(1):8-13. doi: 10.1111/ped.12790. PMID: 26270796
Genereaux D, van Karnebeek CD, Birch PH
Disabil Health J 2015 Oct;8(4):646-51. Epub 2015 Apr 11 doi: 10.1016/j.dhjo.2015.03.011. PMID: 25991418
Fujiwara T, Kasahara M, Tsujii H, Okuyama M
Child Abuse Negl 2014 Aug;38(8):1283-9. Epub 2014 May 9 doi: 10.1016/j.chiabu.2014.04.007. PMID: 24813254

Diagnosis

Nylander L, Fernell E, Gillberg C
Nord J Psychiatry 2016 Oct;70(7):508-13. Epub 2016 Apr 29 doi: 10.1080/08039488.2016.1175504. PMID: 27125391
Waris P, Tani P, Lindberg N, Lipsanen J, Kettunen K, Kaltiala-Heino R, Saarimaa LK, Reinvall O, Voutilainen A, Hokkanen L
Appl Neuropsychol Child 2016 Oct-Dec;5(4):303-10. Epub 2016 Mar 25 doi: 10.1080/21622965.2015.1064001. PMID: 27015370
Fujii C, Okada A, Akagi T, Shigeyasu Y, Shimauchi A, Hosogi M, Munemori E, Ocho K, Morishima T
Pediatr Int 2016 Jan;58(1):8-13. doi: 10.1111/ped.12790. PMID: 26270796
McMorris CA, Perry A
Autism 2015 Apr;19(3):272-80. Epub 2014 Jan 24 doi: 10.1177/1362361313518123. PMID: 24463433
Fujiwara T, Kasahara M, Tsujii H, Okuyama M
Child Abuse Negl 2014 Aug;38(8):1283-9. Epub 2014 May 9 doi: 10.1016/j.chiabu.2014.04.007. PMID: 24813254

Therapy

Geier DA, Kern JK, King PG, Sykes LK, Geier MR
Biol Trace Elem Res 2015 Feb;163(1-2):28-38. Epub 2014 Nov 11 doi: 10.1007/s12011-014-0169-3. PMID: 25382662Free PMC Article
Kanemura H, Sano F, Ohyama T, Sugita K, Aihara M
Eur J Paediatr Neurol 2014 Jul;18(4):482-8. Epub 2014 Mar 26 doi: 10.1016/j.ejpn.2014.03.007. PMID: 24703761
Arun P, Chavan BS, Bhargava R, Sharma A, Kaur J
Indian J Med Res 2013;138:89-98. PMID: 24056561Free PMC Article
Wake R, Miyaoka T, Inagaki T, Furuya M, Ieda M, Liaury K, Kishi K, Horiguchi J
J Child Adolesc Psychopharmacol 2013 Jun;23(5):329-36. doi: 10.1089/cap.2012.0108. PMID: 23782127
de Bildt A, Mulder EJ, Scheers T, Minderaa RB, Tobi H
Pediatrics 2006 Dec;118(6):e1860-6. doi: 10.1542/peds.2005-3101. PMID: 17142506

Prognosis

Munir KM
Curr Opin Psychiatry 2016 Mar;29(2):95-102. doi: 10.1097/YCO.0000000000000236. PMID: 26779862Free PMC Article
Fujii C, Okada A, Akagi T, Shigeyasu Y, Shimauchi A, Hosogi M, Munemori E, Ocho K, Morishima T
Pediatr Int 2016 Jan;58(1):8-13. doi: 10.1111/ped.12790. PMID: 26270796
Verheij C, Louwerse A, van der Ende J, Eussen ML, Van Gool AR, Verheij F, Verhulst FC, Greaves-Lord K
J Autism Dev Disord 2015 Dec;45(12):3939-48. doi: 10.1007/s10803-015-2592-5. PMID: 26456972Free PMC Article
Kusaka H, Miyawaki D, Nakai Y, Okamoto H, Futoo E, Goto A, Okada Y, Inoue K
Osaka City Med J 2014 Jun;60(1):1-10. PMID: 25272562
Soleimani F, Teymouri R, Biglarian A
Acta Med Iran 2013 Jul 13;51(6):347-52. PMID: 23852837

Clinical prediction guides

Verheij C, Louwerse A, van der Ende J, Eussen ML, Van Gool AR, Verheij F, Verhulst FC, Greaves-Lord K
J Autism Dev Disord 2015 Dec;45(12):3939-48. doi: 10.1007/s10803-015-2592-5. PMID: 26456972Free PMC Article
McMorris CA, Perry A
Autism 2015 Apr;19(3):272-80. Epub 2014 Jan 24 doi: 10.1177/1362361313518123. PMID: 24463433
Fujiwara T, Kasahara M, Tsujii H, Okuyama M
Child Abuse Negl 2014 Aug;38(8):1283-9. Epub 2014 May 9 doi: 10.1016/j.chiabu.2014.04.007. PMID: 24813254
Soleimani F, Teymouri R, Biglarian A
Acta Med Iran 2013 Jul 13;51(6):347-52. PMID: 23852837
Shandal V, Sundaram SK, Chugani DC, Kumar A, Behen ME, Chugani HT
J Child Neurol 2011 Nov;26(11):1347-54. Epub 2011 Jun 2 doi: 10.1177/0883073811405200. PMID: 21636781

Recent systematic reviews

van Karnebeek CD, Shevell M, Zschocke J, Moeschler JB, Stockler S
Mol Genet Metab 2014 Apr;111(4):428-38. Epub 2014 Jan 24 doi: 10.1016/j.ymgme.2014.01.011. PMID: 24518794
Carigi T, Muratori F, Termine C, Veggiotti P, Derhemi L, Di Nardo R, Rossi G, Balottin U
Curr Clin Pharmacol 2014;9(4):377-86. PMID: 24050746
Fine JG, Semrud-Clikeman M, Bledsoe JC, Musielak KA
Child Neuropsychol 2013;19(2):190-223. Epub 2012 Mar 5 doi: 10.1080/09297049.2011.648923. PMID: 22385012
Rondeau E, Klein LS, Masse A, Bodeau N, Cohen D, Guilé JM
J Autism Dev Disord 2011 Sep;41(9):1267-76. doi: 10.1007/s10803-010-1155-z. PMID: 21153874
Sung M, Fung DS, Cai Y, Ooi YP
Aust N Z J Psychiatry 2010 May;44(5):410-28. doi: 10.3109/00048670903493330. PMID: 20047454

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