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Cognitive impairment

MedGen UID:
90932
Concept ID:
C0338656
Mental or Behavioral Dysfunction
Synonyms: Cognitive Dysfunction; Cognitive Dysfunctions; Cognitive Impairment; Cognitive Impairments; Dysfunction, Cognitive; Dysfunctions, Cognitive; Impairment, Cognitive; Impairments, Cognitive
SNOMED CT: Impaired cognition (386806002); Cognitive impairment (386806002); Cognitive disturbance (386806002); Cognitive dysfunction (386806002); Cognitive decline (386806002); Cognitive deficit (386806002)
 
HPO: HP:0100543

Definition

a condition where a person has problems with the ability to think and learn [from CHV]

Recent clinical studies

Etiology

Dichgans M, Leys D
Circ Res 2017 Feb 3;120(3):573-591. doi: 10.1161/CIRCRESAHA.116.308426. PMID: 28154105
Okura M, Ogita M, Yamamoto M, Nakai T, Numata T, Arai H
Arch Gerontol Geriatr 2017 May - Jun;70:54-61. Epub 2016 Dec 29 doi: 10.1016/j.archger.2016.12.010. PMID: 28068553
Nijsse B, Visser-Meily JM, van Mierlo ML, Post MW, de Kort PL, van Heugten CM
Stroke 2017 Jan;48(1):98-104. Epub 2016 Nov 29 doi: 10.1161/STROKEAHA.116.014168. PMID: 27899753
Trowbridge ER, Kim D, Barletta K, Fitz V, Larkin S, Hullfish KL
Am J Obstet Gynecol 2016 Nov;215(5):663.e1-663.e6. Epub 2016 Jun 16 doi: 10.1016/j.ajog.2016.06.012. PMID: 27319369
Trevisan C, Veronese N, Bolzetta F, De Rui M, Maggi S, Zambon S, Musacchio E, Sartori L, Perissinotto E, Crepaldi G, Manzato E, Sergi G
Rejuvenation Res 2016 Dec;19(6):447-455. Epub 2016 Mar 14 doi: 10.1089/rej.2015.1768. PMID: 26778182

Diagnosis

Dichgans M, Leys D
Circ Res 2017 Feb 3;120(3):573-591. doi: 10.1161/CIRCRESAHA.116.308426. PMID: 28154105
Nijsse B, Visser-Meily JM, van Mierlo ML, Post MW, de Kort PL, van Heugten CM
Stroke 2017 Jan;48(1):98-104. Epub 2016 Nov 29 doi: 10.1161/STROKEAHA.116.014168. PMID: 27899753
Chiu HY, Lai FC, Chen PY, Tsai PS
J Am Geriatr Soc 2016 Oct;64(10):2051-2058. Epub 2016 Sep 14 doi: 10.1111/jgs.14316. PMID: 27627762
Trowbridge ER, Kim D, Barletta K, Fitz V, Larkin S, Hullfish KL
Am J Obstet Gynecol 2016 Nov;215(5):663.e1-663.e6. Epub 2016 Jun 16 doi: 10.1016/j.ajog.2016.06.012. PMID: 27319369
Trevisan C, Veronese N, Bolzetta F, De Rui M, Maggi S, Zambon S, Musacchio E, Sartori L, Perissinotto E, Crepaldi G, Manzato E, Sergi G
Rejuvenation Res 2016 Dec;19(6):447-455. Epub 2016 Mar 14 doi: 10.1089/rej.2015.1768. PMID: 26778182

Therapy

Bassiony MM, Youssef UM, Hassan MS, Salah El-Deen GM, El-Gohari H, Abdelghani M, Abdalla A, Ibrahim DH
J Clin Psychopharmacol 2017 Feb;37(1):61-66. doi: 10.1097/JCP.0000000000000617. PMID: 27918316
Chae JW, Ng T, Yeo HL, Shwe M, Gan YX, Ho HK, Chan A
PLoS One 2016;11(10):e0164204. Epub 2016 Oct 4 doi: 10.1371/journal.pone.0164204. PMID: 27701469Free PMC Article
Zhuang S, Wang HF, Wang X, Li J, Xing CM
J Clin Neurosci 2016 Nov;33:32-38. Epub 2016 Jul 27 doi: 10.1016/j.jocn.2016.02.036. PMID: 27475317
Dong J, Pi HC, Xiong ZY, Liao JL, Hao L, Liu GL, Ren YP, Wang Q, Duan LP, Zheng ZX
Am J Kidney Dis 2016 Jan;67(1):111-8. Epub 2015 Aug 6 doi: 10.1053/j.ajkd.2015.06.025. PMID: 26255306
Jia J, Wei C, Liang J, Zhou A, Zuo X, Song H, Wu L, Chen X, Chen S, Zhang J, Wu J, Wang K, Chu L, Peng D, Lv P, Guo H, Niu X, Chen Y, Dong W, Han X, Fang B, Peng M, Li D, Jia Q, Huang L
Alzheimers Dement 2016 Feb;12(2):89-99. Epub 2015 Jun 15 doi: 10.1016/j.jalz.2015.04.010. PMID: 26086183

Prognosis

Okura M, Ogita M, Yamamoto M, Nakai T, Numata T, Arai H
Arch Gerontol Geriatr 2017 May - Jun;70:54-61. Epub 2016 Dec 29 doi: 10.1016/j.archger.2016.12.010. PMID: 28068553
Nijsse B, Visser-Meily JM, van Mierlo ML, Post MW, de Kort PL, van Heugten CM
Stroke 2017 Jan;48(1):98-104. Epub 2016 Nov 29 doi: 10.1161/STROKEAHA.116.014168. PMID: 27899753
Infurna FJ, Okun MA, Grimm KJ
J Am Geriatr Soc 2016 Nov;64(11):2263-2269. Epub 2016 Oct 3 doi: 10.1111/jgs.14398. PMID: 27696342
Nakamura K, Kitamura K, Watanabe Y, Shinoda H, Sato H, Someya T
Environ Health Prev Med 2016 Nov;21(6):422-429. Epub 2016 Jun 4 doi: 10.1007/s12199-016-0542-2. PMID: 27262968Free PMC Article
Trevisan C, Veronese N, Bolzetta F, De Rui M, Maggi S, Zambon S, Musacchio E, Sartori L, Perissinotto E, Crepaldi G, Manzato E, Sergi G
Rejuvenation Res 2016 Dec;19(6):447-455. Epub 2016 Mar 14 doi: 10.1089/rej.2015.1768. PMID: 26778182

Clinical prediction guides

Okura M, Ogita M, Yamamoto M, Nakai T, Numata T, Arai H
Arch Gerontol Geriatr 2017 May - Jun;70:54-61. Epub 2016 Dec 29 doi: 10.1016/j.archger.2016.12.010. PMID: 28068553
Nijsse B, Visser-Meily JM, van Mierlo ML, Post MW, de Kort PL, van Heugten CM
Stroke 2017 Jan;48(1):98-104. Epub 2016 Nov 29 doi: 10.1161/STROKEAHA.116.014168. PMID: 27899753
Zhuang S, Wang HF, Wang X, Li J, Xing CM
J Clin Neurosci 2016 Nov;33:32-38. Epub 2016 Jul 27 doi: 10.1016/j.jocn.2016.02.036. PMID: 27475317
Trowbridge ER, Kim D, Barletta K, Fitz V, Larkin S, Hullfish KL
Am J Obstet Gynecol 2016 Nov;215(5):663.e1-663.e6. Epub 2016 Jun 16 doi: 10.1016/j.ajog.2016.06.012. PMID: 27319369
Trevisan C, Veronese N, Bolzetta F, De Rui M, Maggi S, Zambon S, Musacchio E, Sartori L, Perissinotto E, Crepaldi G, Manzato E, Sergi G
Rejuvenation Res 2016 Dec;19(6):447-455. Epub 2016 Mar 14 doi: 10.1089/rej.2015.1768. PMID: 26778182

Recent systematic reviews

Udow SJ, Robertson AD, MacIntosh BJ, Espay AJ, Rowe JB, Lang AE, Masellis M
J Neurol Neurosurg Psychiatry 2016 Dec;87(12):1311-1321. Epub 2016 Sep 9 doi: 10.1136/jnnp-2016-314123. PMID: 27613160
Zhuang S, Wang HF, Wang X, Li J, Xing CM
J Clin Neurosci 2016 Nov;33:32-38. Epub 2016 Jul 27 doi: 10.1016/j.jocn.2016.02.036. PMID: 27475317
Resnick B, Beaupre L, McGilton KS, Galik E, Liu W, Neuman MD, Gruber-Baldini AL, Orwig D, Magaziner J
J Am Med Dir Assoc 2016 Mar 1;17(3):200-5. Epub 2015 Nov 25 doi: 10.1016/j.jamda.2015.10.004. PMID: 26612482Free PMC Article
Kishi T, Matsunaga S, Oya K, Ikuta T, Iwata N
Int J Neuropsychopharmacol 2015 Jun 19;18(12) doi: 10.1093/ijnp/pyv070. PMID: 26091818Free PMC Article
Guo JL, Tsai YY, Liao JY, Tu HM, Huang CM
Int J Geriatr Psychiatry 2014 Jul;29(7):661-9. Epub 2013 Dec 7 doi: 10.1002/gps.4056. PMID: 24318959

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