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Heart failure

MedGen UID:
6749
Concept ID:
C0018801
Disease or Syndrome
Synonyms: Cardiac Failure; Heart Failure
SNOMED CT: HF - Heart failure (84114007); Heart failure (84114007); Weak heart (84114007); Cardiac failure (84114007); Cardiac insufficiency (84114007)
 
Monarch Initiative: MONDO:0005252

Definition

Inability of the heart to pump blood at an adequate rate to meet tissue metabolic requirements. Clinical symptoms of heart failure include: unusual dyspnea on light exertion, recurrent dyspnea occurring in the supine position, fluid retention or rales, jugular venous distension, pulmonary edema on physical exam, or pulmonary edema on chest x-ray presumed to be cardiac dysfunction. [from NCI]

Professional guidelines

PubMed

Writing Committee Members.; ACC/AHA Joint Committee Members.
J Card Fail 2022 May;28(5):e1-e167. Epub 2022 Apr 1 doi: 10.1016/j.cardfail.2022.02.010. PMID: 35378257

External

DailyMed Drug Label, CARVEDILOL, 2019

Recent clinical studies

Etiology

Butt JH, Dewan P, Jhund PS, Anand IS, Atar D, Ge J, Desai AS, Echeverria LE, Køber L, Lam CSP, Maggioni AP, Martinez F, Packer M, Rouleau JL, Sim D, Van Veldhuisen DJ, Vrtovec B, Zannad F, Zile MR, Gong J, Lefkowitz MP, Rizkala AR, Solomon SD, McMurray JJV
J Am Coll Cardiol 2022 Sep 20;80(12):1130-1143. Epub 2022 Aug 29 doi: 10.1016/j.jacc.2022.06.037. PMID: 36050227
Butt JH, Dewan P, DeFilippis EM, Biering-Sørensen T, Docherty KF, Jhund PS, Kosiborod MN, Martinez FA, Bengtsson O, Johansen ND, Langkilde AM, Sjöstrand M, Vaduganathan M, Solomon SD, Sabatine MS, Køber L, Fiuzat M, McMurray JJV
JACC Heart Fail 2022 Aug;10(8):543-555. Epub 2022 Jun 8 doi: 10.1016/j.jchf.2022.03.009. PMID: 35902157
Razuk V, Chiarito M, Cao D, Nicolas J, Pivato CA, Camaj A, Power D, Beerkens F, Jones D, Alter A, Mathew A, Spirito A, Contreras JP, Dangas GD, Mehran R
Eur Heart J Cardiovasc Pharmacother 2022 Sep 3;8(6):557-567. doi: 10.1093/ehjcvp/pvac001. PMID: 35021205
Kapłon-Cieślicka A, Benson L, Chioncel O, Crespo-Leiro MG, Coats AJS, Anker SD, Filippatos G, Ruschitzka F, Hage C, Drożdż J, Seferovic P, Rosano GMC, Piepoli M, Mebazaa A, McDonagh T, Lainscak M, Savarese G, Ferrari R, Maggioni AP, Lund LH; on behalf of the Heart Failure Association (HFA) of the European Society of Cardiology (ESC) and the ESC Heart Failure Long-Term Registry Investigators.
Eur J Heart Fail 2022 Feb;24(2):335-350. Epub 2022 Jan 10 doi: 10.1002/ejhf.2408. PMID: 34962044
Narita K, Amiya E
Heart Fail Rev 2022 Jul;27(4):1001-1016. Epub 2021 May 4 doi: 10.1007/s10741-021-10116-7. PMID: 33945055

Diagnosis

Cowie MR, Mourilhe-Rocha R, Chang HY, Volterrani M, Ban HN, Campos de Albuquerque D, Chung E, Fonseca C, Lopatin Y, Magaña Serrano JA, Mircheva L, Moncada-Paz GA, Pagava Z, Reyes EB, Saldarriaga C, Schwartzmann P, Sim Kheng Leng D, Trivi M, Yotov YT, Zieroth S; OPTIMIZE Heart Failure Care program coordinators.
Int J Cardiol 2022 Sep 15;363:240-246. Epub 2022 Jun 22 doi: 10.1016/j.ijcard.2022.06.022. PMID: 35750302Free PMC Article
Kosiborod MN, Angermann CE, Collins SP, Teerlink JR, Ponikowski P, Biegus J, Comin-Colet J, Ferreira JP, Mentz RJ, Nassif ME, Psotka MA, Tromp J, Brueckmann M, Blatchford JP, Salsali A, Voors AA
Circulation 2022 Jul 26;146(4):279-288. Epub 2022 Apr 4 doi: 10.1161/CIRCULATIONAHA.122.059725. PMID: 35377706Free PMC Article
Leszek P, Waś D, Bartolik K, Witczak K, Kleinork A, Maruszewski B, Brukało K, Rolska-Wójcik P, Celińska-Spodar M, Hryniewiecki T, Załęska-Kocięcka M
ESC Heart Fail 2022 Jun;9(3):1553-1563. Epub 2022 Mar 24 doi: 10.1002/ehf2.13900. PMID: 35322601Free PMC Article
Jayagopal PB, Sastry SL, Nanjappa V, Abdullakutty J, Joseph J, Vaidyanathan PR, Kabra N, Manokar P, Ghanta SS, Sharma V, Mishra TK, Jathappa N, Singh V, Routray SN, Mandal S, Bhalla N, Dorairaj P, Mehta N, Kumbla D, Rane AR, Matia TK, Jain D, Rege G, Modi S, Chopra VK, Mohanan PP, Geevar Zachariah A, Ravindranath KS, Chakraborty R, Srinivas BC, Raghu TR, Manjunath CN
Int J Cardiol 2022 Jun 1;356:73-78. Epub 2022 Mar 13 doi: 10.1016/j.ijcard.2022.03.021. PMID: 35296433
Razuk V, Chiarito M, Cao D, Nicolas J, Pivato CA, Camaj A, Power D, Beerkens F, Jones D, Alter A, Mathew A, Spirito A, Contreras JP, Dangas GD, Mehran R
Eur Heart J Cardiovasc Pharmacother 2022 Sep 3;8(6):557-567. doi: 10.1093/ehjcvp/pvac001. PMID: 35021205

Therapy

Butt JH, Dewan P, Jhund PS, Anand IS, Atar D, Ge J, Desai AS, Echeverria LE, Køber L, Lam CSP, Maggioni AP, Martinez F, Packer M, Rouleau JL, Sim D, Van Veldhuisen DJ, Vrtovec B, Zannad F, Zile MR, Gong J, Lefkowitz MP, Rizkala AR, Solomon SD, McMurray JJV
J Am Coll Cardiol 2022 Sep 20;80(12):1130-1143. Epub 2022 Aug 29 doi: 10.1016/j.jacc.2022.06.037. PMID: 36050227
Butt JH, Dewan P, DeFilippis EM, Biering-Sørensen T, Docherty KF, Jhund PS, Kosiborod MN, Martinez FA, Bengtsson O, Johansen ND, Langkilde AM, Sjöstrand M, Vaduganathan M, Solomon SD, Sabatine MS, Køber L, Fiuzat M, McMurray JJV
JACC Heart Fail 2022 Aug;10(8):543-555. Epub 2022 Jun 8 doi: 10.1016/j.jchf.2022.03.009. PMID: 35902157
Kosiborod MN, Angermann CE, Collins SP, Teerlink JR, Ponikowski P, Biegus J, Comin-Colet J, Ferreira JP, Mentz RJ, Nassif ME, Psotka MA, Tromp J, Brueckmann M, Blatchford JP, Salsali A, Voors AA
Circulation 2022 Jul 26;146(4):279-288. Epub 2022 Apr 4 doi: 10.1161/CIRCULATIONAHA.122.059725. PMID: 35377706Free PMC Article
Razuk V, Chiarito M, Cao D, Nicolas J, Pivato CA, Camaj A, Power D, Beerkens F, Jones D, Alter A, Mathew A, Spirito A, Contreras JP, Dangas GD, Mehran R
Eur Heart J Cardiovasc Pharmacother 2022 Sep 3;8(6):557-567. doi: 10.1093/ehjcvp/pvac001. PMID: 35021205
Narita K, Amiya E
Heart Fail Rev 2022 Jul;27(4):1001-1016. Epub 2021 May 4 doi: 10.1007/s10741-021-10116-7. PMID: 33945055

Prognosis

Jackson AM, Benson L, Savarese G, Hage C, Jhund PS, Petrie MC, Dahlström U, McMurray JJV, Lund LH
JACC Heart Fail 2022 Jun;10(6):380-392. doi: 10.1016/j.jchf.2022.04.006. PMID: 35654522
Razaghizad A, Oulousian E, Randhawa VK, Ferreira JP, Brophy JM, Greene SJ, Guida J, Felker GM, Fudim M, Tsoukas M, Peters TM, Mavrakanas TA, Giannetti N, Ezekowitz J, Sharma A
J Am Heart Assoc 2022 May 17;11(10):e024833. Epub 2022 May 16 doi: 10.1161/JAHA.121.024833. PMID: 35574959Free PMC Article
Kapłon-Cieślicka A, Benson L, Chioncel O, Crespo-Leiro MG, Coats AJS, Anker SD, Filippatos G, Ruschitzka F, Hage C, Drożdż J, Seferovic P, Rosano GMC, Piepoli M, Mebazaa A, McDonagh T, Lainscak M, Savarese G, Ferrari R, Maggioni AP, Lund LH; on behalf of the Heart Failure Association (HFA) of the European Society of Cardiology (ESC) and the ESC Heart Failure Long-Term Registry Investigators.
Eur J Heart Fail 2022 Feb;24(2):335-350. Epub 2022 Jan 10 doi: 10.1002/ejhf.2408. PMID: 34962044
Minatoguchi S
J Cardiol 2022 Jun;79(6):691-697. Epub 2021 Dec 17 doi: 10.1016/j.jjcc.2021.11.016. PMID: 34924233
Narita K, Amiya E
Heart Fail Rev 2022 Jul;27(4):1001-1016. Epub 2021 May 4 doi: 10.1007/s10741-021-10116-7. PMID: 33945055

Clinical prediction guides

Butt JH, Dewan P, DeFilippis EM, Biering-Sørensen T, Docherty KF, Jhund PS, Kosiborod MN, Martinez FA, Bengtsson O, Johansen ND, Langkilde AM, Sjöstrand M, Vaduganathan M, Solomon SD, Sabatine MS, Køber L, Fiuzat M, McMurray JJV
JACC Heart Fail 2022 Aug;10(8):543-555. Epub 2022 Jun 8 doi: 10.1016/j.jchf.2022.03.009. PMID: 35902157
Kosiborod MN, Angermann CE, Collins SP, Teerlink JR, Ponikowski P, Biegus J, Comin-Colet J, Ferreira JP, Mentz RJ, Nassif ME, Psotka MA, Tromp J, Brueckmann M, Blatchford JP, Salsali A, Voors AA
Circulation 2022 Jul 26;146(4):279-288. Epub 2022 Apr 4 doi: 10.1161/CIRCULATIONAHA.122.059725. PMID: 35377706Free PMC Article
Leszek P, Waś D, Bartolik K, Witczak K, Kleinork A, Maruszewski B, Brukało K, Rolska-Wójcik P, Celińska-Spodar M, Hryniewiecki T, Załęska-Kocięcka M
ESC Heart Fail 2022 Jun;9(3):1553-1563. Epub 2022 Mar 24 doi: 10.1002/ehf2.13900. PMID: 35322601Free PMC Article
Jayagopal PB, Sastry SL, Nanjappa V, Abdullakutty J, Joseph J, Vaidyanathan PR, Kabra N, Manokar P, Ghanta SS, Sharma V, Mishra TK, Jathappa N, Singh V, Routray SN, Mandal S, Bhalla N, Dorairaj P, Mehta N, Kumbla D, Rane AR, Matia TK, Jain D, Rege G, Modi S, Chopra VK, Mohanan PP, Geevar Zachariah A, Ravindranath KS, Chakraborty R, Srinivas BC, Raghu TR, Manjunath CN
Int J Cardiol 2022 Jun 1;356:73-78. Epub 2022 Mar 13 doi: 10.1016/j.ijcard.2022.03.021. PMID: 35296433
Razuk V, Chiarito M, Cao D, Nicolas J, Pivato CA, Camaj A, Power D, Beerkens F, Jones D, Alter A, Mathew A, Spirito A, Contreras JP, Dangas GD, Mehran R
Eur Heart J Cardiovasc Pharmacother 2022 Sep 3;8(6):557-567. doi: 10.1093/ehjcvp/pvac001. PMID: 35021205

Recent systematic reviews

Younes AM, Salem M, Maraey A, Nomigolzar S, Sewell K, Khalil M, Elzanaty A, Saeyeldin A, Dar M
Int J Cardiol 2022 Nov 1;366:51-56. Epub 2022 Jun 29 doi: 10.1016/j.ijcard.2022.06.059. PMID: 35777490
Huang Z, Liu T, Chair SY
Int J Nurs Stud 2022 Aug;132:104255. Epub 2022 Apr 20 doi: 10.1016/j.ijnurstu.2022.104255. PMID: 35623153
Razaghizad A, Oulousian E, Randhawa VK, Ferreira JP, Brophy JM, Greene SJ, Guida J, Felker GM, Fudim M, Tsoukas M, Peters TM, Mavrakanas TA, Giannetti N, Ezekowitz J, Sharma A
J Am Heart Assoc 2022 May 17;11(10):e024833. Epub 2022 May 16 doi: 10.1161/JAHA.121.024833. PMID: 35574959Free PMC Article
Emmons-Bell S, Johnson C, Roth G
Heart 2022 Aug 11;108(17):1351-1360. doi: 10.1136/heartjnl-2021-320131. PMID: 35042750Free PMC Article
Razuk V, Chiarito M, Cao D, Nicolas J, Pivato CA, Camaj A, Power D, Beerkens F, Jones D, Alter A, Mathew A, Spirito A, Contreras JP, Dangas GD, Mehran R
Eur Heart J Cardiovasc Pharmacother 2022 Sep 3;8(6):557-567. doi: 10.1093/ehjcvp/pvac001. PMID: 35021205

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