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Sporadic Parkinson disease

MedGen UID:
1376216
Concept ID:
C4511452
Disease or Syndrome
SNOMED CT: Sporadic Parkinson disease (724761004)

Recent clinical studies

Etiology

Pihlstrøm L, Blauwendraat C, Cappelletti C, Berge-Seidl V, Langmyhr M, Henriksen SP, van de Berg WDJ, Gibbs JR, Cookson MR; International Parkinson Disease Genomics Consortium.; North American Brain Expression Consortium., Singleton AB, Nalls MA, Toft M
Ann Neurol 2018 Jul;84(1):117-129. Epub 2018 Aug 26 doi: 10.1002/ana.25274. PMID: 30146727Free PMC Article
Li Z, Lin Q, Huang W, Tzeng CM
Medicine (Baltimore) 2015 May;94(20):e836. doi: 10.1097/MD.0000000000000836. PMID: 25997059Free PMC Article
Ivatt RM, Whitworth AJ
Autophagy 2014 Aug;10(8):1476-7. Epub 2014 Jun 27 doi: 10.4161/auto.29642. PMID: 24991824Free PMC Article
Murphy KE, Halliday GM
Autophagy 2014 Jul;10(7):1350-1. Epub 2014 May 15 doi: 10.4161/auto.29074. PMID: 24915553Free PMC Article
Krygowska-Wajs A, Cheshire WP Jr, Wszolek ZK, Hubalewska-Dydejczyk A, Jasinska-Myga B, Farrer MJ, Moskala M, Sowa-Staszczak A
Parkinsonism Relat Disord 2009 Nov;15(9):692-6. Epub 2009 May 17 doi: 10.1016/j.parkreldis.2009.04.003. PMID: 19451015Free PMC Article

Diagnosis

Di Fonzo A, Franco G, Barone P, Erro R
Int Rev Neurobiol 2019;149:307-326. Epub 2019 Nov 21 doi: 10.1016/bs.irn.2019.10.007. PMID: 31779818
Kumar S, Jangir DK, Kumar R, Kumari M, Bhavesh NS, Maiti TK
ACS Chem Neurosci 2018 Feb 21;9(2):230-240. Epub 2017 Sep 6 doi: 10.1021/acschemneuro.6b00430. PMID: 28841377
Manno C, Lipari A, Bono V, Taiello AC, La Bella V
J Neurol Sci 2013 Mar 15;326(1-2):104-6. Epub 2013 Feb 4 doi: 10.1016/j.jns.2013.01.009. PMID: 23380453
Chiba-Falek O, Lopez GJ, Nussbaum RL
Mov Disord 2006 Oct;21(10):1703-8. doi: 10.1002/mds.21007. PMID: 16795004
Baba Y, Markopoulou K, Putzke JD, Whaley NR, Farrer MJ, Wszolek ZK, Uitti RJ
Arch Neurol 2006 Apr;63(4):579-83. doi: 10.1001/archneur.63.4.579. PMID: 16606772

Therapy

Zhang J, Mattison HA, Liu C, Ginghina C, Auinger P, McDermott MP, Stewart T, Kang UJ; Parkinson Study Group DATATOP Investigators., Cain KC, Shi M
Acta Neuropathol 2013 Nov;126(5):671-82. Epub 2013 May 4 doi: 10.1007/s00401-013-1121-x. PMID: 23644819Free PMC Article
Raff U, Hutchinson M, Rojas GM, Huete I
Acad Radiol 2006 Jun;13(6):721-7. doi: 10.1016/j.acra.2006.01.049. PMID: 16679274
Hisanaga K, Asagi M, Itoyama Y, Iwasaki Y
Arch Neurol 2001 Oct;58(10):1580-3. doi: 10.1001/archneur.58.10.1580. PMID: 11594915

Prognosis

Ryan E, Seehra G, Sharma P, Sidransky E
Curr Opin Neurol 2019 Aug;32(4):589-596. doi: 10.1097/WCO.0000000000000715. PMID: 31188151
Pihlstrøm L, Blauwendraat C, Cappelletti C, Berge-Seidl V, Langmyhr M, Henriksen SP, van de Berg WDJ, Gibbs JR, Cookson MR; International Parkinson Disease Genomics Consortium.; North American Brain Expression Consortium., Singleton AB, Nalls MA, Toft M
Ann Neurol 2018 Jul;84(1):117-129. Epub 2018 Aug 26 doi: 10.1002/ana.25274. PMID: 30146727Free PMC Article
Peng F, Sun YM, Chen C, Luo SS, Li DK, Wang YX, Yang K, Liu FT, Zuo CT, Ding ZT, An Y, Wu JJ, Wang J
J Neurol Sci 2017 Feb 15;373:23-26. Epub 2016 Dec 9 doi: 10.1016/j.jns.2016.12.009. PMID: 28131193
Ahn TB, Kim SY, Kim JY, Park SS, Lee DS, Min HJ, Kim YK, Kim SE, Kim JM, Kim HJ, Cho J, Jeon BS
Neurology 2008 Jan 1;70(1):43-9. Epub 2007 Jul 11 doi: 10.1212/01.wnl.0000271080.53272.c7. PMID: 17625105
Baba Y, Markopoulou K, Putzke JD, Whaley NR, Farrer MJ, Wszolek ZK, Uitti RJ
Arch Neurol 2006 Apr;63(4):579-83. doi: 10.1001/archneur.63.4.579. PMID: 16606772

Clinical prediction guides

Pihlstrøm L, Blauwendraat C, Cappelletti C, Berge-Seidl V, Langmyhr M, Henriksen SP, van de Berg WDJ, Gibbs JR, Cookson MR; International Parkinson Disease Genomics Consortium.; North American Brain Expression Consortium., Singleton AB, Nalls MA, Toft M
Ann Neurol 2018 Jul;84(1):117-129. Epub 2018 Aug 26 doi: 10.1002/ana.25274. PMID: 30146727Free PMC Article
Ferrer I, Martinez A, Blanco R, Dalfó E, Carmona M
J Neural Transm (Vienna) 2011 May;118(5):821-39. Epub 2010 Sep 23 doi: 10.1007/s00702-010-0482-8. PMID: 20862500
Blackinton J, Kumaran R, van der Brug MP, Ahmad R, Olson L, Galter D, Lees A, Bandopadhyay R, Cookson MR
Neurosci Lett 2009 Mar 6;452(1):8-11. Epub 2009 Jan 6 doi: 10.1016/j.neulet.2008.12.053. PMID: 19146923Free PMC Article
Okubadejo N, Britton A, Crews C, Akinyemi R, Hardy J, Singleton A, Bras J
PLoS One 2008;3(10):e3421. Epub 2008 Oct 17 doi: 10.1371/journal.pone.0003421. PMID: 18927607Free PMC Article
Müller CM, de Vos RA, Maurage CA, Thal DR, Tolnay M, Braak H
J Neuropathol Exp Neurol 2005 Jul;64(7):623-8. doi: 10.1097/01.jnen.0000171652.40083.15. PMID: 16042314

Recent systematic reviews

Huang X, Chen PC, Poole C
Neurology 2004 Jun 22;62(12):2198-202. doi: 10.1212/01.wnl.0000130159.28215.6a. PMID: 15210882

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