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Hypergammaglobulinemia

MedGen UID:
9362
Concept ID:
C0020455
Disease or Syndrome
Synonyms: Hypergammaglobulinemias; Hyperimmunoglobulinemia; Hyperimmunoglobulinemias
SNOMED CT: Hypergammaglobulinemia (127388009)
 
HPO: HP:0010702

Definition

A laboratory test result indicating abnormally high concentrations of gamma globulins in the blood. [from NCI]

Recent clinical studies

Etiology

Cacciola I, Filomia R, Alibrandi A, Franzè MS, Caccamo G, Maimone S, Saitta C, Saffioti F, Squadrito G, Raimondo G
Liver Int 2018 Jul;38(7):1220-1229. Epub 2018 Jan 8 doi: 10.1111/liv.13649. PMID: 29194934
Ter Borg EJ, Kelder JC
Int J Rheum Dis 2017 Jul;20(7):875-881. Epub 2017 Apr 26 doi: 10.1111/1756-185X.13070. PMID: 28447402
Matar M, Rinawi F, Shamir R, Assa A
Turk J Gastroenterol 2017 Mar;28(2):131-134. Epub 2017 Jan 26 doi: 10.5152/tjg.2017.16562. PMID: 28124661
Atwell JE, Thumar B, Robinson LJ, Tobby R, Yambo P, Ome-Kaius M, Siba PM, Unger HW, Rogerson SJ, King CL, Karron RA
J Infect Dis 2016 Feb 1;213(3):423-31. Epub 2015 Aug 3 doi: 10.1093/infdis/jiv401. PMID: 26238686Free PMC Article
Lebherz-Eichinger D, Schwarzer R, Motal MC, Klaus DA, Mangold A, Ankersmit HJ, Berlakovich GA, Krenn CG, Roth GA
Biochem Med (Zagreb) 2015;25(2):252-61. Epub 2015 Jun 5 doi: 10.11613/BM.2015.026. PMID: 26110038Free PMC Article

Diagnosis

Cacciola I, Filomia R, Alibrandi A, Franzè MS, Caccamo G, Maimone S, Saitta C, Saffioti F, Squadrito G, Raimondo G
Liver Int 2018 Jul;38(7):1220-1229. Epub 2018 Jan 8 doi: 10.1111/liv.13649. PMID: 29194934
Taubert R, Hardtke-Wolenski M, Noyan F, Lalanne C, Jonigk D, Schlue J, Krech T, Lichtinghagen R, Falk CS, Schlaphoff V, Bantel H, Muratori L, Manns MP, Jaeckel E
PLoS One 2017;12(6):e0179074. Epub 2017 Jun 8 doi: 10.1371/journal.pone.0179074. PMID: 28594937Free PMC Article
Ter Borg EJ, Kelder JC
Int J Rheum Dis 2017 Jul;20(7):875-881. Epub 2017 Apr 26 doi: 10.1111/1756-185X.13070. PMID: 28447402
Matar M, Rinawi F, Shamir R, Assa A
Turk J Gastroenterol 2017 Mar;28(2):131-134. Epub 2017 Jan 26 doi: 10.5152/tjg.2017.16562. PMID: 28124661
Jonjić N, Seili Bekafigo I, Fučkar Čupić D, Lučin K, Duletić Načinović A, Valković T
Appl Immunohistochem Mol Morphol 2016 Nov/Dec;24(10):e89-e93. doi: 10.1097/PAI.0000000000000361. PMID: 27824644

Therapy

Taubert R, Hardtke-Wolenski M, Noyan F, Lalanne C, Jonigk D, Schlue J, Krech T, Lichtinghagen R, Falk CS, Schlaphoff V, Bantel H, Muratori L, Manns MP, Jaeckel E
PLoS One 2017;12(6):e0179074. Epub 2017 Jun 8 doi: 10.1371/journal.pone.0179074. PMID: 28594937Free PMC Article
Lebherz-Eichinger D, Schwarzer R, Motal MC, Klaus DA, Mangold A, Ankersmit HJ, Berlakovich GA, Krenn CG, Roth GA
Biochem Med (Zagreb) 2015;25(2):252-61. Epub 2015 Jun 5 doi: 10.11613/BM.2015.026. PMID: 26110038Free PMC Article
Polprasert C, Wongchitrat C, Assanasen T, Prayongratana K
J Med Assoc Thai 2009 Jun;92 Suppl 3:S65-8. PMID: 19702069
Kurosawa S, Akiyama N, Ohwada A, Warabi M, Suenaga M, Kojima M, Tomiyama J
Jpn J Clin Oncol 2009 Oct;39(10):682-5. Epub 2009 Jul 8 doi: 10.1093/jjco/hyp073. PMID: 19586961
Kubota T, Moritani S, Yoshino T, Nagai H, Terasaki H
Am J Ophthalmol 2008 Jun;145(6):1002-1006. Epub 2008 Mar 12 doi: 10.1016/j.ajo.2008.01.006. PMID: 18336788

Prognosis

Cacciola I, Filomia R, Alibrandi A, Franzè MS, Caccamo G, Maimone S, Saitta C, Saffioti F, Squadrito G, Raimondo G
Liver Int 2018 Jul;38(7):1220-1229. Epub 2018 Jan 8 doi: 10.1111/liv.13649. PMID: 29194934
Taubert R, Hardtke-Wolenski M, Noyan F, Lalanne C, Jonigk D, Schlue J, Krech T, Lichtinghagen R, Falk CS, Schlaphoff V, Bantel H, Muratori L, Manns MP, Jaeckel E
PLoS One 2017;12(6):e0179074. Epub 2017 Jun 8 doi: 10.1371/journal.pone.0179074. PMID: 28594937Free PMC Article
Jonjić N, Seili Bekafigo I, Fučkar Čupić D, Lučin K, Duletić Načinović A, Valković T
Appl Immunohistochem Mol Morphol 2016 Nov/Dec;24(10):e89-e93. doi: 10.1097/PAI.0000000000000361. PMID: 27824644
Lebherz-Eichinger D, Schwarzer R, Motal MC, Klaus DA, Mangold A, Ankersmit HJ, Berlakovich GA, Krenn CG, Roth GA
Biochem Med (Zagreb) 2015;25(2):252-61. Epub 2015 Jun 5 doi: 10.11613/BM.2015.026. PMID: 26110038Free PMC Article
Ohno H, Tanaka H, Sakai H, Katsurada T, Yoshida Y
Int J Hematol 2005 Jan;81(1):62-5. PMID: 15717691

Clinical prediction guides

Cacciola I, Filomia R, Alibrandi A, Franzè MS, Caccamo G, Maimone S, Saitta C, Saffioti F, Squadrito G, Raimondo G
Liver Int 2018 Jul;38(7):1220-1229. Epub 2018 Jan 8 doi: 10.1111/liv.13649. PMID: 29194934
Taubert R, Hardtke-Wolenski M, Noyan F, Lalanne C, Jonigk D, Schlue J, Krech T, Lichtinghagen R, Falk CS, Schlaphoff V, Bantel H, Muratori L, Manns MP, Jaeckel E
PLoS One 2017;12(6):e0179074. Epub 2017 Jun 8 doi: 10.1371/journal.pone.0179074. PMID: 28594937Free PMC Article
Ter Borg EJ, Kelder JC
Int J Rheum Dis 2017 Jul;20(7):875-881. Epub 2017 Apr 26 doi: 10.1111/1756-185X.13070. PMID: 28447402
Tanji H, Okada H, Igari R, Yamaguchi Y, Sato H, Takahashi Y, Koyama S, Arawaka S, Wada M, Kawanami T, Wakabayashi K, Kato T
Intern Med 2016;55(14):1911-6. Epub 2016 Jul 15 doi: 10.2169/internalmedicine.55.5854. PMID: 27432102
Atwell JE, Thumar B, Robinson LJ, Tobby R, Yambo P, Ome-Kaius M, Siba PM, Unger HW, Rogerson SJ, King CL, Karron RA
J Infect Dis 2016 Feb 1;213(3):423-31. Epub 2015 Aug 3 doi: 10.1093/infdis/jiv401. PMID: 26238686Free PMC Article

Recent systematic reviews

Nishishinya MB, Pereda CA, Muñoz-Fernández S, Pego-Reigosa JM, Rúa-Figueroa I, Andreu JL, Fernández-Castro M, Rosas J, Loza Santamaría E
Rheumatol Int 2015 Jan;35(1):17-26. Epub 2014 Jun 5 doi: 10.1007/s00296-014-3051-x. PMID: 24899571
Mylona EE, Baraboutis IG, Lekakis LJ, Georgiou O, Papastamopoulos V, Skoutelis A
AIDS Rev 2008 Jan-Mar;10(1):25-35. PMID: 18385778

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