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Primary Malignant Neoplasm

MedGen UID:
227011
Concept ID:
C1306459
Neoplastic Process
Synonyms: Cancer; Cancer morphology; Malignancy; Malignant neoplasm; Malignant neoplasm, primary; Malignant tumor morphology; Neoplasm, malignant; Neoplasm, malignant (primary); Primary malignant neoplasm; Tumor, malignant; Unclassified tumor, malignant
SNOMED CT: Primary malignant neoplasm (372087000); Malignant tumor morphology (86049000); Cancer morphology (86049000); Neoplasm, malignant (86049000); Malignancy (86049000); Cancer (86049000); Unclassified tumor, malignant (86049000); Tumor, malignant (86049000); Malignant neoplasm (86049000); Malignant neoplasm, primary (86049000); Neoplasm, malignant (primary) (86049000)

Definition

A malignant tumor at the original site of growth. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPrimary Malignant Neoplasm

Recent clinical studies

Etiology

Naik A, Bhandari V, Saadvik RY, Gupta KL, Kausar M, Batra M
J Cancer Res Ther 2018 Jul-Sep;14(5):999-1004. doi: 10.4103/0973-1482.183560. PMID: 30197338
Adjei Boakye E, Buchanan P, Hinyard L, Osazuwa-Peters N, Schootman M, Piccirillo JF
JAMA Otolaryngol Head Neck Surg 2018 Aug 1;144(8):727-737. doi: 10.1001/jamaoto.2018.0993. PMID: 30027284Free PMC Article
Esposito ED, Bevilacqua L, Guadagno MT
J Surg Oncol 2000 May;74(1):83-6. doi: 10.1002/1096-9098(200005)74:1<83::aid-jso18>3.0.co;2-q. PMID: 10861616
Ampil FL
Obstet Gynecol 1985 Dec;66(6):799-804. PMID: 3934611
Ray P, Guinan P, Sharifi R, Mouli K, Shaw M
Prostate 1983;4(5):513-22. doi: 10.1002/pros.2990040510. PMID: 6684282

Diagnosis

Li YJ, Li YW, Cui GH, Li SH, Deng YW, Lu D
Anticancer Drugs 2022 Aug 1;33(7):686-690. Epub 2022 Jun 21 doi: 10.1097/CAD.0000000000001293. PMID: 35324515
Danial D, Youssef ED, Maryam BM, Mohammad A, Moein BM, Liliane D
Can J Gastroenterol Hepatol 2022;2022:3582443. Epub 2022 Feb 16 doi: 10.1155/2022/3582443. PMID: 35223684Free PMC Article
Naik A, Bhandari V, Saadvik RY, Gupta KL, Kausar M, Batra M
J Cancer Res Ther 2018 Jul-Sep;14(5):999-1004. doi: 10.4103/0973-1482.183560. PMID: 30197338
Adjei Boakye E, Buchanan P, Hinyard L, Osazuwa-Peters N, Schootman M, Piccirillo JF
JAMA Otolaryngol Head Neck Surg 2018 Aug 1;144(8):727-737. doi: 10.1001/jamaoto.2018.0993. PMID: 30027284Free PMC Article
Ampil FL
Obstet Gynecol 1985 Dec;66(6):799-804. PMID: 3934611

Therapy

Schmidt AL, Tucker MD, Bakouny Z, Labaki C, Hsu CY, Shyr Y, Armstrong AJ, Beer TM, Bijjula RR, Bilen MA, Connell CF, Dawsey SJ, Faller B, Gao X, Gartrell BA, Gill D, Gulati S, Halabi S, Hwang C, Joshi M, Khaki AR, Menon H, Morris MJ, Puc M, Russell KB, Shah NJ, Sharifi N, Shaya J, Schweizer MT, Steinharter J, Wulff-Burchfield EM, Xu W, Zhu J, Mishra S, Grivas P, Rini BI, Warner JL, Zhang T, Choueiri TK, Gupta S, McKay RR
JAMA Netw Open 2021 Nov 1;4(11):e2134330. doi: 10.1001/jamanetworkopen.2021.34330. PMID: 34767021Free PMC Article
Buskaran K, Hussein MZ, Moklas MAM, Masarudin MJ, Fakurazi S
Int J Mol Sci 2021 May 28;22(11) doi: 10.3390/ijms22115786. PMID: 34071389Free PMC Article
Gessler DJ, Ferreira C, Dusenbery K, Chen CC
Future Oncol 2020 Oct;16(30):2445-2455. Epub 2020 Jul 3 doi: 10.2217/fon-2020-0558. PMID: 32618209
Naik A, Bhandari V, Saadvik RY, Gupta KL, Kausar M, Batra M
J Cancer Res Ther 2018 Jul-Sep;14(5):999-1004. doi: 10.4103/0973-1482.183560. PMID: 30197338
Malone H, Yang J, Hershman DL, Wright JD, Bruce JN, Neugut AI
World Neurosurg 2015 Oct;84(4):1084-9. Epub 2015 May 22 doi: 10.1016/j.wneu.2015.05.025. PMID: 26008141

Prognosis

Kalinathan L, Kathavarayan RS, Kanmani M, Dinakaran N
Histol Histopathol 2020 Oct;35(10):1115-1123. Epub 2020 Jul 21 doi: 10.14670/HH-18-240. PMID: 32691405
Gessler DJ, Ferreira C, Dusenbery K, Chen CC
Future Oncol 2020 Oct;16(30):2445-2455. Epub 2020 Jul 3 doi: 10.2217/fon-2020-0558. PMID: 32618209
Adjei Boakye E, Buchanan P, Hinyard L, Osazuwa-Peters N, Schootman M, Piccirillo JF
JAMA Otolaryngol Head Neck Surg 2018 Aug 1;144(8):727-737. doi: 10.1001/jamaoto.2018.0993. PMID: 30027284Free PMC Article
Malone H, Yang J, Hershman DL, Wright JD, Bruce JN, Neugut AI
World Neurosurg 2015 Oct;84(4):1084-9. Epub 2015 May 22 doi: 10.1016/j.wneu.2015.05.025. PMID: 26008141
Esposito ED, Bevilacqua L, Guadagno MT
J Surg Oncol 2000 May;74(1):83-6. doi: 10.1002/1096-9098(200005)74:1<83::aid-jso18>3.0.co;2-q. PMID: 10861616

Clinical prediction guides

Schmidt AL, Tucker MD, Bakouny Z, Labaki C, Hsu CY, Shyr Y, Armstrong AJ, Beer TM, Bijjula RR, Bilen MA, Connell CF, Dawsey SJ, Faller B, Gao X, Gartrell BA, Gill D, Gulati S, Halabi S, Hwang C, Joshi M, Khaki AR, Menon H, Morris MJ, Puc M, Russell KB, Shah NJ, Sharifi N, Shaya J, Schweizer MT, Steinharter J, Wulff-Burchfield EM, Xu W, Zhu J, Mishra S, Grivas P, Rini BI, Warner JL, Zhang T, Choueiri TK, Gupta S, McKay RR
JAMA Netw Open 2021 Nov 1;4(11):e2134330. doi: 10.1001/jamanetworkopen.2021.34330. PMID: 34767021Free PMC Article
Naik A, Bhandari V, Saadvik RY, Gupta KL, Kausar M, Batra M
J Cancer Res Ther 2018 Jul-Sep;14(5):999-1004. doi: 10.4103/0973-1482.183560. PMID: 30197338
Adjei Boakye E, Buchanan P, Hinyard L, Osazuwa-Peters N, Schootman M, Piccirillo JF
JAMA Otolaryngol Head Neck Surg 2018 Aug 1;144(8):727-737. doi: 10.1001/jamaoto.2018.0993. PMID: 30027284Free PMC Article
Esposito ED, Bevilacqua L, Guadagno MT
J Surg Oncol 2000 May;74(1):83-6. doi: 10.1002/1096-9098(200005)74:1<83::aid-jso18>3.0.co;2-q. PMID: 10861616
Ampil FL
Obstet Gynecol 1985 Dec;66(6):799-804. PMID: 3934611

Recent systematic reviews

Paul Olson TJ, Pinkerton C, Brasel KJ, Schwarze ML
JAMA Surg 2014 Apr;149(4):383-92. doi: 10.1001/jamasurg.2013.4059. PMID: 24477929Free PMC Article

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