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Decreased Concentration

MedGen UID:
858997
•Concept ID:
C3899403
•
Sign or Symptom

Definition

Reduced ability to sustain attention. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDecreased Concentration

Professional guidelines

PubMed

Drug-drug interaction: decreased posaconazole trough concentrations during concomitant flucloxacillin treatment.
Wortman JM, Leegwater E, Van Lammeren-Venema D, Van Nieuwkoop C, Sobels A, Wilms EB
J Antimicrob Chemother 2023 Jun 1;78(6):1471-1475. doi: 10.1093/jac/dkad107. PMID: 37039028
Scabies: update on treatment and efforts for prevention and control in highly endemic settings.
Widaty S, Miranda E, Cornain EF, Rizky LA
J Infect Dev Ctries 2022 Feb 28;16(2):244-251. doi: 10.3855/jidc.15222. PMID: 35298417
Metreleptin treatment of non-HIV lipodystrophy syndromes.
Chevalier B, Lemaitre M, Leguier L, Mapihan KL, Douillard C, Jannin A, Espiard S, Vantyghem MC
Presse Med 2021 Nov;50(3):104070. Epub 2021 Sep 24 doi: 10.1016/j.lpm.2021.104070. PMID: 34571177

Recent clinical studies

Etiology

Metreleptin treatment of non-HIV lipodystrophy syndromes.
Chevalier B, Lemaitre M, Leguier L, Mapihan KL, Douillard C, Jannin A, Espiard S, Vantyghem MC
Presse Med 2021 Nov;50(3):104070. Epub 2021 Sep 24 doi: 10.1016/j.lpm.2021.104070. PMID: 34571177
Decreased concentration of klotho and increased concentration of FGF23 in the cerebrospinal fluid of patients with narcolepsy.
da Paz Oliveira G, Elias RM, Peres Fernandes GB, Moyses R, Tufik S, Bichuetti DB, Coelho FMS
Sleep Med 2021 Feb;78:57-62. Epub 2020 Dec 15 doi: 10.1016/j.sleep.2020.11.037. PMID: 33385780
Low energy availability surrogates correlate with health and performance consequences of Relative Energy Deficiency in Sport.
Ackerman KE, Holtzman B, Cooper KM, Flynn EF, Bruinvels G, Tenforde AS, Popp KL, Simpkin AJ, Parziale AL
Br J Sports Med 2019 May;53(10):628-633. Epub 2018 Jun 2 doi: 10.1136/bjsports-2017-098958. PMID: 29860237
Zinc as a marker of affective disorders.
Siwek M, Szewczyk B, Dudek D, Styczeń K, Sowa-Kućma M, Młyniec K, Siwek A, Witkowski L, Pochwat B, Nowak G
Pharmacol Rep 2013;65(6):1512-8. doi: 10.1016/s1734-1140(13)71512-3. PMID: 24552999
Post concussion syndrome.
Ryan LM, Warden DL
Int Rev Psychiatry 2003 Nov;15(4):310-6. doi: 10.1080/09540260310001606692. PMID: 15276952

Diagnosis

Side Effect Profiles of Selective Serotonin Reuptake Inhibitors: A Cross-Sectional Study in a Naturalistic Setting.
Anagha K, Shihabudheen P, Uvais NA
Prim Care Companion CNS Disord 2021 Jul 29;23(4) doi: 10.4088/PCC.20m02747. PMID: 34324797
Thyroid function in critically ill patients.
Fliers E, Bianco AC, Langouche L, Boelen A
Lancet Diabetes Endocrinol 2015 Oct;3(10):816-25. Epub 2015 Jun 10 doi: 10.1016/S2213-8587(15)00225-9. PMID: 26071885Free PMC Article
Zinc as a marker of affective disorders.
Siwek M, Szewczyk B, Dudek D, Styczeń K, Sowa-Kućma M, Młyniec K, Siwek A, Witkowski L, Pochwat B, Nowak G
Pharmacol Rep 2013;65(6):1512-8. doi: 10.1016/s1734-1140(13)71512-3. PMID: 24552999
Diagnosis and treatment of insomnia.
Passarella S, Duong MT
Am J Health Syst Pharm 2008 May 15;65(10):927-34. doi: 10.2146/ajhp060640. PMID: 18463341
Post concussion syndrome.
Ryan LM, Warden DL
Int Rev Psychiatry 2003 Nov;15(4):310-6. doi: 10.1080/09540260310001606692. PMID: 15276952

Therapy

Scabies: update on treatment and efforts for prevention and control in highly endemic settings.
Widaty S, Miranda E, Cornain EF, Rizky LA
J Infect Dev Ctries 2022 Feb 28;16(2):244-251. doi: 10.3855/jidc.15222. PMID: 35298417
Metreleptin treatment of non-HIV lipodystrophy syndromes.
Chevalier B, Lemaitre M, Leguier L, Mapihan KL, Douillard C, Jannin A, Espiard S, Vantyghem MC
Presse Med 2021 Nov;50(3):104070. Epub 2021 Sep 24 doi: 10.1016/j.lpm.2021.104070. PMID: 34571177
Side Effect Profiles of Selective Serotonin Reuptake Inhibitors: A Cross-Sectional Study in a Naturalistic Setting.
Anagha K, Shihabudheen P, Uvais NA
Prim Care Companion CNS Disord 2021 Jul 29;23(4) doi: 10.4088/PCC.20m02747. PMID: 34324797
Thymosin beta 4 regulation of actin in sepsis.
Belsky JB, Rivers EP, Filbin MR, Lee PJ, Morris DC
Expert Opin Biol Ther 2018 Jul;18(sup1):193-197. Epub 2018 Mar 6 doi: 10.1080/14712598.2018.1448381. PMID: 29508629Free PMC Article
Diagnosis and treatment of insomnia.
Passarella S, Duong MT
Am J Health Syst Pharm 2008 May 15;65(10):927-34. doi: 10.2146/ajhp060640. PMID: 18463341

Prognosis

Early and late predictors of postoperative neurocognitive dysfunction in cardiac surgery.
Urcun YS, Altun Y, Pala AA
Ideggyogy Sz 2022 Jul 30;75(7-08):231-240. doi: 10.18071/isz.75.0231. PMID: 35916609
Decreased Concentration of Fibroblast Growth Factor 23 (FGF-23) as a Result of Supplementation with Selenium and Coenzyme Q(10) in an Elderly Swedish Population: A Sub-Analysis.
Alehagen U, Aaseth J, Larsson A, Alexander J
Cells 2022 Feb 1;11(3) doi: 10.3390/cells11030509. PMID: 35159318Free PMC Article
Clinical significance of fluid biomarkers in Alzheimer's Disease.
Lewczuk P, Łukaszewicz-Zając M, Mroczko P, Kornhuber J
Pharmacol Rep 2020 Jun;72(3):528-542. Epub 2020 May 8 doi: 10.1007/s43440-020-00107-0. PMID: 32385624Free PMC Article
Arginine supplementation for prevention of necrotising enterocolitis in preterm infants.
Shah PS, Shah VS, Kelly LE
Cochrane Database Syst Rev 2017 Apr 11;4(4):CD004339. doi: 10.1002/14651858.CD004339.pub4. PMID: 28399330Free PMC Article
Thyroid function in critically ill patients.
Fliers E, Bianco AC, Langouche L, Boelen A
Lancet Diabetes Endocrinol 2015 Oct;3(10):816-25. Epub 2015 Jun 10 doi: 10.1016/S2213-8587(15)00225-9. PMID: 26071885Free PMC Article

Clinical prediction guides

Ovariectomy aggravates the pathophysiological response to exertional heat stroke in mice.
Rentería LI, Zheng X, Valera I, Machin DR, Garcia CK, Leon LR, Laitano O
J Appl Physiol (1985) 2023 May 1;134(5):1224-1231. Epub 2023 Apr 6 doi: 10.1152/japplphysiol.00092.2023. PMID: 37022961Free PMC Article
Nesfatin-1 as a potential marker for functional hypothalamic amenorrhea.
Szeliga A, Podfigurna A, Meczekalski B
Gynecol Endocrinol 2022 Nov;38(11):992-996. Epub 2022 Sep 23 doi: 10.1080/09513590.2022.2126455. PMID: 36150403
Side Effect Profiles of Selective Serotonin Reuptake Inhibitors: A Cross-Sectional Study in a Naturalistic Setting.
Anagha K, Shihabudheen P, Uvais NA
Prim Care Companion CNS Disord 2021 Jul 29;23(4) doi: 10.4088/PCC.20m02747. PMID: 34324797
Review: Chemical Pathology of Homocysteine VI. Aging, Cellular Senescence, and Mitochondrial Dysfunction.
McCully KS
Ann Clin Lab Sci 2018 Sep;48(5):677-687. PMID: 30373877
Is yawning an arousal defense reflex?
Askenasy JJ
J Psychol 1989 Nov;123(6):609-21. doi: 10.1080/00223980.1989.10543014. PMID: 2558182

Recent systematic reviews

Safety and risk assessment of psychedelic psychotherapy: A meta-analysis and systematic review.
Romeo B, Kervadec E, Fauvel B, Strika-Bruneau L, Amirouche A, Verroust V, Piolino P, Benyamina A
Psychiatry Res 2024 May;335:115880. Epub 2024 Mar 31 doi: 10.1016/j.psychres.2024.115880. PMID: 38579460
The effect of vitamin D supplementation on oxidative stress and inflammatory biomarkers in pregnant women: a systematic review and meta-analysis of clinical trials.
Motamed S, Nikooyeh B, Anari R, Motamed S, Mokhtari Z, Neyestani T
BMC Pregnancy Childbirth 2022 Nov 5;22(1):816. doi: 10.1186/s12884-022-05132-w. PMID: 36335311Free PMC Article
Arginine supplementation for prevention of necrotising enterocolitis in preterm infants.
Shah PS, Shah VS, Kelly LE
Cochrane Database Syst Rev 2017 Apr 11;4(4):CD004339. doi: 10.1002/14651858.CD004339.pub4. PMID: 28399330Free PMC Article
Mechanism of Action of Spinal Mobilizations: A Systematic Review.
Lascurain-Aguirrebeña I, Newham D, Critchley DJ
Spine (Phila Pa 1976) 2016 Jan;41(2):159-72. doi: 10.1097/BRS.0000000000001151. PMID: 26751060
Herbal-drug therapy interactions: a focus on dementia.
Gold JL, Laxer DA, Dergal JM, Lanctôt KL, Rochon PA
Curr Opin Clin Nutr Metab Care 2001 Jan;4(1):29-34. doi: 10.1097/00075197-200101000-00006. PMID: 11122556

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