U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Malaria, cerebral, susceptibility to

MedGen UID:
344501
•Concept ID:
C1855457
•
Finding
Synonym: MALARIA, CEREBRAL, SUSCEPTIBILITY TO
 
OMIM®: 147840; 173510; 191160; 611162

Professional guidelines

PubMed

The genotypes of GYPA and GYPB carrying the MNSs antigens are not associated with cerebral malaria.
Naka I, Ohashi J, Patarapotikul J, Hananantachai H, Wilairatana P, Looareesuwan S, Tokunaga K
J Hum Genet 2007;52(5):476-479. Epub 2007 Mar 20 doi: 10.1007/s10038-007-0133-6. PMID: 17372674

Recent clinical studies

Etiology

Folic acid supplementation and malaria susceptibility and severity among people taking antifolate antimalarial drugs in endemic areas.
Crider K, Williams J, Qi YP, Gutman J, Yeung L, Mai C, Finkelstain J, Mehta S, Pons-Duran C, Menéndez C, Moraleda C, Rogers L, Daniels K, Green P
Cochrane Database Syst Rev 2022 Feb 1;2(2022) doi: 10.1002/14651858.CD014217. PMID: 36321557Free PMC Article
microRNA-27a and microRNA-146a SNP in cerebral malaria.
Wah ST, Hananantachai H, Patarapotikul J, Ohashi J, Naka I, Nuchnoi P
Mol Genet Genomic Med 2019 Feb;7(2):e00529. Epub 2019 Jan 1 doi: 10.1002/mgg3.529. PMID: 30599464Free PMC Article
Pregnancy-associated malaria and malaria in infants: an old problem with present consequences.
Moya-Alvarez V, Abellana R, Cot M
Malar J 2014 Jul 11;13:271. doi: 10.1186/1475-2875-13-271. PMID: 25015559Free PMC Article
Cerebral malaria.
Garg RK
J Assoc Physicians India 2000 Oct;48(10):1004-13. PMID: 11200901
The treatment of malaria.
White NJ
N Engl J Med 1996 Sep 12;335(11):800-6. doi: 10.1056/NEJM199609123351107. PMID: 8703186

Diagnosis

Folic acid supplementation and malaria susceptibility and severity among people taking antifolate antimalarial drugs in endemic areas.
Crider K, Williams J, Qi YP, Gutman J, Yeung L, Mai C, Finkelstain J, Mehta S, Pons-Duran C, Menéndez C, Moraleda C, Rogers L, Daniels K, Green P
Cochrane Database Syst Rev 2022 Feb 1;2(2022) doi: 10.1002/14651858.CD014217. PMID: 36321557Free PMC Article
Parasitic and fungal infections.
Deigendesch N, Costa Nunez J, Stenzel W
Handb Clin Neurol 2017;145:245-262. doi: 10.1016/B978-0-12-802395-2.00018-3. PMID: 28987173
Cerebral malaria in children: using the retina to study the brain.
MacCormick IJ, Beare NA, Taylor TE, Barrera V, White VA, Hiscott P, Molyneux ME, Dhillon B, Harding SP
Brain 2014 Aug;137(Pt 8):2119-42. Epub 2014 Feb 26 doi: 10.1093/brain/awu001. PMID: 24578549Free PMC Article
Cerebral malaria.
Garg RK
J Assoc Physicians India 2000 Oct;48(10):1004-13. PMID: 11200901
The treatment of malaria.
White NJ
N Engl J Med 1996 Sep 12;335(11):800-6. doi: 10.1056/NEJM199609123351107. PMID: 8703186

Therapy

Anti-malaria drug artesunate prevents development of amyloid-β pathology in mice by upregulating PICALM at the blood-brain barrier.
Kisler K, Sagare AP, Lazic D, Bazzi S, Lawson E, Hsu CJ, Wang Y, Ramanathan A, Nelson AR, Zhao Z, Zlokovic BV
Mol Neurodegener 2023 Jan 27;18(1):7. doi: 10.1186/s13024-023-00597-5. PMID: 36707892Free PMC Article
Folic acid supplementation and malaria susceptibility and severity among people taking antifolate antimalarial drugs in endemic areas.
Crider K, Williams J, Qi YP, Gutman J, Yeung L, Mai C, Finkelstain J, Mehta S, Pons-Duran C, Menéndez C, Moraleda C, Rogers L, Daniels K, Green P
Cochrane Database Syst Rev 2022 Feb 1;2(2022) doi: 10.1002/14651858.CD014217. PMID: 36321557Free PMC Article
Pregnancy-associated malaria and malaria in infants: an old problem with present consequences.
Moya-Alvarez V, Abellana R, Cot M
Malar J 2014 Jul 11;13:271. doi: 10.1186/1475-2875-13-271. PMID: 25015559Free PMC Article
Cerebral protection: inflammation, endothelial dysfunction, and postoperative cognitive dysfunction.
Riedel B, Browne K, Silbert B
Curr Opin Anaesthesiol 2014 Feb;27(1):89-97. doi: 10.1097/ACO.0000000000000032. PMID: 24300462
The treatment of malaria.
White NJ
N Engl J Med 1996 Sep 12;335(11):800-6. doi: 10.1056/NEJM199609123351107. PMID: 8703186

Prognosis

Folic acid supplementation and malaria susceptibility and severity among people taking antifolate antimalarial drugs in endemic areas.
Crider K, Williams J, Qi YP, Gutman J, Yeung L, Mai C, Finkelstain J, Mehta S, Pons-Duran C, Menéndez C, Moraleda C, Rogers L, Daniels K, Green P
Cochrane Database Syst Rev 2022 Feb 1;2(2022) doi: 10.1002/14651858.CD014217. PMID: 36321557Free PMC Article
Parasitic and fungal infections.
Deigendesch N, Costa Nunez J, Stenzel W
Handb Clin Neurol 2017;145:245-262. doi: 10.1016/B978-0-12-802395-2.00018-3. PMID: 28987173
Cerebral malaria in children: using the retina to study the brain.
MacCormick IJ, Beare NA, Taylor TE, Barrera V, White VA, Hiscott P, Molyneux ME, Dhillon B, Harding SP
Brain 2014 Aug;137(Pt 8):2119-42. Epub 2014 Feb 26 doi: 10.1093/brain/awu001. PMID: 24578549Free PMC Article
Cerebral malaria.
Garg RK
J Assoc Physicians India 2000 Oct;48(10):1004-13. PMID: 11200901
The treatment of malaria.
White NJ
N Engl J Med 1996 Sep 12;335(11):800-6. doi: 10.1056/NEJM199609123351107. PMID: 8703186

Clinical prediction guides

HMOX1 STR polymorphism and malaria: an analysis of a large clinical dataset.
Hamilton F, Mitchell R, Cunnington A, Ghazal P, Timpson NJ
Malar J 2022 Nov 17;21(1):342. doi: 10.1186/s12936-022-04352-x. PMID: 36397106Free PMC Article
Folic acid supplementation and malaria susceptibility and severity among people taking antifolate antimalarial drugs in endemic areas.
Crider K, Williams J, Qi YP, Gutman J, Yeung L, Mai C, Finkelstain J, Mehta S, Pons-Duran C, Menéndez C, Moraleda C, Rogers L, Daniels K, Green P
Cochrane Database Syst Rev 2022 Feb 1;2(2022) doi: 10.1002/14651858.CD014217. PMID: 36321557Free PMC Article
Complement activation in malaria: friend or foe?
Biryukov S, Stoute JA
Trends Mol Med 2014 May;20(5):293-301. Epub 2014 Feb 6 doi: 10.1016/j.molmed.2014.01.001. PMID: 24508275
Cerebral protection: inflammation, endothelial dysfunction, and postoperative cognitive dysfunction.
Riedel B, Browne K, Silbert B
Curr Opin Anaesthesiol 2014 Feb;27(1):89-97. doi: 10.1097/ACO.0000000000000032. PMID: 24300462
Host responses in malaria disease evaluated through nuclear magnetic resonance-based metabonomics.
Sonawat HM, Sharma S
Clin Lab Med 2012 Jun;32(2):129-42. doi: 10.1016/j.cll.2012.04.005. PMID: 22726995

Recent systematic reviews

Folic acid supplementation and malaria susceptibility and severity among people taking antifolate antimalarial drugs in endemic areas.
Crider K, Williams J, Qi YP, Gutman J, Yeung L, Mai C, Finkelstain J, Mehta S, Pons-Duran C, Menéndez C, Moraleda C, Rogers L, Daniels K, Green P
Cochrane Database Syst Rev 2022 Feb 1;2(2022) doi: 10.1002/14651858.CD014217. PMID: 36321557Free PMC Article

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • ClinVar
      Related medical variations
    • OMIM
      Related records in OMIM
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed
    • PubMed (OMIM)
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...