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Items: 7

1.

Phenelzine

One of the MONOAMINE OXIDASE INHIBITORS used to treat DEPRESSION; PHOBIC DISORDERS; and PANIC. [from MeSH]

MedGen UID:
18407
Concept ID:
C0031392
Organic Chemical; Pharmacologic Substance
2.

Depression

A melancholy feeling of sadness and despair. [from NCI]

MedGen UID:
8325
Concept ID:
C0011570
Mental or Behavioral Dysfunction
3.

Depression

MedGen UID:
137999
Concept ID:
C0344315
Finding
4.

Depression

MedGen UID:
4229
Concept ID:
C0011581
Mental or Behavioral Dysfunction
5.

Nardelzine

MedGen UID:
288850
Concept ID:
C1563961
Organic Chemical; Pharmacologic Substance
6.

Nardil

MedGen UID:
147259
Concept ID:
C0701388
Organic Chemical; Pharmacologic Substance
7.

Phenelzine sulfate

A hydrazine derivative and a potent non-selective monoamine oxidase (MAO) inhibitor with anxiolytic and antidepressant properties. Phenelzine sulfate irreversibly binds to MAO, thereby blocking the oxidative deamination of monoamines resulting in an increased concentration of biogenic amines and a concurrent decrease in catabolism of monoamine neurotransmitters, norepinephrine and serotonin, in the brain. In addition, through its primary metabolite phenylethylidenehyrazine (PEH), phenelzine causes elevated GABA levels in the caudate-putamen and nucleus accumbens thereby exerting its anxiolytic effects. [from NCI]

MedGen UID:
45852
Concept ID:
C0031393
Organic Chemical; Pharmacologic Substance
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