U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Venous thromboembolism

MedGen UID:
348285
Concept ID:
C1861172
Disease or Syndrome
Synonyms: Thromboembolism, Venous; Venous Thromboembolism
 
Monarch Initiative: MONDO:0005399
OMIM®: 188050

Definition

Occlusion of the lumen of a vein by a thrombus that has migrated from a distal site via the blood stream. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVVenous thromboembolism

Professional guidelines

PubMed

Barbhaiya M, Zuily S, Naden R, Hendry A, Manneville F, Amigo MC, Amoura Z, Andrade D, Andreoli L, Artim-Esen B, Atsumi T, Avcin T, Belmont HM, Bertolaccini ML, Branch DW, Carvalheiras G, Casini A, Cervera R, Cohen H, Costedoat-Chalumeau N, Crowther M, de Jesus G, Delluc A, Desai S, De Sancho M, Devreese KM, Diz-Kucukkaya R, Duarte-Garcia A, Frances C, Garcia D, Gris JC, Jordan N, Leaf RK, Kello N, Knight JS, Laskin C, Lee AI, Legault K, Levine SR, Levy RA, Limper M, Lockshin MD, Mayer-Pickel K, Musial J, Meroni PL, Orsolini G, Ortel TL, Pengo V, Petri M, Pons-Estel G, Gomez-Puerta JA, Raimboug Q, Roubey R, Sanna G, Seshan SV, Sciascia S, Tektonidou MG, Tincani A, Wahl D, Willis R, Yelnik C, Zuily C, Guillemin F, Costenbader K, Erkan D; ACR/EULAR APS Classification Criteria Collaborators
Arthritis Rheumatol 2023 Oct;75(10):1687-1702. Epub 2023 Aug 28 doi: 10.1002/art.42624. PMID: 37635643
Key NS, Khorana AA, Kuderer NM, Bohlke K, Lee AYY, Arcelus JI, Wong SL, Balaban EP, Flowers CR, Francis CW, Gates LE, Kakkar AK, Levine MN, Liebman HA, Tempero MA, Lyman GH, Falanga A
J Clin Oncol 2020 Feb 10;38(5):496-520. Epub 2019 Aug 5 doi: 10.1200/JCO.19.01461. PMID: 31381464
American College of Obstetricians and Gynecologists' Committee on Practice Bulletins—Obstetrics
Obstet Gynecol 2018 Jul;132(1):e1-e17. doi: 10.1097/AOG.0000000000002706. PMID: 29939938

Recent clinical studies

Etiology

Lutsey PL, Zakai NA
Nat Rev Cardiol 2023 Apr;20(4):248-262. Epub 2022 Oct 18 doi: 10.1038/s41569-022-00787-6. PMID: 36258120Free PMC Article
Mount HR, Rich M, Putnam MS
Am Fam Physician 2022 Apr 1;105(4):377-385. PMID: 35426644
Golemi I, Salazar Adum JP, Tafur A, Caprini J
Dis Mon 2019 Aug;65(8):249-298. Epub 2019 Jan 9 doi: 10.1016/j.disamonth.2018.12.005. PMID: 30638566
Bartholomew JR
Cleve Clin J Med 2017 Dec;84(12 Suppl 3):39-46. doi: 10.3949/ccjm.84.s3.04. PMID: 29257737
Jaffer AK
Cleve Clin J Med 2008 Apr;75 Suppl 3:S2. PMID: 18496912

Diagnosis

Lutsey PL, Zakai NA
Nat Rev Cardiol 2023 Apr;20(4):248-262. Epub 2022 Oct 18 doi: 10.1038/s41569-022-00787-6. PMID: 36258120Free PMC Article
Bukhari S, Fatima S, Barakat AF, Fogerty AE, Weinberg I, Elgendy IY
Eur J Intern Med 2022 Mar;97:8-17. Epub 2021 Dec 20 doi: 10.1016/j.ejim.2021.12.013. PMID: 34949492
Martin KA, Beyer-Westendorf J, Davidson BL, Huisman MV, Sandset PM, Moll S
J Thromb Haemost 2021 Aug;19(8):1874-1882. Epub 2021 Jul 14 doi: 10.1111/jth.15358. PMID: 34259389
Khan F, Tritschler T, Kahn SR, Rodger MA
Lancet 2021 Jul 3;398(10294):64-77. Epub 2021 May 10 doi: 10.1016/S0140-6736(20)32658-1. PMID: 33984268
Weitz JI, Fredenburgh JC, Eikelboom JW
J Am Coll Cardiol 2017 Nov 7;70(19):2411-2420. doi: 10.1016/j.jacc.2017.09.024. PMID: 29096812

Therapy

Fernando SM, Tran A, Cheng W, Sadeghirad B, Arabi YM, Cook DJ, Møller MH, Mehta S, Fowler RA, Burns KEA, Wells PS, Carrier M, Crowther MA, Scales DC, English SW, Kyeremanteng K, Kanji S, Kho ME, Rochwerg B
Chest 2022 Feb;161(2):418-428. Epub 2021 Aug 19 doi: 10.1016/j.chest.2021.08.050. PMID: 34419428
Key NS, Khorana AA, Kuderer NM, Bohlke K, Lee AYY, Arcelus JI, Wong SL, Balaban EP, Flowers CR, Francis CW, Gates LE, Kakkar AK, Levine MN, Liebman HA, Tempero MA, Lyman GH, Falanga A
J Clin Oncol 2020 Feb 10;38(5):496-520. Epub 2019 Aug 5 doi: 10.1200/JCO.19.01461. PMID: 31381464
Ay C, Beyer-Westendorf J, Pabinger I
Ann Oncol 2019 Jun 1;30(6):897-907. doi: 10.1093/annonc/mdz111. PMID: 30918939Free PMC Article
Elsebaie MAT, van Es N, Langston A, Büller HR, Gaddh M
J Thromb Haemost 2019 Apr;17(4):645-656. Epub 2019 Feb 25 doi: 10.1111/jth.14398. PMID: 30690830
Carrier M, Abou-Nassar K, Mallick R, Tagalakis V, Shivakumar S, Schattner A, Kuruvilla P, Hill D, Spadafora S, Marquis K, Trinkaus M, Tomiak A, Lee AYY, Gross PL, Lazo-Langner A, El-Maraghi R, Goss G, Le Gal G, Stewart D, Ramsay T, Rodger M, Witham D, Wells PS; AVERT Investigators
N Engl J Med 2019 Feb 21;380(8):711-719. Epub 2018 Dec 4 doi: 10.1056/NEJMoa1814468. PMID: 30511879

Prognosis

Goldenberg NA, Kittelson JM, Abshire TC, Bonaca M, Casella JF, Dale RA, Halperin JL, Hamblin F, Kessler CM, Manco-Johnson MJ, Sidonio RF, Spyropoulos AC, Steg PG, Turpie AGG, Schulman S; Kids-DOTT Trial Investigators and the ATLAS Group
JAMA 2022 Jan 11;327(2):129-137. doi: 10.1001/jama.2021.23182. PMID: 35015038Free PMC Article
Poor HD
Chest 2021 Oct;160(4):1471-1480. Epub 2021 Jun 19 doi: 10.1016/j.chest.2021.06.016. PMID: 34153340Free PMC Article
Zhan H, Chen H, Liu C, Cheng L, Yan S, Li H, Li Y
Clin Appl Thromb Hemost 2021 Jan-Dec;27:10760296211010976. doi: 10.1177/10760296211010976. PMID: 33926262Free PMC Article
Arabi YM, Al-Hameed F, Burns KEA, Mehta S, Alsolamy SJ, Alshahrani MS, Mandourah Y, Almekhlafi GA, Almaani M, Al Bshabshe A, Finfer S, Arshad Z, Khalid I, Mehta Y, Gaur A, Hawa H, Buscher H, Lababidi H, Al Aithan A, Abdukahil SAI, Jose J, Afesh LY, Al-Dawood A; Saudi Critical Care Trials Group
N Engl J Med 2019 Apr 4;380(14):1305-1315. Epub 2019 Feb 18 doi: 10.1056/NEJMoa1816150. PMID: 30779530
Getahun D, Nash R, Flanders WD, Baird TC, Becerra-Culqui TA, Cromwell L, Hunkeler E, Lash TL, Millman A, Quinn VP, Robinson B, Roblin D, Silverberg MJ, Safer J, Slovis J, Tangpricha V, Goodman M
Ann Intern Med 2018 Aug 21;169(4):205-213. Epub 2018 Jul 10 doi: 10.7326/M17-2785. PMID: 29987313Free PMC Article

Clinical prediction guides

Chopard R, Albertsen IE, Piazza G
JAMA 2020 Nov 3;324(17):1765-1776. doi: 10.1001/jama.2020.17272. PMID: 33141212
Hogan M, Berger JS
Vasc Med 2020 Apr;25(2):160-173. Epub 2020 Mar 20 doi: 10.1177/1358863X19898253. PMID: 32195628
Giordano NJ, Jansson PS, Young MN, Hagan KA, Kabrhel C
Tech Vasc Interv Radiol 2017 Sep;20(3):135-140. Epub 2017 Jul 5 doi: 10.1053/j.tvir.2017.07.002. PMID: 29029707
Cosmi B
J Thromb Haemost 2015 Jul;13(7):1175-83. Epub 2015 May 25 doi: 10.1111/jth.12986. PMID: 25903684
Khorana AA, Kuderer NM, Culakova E, Lyman GH, Francis CW
Blood 2008 May 15;111(10):4902-7. Epub 2008 Jan 23 doi: 10.1182/blood-2007-10-116327. PMID: 18216292Free PMC Article

Recent systematic reviews

Wu S, Lv M, Chen J, Jiang S, Chen M, Fang Z, Zeng Z, Qian J, Xu W, Guan C, Zhang J
Support Care Cancer 2022 Dec;30(12):10407-10420. Epub 2022 Nov 1 doi: 10.1007/s00520-022-07433-4. PMID: 36318341
Hayssen H, Cires-Drouet R, Englum B, Nguyen P, Sahoo S, Mayorga-Carlin M, Siddiqui T, Turner D, Yesha Y, Sorkin JD, Lal BK
J Vasc Surg Venous Lymphat Disord 2022 Nov;10(6):1401-1409.e7. Epub 2022 Aug 2 doi: 10.1016/j.jvsv.2022.05.003. PMID: 35926802Free PMC Article
Tøndel BG, Morelli VM, Hansen JB, Braekkan SK
J Thromb Haemost 2022 Oct;20(10):2173-2186. Epub 2022 Jul 28 doi: 10.1111/jth.15813. PMID: 35815351Free PMC Article
Chopard R, Albertsen IE, Piazza G
JAMA 2020 Nov 3;324(17):1765-1776. doi: 10.1001/jama.2020.17272. PMID: 33141212
Key NS, Khorana AA, Kuderer NM, Bohlke K, Lee AYY, Arcelus JI, Wong SL, Balaban EP, Flowers CR, Francis CW, Gates LE, Kakkar AK, Levine MN, Liebman HA, Tempero MA, Lyman GH, Falanga A
J Clin Oncol 2020 Feb 10;38(5):496-520. Epub 2019 Aug 5 doi: 10.1200/JCO.19.01461. PMID: 31381464

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...