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Glioblastoma

MedGen UID:
42228
Concept ID:
C0017636
Neoplastic Process
Synonyms: Giant cell glioblastoma (histologic variant); Gliosarcoma (histologic variant)
SNOMED CT: Glioblastoma (63634009); Glioblastoma, no ICD-O subtype (63634009); Glioblastoma, no International Classification of Diseases for Oncology subtype (63634009)
 
Orphanet: ORPHA360

Definition

Glioblastomas are malignant astrocytic tumors (grade IV according to the WHO classification). [from ORDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  

Recent clinical studies

Etiology

Hwang K, Lee JH, Kim SH, Go KO, Ji SY, Han JH, Kim CY
In Vivo 2021 Jul-Aug;35(4):2015-2023. doi: 10.21873/invivo.12470. PMID: 34182476Free PMC Article
Hallaert G, Pinson H, Van den Broecke C, Sweldens C, Van Roost D, Kalala JP, Boterberg T
Acta Oncol 2021 May;60(5):613-619. Epub 2021 Mar 9 doi: 10.1080/0284186X.2021.1893899. PMID: 33689536
Beig Zali S, Alinezhad F, Ranjkesh M, Daghighi MH, Poureisa M
Neuroradiol J 2021 Jun;34(3):205-212. Epub 2021 Jan 8 doi: 10.1177/1971400920983678. PMID: 33417503Free PMC Article
Muglia R, Simonelli M, Pessina F, Morenghi E, Navarria P, Persico P, Lorenzi E, Dipasquale A, Grimaldi M, Scorsetti M, Santoro A, Politi LS
Eur Radiol 2021 Jun;31(6):4079-4086. Epub 2020 Nov 17 doi: 10.1007/s00330-020-07471-8. PMID: 33201284
Choi Y, Nam Y, Jang J, Shin NY, Lee YS, Ahn KJ, Kim BS, Park JS, Jeon SS, Hong YG
Eur Radiol 2021 Apr;31(4):2084-2093. Epub 2020 Oct 2 doi: 10.1007/s00330-020-07335-1. PMID: 33006658

Diagnosis

Zhao HF, Zhou XM, Wang J, Chen FF, Wu CP, Diao PY, Cai LR, Chen L, Xu YW, Liu J, Li ZY, Liu WL, Chen ZP, Huang GD, Li WP
J Transl Med 2021 Aug 30;19(1):372. doi: 10.1186/s12967-021-02979-z. PMID: 34461927Free PMC Article
Shiras A, Mondal A
Biochim Biophys Acta Rev Cancer 2021 Aug;1876(1):188551. Epub 2021 Apr 20 doi: 10.1016/j.bbcan.2021.188551. PMID: 33892052
Beig Zali S, Alinezhad F, Ranjkesh M, Daghighi MH, Poureisa M
Neuroradiol J 2021 Jun;34(3):205-212. Epub 2021 Jan 8 doi: 10.1177/1971400920983678. PMID: 33417503Free PMC Article
Picart T, Meyronet D, Pallud J, Dumot C, Metellus P, Zouaoui S, Berhouma M, Ducray F, Bauchet L, Guyotat J; French Brain Tumor DataBase.; Club de Neuro-Oncologie of the Société Française de Neurochirurgie.
J Cancer Res Clin Oncol 2021 Jun;147(6):1843-1856. Epub 2021 Jan 5 doi: 10.1007/s00432-020-03474-6. PMID: 33399987
Muglia R, Simonelli M, Pessina F, Morenghi E, Navarria P, Persico P, Lorenzi E, Dipasquale A, Grimaldi M, Scorsetti M, Santoro A, Politi LS
Eur Radiol 2021 Jun;31(6):4079-4086. Epub 2020 Nov 17 doi: 10.1007/s00330-020-07471-8. PMID: 33201284

Therapy

Hwang K, Lee JH, Kim SH, Go KO, Ji SY, Han JH, Kim CY
In Vivo 2021 Jul-Aug;35(4):2015-2023. doi: 10.21873/invivo.12470. PMID: 34182476Free PMC Article
Lah Turnšek T, Jiao X, Novak M, Jammula S, Cicero G, Ashton AW, Joyce D, Pestell RG
Int J Mol Sci 2021 Apr 24;22(9) doi: 10.3390/ijms22094464. PMID: 33923334Free PMC Article
Mattei V, Santilli F, Martellucci S, Delle Monache S, Fabrizi J, Colapietro A, Angelucci A, Festuccia C
Int J Mol Sci 2021 Apr 8;22(8) doi: 10.3390/ijms22083863. PMID: 33917954Free PMC Article
Lv F, Du Q, Li L, Xi X, Liu Q, Li W, Liu S
Eur J Pharmacol 2021 Jun 5;900:174069. Epub 2021 Mar 31 doi: 10.1016/j.ejphar.2021.174069. PMID: 33811837
Lasri A, Sturrock M
J Theor Biol 2021 Jul 21;521:110662. Epub 2021 Mar 6 doi: 10.1016/j.jtbi.2021.110662. PMID: 33684406

Prognosis

Zhao HF, Zhou XM, Wang J, Chen FF, Wu CP, Diao PY, Cai LR, Chen L, Xu YW, Liu J, Li ZY, Liu WL, Chen ZP, Huang GD, Li WP
J Transl Med 2021 Aug 30;19(1):372. doi: 10.1186/s12967-021-02979-z. PMID: 34461927Free PMC Article
Shiras A, Mondal A
Biochim Biophys Acta Rev Cancer 2021 Aug;1876(1):188551. Epub 2021 Apr 20 doi: 10.1016/j.bbcan.2021.188551. PMID: 33892052
Burghardt I, Schroeder JJ, Weiss T, Gramatzki D, Weller M
Mol Cell Biochem 2021 Aug;476(8):2963-2973. Epub 2021 Mar 26 doi: 10.1007/s11010-021-04128-y. PMID: 33772427Free PMC Article
Lasri A, Sturrock M
J Theor Biol 2021 Jul 21;521:110662. Epub 2021 Mar 6 doi: 10.1016/j.jtbi.2021.110662. PMID: 33684406
Beig Zali S, Alinezhad F, Ranjkesh M, Daghighi MH, Poureisa M
Neuroradiol J 2021 Jun;34(3):205-212. Epub 2021 Jan 8 doi: 10.1177/1971400920983678. PMID: 33417503Free PMC Article

Clinical prediction guides

Shiras A, Mondal A
Biochim Biophys Acta Rev Cancer 2021 Aug;1876(1):188551. Epub 2021 Apr 20 doi: 10.1016/j.bbcan.2021.188551. PMID: 33892052
Hallaert G, Pinson H, Van den Broecke C, Sweldens C, Van Roost D, Kalala JP, Boterberg T
Acta Oncol 2021 May;60(5):613-619. Epub 2021 Mar 9 doi: 10.1080/0284186X.2021.1893899. PMID: 33689536
Beig Zali S, Alinezhad F, Ranjkesh M, Daghighi MH, Poureisa M
Neuroradiol J 2021 Jun;34(3):205-212. Epub 2021 Jan 8 doi: 10.1177/1971400920983678. PMID: 33417503Free PMC Article
Picart T, Meyronet D, Pallud J, Dumot C, Metellus P, Zouaoui S, Berhouma M, Ducray F, Bauchet L, Guyotat J; French Brain Tumor DataBase.; Club de Neuro-Oncologie of the Société Française de Neurochirurgie.
J Cancer Res Clin Oncol 2021 Jun;147(6):1843-1856. Epub 2021 Jan 5 doi: 10.1007/s00432-020-03474-6. PMID: 33399987
Choi Y, Nam Y, Jang J, Shin NY, Lee YS, Ahn KJ, Kim BS, Park JS, Jeon SS, Hong YG
Eur Radiol 2021 Apr;31(4):2084-2093. Epub 2020 Oct 2 doi: 10.1007/s00330-020-07335-1. PMID: 33006658

Recent systematic reviews

Farrell C, Shi W, Bodman A, Olson JJ
J Neurooncol 2020 Nov;150(2):269-359. Epub 2020 Nov 19 doi: 10.1007/s11060-020-03607-4. PMID: 33215345
Ziu M, Kim BYS, Jiang W, Ryken T, Olson JJ
J Neurooncol 2020 Nov;150(2):215-267. Epub 2020 Nov 19 doi: 10.1007/s11060-020-03612-7. PMID: 33215344
Velázquez Vega JE, Brat DJ, Ryken TC, Olson JJ
J Neurooncol 2020 Nov;150(2):143-164. Epub 2020 Nov 19 doi: 10.1007/s11060-020-03616-3. PMID: 33215342
Domino JS, Ormond DR, Germano IM, Sami M, Ryken TC, Olson JJ
J Neurooncol 2020 Nov;150(2):121-142. Epub 2020 Nov 19 doi: 10.1007/s11060-020-03606-5. PMID: 33215341
Montemurro N, Anania Y, Cagnazzo F, Perrini P
Clin Neurol Neurosurg 2020 Aug;195:105942. Epub 2020 May 21 doi: 10.1016/j.clineuro.2020.105942. PMID: 32470780

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