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Disorder of orbital region

MedGen UID:
5092
Concept ID:
C0015397
Disease or Syndrome
Synonym: Disease of orbital region
SNOMED CT: Disorder of eye (371405004); Disorder of eye region (371409005); Disease of eyeball (371405004); Disorder of globe (371405004); Disorder of eyeball (371405004); Ophthalmological disorder (371409005); Disorder of orbital region (371409005); Eye disorder (371405004); Disorder of eye proper (371405004)
 
Monarch Initiative: MONDO:0002022

Definition

A non-neoplastic or neoplastic disorder that affects the eye. Representative examples include conjunctivitis, glaucoma, cataract, conjunctival squamous cell carcinoma, uveal melanoma, and retinoblastoma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • Disorder of orbital region

Professional guidelines

PubMed

Stein JD, Khawaja AP, Weizer JS
JAMA 2021 Jan 12;325(2):164-174. doi: 10.1001/jama.2020.21899. PMID: 33433580
Höglinger GU, Respondek G, Stamelou M, Kurz C, Josephs KA, Lang AE, Mollenhauer B, Müller U, Nilsson C, Whitwell JL, Arzberger T, Englund E, Gelpi E, Giese A, Irwin DJ, Meissner WG, Pantelyat A, Rajput A, van Swieten JC, Troakes C, Antonini A, Bhatia KP, Bordelon Y, Compta Y, Corvol JC, Colosimo C, Dickson DW, Dodel R, Ferguson L, Grossman M, Kassubek J, Krismer F, Levin J, Lorenzl S, Morris HR, Nestor P, Oertel WH, Poewe W, Rabinovici G, Rowe JB, Schellenberg GD, Seppi K, van Eimeren T, Wenning GK, Boxer AL, Golbe LI, Litvan I; Movement Disorder Society-endorsed PSP Study Group
Mov Disord 2017 Jun;32(6):853-864. Epub 2017 May 3 doi: 10.1002/mds.26987. PMID: 28467028Free PMC Article
Wingerchuk DM, Banwell B, Bennett JL, Cabre P, Carroll W, Chitnis T, de Seze J, Fujihara K, Greenberg B, Jacob A, Jarius S, Lana-Peixoto M, Levy M, Simon JH, Tenembaum S, Traboulsee AL, Waters P, Wellik KE, Weinshenker BG; International Panel for NMO Diagnosis
Neurology 2015 Jul 14;85(2):177-89. Epub 2015 Jun 19 doi: 10.1212/WNL.0000000000001729. PMID: 26092914Free PMC Article

Recent clinical studies

Etiology

Dammacco R
Clin Exp Med 2018 May;18(2):135-149. Epub 2017 Dec 14 doi: 10.1007/s10238-017-0479-9. PMID: 29243035
Seifi M, Walter MA
Clin Genet 2018 Jun;93(6):1123-1130. Epub 2018 Jan 25 doi: 10.1111/cge.13148. PMID: 28972279
Solebo AL, Teoh L, Rahi J
Arch Dis Child 2017 Sep;102(9):853-857. Epub 2017 May 2 doi: 10.1136/archdischild-2016-310532. PMID: 28465303
Milston R, Madigan MC, Sebag J
Surv Ophthalmol 2016 Mar-Apr;61(2):211-27. Epub 2015 Dec 8 doi: 10.1016/j.survophthal.2015.11.008. PMID: 26679984
Duker JS, Kaiser PK, Binder S, de Smet MD, Gaudric A, Reichel E, Sadda SR, Sebag J, Spaide RF, Stalmans P
Ophthalmology 2013 Dec;120(12):2611-2619. Epub 2013 Sep 17 doi: 10.1016/j.ophtha.2013.07.042. PMID: 24053995

Diagnosis

Couser NL, Brooks BP, Drack AV, Shankar SP
Ophthalmic Genet 2021 Apr;42(2):110-113. Epub 2021 Jan 12 doi: 10.1080/13816810.2020.1868011. PMID: 33432855
Shah SM, Khanna CL
Mayo Clin Proc 2020 May;95(5):1050-1058. doi: 10.1016/j.mayocp.2020.03.018. PMID: 32370836
Hsu JI, Pflugfelder SC, Kim SJ
Cutis 2019 Sep;104(3):189-193. PMID: 31675394
Muthiah S, Radhakrishnan N
Indian J Pediatr 2017 Dec;84(12):945-952. Epub 2017 Jul 14 doi: 10.1007/s12098-017-2409-y. PMID: 28707045
Shao L, Wei W
Chin Med J (Engl) 2014;127(8):1566-71. PMID: 24762607

Therapy

Laihia J, Kaarniranta K
Biomolecules 2020 May 25;10(5) doi: 10.3390/biom10050809. PMID: 32466265Free PMC Article
Clark SJ, Bishop PN
Semin Immunopathol 2018 Jan;40(1):65-74. Epub 2017 Sep 25 doi: 10.1007/s00281-017-0649-6. PMID: 28948331Free PMC Article
Tam C, Wong JH, Cheung RCF, Zuo T, Ng TB
Appl Microbiol Biotechnol 2017 Oct;101(19):7091-7111. Epub 2017 Aug 8 doi: 10.1007/s00253-017-8433-z. PMID: 28791440
Agarwal A, Rajagopalan N, Hassan M, Sadiq MA, Soliman MK, Afridi R, Sepah YJ, Nguyen QD
Dev Ophthalmol 2016;55:276-81. Epub 2015 Oct 26 doi: 10.1159/000438951. PMID: 26501229
Barry RJ, Denniston AK
Curr Pharm Des 2015;21(32):4682-7. doi: 10.2174/1381612821666150909094907. PMID: 26350535

Prognosis

Muthiah S, Radhakrishnan N
Indian J Pediatr 2017 Dec;84(12):945-952. Epub 2017 Jul 14 doi: 10.1007/s12098-017-2409-y. PMID: 28707045
González-Martín-Moro J, Zarallo-Gallardo J
Arch Soc Esp Oftalmol 2016 Nov;91(11):526-534. Epub 2016 Apr 25 doi: 10.1016/j.oftal.2016.03.014. PMID: 27125187
Grzybowski A, Nita M, Virmond M
Clin Dermatol 2015 Jan-Feb;33(1):79-89. doi: 10.1016/j.clindermatol.2014.07.003. PMID: 25432813
Hodge C, Lawless M
Aust Fam Physician 2008 Jul;37(7):506-9. PMID: 18592066
van Den Heuvel JP, Baarsma GS, Zahn KJ
Doc Ophthalmol 1977 Sep 30;44(1):105-11. doi: 10.1007/BF00171461. PMID: 923400

Clinical prediction guides

Guggenheim JA, Ghorbani Mojarrad N, Williams C, Flitcroft DI
Ophthalmic Physiol Opt 2017 Sep;37(5):549-556. doi: 10.1111/opo.12403. PMID: 28836387
Ohno-Matsui K, Kawasaki R, Jonas JB, Cheung CM, Saw SM, Verhoeven VJ, Klaver CC, Moriyama M, Shinohara K, Kawasaki Y, Yamazaki M, Meuer S, Ishibashi T, Yasuda M, Yamashita H, Sugano A, Wang JJ, Mitchell P, Wong TY; META-analysis for Pathologic Myopia (META-PM) Study Group
Am J Ophthalmol 2015 May;159(5):877-83.e7. Epub 2015 Jan 26 doi: 10.1016/j.ajo.2015.01.022. PMID: 25634530
Shao L, Wei W
Chin Med J (Engl) 2014;127(8):1566-71. PMID: 24762607
Parikh R, Mathai A, Parikh S, Chandra Sekhar G, Thomas R
Indian J Ophthalmol 2008 Jan-Feb;56(1):45-50. doi: 10.4103/0301-4738.37595. PMID: 18158403Free PMC Article
Lancet 1990 May 5;335(8697):1078-80. PMID: 1970380

Recent systematic reviews

Zhu Z, Chen Y, Tan Z, Xiong R, McGuinness MB, Müller A
Br J Ophthalmol 2023 Feb;107(2):160-166. Epub 2021 Nov 29 doi: 10.1136/bjophthalmol-2021-319306. PMID: 34844916
Chan HN, Zhang XJ, Ling XT, Bui CH, Wang YM, Ip P, Chu WK, Chen LJ, Tham CC, Yam JC, Pang CP
Int J Mol Sci 2022 Apr 11;23(8) doi: 10.3390/ijms23084226. PMID: 35457041Free PMC Article
GBD 2019 Blindness and Vision Impairment Collaborators; Vision Loss Expert Group of the Global Burden of Disease Study
Lancet Glob Health 2021 Feb;9(2):e144-e160. Epub 2020 Dec 1 doi: 10.1016/S2214-109X(20)30489-7. PMID: 33275949Free PMC Article
Steel D
BMJ Clin Evid 2014 Mar 3;2014 PMID: 24807890Free PMC Article
Azari AA, Barney NP
JAMA 2013 Oct 23;310(16):1721-9. doi: 10.1001/jama.2013.280318. PMID: 24150468Free PMC Article

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