From HPO
Elevated hemoglobin A1c- MedGen UID:
- 892798
- •Concept ID:
- C4073162
- •
- Finding
An increased concentration of hemoglobin A1c (HbA1c), which is the product of nonenzymatic attachment of a hexose molecule to the N-terminal amino acid of the hemoglobin molecule. This reaction is dependent on blood glucose concentration, and therefore reflects the mean glucose concentration over the previous 8 to 12 weeks. The HbA1c level provides a better indication of long-term glycemic control than one-time blood or urinary glucose measurements.
Anti-glutamic acid decarboxylase antibody positivity- MedGen UID:
- 1370651
- •Concept ID:
- C4476703
- •
- Laboratory or Test Result
The presence of autoantibodies (immunoglobulins) in the serum that react against glutamic acid decarboxylase.
Hyperglycemia- MedGen UID:
- 5689
- •Concept ID:
- C0020456
- •
- Disease or Syndrome
An increased concentration of glucose in the blood.
Transitory neonatal diabetes mellitus- MedGen UID:
- 449530
- •Concept ID:
- C0342273
- •
- Disease or Syndrome
Hyperglycemia in the first month of life due to a genetically determined defect in the structure, secretion and/or function of insulin that resolves spontaneously within nine months of onset.
Reduced C-peptide level- MedGen UID:
- 909412
- •Concept ID:
- C4280764
- •
- Finding
A decreased concentration of C-peptide in the circulation. Since C-peptide is secreted in equimolar amounts to insulin, this feature correlates with reduced insulin secretion.
- Abnormality of blood and blood-forming tissues
- Abnormality of metabolism/homeostasis
- Abnormality of the immune system