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Breast neoplasm

MedGen UID:
264172
Concept ID:
C1458155
Neoplastic Process
Synonyms: Breast Neoplasms; Breast tumor; Neoplasm of breast; Neoplasm of the breast
SNOMED CT: Neoplasm of breast (126926005); Breast tumor (126926005); Tumor of breast (126926005)
 
Related genes: BRIP1, PALB2, CHEK2, RB1CC1, PPM1D, RAD54L, XRCC3, TP53, STK11, RAD51D, RAD51C, RAD51, PTEN, PIK3CA, PHB1, SLC22A18, NQO2, KRAS, HMMR, ESR1, CDH1, CASP8, BRCA2, BRCA1, BARD1, ATM, AKT1
 
HPO: HP:0100013
Monarch Initiative: MONDO:0021100

Definition

A tumor (abnormal growth of tissue) of the breast. [from HPO]

Term Hierarchy

Professional guidelines

PubMed

Rakha EA, Pinder SE, Bartlett JM, Ibrahim M, Starczynski J, Carder PJ, Provenzano E, Hanby A, Hales S, Lee AH, Ellis IO; National Coordinating Committee for Breast Pathology.
J Clin Pathol 2015 Feb;68(2):93-9. Epub 2014 Dec 8 doi: 10.1136/jclinpath-2014-202571. PMID: 25488926Free PMC Article
Ramakrishna N, Temin S, Chandarlapaty S, Crews JR, Davidson NE, Esteva FJ, Giordano SH, Gonzalez-Angulo AM, Kirshner JJ, Krop I, Levinson J, Modi S, Patt DA, Perez EA, Perlmutter J, Winer EP, Lin NU
J Clin Oncol 2014 Jul 1;32(19):2100-8. Epub 2014 May 5 doi: 10.1200/JCO.2013.54.0955. PMID: 24799487Free PMC Article
Giordano SH, Temin S, Kirshner JJ, Chandarlapaty S, Crews JR, Davidson NE, Esteva FJ, Gonzalez-Angulo AM, Krop I, Levinson J, Lin NU, Modi S, Patt DA, Perez EA, Perlmutter J, Ramakrishna N, Winer EP; American Society of Clinical Oncology.
J Clin Oncol 2014 Jul 1;32(19):2078-99. Epub 2014 May 5 doi: 10.1200/JCO.2013.54.0948. PMID: 24799465Free PMC Article
Wolff AC, Hammond ME, Hicks DG, Dowsett M, McShane LM, Allison KH, Allred DC, Bartlett JM, Bilous M, Fitzgibbons P, Hanna W, Jenkins RB, Mangu PB, Paik S, Perez EA, Press MF, Spears PA, Vance GH, Viale G, Hayes DF; American Society of Clinical Oncology.; College of American Pathologists.
Arch Pathol Lab Med 2014 Feb;138(2):241-56. Epub 2013 Oct 7 doi: 10.5858/arpa.2013-0953-SA. PMID: 24099077Free PMC Article
Moyer VA; U.S. Preventive Services Task Force.
Ann Intern Med 2013 Nov 19;159(10):698-708. doi: 10.7326/0003-4819-159-10-201311190-00717. PMID: 24061412
Senkus E, Kyriakides S, Penault-Llorca F, Poortmans P, Thompson A, Zackrisson S, Cardoso F; ESMO Guidelines Working Group.
Ann Oncol 2013 Oct;24 Suppl 6:vi7-23. Epub 2013 Aug 22 doi: 10.1093/annonc/mdt284. PMID: 23970019
Goldhirsch A, Winer EP, Coates AS, Gelber RD, Piccart-Gebhart M, Thürlimann B, Senn HJ; Panel members.
Ann Oncol 2013 Sep;24(9):2206-23. Epub 2013 Aug 4 doi: 10.1093/annonc/mdt303. PMID: 23917950Free PMC Article
Visvanathan K, Hurley P, Bantug E, Brown P, Col NF, Cuzick J, Davidson NE, Decensi A, Fabian C, Ford L, Garber J, Katapodi M, Kramer B, Morrow M, Parker B, Runowicz C, Vogel VG 3rd, Wade JL, Lippman SM
J Clin Oncol 2013 Aug 10;31(23):2942-62. Epub 2013 Jul 8 doi: 10.1200/JCO.2013.49.3122. PMID: 23835710
Berliner JL, Fay AM, Cummings SA, Burnett B, Tillmanns T
J Genet Couns 2013 Apr;22(2):155-63. Epub 2012 Nov 28 doi: 10.1007/s10897-012-9547-1. PMID: 23188549
Febbo PG, Ladanyi M, Aldape KD, De Marzo AM, Hammond ME, Hayes DF, Iafrate AJ, Kelley RK, Marcucci G, Ogino S, Pao W, Sgroi DC, Birkeland ML
J Natl Compr Canc Netw 2011 Nov;9 Suppl 5:S1-32; quiz S33. doi: 10.6004/jnccn.2011.0137. PMID: 22138009
Evaluation of Genomic Applications in Practice and Prevention (EGAPP) Working Group.
Genet Med 2009 Jan;11(1):66-73. doi: 10.1097/GIM.0b013e3181928f56. PMID: 19125125Free PMC Article
Sturgeon CM, Duffy MJ, Stenman UH, Lilja H, Brünner N, Chan DW, Babaian R, Bast RC Jr, Dowell B, Esteva FJ, Haglund C, Harbeck N, Hayes DF, Holten-Andersen M, Klee GG, Lamerz R, Looijenga LH, Molina R, Nielsen HJ, Rittenhouse H, Semjonow A, Shih IeM, Sibley P, Sölétormos G, Stephan C, Sokoll L, Hoffman BR, Diamandis EP; National Academy of Clinical Biochemistry.
Clin Chem 2008 Dec;54(12):e11-79. doi: 10.1373/clinchem.2008.105601. PMID: 19042984
Harris L, Fritsche H, Mennel R, Norton L, Ravdin P, Taube S, Somerfield MR, Hayes DF, Bast RC Jr; American Society of Clinical Oncology.
J Clin Oncol 2007 Nov 20;25(33):5287-312. Epub 2007 Oct 22 doi: 10.1200/JCO.2007.14.2364. PMID: 17954709

External

Tumour profiling tests to guide adjuvant chemotherapy decisions in early breast cancer, NICE, 2018

National Comprehensive Cancer Network Clinical Practice Guidelines in Oncology. Breast Cancer

DG10 Gene expression profiling and expanded immunohistochemistry tests for guiding adjuvant chemotherapy decisions in early breast cancer management: MammaPrint, Oncotype DX, IHC4 and Mammostrat: information for the public

Technology Assessment on Genetic Testing or Molecular Pathology Testing of Cancers with Unknown Primary Site to Determine Origin

Suggested Reading

PubMed

Cardoso F, van't Veer LJ, Bogaerts J, Slaets L, Viale G, Delaloge S, Pierga JY, Brain E, Causeret S, DeLorenzi M, Glas AM, Golfinopoulos V, Goulioti T, Knox S, Matos E, Meulemans B, Neijenhuis PA, Nitz U, Passalacqua R, Ravdin P, Rubio IT, Saghatchian M, Smilde TJ, Sotiriou C, Stork L, Straehle C, Thomas G, Thompson AM, van der Hoeven JM, Vuylsteke P, Bernards R, Tryfonidis K, Rutgers E, Piccart M; MINDACT Investigators.
N Engl J Med 2016 Aug 25;375(8):717-29. doi: 10.1056/NEJMoa1602253. PMID: 27557300
Ward S, Scope A, Rafia R, Pandor A, Harnan S, Evans P, Wyld L
Health Technol Assess 2013 Oct;17(44):1-302. doi: 10.3310/hta17440. PMID: 24088296Free PMC Article

Recent clinical studies

Etiology

Li R, Li J, Chen S, Xiao B, Liu L, Zhu N
Biomed Res Int 2021;2021:7739628. Epub 2021 Nov 17 doi: 10.1155/2021/7739628. PMID: 34840980Free PMC Article
Tariq MU, Idress R, Qureshi MB, Kayani N
Breast J 2020 Feb;26(2):211-215. Epub 2019 Sep 18 doi: 10.1111/tbj.13521. PMID: 31532003
De Matos JC, Pelloso SM, De Barros Carvalho MD
Rev Lat Am Enfermagem 2010 May-Jun;18(3):352-9. doi: 10.1590/s0104-11692010000300009. PMID: 20721423
Peihong S, Perry F
Ethiop Med J 2007 Jan;45(1):79-83. PMID: 17642161
Wang X, Zou S
J Tongji Med Univ 2001;21(3):231-2. doi: 10.1007/BF02886438. PMID: 12539585

Diagnosis

Sun C, Lu Q, Zhang X, Zhang Y, Jia S, Wang J, Zhu H, He W, Zhang Z
Medicine (Baltimore) 2021 Aug 27;100(34):e26970. doi: 10.1097/MD.0000000000026970. PMID: 34449464Free PMC Article
Raphael S, Onyedi CE, Nwana EJC, Garba ES
West Afr J Med 2021 Jul 29;38(7):701-704. PMID: 34331529
Al-Farsi A, Al-Brashdi A, Al-Salhi S, Al-Rahbi N, Al-Rahbi S, Al-Masqari M, Al-Manji Z, Al-Umairi RS
Sultan Qaboos Univ Med J 2020 Aug;20(3):e368-e371. Epub 2020 Oct 5 doi: 10.18295/squmj.2020.20.03.019. PMID: 33110655Free PMC Article
Chen JM, Bai JY, Yang KX
IUBMB Life 2018 Jun;70(6):491-500. Epub 2018 Apr 10 doi: 10.1002/iub.1749. PMID: 29637742
Binesh F, Vahedian H, Akhavan A, Hakiminia M
BMJ Case Rep 2013 Jun 7;2013 doi: 10.1136/bcr-2013-009037. PMID: 23749857Free PMC Article

Therapy

Li R, Li J, Chen S, Xiao B, Liu L, Zhu N
Biomed Res Int 2021;2021:7739628. Epub 2021 Nov 17 doi: 10.1155/2021/7739628. PMID: 34840980Free PMC Article
Gutiérrez-Cárdenas J, Wang Z
Interdiscip Sci 2021 Dec;13(4):572-581. Epub 2021 Jun 21 doi: 10.1007/s12539-021-00451-6. PMID: 34152557
Dianatinasab M, Rezaian M, HaghighatNezad E, Bagheri-Hosseinabadi Z, Amanat S, Rezaeian S, Masoudi A, Ghiasvand R
Clin Breast Cancer 2020 Aug;20(4):e516-e528. Epub 2020 Mar 28 doi: 10.1016/j.clbc.2020.03.007. PMID: 32362500
Binesh F, Vahedian H, Akhavan A, Hakiminia M
BMJ Case Rep 2013 Jun 7;2013 doi: 10.1136/bcr-2013-009037. PMID: 23749857Free PMC Article
Peihong S, Perry F
Ethiop Med J 2007 Jan;45(1):79-83. PMID: 17642161

Prognosis

Brown J, Scardo S, Method M, Schlauch D, Misch A, Picard S, Hamilton E, Jones S, Burris H, Spigel D
BMC Cancer 2022 May 6;22(1):502. doi: 10.1186/s12885-022-09557-6. PMID: 35524219Free PMC Article
Hottat NA, Badr DA, Lecomte S, Besse-Hammer T, Jani JC, Cannie MM
Eur Radiol 2022 Jun;32(6):4067-4078. Epub 2022 Jan 11 doi: 10.1007/s00330-021-08462-z. PMID: 35015127
Tariq MU, Idress R, Qureshi MB, Kayani N
Breast J 2020 Feb;26(2):211-215. Epub 2019 Sep 18 doi: 10.1111/tbj.13521. PMID: 31532003
Tormo V, Andreu FJ
Clin Transl Oncol 2009 Dec;11(12):854-5. doi: 10.1007/s12094-009-0456-1. PMID: 20045794
Peihong S, Perry F
Ethiop Med J 2007 Jan;45(1):79-83. PMID: 17642161

Clinical prediction guides

Brown J, Scardo S, Method M, Schlauch D, Misch A, Picard S, Hamilton E, Jones S, Burris H, Spigel D
BMC Cancer 2022 May 6;22(1):502. doi: 10.1186/s12885-022-09557-6. PMID: 35524219Free PMC Article
Ficarra S, Thomas E, Bianco A, Gentile A, Thaller P, Grassadonio F, Papakonstantinou S, Schulz T, Olson N, Martin A, Wagner C, Nordström A, Hofmann H
Breast Cancer 2022 May;29(3):402-418. Epub 2022 Mar 12 doi: 10.1007/s12282-022-01347-z. PMID: 35278203Free PMC Article
Sun C, Lu Q, Zhang X, Zhang Y, Jia S, Wang J, Zhu H, He W, Zhang Z
Medicine (Baltimore) 2021 Aug 27;100(34):e26970. doi: 10.1097/MD.0000000000026970. PMID: 34449464Free PMC Article
Dianatinasab M, Rezaian M, HaghighatNezad E, Bagheri-Hosseinabadi Z, Amanat S, Rezaeian S, Masoudi A, Ghiasvand R
Clin Breast Cancer 2020 Aug;20(4):e516-e528. Epub 2020 Mar 28 doi: 10.1016/j.clbc.2020.03.007. PMID: 32362500
Carlos L Lopes-Júnior, Cruz LA, Leopoldo VC, Campos FR, Almeida AM, Silveira RC
Rev Lat Am Enfermagem 2016 Aug 15;24:e2762. doi: 10.1590/1518-8345.0647.2762. PMID: 27533271Free PMC Article

Recent systematic reviews

Wintraecken VM, Vulik S, de Wild S, Dirksen C, Koppert LB, de Vries J, Smidt ML
BMC Cancer 2022 Apr 19;22(1):426. doi: 10.1186/s12885-022-09408-4. PMID: 35439953Free PMC Article
Ficarra S, Thomas E, Bianco A, Gentile A, Thaller P, Grassadonio F, Papakonstantinou S, Schulz T, Olson N, Martin A, Wagner C, Nordström A, Hofmann H
Breast Cancer 2022 May;29(3):402-418. Epub 2022 Mar 12 doi: 10.1007/s12282-022-01347-z. PMID: 35278203Free PMC Article
Wang S, Yang T, Qiang W, Shen A, Zhao Z, Yang H, Liu X
Support Care Cancer 2022 Apr;30(4):2993-3006. Epub 2021 Oct 25 doi: 10.1007/s00520-021-06641-8. PMID: 34694496
Aarts BM, Muñoz FMG, Wildiers H, Dezentjé VO, Baetens TR, Schats W, Lopez-Yurda M, Dresen RC, Wit-van der Veen BJ, Deroose CM, Maleux G, Beets-Tan RGH, Klompenhouwer EG
Cardiovasc Intervent Radiol 2021 Dec;44(12):1868-1882. Epub 2021 Jul 28 doi: 10.1007/s00270-021-02906-1. PMID: 34322751
Dianatinasab M, Rezaian M, HaghighatNezad E, Bagheri-Hosseinabadi Z, Amanat S, Rezaeian S, Masoudi A, Ghiasvand R
Clin Breast Cancer 2020 Aug;20(4):e516-e528. Epub 2020 Mar 28 doi: 10.1016/j.clbc.2020.03.007. PMID: 32362500

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