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Acute myocardial infarction

MedGen UID:
57611
Concept ID:
C0155626
Disease or Syndrome
Synonyms: Acute Myocardial Infarction; acute myocardial infarction; acute myocardial infarction (disease); AMI - Acute myocardial infarction; myocardial infarction (disease), acute
SNOMED CT: AMI - Acute myocardial infarction (57054005); Acute myocardial infarction (57054005)
 
Monarch Initiative: MONDO:0004781

Definition

Necrosis of the myocardium, as a result of interruption of the blood supply to the area. It is characterized by a severe and rapid onset of symptoms that may include chest pain, often radiating to the left arm and left side of the neck, dyspnea, sweating, and palpitations. [from NCI]

Recent clinical studies

Etiology

Katsoularis I, Fonseca-Rodríguez O, Farrington P, Lindmark K, Fors Connolly AM
Lancet 2021 Aug 14;398(10300):599-607. Epub 2021 Jul 29 doi: 10.1016/S0140-6736(21)00896-5. PMID: 34332652Free PMC Article
Lei Y, Wang Y, Song Y, Cai Y
Ann Palliat Med 2021 Jun;10(6):7107-7113. doi: 10.21037/apm-21-1193. PMID: 34237990
Elbadawi A, Elgendy IY, Omer M, Abdelazeem M, Nambi V, Krittanawong C, Hira RS, Tamis-Holland J, Ballantyne C, Jneid H
Am J Med 2021 Aug;134(8):992-1001.e4. Epub 2021 Apr 16 doi: 10.1016/j.amjmed.2021.03.013. PMID: 33872584
Yang J, Wang L, Sun T, Guo Q, Liu F, Zhou Y
Perfusion 2020 Jul;35(5):384-392. Epub 2019 Nov 1 doi: 10.1177/0267659119883996. PMID: 31674878
Sulo G, Sulo E, Jørgensen T, Linnenberg A, Prescott E, Tell GS, Osler M
Scand J Public Health 2020 May;48(3):294-302. Epub 2019 Feb 28 doi: 10.1177/1403494819829333. PMID: 30813840

Diagnosis

Lei Y, Wang Y, Song Y, Cai Y
Ann Palliat Med 2021 Jun;10(6):7107-7113. doi: 10.21037/apm-21-1193. PMID: 34237990
Meyer MR, Radovanovic D, Pedrazzini G, Rickli H, Roffi M, Rosemann T, Eberli FR, Kurz DJ
Eur Heart J Acute Cardiovasc Care 2020 Dec;9(8):848-856. Epub 2020 Feb 7 doi: 10.1177/2048872620905101. PMID: 32030999
Sulo G, Sulo E, Jørgensen T, Linnenberg A, Prescott E, Tell GS, Osler M
Scand J Public Health 2020 May;48(3):294-302. Epub 2019 Feb 28 doi: 10.1177/1403494819829333. PMID: 30813840
Arslan M, Dedic A, Boersma E, Dubois EA
Eur Heart J Acute Cardiovasc Care 2020 Feb;9(1):14-22. Epub 2019 Jan 8 doi: 10.1177/2048872618819421. PMID: 30618277Free PMC Article
Vejpongsa P, Kitkungvan D, Madjid M, Charitakis K, Anderson HV, Arain S, Balan P, Smalling RW, Dhoble A
Am J Med 2019 Oct;132(10):1173-1181. Epub 2019 May 28 doi: 10.1016/j.amjmed.2019.05.002. PMID: 31145880

Therapy

Yang Y, Gao S, Fang Q, Zhu M
Medicine (Baltimore) 2021 Jan 22;100(3):e24246. doi: 10.1097/MD.0000000000024246. PMID: 33546045Free PMC Article
Yang Y, Cao Y, Huang W, Jiang W
Ann Palliat Med 2021 Jun;10(6):7028-7032. Epub 2020 Dec 15 doi: 10.21037/apm-20-962. PMID: 33353348
Andell P, James S, Östlund O, Yndigegn T, Sparv D, Pernow J, Jernberg T, Lindahl B, Herlitz J, Erlinge D, Hofmann R
Eur Heart J Acute Cardiovasc Care 2020 Dec;9(8):984-992. Epub 2019 May 13 doi: 10.1177/2048872619848978. PMID: 31081342
Safi S, Sethi NJ, Nielsen EE, Feinberg J, Jakobsen JC, Gluud C
Cochrane Database Syst Rev 2019 Dec 17;12:CD012484. doi: 10.1002/14651858.CD012484.pub2. PMID: 31845756Free PMC Article
Rubinfeld GD, Smilowitz NR, Berger JS, Newman JD
Am J Med 2019 Aug;132(8):942-948.e5. Epub 2019 Apr 27 doi: 10.1016/j.amjmed.2019.04.003. PMID: 31034804Free PMC Article

Prognosis

Katsoularis I, Fonseca-Rodríguez O, Farrington P, Lindmark K, Fors Connolly AM
Lancet 2021 Aug 14;398(10300):599-607. Epub 2021 Jul 29 doi: 10.1016/S0140-6736(21)00896-5. PMID: 34332652Free PMC Article
Lei Y, Wang Y, Song Y, Cai Y
Ann Palliat Med 2021 Jun;10(6):7107-7113. doi: 10.21037/apm-21-1193. PMID: 34237990
Elbadawi A, Ahmed HMA, Elgendy IY, Omer MA, Ogunbayo GO, Abohamad S, Paniagua D, Jneid H
Am J Med 2020 Oct;133(10):1168-1179.e4. Epub 2020 Apr 10 doi: 10.1016/j.amjmed.2020.02.039. PMID: 32278845
Yang J, Wang L, Sun T, Guo Q, Liu F, Zhou Y
Perfusion 2020 Jul;35(5):384-392. Epub 2019 Nov 1 doi: 10.1177/0267659119883996. PMID: 31674878
Sulo G, Sulo E, Jørgensen T, Linnenberg A, Prescott E, Tell GS, Osler M
Scand J Public Health 2020 May;48(3):294-302. Epub 2019 Feb 28 doi: 10.1177/1403494819829333. PMID: 30813840

Clinical prediction guides

Elbadawi A, Elgendy IY, Omer M, Abdelazeem M, Nambi V, Krittanawong C, Hira RS, Tamis-Holland J, Ballantyne C, Jneid H
Am J Med 2021 Aug;134(8):992-1001.e4. Epub 2021 Apr 16 doi: 10.1016/j.amjmed.2021.03.013. PMID: 33872584
Yang Y, Gao S, Fang Q, Zhu M
Medicine (Baltimore) 2021 Jan 22;100(3):e24246. doi: 10.1097/MD.0000000000024246. PMID: 33546045Free PMC Article
Elbadawi A, Ahmed HMA, Elgendy IY, Omer MA, Ogunbayo GO, Abohamad S, Paniagua D, Jneid H
Am J Med 2020 Oct;133(10):1168-1179.e4. Epub 2020 Apr 10 doi: 10.1016/j.amjmed.2020.02.039. PMID: 32278845
Yang J, Wang L, Sun T, Guo Q, Liu F, Zhou Y
Perfusion 2020 Jul;35(5):384-392. Epub 2019 Nov 1 doi: 10.1177/0267659119883996. PMID: 31674878
Vejpongsa P, Kitkungvan D, Madjid M, Charitakis K, Anderson HV, Arain S, Balan P, Smalling RW, Dhoble A
Am J Med 2019 Oct;132(10):1173-1181. Epub 2019 May 28 doi: 10.1016/j.amjmed.2019.05.002. PMID: 31145880

Recent systematic reviews

Arslan M, Dedic A, Boersma E, Dubois EA
Eur Heart J Acute Cardiovasc Care 2020 Feb;9(1):14-22. Epub 2019 Jan 8 doi: 10.1177/2048872618819421. PMID: 30618277Free PMC Article
Safi S, Sethi NJ, Nielsen EE, Feinberg J, Jakobsen JC, Gluud C
Cochrane Database Syst Rev 2019 Dec 17;12:CD012484. doi: 10.1002/14651858.CD012484.pub2. PMID: 31845756Free PMC Article
de Waha S, Jobs A, Eitel I, Pöss J, Stiermaier T, Meyer-Saraei R, Fuernau G, Zeymer U, Desch S, Thiele H
Eur Heart J Acute Cardiovasc Care 2018 Feb;7(1):28-37. Epub 2017 Jul 13 doi: 10.1177/2048872617719640. PMID: 28703046
Bally M, Dendukuri N, Rich B, Nadeau L, Helin-Salmivaara A, Garbe E, Brophy JM
BMJ 2017 May 9;357:j1909. doi: 10.1136/bmj.j1909. PMID: 28487435Free PMC Article
Zhelev Z, Hyde C, Youngman E, Rogers M, Fleming S, Slade T, Coelho H, Jones-Hughes T, Nikolaou V
BMJ 2015 Jan 20;350:h15. doi: 10.1136/bmj.h15. PMID: 25646632Free PMC Article

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