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Heart block

MedGen UID:
42363
Concept ID:
C0018794
Disease or Syndrome; Finding
Synonyms: Block, Heart; Blocks, Heart; Heart Block; Heart Blocks
SNOMED CT: Heart block (233916004); HB - Heart block (233916004)
 
HPO: HP:0012722

Definition

Impaired conduction of cardiac impulse occurring anywhere along the conduction pathway. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHeart block

Conditions with this feature

Meier-Gorlin syndrome 7
MedGen UID:
934705
Concept ID:
C4310738
Disease or Syndrome
Any Meier-Gorlin syndrome in which the cause of the disease is a mutation in the CDC45 gene.

Professional guidelines

PubMed

Strasburger JF, Eckstein G, Butler M, Noffke P, Wacker-Gussmann A
J Clin Pharmacol 2022 Sep;62 Suppl 1(Suppl 1):S53-S66. doi: 10.1002/jcph.2129. PMID: 36106782Free PMC Article
Bang V, Ganatra S, Shah SP, Dani SS, Neilan TG, Thavendiranathan P, Resnic FS, Piemonte TC, Barac A, Patel R, Sharma A, Parikh R, Chaudhry GM, Vesely M, Hayek SS, Leja M, Venesy D, Patten R, Lenihan D, Nohria A, Cooper LT
J Am Coll Cardiol 2021 Mar 2;77(8):1122-1134. doi: 10.1016/j.jacc.2020.11.074. PMID: 33632487
Kusumoto FM, Schoenfeld MH, Barrett C, Edgerton JR, Ellenbogen KA, Gold MR, Goldschlager NF, Hamilton RM, Joglar JA, Kim RJ, Lee R, Marine JE, McLeod CJ, Oken KR, Patton KK, Pellegrini CN, Selzman KA, Thompson A, Varosy PD
Circulation 2019 Aug 20;140(8):e382-e482. Epub 2018 Nov 6 doi: 10.1161/CIR.0000000000000628. PMID: 30586772

Recent clinical studies

Etiology

Steinberg L
Cardiol Clin 2023 Aug;41(3):399-410. doi: 10.1016/j.ccl.2023.03.002. PMID: 37321690
Steinberg L
Card Electrophysiol Clin 2021 Dec;13(4):691-702. doi: 10.1016/j.ccep.2021.07.006. PMID: 34689896
Carvalho JS
Best Pract Res Clin Obstet Gynaecol 2019 Jul;58:28-41. Epub 2019 Jan 9 doi: 10.1016/j.bpobgyn.2019.01.002. PMID: 30738635
Miner JJ, Kim AH
Rheum Dis Clin North Am 2014 Feb;40(1):51-60. doi: 10.1016/j.rdc.2013.10.003. PMID: 24268009
Meng C, Lockshin M
Curr Opin Rheumatol 1999 Sep;11(5):348-51. doi: 10.1097/00002281-199909000-00004. PMID: 10503653

Diagnosis

Steinberg L
Cardiol Clin 2023 Aug;41(3):399-410. doi: 10.1016/j.ccl.2023.03.002. PMID: 37321690
Flowers ME, Garber K, Temples HS
J Pediatr Health Care 2023 Sep-Oct;37(5):478-483. Epub 2023 Apr 6 doi: 10.1016/j.pedhc.2023.03.001. PMID: 37031100
Steinberg L
Card Electrophysiol Clin 2021 Dec;13(4):691-702. doi: 10.1016/j.ccep.2021.07.006. PMID: 34689896
Yildirim A, Tunaoolu FS, Karaaoac AT
Indian Pediatr 2013 May 8;50(5):483-8. doi: 10.1007/s13312-013-0156-3. PMID: 23778728
Gordon PA
Lupus 2007;16(8):642-6. doi: 10.1177/0961203307079041. PMID: 17711901

Therapy

Alabed S, Sabouni A, Al Dakhoul S, Bdaiwi Y
Cochrane Database Syst Rev 2020 Jul 23;7(7):CD007037. doi: 10.1002/14651858.CD007037.pub4. PMID: 32700759Free PMC Article
Izmirly P, Kim M, Friedman DM, Costedoat-Chalumeau N, Clancy R, Copel JA, Phoon CKL, Cuneo BF, Cohen RE, Robins K, Masson M, Wainwright BJ, Zahr N, Saxena A, Buyon JP
J Am Coll Cardiol 2020 Jul 21;76(3):292-302. doi: 10.1016/j.jacc.2020.05.045. PMID: 32674792Free PMC Article
Carvalho JS
Best Pract Res Clin Obstet Gynaecol 2019 Jul;58:28-41. Epub 2019 Jan 9 doi: 10.1016/j.bpobgyn.2019.01.002. PMID: 30738635
Alabed S, Sabouni A, Al Dakhoul S, Bdaiwi Y, Frobel-Mercier AK
Cochrane Database Syst Rev 2016 Jan 28;(1):CD007037. doi: 10.1002/14651858.CD007037.pub3. PMID: 26820557
Roberts DM, Gallapatthy G, Dunuwille A, Chan BS
Br J Clin Pharmacol 2016 Mar;81(3):488-95. Epub 2015 Dec 15 doi: 10.1111/bcp.12814. PMID: 26505271Free PMC Article

Prognosis

Shreenivas S, Schloss E, Choo J, Sarembock I, Lilly S, Kereiakes D
Expert Rev Cardiovasc Ther 2019 Apr;17(4):293-304. doi: 10.1080/14779072.2019.1598264. PMID: 30912984
Wallis GA, Debich-Spicer D, Anderson RH
Orphanet J Rare Dis 2011 May 14;6:22. doi: 10.1186/1750-1172-6-22. PMID: 21569592Free PMC Article
Toogood G
Aust Fam Physician 2007 Jul;36(7):518-9, 521-4. PMID: 17619666
Lee LA
J Invest Dermatol 1993 Jan;100(1):9S-13S. doi: 10.1111/1523-1747.ep12355173. PMID: 8423406
Bexton RS, Camm AJ
Eur Heart J 1984 Mar;5 Suppl A:111-4. doi: 10.1093/eurheartj/5.suppl_a.111. PMID: 6373268

Clinical prediction guides

Teplitzky BA, McRoberts M, Ghanbari H
Heart Rhythm 2020 May;17(5 Pt B):881-888. doi: 10.1016/j.hrthm.2020.02.015. PMID: 32354454Free PMC Article
Wainwright B, Bhan R, Trad C, Cohen R, Saxena A, Buyon J, Izmirly P
Best Pract Res Clin Obstet Gynaecol 2020 Apr;64:41-51. Epub 2019 Oct 8 doi: 10.1016/j.bpobgyn.2019.09.001. PMID: 31685414
Miner JJ, Kim AH
Rheum Dis Clin North Am 2014 Feb;40(1):51-60. doi: 10.1016/j.rdc.2013.10.003. PMID: 24268009
Sheldon R
Prog Cardiovasc Dis 2013 Jan-Feb;55(4):390-5. doi: 10.1016/j.pcad.2012.10.011. PMID: 23472776
Meng C, Lockshin M
Curr Opin Rheumatol 1999 Sep;11(5):348-51. doi: 10.1097/00002281-199909000-00004. PMID: 10503653

Recent systematic reviews

Nagamine T, Randhawa S, Nishimura Y, Huang R, Leesutipornchai T, Benavente K, Yoshimura S, Zhang J, Kanitsorphan C
Pacing Clin Electrophysiol 2022 Apr;45(4):556-566. Epub 2022 Mar 3 doi: 10.1111/pace.14466. PMID: 35182433Free PMC Article
Alabed S, Sabouni A, Al Dakhoul S, Bdaiwi Y
Cochrane Database Syst Rev 2020 Jul 23;7(7):CD007037. doi: 10.1002/14651858.CD007037.pub4. PMID: 32700759Free PMC Article
Buca DIP, Khalil A, Rizzo G, Familiari A, Di Giovanni S, Liberati M, Murgano D, Ricciardulli A, Fanfani F, Scambia G, D'Antonio F
Ultrasound Obstet Gynecol 2018 Mar;51(3):323-330. doi: 10.1002/uog.17546. PMID: 28603940
Kwok CS, Rashid M, Beynon R, Barker D, Patwala A, Morley-Davies A, Satchithananda D, Nolan J, Myint PK, Buchan I, Loke YK, Mamas MA
Heart 2016 May;102(9):672-80. Epub 2016 Feb 15 doi: 10.1136/heartjnl-2015-308956. PMID: 26879241
Alabed S, Sabouni A, Al Dakhoul S, Bdaiwi Y, Frobel-Mercier AK
Cochrane Database Syst Rev 2016 Jan 28;(1):CD007037. doi: 10.1002/14651858.CD007037.pub3. PMID: 26820557

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