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Seasonal affective disorder(SAD)

MedGen UID:
38984
Concept ID:
C0085159
Mental or Behavioral Dysfunction
Synonym: SAD
SNOMED CT: Seasonal affective disorder (247803002); SAD - Seasonal affective disorder (247803002)
 
Monarch Initiative: MONDO:0000694
OMIM®: 608516

Definition

A syndrome characterized by depressions that recur annually at the same time each year, usually during the winter months. Other symptoms include anxiety, irritability, decreased energy, increased appetite (carbohydrate cravings), increased duration of sleep, and weight gain. sad (seasonal affective disorder) can be treated by daily exposure to bright artificial lights (phototherapy), during the season of recurrence. [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSeasonal affective disorder

Professional guidelines

PubMed

Swainson J, Reeson M, Malik U, Stefanuk I, Cummins M, Sivapalan S
J Affect Disord 2023 Apr 14;327:270-278. Epub 2023 Feb 3 doi: 10.1016/j.jad.2023.01.094. PMID: 36738997
Pjrek E, Friedrich ME, Cambioli L, Dold M, Jäger F, Komorowski A, Lanzenberger R, Kasper S, Winkler D
Psychother Psychosom 2020;89(1):17-24. Epub 2019 Oct 1 doi: 10.1159/000502891. PMID: 31574513
Tam EM, Lam RW, Levitt AJ
Can J Psychiatry 1995 Oct;40(8):457-66. doi: 10.1177/070674379504000806. PMID: 8681269

Recent clinical studies

Etiology

Galima SV, Vogel SR, Kowalski AW
Am Fam Physician 2020 Dec 1;102(11):668-672. PMID: 33252911
Nussbaumer-Streit B, Greenblatt A, Kaminski-Hartenthaler A, Van Noord MG, Forneris CA, Morgan LC, Gaynes BN, Wipplinger J, Lux LJ, Winkler D, Gartlehner G
Cochrane Database Syst Rev 2019 Jun 17;6(6):CD011271. doi: 10.1002/14651858.CD011271.pub3. PMID: 31206585Free PMC Article
Kaminski-Hartenthaler A, Nussbaumer B, Forneris CA, Morgan LC, Gaynes BN, Sonis JH, Greenblatt A, Wipplinger J, Lux LJ, Winkler D, Van Noord MG, Hofmann J, Gartlehner G
Cochrane Database Syst Rev 2015 Nov 11;(11):CD011271. doi: 10.1002/14651858.CD011271.pub2. PMID: 26560173
Forneris CA, Nussbaumer B, Kaminski-Hartenthaler A, Morgan LC, Gaynes BN, Sonis JH, Greenblatt A, Wipplinger J, Lux LJ, Winkler D, Van Noord MG, Hofmann J, Gartlehner G
Cochrane Database Syst Rev 2015 Nov 11;(11):CD011270. doi: 10.1002/14651858.CD011270.pub2. PMID: 26560172
Nussbaumer B, Kaminski-Hartenthaler A, Forneris CA, Morgan LC, Sonis JH, Gaynes BN, Greenblatt A, Wipplinger J, Lux LJ, Winkler D, Van Noord MG, Hofmann J, Gartlehner G
Cochrane Database Syst Rev 2015 Nov 8;(11):CD011269. doi: 10.1002/14651858.CD011269.pub2. PMID: 26558494

Diagnosis

Galima SV, Vogel SR, Kowalski AW
Am Fam Physician 2020 Dec 1;102(11):668-672. PMID: 33252911
Tao L, Jiang R, Zhang K, Qian Z, Chen P, Lv Y, Yao Y
Psychiatry Res 2020 Sep;291:113247. Epub 2020 Jun 22 doi: 10.1016/j.psychres.2020.113247. PMID: 32622169
Oginska H, Oginska-Bruchal K
Chronobiol Int 2014 May;31(4):523-31. Epub 2014 Jan 7 doi: 10.3109/07420528.2013.874355. PMID: 24397301
Thaler K, Delivuk M, Chapman A, Gaynes BN, Kaminski A, Gartlehner G
Cochrane Database Syst Rev 2011 Dec 7;(12):CD008591. doi: 10.1002/14651858.CD008591.pub2. PMID: 22161433
Boyce P, Barriball E
Aust Fam Physician 2010 May;39(5):307-10. PMID: 20485718

Therapy

Do A, Li VW, Huang S, Michalak EE, Tam EM, Chakrabarty T, Yatham LN, Lam RW
Can J Psychiatry 2022 Oct;67(10):745-754. Epub 2022 May 6 doi: 10.1177/07067437221097903. PMID: 35522196Free PMC Article
Galima SV, Vogel SR, Kowalski AW
Am Fam Physician 2020 Dec 1;102(11):668-672. PMID: 33252911
Tao L, Jiang R, Zhang K, Qian Z, Chen P, Lv Y, Yao Y
Psychiatry Res 2020 Sep;291:113247. Epub 2020 Jun 22 doi: 10.1016/j.psychres.2020.113247. PMID: 32622169
Nussbaumer-Streit B, Forneris CA, Morgan LC, Van Noord MG, Gaynes BN, Greenblatt A, Wipplinger J, Lux LJ, Winkler D, Gartlehner G
Cochrane Database Syst Rev 2019 Mar 18;3(3):CD011269. doi: 10.1002/14651858.CD011269.pub3. PMID: 30883670Free PMC Article
Nussbaumer B, Kaminski-Hartenthaler A, Forneris CA, Morgan LC, Sonis JH, Gaynes BN, Greenblatt A, Wipplinger J, Lux LJ, Winkler D, Van Noord MG, Hofmann J, Gartlehner G
Cochrane Database Syst Rev 2015 Nov 8;(11):CD011269. doi: 10.1002/14651858.CD011269.pub2. PMID: 26558494

Prognosis

Nussbaumer-Streit B, Greenblatt A, Kaminski-Hartenthaler A, Van Noord MG, Forneris CA, Morgan LC, Gaynes BN, Wipplinger J, Lux LJ, Winkler D, Gartlehner G
Cochrane Database Syst Rev 2019 Jun 17;6(6):CD011271. doi: 10.1002/14651858.CD011271.pub3. PMID: 31206585Free PMC Article
Borbély AA, Daan S, Wirz-Justice A, Deboer T
J Sleep Res 2016 Apr;25(2):131-43. Epub 2016 Jan 14 doi: 10.1111/jsr.12371. PMID: 26762182
Kaminski-Hartenthaler A, Nussbaumer B, Forneris CA, Morgan LC, Gaynes BN, Sonis JH, Greenblatt A, Wipplinger J, Lux LJ, Winkler D, Van Noord MG, Hofmann J, Gartlehner G
Cochrane Database Syst Rev 2015 Nov 11;(11):CD011271. doi: 10.1002/14651858.CD011271.pub2. PMID: 26560173
Forneris CA, Nussbaumer B, Kaminski-Hartenthaler A, Morgan LC, Gaynes BN, Sonis JH, Greenblatt A, Wipplinger J, Lux LJ, Winkler D, Van Noord MG, Hofmann J, Gartlehner G
Cochrane Database Syst Rev 2015 Nov 11;(11):CD011270. doi: 10.1002/14651858.CD011270.pub2. PMID: 26560172
Nussbaumer B, Kaminski-Hartenthaler A, Forneris CA, Morgan LC, Sonis JH, Gaynes BN, Greenblatt A, Wipplinger J, Lux LJ, Winkler D, Van Noord MG, Hofmann J, Gartlehner G
Cochrane Database Syst Rev 2015 Nov 8;(11):CD011269. doi: 10.1002/14651858.CD011269.pub2. PMID: 26558494

Clinical prediction guides

Zhang R, Shokri-Kojori E, Volkow ND
Transl Psychiatry 2023 Jul 3;13(1):238. doi: 10.1038/s41398-023-02530-2. PMID: 37400428Free PMC Article
Do A, Li VW, Huang S, Michalak EE, Tam EM, Chakrabarty T, Yatham LN, Lam RW
Can J Psychiatry 2022 Oct;67(10):745-754. Epub 2022 May 6 doi: 10.1177/07067437221097903. PMID: 35522196Free PMC Article
Tao L, Jiang R, Zhang K, Qian Z, Chen P, Lv Y, Yao Y
Psychiatry Res 2020 Sep;291:113247. Epub 2020 Jun 22 doi: 10.1016/j.psychres.2020.113247. PMID: 32622169
Kaminski-Hartenthaler A, Nussbaumer B, Forneris CA, Morgan LC, Gaynes BN, Sonis JH, Greenblatt A, Wipplinger J, Lux LJ, Winkler D, Van Noord MG, Hofmann J, Gartlehner G
Cochrane Database Syst Rev 2015 Nov 11;(11):CD011271. doi: 10.1002/14651858.CD011271.pub2. PMID: 26560173
Forneris CA, Nussbaumer B, Kaminski-Hartenthaler A, Morgan LC, Gaynes BN, Sonis JH, Greenblatt A, Wipplinger J, Lux LJ, Winkler D, Van Noord MG, Hofmann J, Gartlehner G
Cochrane Database Syst Rev 2015 Nov 11;(11):CD011270. doi: 10.1002/14651858.CD011270.pub2. PMID: 26560172

Recent systematic reviews

Do A, Li VW, Huang S, Michalak EE, Tam EM, Chakrabarty T, Yatham LN, Lam RW
Can J Psychiatry 2022 Oct;67(10):745-754. Epub 2022 May 6 doi: 10.1177/07067437221097903. PMID: 35522196Free PMC Article
Nussbaumer-Streit B, Greenblatt A, Kaminski-Hartenthaler A, Van Noord MG, Forneris CA, Morgan LC, Gaynes BN, Wipplinger J, Lux LJ, Winkler D, Gartlehner G
Cochrane Database Syst Rev 2019 Jun 17;6(6):CD011271. doi: 10.1002/14651858.CD011271.pub3. PMID: 31206585Free PMC Article
Kaminski-Hartenthaler A, Nussbaumer B, Forneris CA, Morgan LC, Gaynes BN, Sonis JH, Greenblatt A, Wipplinger J, Lux LJ, Winkler D, Van Noord MG, Hofmann J, Gartlehner G
Cochrane Database Syst Rev 2015 Nov 11;(11):CD011271. doi: 10.1002/14651858.CD011271.pub2. PMID: 26560173
Forneris CA, Nussbaumer B, Kaminski-Hartenthaler A, Morgan LC, Gaynes BN, Sonis JH, Greenblatt A, Wipplinger J, Lux LJ, Winkler D, Van Noord MG, Hofmann J, Gartlehner G
Cochrane Database Syst Rev 2015 Nov 11;(11):CD011270. doi: 10.1002/14651858.CD011270.pub2. PMID: 26560172
Nussbaumer B, Kaminski-Hartenthaler A, Forneris CA, Morgan LC, Sonis JH, Gaynes BN, Greenblatt A, Wipplinger J, Lux LJ, Winkler D, Van Noord MG, Hofmann J, Gartlehner G
Cochrane Database Syst Rev 2015 Nov 8;(11):CD011269. doi: 10.1002/14651858.CD011269.pub2. PMID: 26558494

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