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Mean blood pressure

MedGen UID:
98447
•Concept ID:
C0428886
•
Finding
Synonyms: Arterial Pressure, Mean; Arterial Pressures, Mean; Mean Arterial Pressure; Mean Arterial Pressures; Pressure, Mean Arterial; Pressures, Mean Arterial
SNOMED CT: MAP - Mean arterial pressure (6797001); MBP - Mean blood pressure (6797001); Mean blood pressure (6797001)

Definition

A blood pressure that refers to the average over a cardiac cycle [from SNOMEDCT_US]

Recent clinical studies

Etiology

Impact of mean blood pressure and blood pressure variability after diagnosis of mild cognitive impairment and risk of dementia.
de Havenon A, Muddasani V, Anadani M, Prabhakaran S
J Clin Hypertens (Greenwich) 2021 Dec;23(12):2124-2128. Epub 2021 Dec 4 doi: 10.1111/jch.14391. PMID: 34862714Free PMC Article
The association of resting postoperative systolic, diastolic, and mean blood pressure and pulse pressure with short- and long-term mortality in patients with acute coronary syndrome undergoing primary percutaneous coronary intervention.
Zhu QL, Zhou J, Shan PR, Zhou CZ, Xu PF, Huang WJ
Minerva Cardiol Angiol 2021 Jun;69(3):280-287. Epub 2020 Jul 8 doi: 10.23736/S2724-5683.20.05120-8. PMID: 32643894
Quantification of effects of mean blood pressure and left ventricular mass on noninvasive fast fractional flow reserve.
Zhang JM, Chandola G, Tan RS, Chai P, Teo LLS, Low R, Allen JC, Huang W, Fam JM, Chin CY, Wong ASL, Low AF, Kassab GS, Chua T, Tan SY, Lim ST, Zhong L
Am J Physiol Heart Circ Physiol 2020 Aug 1;319(2):H360-H369. Epub 2020 Jul 17 doi: 10.1152/ajpheart.00135.2020. PMID: 32678708
Differences in regional grey matter volume of the brain are related to mean blood pressure and muscle sympathetic nerve activity in normotensive humans.
Kobuch S, Fatouleh RH, Macefield JM, Henderson LA, Macefield VG
J Hypertens 2020 Feb;38(2):303-313. doi: 10.1097/HJH.0000000000002243. PMID: 31568059
Soluble endothelial protein C is associated with blood pressure variability and salt consumption but not mean blood pressure in patients with newly diagnosed primary hypertension.
Özkan G, Kara SP, Fidan Ç, Güzel S, Ulusoy Ş
Clin Exp Hypertens 2019;41(4):353-358. Epub 2018 May 31 doi: 10.1080/10641963.2018.1481425. PMID: 29851520

Diagnosis

Association of an Automated Blood Pressure Measurement Quality Improvement Program With Terminal Digit Preference and Recorded Mean Blood Pressure in 11 Clinics.
Kottke TE, Anderson JP, Zillhardt JD, Sperl-Hillen JM, O'Connor PJ, Green BB, Williams RA, Averbeck BM, Stiffman MN, Beran M, Rakotz M, Margolis KL
JAMA Netw Open 2022 Aug 1;5(8):e2229098. doi: 10.1001/jamanetworkopen.2022.29098. PMID: 36044216Free PMC Article
Impact of mean blood pressure and blood pressure variability after diagnosis of mild cognitive impairment and risk of dementia.
de Havenon A, Muddasani V, Anadani M, Prabhakaran S
J Clin Hypertens (Greenwich) 2021 Dec;23(12):2124-2128. Epub 2021 Dec 4 doi: 10.1111/jch.14391. PMID: 34862714Free PMC Article
Adverse Outcomes Associated With Higher Mean Blood Pressure and Greater Blood Pressure Variability Immediately After Successful Embolectomy in Those With Acute Ischemic Stroke, and the Influence of Pretreatment Collateral Circulation Status.
Liu D, Nie X, Pan Y, Yan H, Pu Y, Wei Y, Cai Y, Ding Y, Lu Q, Zhang Z, Gu W, Hou X, Yang Z, Wen M, Wang P, Ma G, Ma N, Miao Z, Leng X, Yan B, Davis SM, Wang Y, Liu L
J Am Heart Assoc 2021 Feb;10(5):e019350. Epub 2021 Feb 26 doi: 10.1161/JAHA.120.019350. PMID: 33634704Free PMC Article
Quantification of effects of mean blood pressure and left ventricular mass on noninvasive fast fractional flow reserve.
Zhang JM, Chandola G, Tan RS, Chai P, Teo LLS, Low R, Allen JC, Huang W, Fam JM, Chin CY, Wong ASL, Low AF, Kassab GS, Chua T, Tan SY, Lim ST, Zhong L
Am J Physiol Heart Circ Physiol 2020 Aug 1;319(2):H360-H369. Epub 2020 Jul 17 doi: 10.1152/ajpheart.00135.2020. PMID: 32678708
Soluble endothelial protein C is associated with blood pressure variability and salt consumption but not mean blood pressure in patients with newly diagnosed primary hypertension.
Özkan G, Kara SP, Fidan Ç, Güzel S, Ulusoy Ş
Clin Exp Hypertens 2019;41(4):353-358. Epub 2018 May 31 doi: 10.1080/10641963.2018.1481425. PMID: 29851520

Therapy

Association of an Automated Blood Pressure Measurement Quality Improvement Program With Terminal Digit Preference and Recorded Mean Blood Pressure in 11 Clinics.
Kottke TE, Anderson JP, Zillhardt JD, Sperl-Hillen JM, O'Connor PJ, Green BB, Williams RA, Averbeck BM, Stiffman MN, Beran M, Rakotz M, Margolis KL
JAMA Netw Open 2022 Aug 1;5(8):e2229098. doi: 10.1001/jamanetworkopen.2022.29098. PMID: 36044216Free PMC Article
Adverse Outcomes Associated With Higher Mean Blood Pressure and Greater Blood Pressure Variability Immediately After Successful Embolectomy in Those With Acute Ischemic Stroke, and the Influence of Pretreatment Collateral Circulation Status.
Liu D, Nie X, Pan Y, Yan H, Pu Y, Wei Y, Cai Y, Ding Y, Lu Q, Zhang Z, Gu W, Hou X, Yang Z, Wen M, Wang P, Ma G, Ma N, Miao Z, Leng X, Yan B, Davis SM, Wang Y, Liu L
J Am Heart Assoc 2021 Feb;10(5):e019350. Epub 2021 Feb 26 doi: 10.1161/JAHA.120.019350. PMID: 33634704Free PMC Article
Mean Blood Pressure of the General Population with the Mean of Three Measurements Versus the Mean of the Second and Third Measurements. Ricarto Study.
Villarín Castro A, Segura Fragoso A, Alonso Moreno FJ, Sánchez Pérez M, Rodríguez Padial L, Rodríguez Roca GC
High Blood Press Cardiovasc Prev 2019 Oct;26(5):391-397. Epub 2019 Aug 26 doi: 10.1007/s40292-019-00338-0. PMID: 31452090
The effect of hormone therapy on mean blood pressure and visit-to-visit blood pressure variability in postmenopausal women: results from the Women's Health Initiative randomized controlled trials.
Shimbo D, Wang L, Lamonte MJ, Allison M, Wellenius GA, Bavry AA, Martin LW, Aragaki A, Newman JD, Swica Y, Rossouw JE, Manson JE, Wassertheil-Smoller S
J Hypertens 2014 Oct;32(10):2071-81; discussion 2081. doi: 10.1097/HJH.0000000000000287. PMID: 24991872Free PMC Article
Both morning and evening dosing of nebivolol reduces trough mean blood pressure surge in hypertensive patients.
Acelajado MC, Pisoni R, Dudenbostel T, Oparil S, Calhoun DA, Glasser SP
J Am Soc Hypertens 2012 Jan-Feb;6(1):66-72. Epub 2011 Oct 22 doi: 10.1016/j.jash.2011.09.001. PMID: 22024668Free PMC Article

Prognosis

Adverse Outcomes Associated With Higher Mean Blood Pressure and Greater Blood Pressure Variability Immediately After Successful Embolectomy in Those With Acute Ischemic Stroke, and the Influence of Pretreatment Collateral Circulation Status.
Liu D, Nie X, Pan Y, Yan H, Pu Y, Wei Y, Cai Y, Ding Y, Lu Q, Zhang Z, Gu W, Hou X, Yang Z, Wen M, Wang P, Ma G, Ma N, Miao Z, Leng X, Yan B, Davis SM, Wang Y, Liu L
J Am Heart Assoc 2021 Feb;10(5):e019350. Epub 2021 Feb 26 doi: 10.1161/JAHA.120.019350. PMID: 33634704Free PMC Article
The association of resting postoperative systolic, diastolic, and mean blood pressure and pulse pressure with short- and long-term mortality in patients with acute coronary syndrome undergoing primary percutaneous coronary intervention.
Zhu QL, Zhou J, Shan PR, Zhou CZ, Xu PF, Huang WJ
Minerva Cardiol Angiol 2021 Jun;69(3):280-287. Epub 2020 Jul 8 doi: 10.23736/S2724-5683.20.05120-8. PMID: 32643894
Quantification of effects of mean blood pressure and left ventricular mass on noninvasive fast fractional flow reserve.
Zhang JM, Chandola G, Tan RS, Chai P, Teo LLS, Low R, Allen JC, Huang W, Fam JM, Chin CY, Wong ASL, Low AF, Kassab GS, Chua T, Tan SY, Lim ST, Zhong L
Am J Physiol Heart Circ Physiol 2020 Aug 1;319(2):H360-H369. Epub 2020 Jul 17 doi: 10.1152/ajpheart.00135.2020. PMID: 32678708
Differences in regional grey matter volume of the brain are related to mean blood pressure and muscle sympathetic nerve activity in normotensive humans.
Kobuch S, Fatouleh RH, Macefield JM, Henderson LA, Macefield VG
J Hypertens 2020 Feb;38(2):303-313. doi: 10.1097/HJH.0000000000002243. PMID: 31568059
Mean Blood Pressure of the General Population with the Mean of Three Measurements Versus the Mean of the Second and Third Measurements. Ricarto Study.
Villarín Castro A, Segura Fragoso A, Alonso Moreno FJ, Sánchez Pérez M, Rodríguez Padial L, Rodríguez Roca GC
High Blood Press Cardiovasc Prev 2019 Oct;26(5):391-397. Epub 2019 Aug 26 doi: 10.1007/s40292-019-00338-0. PMID: 31452090

Clinical prediction guides

Impact of mean blood pressure and blood pressure variability after diagnosis of mild cognitive impairment and risk of dementia.
de Havenon A, Muddasani V, Anadani M, Prabhakaran S
J Clin Hypertens (Greenwich) 2021 Dec;23(12):2124-2128. Epub 2021 Dec 4 doi: 10.1111/jch.14391. PMID: 34862714Free PMC Article
Adverse Outcomes Associated With Higher Mean Blood Pressure and Greater Blood Pressure Variability Immediately After Successful Embolectomy in Those With Acute Ischemic Stroke, and the Influence of Pretreatment Collateral Circulation Status.
Liu D, Nie X, Pan Y, Yan H, Pu Y, Wei Y, Cai Y, Ding Y, Lu Q, Zhang Z, Gu W, Hou X, Yang Z, Wen M, Wang P, Ma G, Ma N, Miao Z, Leng X, Yan B, Davis SM, Wang Y, Liu L
J Am Heart Assoc 2021 Feb;10(5):e019350. Epub 2021 Feb 26 doi: 10.1161/JAHA.120.019350. PMID: 33634704Free PMC Article
Quantification of effects of mean blood pressure and left ventricular mass on noninvasive fast fractional flow reserve.
Zhang JM, Chandola G, Tan RS, Chai P, Teo LLS, Low R, Allen JC, Huang W, Fam JM, Chin CY, Wong ASL, Low AF, Kassab GS, Chua T, Tan SY, Lim ST, Zhong L
Am J Physiol Heart Circ Physiol 2020 Aug 1;319(2):H360-H369. Epub 2020 Jul 17 doi: 10.1152/ajpheart.00135.2020. PMID: 32678708
Differences in regional grey matter volume of the brain are related to mean blood pressure and muscle sympathetic nerve activity in normotensive humans.
Kobuch S, Fatouleh RH, Macefield JM, Henderson LA, Macefield VG
J Hypertens 2020 Feb;38(2):303-313. doi: 10.1097/HJH.0000000000002243. PMID: 31568059
Mean Blood Pressure of the General Population with the Mean of Three Measurements Versus the Mean of the Second and Third Measurements. Ricarto Study.
Villarín Castro A, Segura Fragoso A, Alonso Moreno FJ, Sánchez Pérez M, Rodríguez Padial L, Rodríguez Roca GC
High Blood Press Cardiovasc Prev 2019 Oct;26(5):391-397. Epub 2019 Aug 26 doi: 10.1007/s40292-019-00338-0. PMID: 31452090

Recent systematic reviews

To compare different non-surgical treatment modalities on treatment of obstructive sleep apnea: A systematic review and meta-analysis.
Vimal J, Dutt P, Singh N, Singh BP, Chand P, Jurel S
J Indian Prosthodont Soc 2022 Oct-Dec;22(4):314-327. doi: 10.4103/jips.jips_261_22. PMID: 36511065Free PMC Article
Evaluation of the Safety and Efficacy of Dual Therapy Perindopril/Amlodipine in the Management of Hypertension. A Systematic Review and Meta-Analysis.
Mostafa S, Shabana H, Khalil F, Mancy IME, Zedan HA, Elmoursi A, Ramadan IG, Mohamed SED, Kassem A, Kamel IS
High Blood Press Cardiovasc Prev 2022 Nov;29(6):565-576. Epub 2022 Oct 26 doi: 10.1007/s40292-022-00544-3. PMID: 36287359
Feasibility of sleep extension and its effect on cardiometabolic parameters in free-living settings: a systematic review and meta-analysis of experimental studies.
Zhu B, Yin Y, Shi C, Chaiard J, Park CG, Chen X, Izci-Balserak B
Eur J Cardiovasc Nurs 2022 Jan 11;21(1):9-25. doi: 10.1093/eurjcn/zvab055. PMID: 34279625
Short-term efficacy of umbilical cord milking in preterm infants: systematic review and meta-analysis.
Barboza JJ, Albitres-Flores L, Rivera-Meza M, Rodriguez-Huapaya J, Caballero-Alvarado J, Pasupuleti V, Hernandez AV
Pediatr Res 2021 Jan;89(1):22-30. Epub 2020 Apr 21 doi: 10.1038/s41390-020-0902-x. PMID: 32316030
Trends in hypertension prevalence (1990-2005) and mean blood pressure (1975-2005) in Portugal: a systematic review.
Pereira M, Carreira H, Vales C, Rocha V, Azevedo A, Lunet N
Blood Press 2012 Aug;21(4):220-6. Epub 2012 Mar 27 doi: 10.3109/08037051.2012.666380. PMID: 22452311

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