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Disorder of kidney due to diabetes mellitus

MedGen UID:
8352
Concept ID:
C0011881
Disease or Syndrome
Synonyms: Diabetic Kidney Disease; Diabetic Kidney Diseases; Diabetic Nephropathies; Diabetic Nephropathy; Kidney Disease, Diabetic; Kidney Diseases, Diabetic; Nephropathies, Diabetic; Nephropathy, Diabetic
SNOMED CT: Diabetic nephropathy (127013003); Renal disorder associated with diabetes mellitus (127013003); Diabetic renal disease (127013003); Kidney disorder due to diabetes mellitus (127013003); Disorder of kidney due to diabetes mellitus (127013003)

Definition

Progressive kidney disorder caused by vascular damage to the glomerular capillaries, in patients with diabetes mellitus. It is usually manifested with nephritic syndrome and glomerulosclerosis. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDisorder of kidney due to diabetes mellitus

Recent clinical studies

Etiology

Zhu H, Liu X, Zhang C, Li Q, An X, Liu S, Wu L, Zhang B, Yuan Y, Xing C
J Diabetes Complications 2019 Nov;33(11):107419. Epub 2019 Aug 19 doi: 10.1016/j.jdiacomp.2019.107419. PMID: 31473080
Subramanian S, Hirsch IB
Curr Diab Rep 2018 Feb 15;18(3):13. doi: 10.1007/s11892-018-0979-3. PMID: 29450720
Smith MJ, Simmons KM, Cambier JC
Nat Rev Nephrol 2017 Oct 17;13(11):712-720. doi: 10.1038/nrneph.2017.138. PMID: 29038537Free PMC Article
Bherwani S, Ahirwar AK, Saumya AS, Sandhya AS, Prajapat B, Patel S, Jibhkate SB, Singh R, Ghotekar LH
Diabetes Metab Syndr 2017 Nov;11 Suppl 1:S365-S368. Epub 2017 Mar 6 doi: 10.1016/j.dsx.2017.03.017. PMID: 28283394
Gandhi J, Dagur G, Warren K, Smith NL, Khan SA
Curr Diabetes Rev 2017;13(5):498-518. doi: 10.2174/1573399812666161019162747. PMID: 27774877

Diagnosis

Chen Y, Zhang W, Wang N, Wang Y, Wang C, Wan H, Lu Y
J Diabetes Res 2020;2020:4798947. Epub 2020 Mar 28 doi: 10.1155/2020/4798947. PMID: 32337292Free PMC Article
Zhu H, Liu X, Zhang C, Li Q, An X, Liu S, Wu L, Zhang B, Yuan Y, Xing C
J Diabetes Complications 2019 Nov;33(11):107419. Epub 2019 Aug 19 doi: 10.1016/j.jdiacomp.2019.107419. PMID: 31473080
Subramanian S, Hirsch IB
Curr Diab Rep 2018 Feb 15;18(3):13. doi: 10.1007/s11892-018-0979-3. PMID: 29450720
Smith MJ, Simmons KM, Cambier JC
Nat Rev Nephrol 2017 Oct 17;13(11):712-720. doi: 10.1038/nrneph.2017.138. PMID: 29038537Free PMC Article
Gandhi J, Dagur G, Warren K, Smith NL, Khan SA
Curr Diabetes Rev 2017;13(5):498-518. doi: 10.2174/1573399812666161019162747. PMID: 27774877

Therapy

Nicotera R, Casarella A, Longhitano E, Bolignano D, Andreucci M, De Sarro G, Cernaro V, Russo E, Coppolino G
Pharmacol Res 2020 Sep;159:105019. Epub 2020 Jun 15 doi: 10.1016/j.phrs.2020.105019. PMID: 32553713
Yang S, Ma C, Wu H, Zhang H, Yuan F, Yang G, Yang Q, Jia L, Liang Z, Kang L
Pharmacol Res 2020 Mar;153:104678. Epub 2020 Jan 31 doi: 10.1016/j.phrs.2020.104678. PMID: 32014572
Di Vincenzo A, Tana C, El Hadi H, Pagano C, Vettor R, Rossato M
Int J Mol Sci 2019 Oct 15;20(20) doi: 10.3390/ijms20205101. PMID: 31618817Free PMC Article
Yang YY, Shi LX, Li JH, Yao LY, Xiang DX
Mol Med Rep 2019 Mar;19(3):2245-2253. Epub 2019 Jan 17 doi: 10.3892/mmr.2019.9875. PMID: 30664213Free PMC Article
Zilişteanu DS, Atasie T, Voiculescu M
Rom J Intern Med 2015 Apr-Jun;53(2):161-9. doi: 10.1515/rjim-2015-0022. PMID: 26402986

Prognosis

Zhu H, Liu X, Zhang C, Li Q, An X, Liu S, Wu L, Zhang B, Yuan Y, Xing C
J Diabetes Complications 2019 Nov;33(11):107419. Epub 2019 Aug 19 doi: 10.1016/j.jdiacomp.2019.107419. PMID: 31473080
Ray S, Beatrice AM, Ghosh A, Pramanik S, Bhattacharjee R, Ghosh S, Raychaudhury A, Mukhopadhyay S, Chowdhury S
Diabetes Metab Syndr 2017 Dec;11 Suppl 2:S931-S937. Epub 2017 Jul 8 doi: 10.1016/j.dsx.2017.07.019. PMID: 28728874
Gandhi J, Dagur G, Warren K, Smith NL, Khan SA
Curr Diabetes Rev 2017;13(5):498-518. doi: 10.2174/1573399812666161019162747. PMID: 27774877
Wieczorek A, Matusiak L, Szepietowski JC
Iran J Kidney Dis 2016 May;10(3):164-7. PMID: 27225725
Dong Y, Wang WP, Lin P, Fan P, Mao F
Clin Hemorheol Microcirc 2016;62(3):229-38. doi: 10.3233/CH-151967. PMID: 26444598

Clinical prediction guides

Zhang Q, He L, Dong Y, Fei Y, Wen J, Li X, Guan J, Liu F, Zhou T, Li Z, Fan Y, Wang N
FASEB J 2020 Jun;34(6):7500-7519. Epub 2020 Apr 12 doi: 10.1096/fj.201903038R. PMID: 32281218
Chao CT, Wang J, Huang JW, Chan DC, Hung KY, Chien KL; COhort of GEriatric Nephrology in NTUH (COGENT) study group.
Osteoporos Int 2020 Apr;31(4):699-708. Epub 2020 Feb 27 doi: 10.1007/s00198-020-05353-9. PMID: 32103279
Takamatsu K
Clin Exp Nephrol 2020 Jan;24(1):53-62. Epub 2019 Sep 23 doi: 10.1007/s10157-019-01792-9. PMID: 31544221Free PMC Article
Zhu H, Liu X, Zhang C, Li Q, An X, Liu S, Wu L, Zhang B, Yuan Y, Xing C
J Diabetes Complications 2019 Nov;33(11):107419. Epub 2019 Aug 19 doi: 10.1016/j.jdiacomp.2019.107419. PMID: 31473080
Dong Y, Wang WP, Lin P, Fan P, Mao F
Clin Hemorheol Microcirc 2016;62(3):229-38. doi: 10.3233/CH-151967. PMID: 26444598

Recent systematic reviews

He D, Zhang Y, Zhang W, Xing Y, Guo Y, Wang F, Jia J, Yan T, Liu Y, Lin S
Horm Metab Res 2020 May;52(5):289-297. Epub 2020 Mar 27 doi: 10.1055/a-1138-0959. PMID: 32219798
Jiang W, Wang J, Shen X, Lu W, Wang Y, Li W, Gao Z, Xu J, Li X, Liu R, Zheng M, Chang B, Li J, Yang J, Chang B
Diabetes Care 2020 Apr;43(4):925-933. doi: 10.2337/dc19-1897. PMID: 32198286
Vlachou E, Ntikoudi A, Govina O, Lavdaniti M, Kotsalas N, Tsartsalis A, Dimitriadis G
Curr Clin Pharmacol 2020;15(3):234-242. doi: 10.2174/1574884715666200303112753. PMID: 32124701
Liu X, Ma L, Li Z
J Endocrinol Invest 2020 Jul;43(7):959-972. Epub 2020 Jan 14 doi: 10.1007/s40618-020-01179-8. PMID: 31939197
Singh S, Sonkar SK, Sonkar GK, Mahdi AA
Diabetes Metab Res Rev 2019 Jul;35(5):e3155. Epub 2019 Apr 3 doi: 10.1002/dmrr.3155. PMID: 30892801

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