U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Neonatal Vaginal Discharge

MedGen UID:
857739
Concept ID:
C3898145
Finding

Definition

Secretions which may be thin or tenacious, mucoid or glairy, grayish or milky, occasionally blood tinged, that originate in the vagina and are a consequence of the residual influence of maternal estrogen. [from NCI]

Professional guidelines

PubMed

Jung E, Romero R, Suksai M, Gotsch F, Chaemsaithong P, Erez O, Conde-Agudelo A, Gomez-Lopez N, Berry SM, Meyyazhagan A, Yoon BH
Am J Obstet Gynecol 2024 Mar;230(3S):S807-S840. Epub 2023 Mar 21 doi: 10.1016/j.ajog.2023.02.002. PMID: 38233317
Abu Shqara R, Glikman D, Jad S, Rechnitzer H, Lowenstein L, Frank Wolf M
Am J Obstet Gynecol 2023 Nov;229(5):540.e1-540.e9. Epub 2023 Jul 4 doi: 10.1016/j.ajog.2023.05.013. PMID: 38051599
Madden K, Middleton P, Cyna AM, Matthewson M, Jones L
Cochrane Database Syst Rev 2012 Nov 14;11:CD009356. doi: 10.1002/14651858.CD009356.pub2. PMID: 23152275

Recent clinical studies

Etiology

Jung E, Romero R, Suksai M, Gotsch F, Chaemsaithong P, Erez O, Conde-Agudelo A, Gomez-Lopez N, Berry SM, Meyyazhagan A, Yoon BH
Am J Obstet Gynecol 2024 Mar;230(3S):S807-S840. Epub 2023 Mar 21 doi: 10.1016/j.ajog.2023.02.002. PMID: 38233317
Pacagnella RC, Silva TV, Cecatti JG, Passini R Jr, Fanton TF, Borovac-Pinheiro A, Pereira CM, Fernandes KG, França MS, Li W, Mol BW; P5 Working Group
Obstet Gynecol 2022 Jan 1;139(1):41-51. doi: 10.1097/AOG.0000000000004634. PMID: 34856583
Sheyholislami H, Connor KL
Nutrients 2021 Jul 13;13(7) doi: 10.3390/nu13072382. PMID: 34371892Free PMC Article
Gianni ML, Bettinelli ME, Manfra P, Sorrentino G, Bezze E, Plevani L, Cavallaro G, Raffaeli G, Crippa BL, Colombo L, Morniroli D, Liotto N, Roggero P, Villamor E, Marchisio P, Mosca F
Nutrients 2019 Sep 20;11(10) doi: 10.3390/nu11102266. PMID: 31547061Free PMC Article
Brits H, Adendorff J, Huisamen D, Beukes D, Botha K, Herbst H, Joubert G
Afr J Prim Health Care Fam Med 2018 Apr 12;10(1):e1-e6. doi: 10.4102/phcfm.v10i1.1582. PMID: 29781686Free PMC Article

Diagnosis

Jung E, Romero R, Suksai M, Gotsch F, Chaemsaithong P, Erez O, Conde-Agudelo A, Gomez-Lopez N, Berry SM, Meyyazhagan A, Yoon BH
Am J Obstet Gynecol 2024 Mar;230(3S):S807-S840. Epub 2023 Mar 21 doi: 10.1016/j.ajog.2023.02.002. PMID: 38233317
Kenfack-Zanguim J, Kenmoe S, Bowo-Ngandji A, Kenfack-Momo R, Thierry Ebogo-Belobo J, Kengne-Ndé C, Serge Mbaga D, Zeuko'o Menkem E, Lontuo Fogang R, Tchatchouang S, Laure Ndzie Ondigui J, Irma Kame-Ngasse G, Nina Magoudjou-Pekam J, Roussel Takuissu G, Nkie Esemu S, Nantcho Clavela N, Barriere Fodjo A, Ndip L, Bigoga J, Megnekou R, Esemu LF
Eur J Obstet Gynecol Reprod Biol 2023 Oct;289:9-18. Epub 2023 Aug 17 doi: 10.1016/j.ejogrb.2023.08.013. PMID: 37611538
Brits H, Adendorff J, Huisamen D, Beukes D, Botha K, Herbst H, Joubert G
Afr J Prim Health Care Fam Med 2018 Apr 12;10(1):e1-e6. doi: 10.4102/phcfm.v10i1.1582. PMID: 29781686Free PMC Article
Dajani NK, Magann EF
Semin Perinatol 2014 Jun;38(4):201-4. doi: 10.1053/j.semperi.2014.04.005. PMID: 24863025
Freeman SB
J Obstet Gynecol Neonatal Nurs 1995 Oct;24(8):735-42. doi: 10.1111/j.1552-6909.1995.tb02558.x. PMID: 8551372

Therapy

Jung E, Romero R, Suksai M, Gotsch F, Chaemsaithong P, Erez O, Conde-Agudelo A, Gomez-Lopez N, Berry SM, Meyyazhagan A, Yoon BH
Am J Obstet Gynecol 2024 Mar;230(3S):S807-S840. Epub 2023 Mar 21 doi: 10.1016/j.ajog.2023.02.002. PMID: 38233317
Pacagnella RC, Silva TV, Cecatti JG, Passini R Jr, Fanton TF, Borovac-Pinheiro A, Pereira CM, Fernandes KG, França MS, Li W, Mol BW; P5 Working Group
Obstet Gynecol 2022 Jan 1;139(1):41-51. doi: 10.1097/AOG.0000000000004634. PMID: 34856583
Sheyholislami H, Connor KL
Nutrients 2021 Jul 13;13(7) doi: 10.3390/nu13072382. PMID: 34371892Free PMC Article
Gianni ML, Bettinelli ME, Manfra P, Sorrentino G, Bezze E, Plevani L, Cavallaro G, Raffaeli G, Crippa BL, Colombo L, Morniroli D, Liotto N, Roggero P, Villamor E, Marchisio P, Mosca F
Nutrients 2019 Sep 20;11(10) doi: 10.3390/nu11102266. PMID: 31547061Free PMC Article
Middleton P, Shepherd E, Crowther CA
Cochrane Database Syst Rev 2018 May 9;5(5):CD004945. doi: 10.1002/14651858.CD004945.pub4. PMID: 29741208Free PMC Article

Prognosis

Rahman M, Chen L, Daw J, Wright JD, D'Alton ME, Wen T, Friedman AM
J Matern Fetal Neonatal Med 2022 Dec;35(25):10143-10151. Epub 2022 Sep 14 doi: 10.1080/14767058.2022.2122037. PMID: 36104042
Middleton P, Shepherd E, Morris J, Crowther CA, Gomersall JC
Cochrane Database Syst Rev 2020 Jul 15;7(7):CD004945. doi: 10.1002/14651858.CD004945.pub5. PMID: 32666584Free PMC Article
Holmes N, Walker JJ, Chapple W
J Fam Pract 2019 Apr;68(3):175-177. PMID: 31039216
Middleton P, Shepherd E, Crowther CA
Cochrane Database Syst Rev 2018 May 9;5(5):CD004945. doi: 10.1002/14651858.CD004945.pub4. PMID: 29741208Free PMC Article
Locksmith G, Duff P
Semin Perinatol 2001 Oct;25(5):295-309. doi: 10.1053/sper.2001.27163. PMID: 11707017

Clinical prediction guides

Rahman M, Chen L, Daw J, Wright JD, D'Alton ME, Wen T, Friedman AM
J Matern Fetal Neonatal Med 2022 Dec;35(25):10143-10151. Epub 2022 Sep 14 doi: 10.1080/14767058.2022.2122037. PMID: 36104042
Middleton P, Shepherd E, Morris J, Crowther CA, Gomersall JC
Cochrane Database Syst Rev 2020 Jul 15;7(7):CD004945. doi: 10.1002/14651858.CD004945.pub5. PMID: 32666584Free PMC Article
Gianni ML, Bettinelli ME, Manfra P, Sorrentino G, Bezze E, Plevani L, Cavallaro G, Raffaeli G, Crippa BL, Colombo L, Morniroli D, Liotto N, Roggero P, Villamor E, Marchisio P, Mosca F
Nutrients 2019 Sep 20;11(10) doi: 10.3390/nu11102266. PMID: 31547061Free PMC Article
Middleton P, Shepherd E, Crowther CA
Cochrane Database Syst Rev 2018 May 9;5(5):CD004945. doi: 10.1002/14651858.CD004945.pub4. PMID: 29741208Free PMC Article
Boers KE, Vijgen SM, Bijlenga D, van der Post JA, Bekedam DJ, Kwee A, van der Salm PC, van Pampus MG, Spaanderman ME, de Boer K, Duvekot JJ, Bremer HA, Hasaart TH, Delemarre FM, Bloemenkamp KW, van Meir CA, Willekes C, Wijnen EJ, Rijken M, le Cessie S, Roumen FJ, Thornton JG, van Lith JM, Mol BW, Scherjon SA; DIGITAT study group
BMJ 2010 Dec 21;341:c7087. doi: 10.1136/bmj.c7087. PMID: 21177352Free PMC Article

Recent systematic reviews

Kenfack-Zanguim J, Kenmoe S, Bowo-Ngandji A, Kenfack-Momo R, Thierry Ebogo-Belobo J, Kengne-Ndé C, Serge Mbaga D, Zeuko'o Menkem E, Lontuo Fogang R, Tchatchouang S, Laure Ndzie Ondigui J, Irma Kame-Ngasse G, Nina Magoudjou-Pekam J, Roussel Takuissu G, Nkie Esemu S, Nantcho Clavela N, Barriere Fodjo A, Ndip L, Bigoga J, Megnekou R, Esemu LF
Eur J Obstet Gynecol Reprod Biol 2023 Oct;289:9-18. Epub 2023 Aug 17 doi: 10.1016/j.ejogrb.2023.08.013. PMID: 37611538
Sheyholislami H, Connor KL
Nutrients 2021 Jul 13;13(7) doi: 10.3390/nu13072382. PMID: 34371892Free PMC Article
Middleton P, Shepherd E, Morris J, Crowther CA, Gomersall JC
Cochrane Database Syst Rev 2020 Jul 15;7(7):CD004945. doi: 10.1002/14651858.CD004945.pub5. PMID: 32666584Free PMC Article
Middleton P, Shepherd E, Crowther CA
Cochrane Database Syst Rev 2018 May 9;5(5):CD004945. doi: 10.1002/14651858.CD004945.pub4. PMID: 29741208Free PMC Article
Gallos ID, Williams HM, Price MJ, Merriel A, Gee H, Lissauer D, Moorthy V, Tobias A, Deeks JJ, Widmer M, Tunçalp Ö, Gülmezoglu AM, Hofmeyr GJ, Coomarasamy A
Cochrane Database Syst Rev 2018 Apr 25;4(4):CD011689. doi: 10.1002/14651858.CD011689.pub2. PMID: 29693726Free PMC Article

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...