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Leukokeratosis of buccal mucosa

MedGen UID:
900260
•Concept ID:
C4229144
•
Finding

Professional guidelines

PubMed

Management of oral potentially malignant disorders.
Kerr AR, Lodi G
Oral Dis 2021 Nov;27(8):2008-2025. Epub 2021 Oct 9 doi: 10.1111/odi.13980. PMID: 34324758
Oral potentially malignant disorders: A comprehensive review on clinical aspects and management.
Warnakulasuriya S
Oral Oncol 2020 Mar;102:104550. Epub 2020 Jan 22 doi: 10.1016/j.oraloncology.2019.104550. PMID: 31981993
Oral lichen planus - Differential diagnoses, serum autoantibodies, hematinic deficiencies, and management.
Chiang CP, Yu-Fong Chang J, Wang YP, Wu YH, Lu SY, Sun A
J Formos Med Assoc 2018 Sep;117(9):756-765. Epub 2018 Feb 19 doi: 10.1016/j.jfma.2018.01.021. PMID: 29472048

Recent clinical studies

Therapy

Clinical evaluation of photodynamic therapy for oral leukoplakia: a retrospective study of 50 patients.
Wang Y, Tang H, Wang K, Zhao Y, Xu J, Fan Y
BMC Oral Health 2024 Jan 3;24(1):9. doi: 10.1186/s12903-023-03791-5. PMID: 38172857Free PMC Article
Inhibition of mTOR signaling and clinical activity of metformin in oral premalignant lesions.
Gutkind JS, Molinolo AA, Wu X, Wang Z, Nachmanson D, Harismendy O, Alexandrov LB, Wuertz BR, Ondrey FG, Laronde D, Rock LD, Rosin M, Coffey C, Butler VD, Bengtson L, Hsu CH, Bauman JE, Hewitt SM, Cohen EE, Chow HS, Lippman SM, Szabo E
JCI Insight 2021 Sep 8;6(17) doi: 10.1172/jci.insight.147096. PMID: 34255745Free PMC Article
Frictional Keratosis, Contact Keratosis and Smokeless Tobacco Keratosis: Features of Reactive White Lesions of the Oral Mucosa.
Müller S
Head Neck Pathol 2019 Mar;13(1):16-24. Epub 2019 Jan 22 doi: 10.1007/s12105-018-0986-3. PMID: 30671762Free PMC Article
Harmful consequences of specific substances on the oral health.
Shaikh S, Aljanakh M, Al Ibrahim IK, Memon MS
J Pak Med Assoc 2018 Mar;68(3):437-443. PMID: 29540881
Systemic and topical photodynamic therapy (PDT) on oral mucosa lesions: an overview.
Di Stasio D, Romano A, Gentile C, Maio C, Lucchese A, Serpico R, Paparella R, Minervini G, Candotto V, Laino L
J Biol Regul Homeost Agents 2018 Jan-Feb;32(2 Suppl. 1):123-126. PMID: 29460529

Prognosis

Oral lichen planus and related lesions. What should we accept based on the available evidence?
González-Moles MÁ, Ramos-García P
Oral Dis 2023 Oct;29(7):2624-2637. Epub 2022 Dec 8 doi: 10.1111/odi.14438. PMID: 36371653
Management of oral potentially malignant disorders.
Kerr AR, Lodi G
Oral Dis 2021 Nov;27(8):2008-2025. Epub 2021 Oct 9 doi: 10.1111/odi.13980. PMID: 34324758
Premalignant and malignant oral mucosal lesions: Clinical and pathological findings.
Maymone MBC, Greer RO, Kesecker J, Sahitya PC, Burdine LK, Cheng AD, Maymone AC, Vashi NA
J Am Acad Dermatol 2019 Jul;81(1):59-71. Epub 2018 Nov 14 doi: 10.1016/j.jaad.2018.09.060. PMID: 30447325
Oral erythroplakia-What is it?
Holmstrup P
Oral Dis 2018 Mar;24(1-2):138-143. doi: 10.1111/odi.12709. PMID: 29480616
Proliferative verrucous leukoplakia: An update.
Munde A, Karle R
J Cancer Res Ther 2016 Apr-Jun;12(2):469-73. doi: 10.4103/0973-1482.151443. PMID: 27461595

Clinical prediction guides

American Association of Oral and Maxillofacial Surgeon's Position Paper on Oral Mucosal Dysplasia.
Carlson ER, Kademani D, Ward BB, Oreadi D
J Oral Maxillofac Surg 2023 Aug;81(8):1042-1054. Epub 2023 May 6 doi: 10.1016/j.joms.2023.04.017. PMID: 37244288
Common Oral Lesions.
Randall DA, Wilson Westmark NL, Neville BW
Am Fam Physician 2022 Apr 1;105(4):369-376. PMID: 35426641
Management of oral potentially malignant disorders.
Kerr AR, Lodi G
Oral Dis 2021 Nov;27(8):2008-2025. Epub 2021 Oct 9 doi: 10.1111/odi.13980. PMID: 34324758
Aneuploidy and loss of heterozygosity as risk markers for malignant transformation in oral mucosa.
Odell EW
Oral Dis 2021 Nov;27(8):1993-2007. Epub 2021 Feb 26 doi: 10.1111/odi.13797. PMID: 33577101
Proliferative verrucous leukoplakia: An update.
Munde A, Karle R
J Cancer Res Ther 2016 Apr-Jun;12(2):469-73. doi: 10.4103/0973-1482.151443. PMID: 27461595

Recent systematic reviews

Critical update, systematic review, and meta-analysis of oral erythroplakia as an oral potentially malignant disorder.
Lorenzo-Pouso AI, Lafuente-Ibáñez de Mendoza I, Pérez-Sayáns M, Pérez-Jardón A, Chamorro-Petronacci CM, Blanco-Carrión A, Aguirre-Urízar JM
J Oral Pathol Med 2022 Aug;51(7):585-593. Epub 2022 May 12 doi: 10.1111/jop.13304. PMID: 35488780Free PMC Article
Malignant transformation of oral proliferative verrucous leukoplakia: A systematic review and meta-analysis.
Ramos-García P, González-Moles MÁ, Mello FW, Bagan JV, Warnakulasuriya S
Oral Dis 2021 Nov;27(8):1896-1907. Epub 2021 May 19 doi: 10.1111/odi.13831. PMID: 34009718
Oral potentially malignant disorders: A comprehensive review on clinical aspects and management.
Warnakulasuriya S
Oral Oncol 2020 Mar;102:104550. Epub 2020 Jan 22 doi: 10.1016/j.oraloncology.2019.104550. PMID: 31981993
Malignant transformation of oral leukoplakia: a systematic review of observational studies.
Warnakulasuriya S, Ariyawardana A
J Oral Pathol Med 2016 Mar;45(3):155-66. Epub 2015 Jul 20 doi: 10.1111/jop.12339. PMID: 26189354
Clinical application of micronucleus test in exfoliated buccal cells: A systematic review and metanalysis.
Bolognesi C, Bonassi S, Knasmueller S, Fenech M, Bruzzone M, Lando C, Ceppi M
Mutat Res Rev Mutat Res 2015 Oct-Dec;766:20-31. Epub 2015 Aug 5 doi: 10.1016/j.mrrev.2015.07.002. PMID: 26596545

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    Practice guidelines

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