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Abnormal skin morphology

MedGen UID:
869110
Concept ID:
C4023528
Anatomical Abnormality
Synonyms: Abnormal skin structure; Abnormality of skin morphology
 
HPO: HP:0011121

Definition

Any morphological abnormality of the skin. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal skin morphology

Conditions with this feature

Nonsyndromic congenital nail disorder 3
MedGen UID:
107463
Concept ID:
C0544855
Congenital Abnormality
Any inherited isolated nail anomaly in which the cause of the disease is a mutation in the PLCD1 gene.
Tooth agenesis, selective, 3
MedGen UID:
410035
Concept ID:
C1970291
Disease or Syndrome
Selective tooth agenesis-3 (STHAG3) is an autosomal dominant disorder characterized mostly by agenesis of any or all molars, particularly the second molars. Teeth in the premolar, canine, and incisor regions may also be affected. There may be a history of missing primary teeth (Lammi et al., 2003, Kim et al., 2006). For a general phenotypic description and a discussion of genetic heterogeneity of selective tooth agenesis, see STHAG1 (106600).
Hypotrichosis 13
MedGen UID:
863053
Concept ID:
C4014616
Disease or Syndrome
Any hypotrichosis in which the cause of the disease is a mutation in the KRT71 gene.

Professional guidelines

PubMed

Dispenzieri A
Am J Hematol 2023 Dec;98(12):1934-1950. Epub 2023 Sep 21 doi: 10.1002/ajh.27081. PMID: 37732822
Dispenzieri A
Am J Hematol 2019 Jul;94(7):812-827. Epub 2019 May 23 doi: 10.1002/ajh.25495. PMID: 31012139
Saguil A, Kane S, Mercado M, Lauters R
Am Fam Physician 2017 Nov 15;96(10):656-663. PMID: 29431387

Recent clinical studies

Clinical prediction guides

Journo G, Ahuja A, Dias-Polak D, Eran Y, Bergman R, Shamay M
Front Cell Infect Microbiol 2021;11:666143. Epub 2021 Jul 9 doi: 10.3389/fcimb.2021.666143. PMID: 34307191Free PMC Article

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