U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Lower urinary tract symptoms due to benign prostatic hypertrophy

MedGen UID:
843328
•Concept ID:
C3874991
•
Sign or Symptom
SNOMED CT: Lower urinary tract symptoms due to benign prostatic hypertrophy (30041000119101)

Professional guidelines

PubMed

Chronic inflammation in benign prostatic hyperplasia: Pathophysiology and treatment options.
Inamura S, Terada N
Int J Urol 2024 Sep;31(9):968-974. Epub 2024 Jun 27 doi: 10.1111/iju.15518. PMID: 38934050Free PMC Article
Management of Lower Urinary Tract Symptoms Attributed to Benign Prostatic Hyperplasia (BPH): AUA Guideline Amendment 2023.
Sandhu JS, Bixler BR, Dahm P, Goueli R, Kirkby E, Stoffel JT, Wilt TJ
J Urol 2024 Jan;211(1):11-19. Epub 2023 Sep 14 doi: 10.1097/JU.0000000000003698. PMID: 37706750
Medical Treatment of Benign Prostatic Hyperplasia.
Plochocki A, King B
Urol Clin North Am 2022 May;49(2):231-238. Epub 2022 Mar 22 doi: 10.1016/j.ucl.2021.12.003. PMID: 35428429

Recent clinical studies

Etiology

Lower Urinary Tract Symptoms in Men: A Review.
Wei JT, Dauw CA, Brodsky CN
JAMA 2025 Sep 2;334(9):809-821. doi: 10.1001/jama.2025.7045. PMID: 40658396
Benign prostatic hyperplasia.
Infante Hernández S, Gómez Rivas J, Moreno Sierra J
Med Clin (Barc) 2024 Oct 25;163(8):407-414. Epub 2024 Jul 15 doi: 10.1016/j.medcli.2024.04.014. PMID: 39013719
Benign Prostatic Hyperplasia: Rapid Evidence Review.
Arnold MJ, Gaillardetz A, Ohiokpehai J
Am Fam Physician 2023 Jun;107(6):613-622. PMID: 37327163
Benign prostatic hyperplasia.
Chughtai B, Forde JC, Thomas DD, Laor L, Hossack T, Woo HH, Te AE, Kaplan SA
Nat Rev Dis Primers 2016 May 5;2:16031. doi: 10.1038/nrdp.2016.31. PMID: 27147135
Benign prostatic hyperplasia: epidemiology, economics and evaluation.
Vuichoud C, Loughlin KR
Can J Urol 2015 Oct;22 Suppl 1:1-6. PMID: 26497338

Diagnosis

Benign prostatic hyperplasia.
Infante Hernández S, Gómez Rivas J, Moreno Sierra J
Med Clin (Barc) 2024 Oct 25;163(8):407-414. Epub 2024 Jul 15 doi: 10.1016/j.medcli.2024.04.014. PMID: 39013719
Management of Lower Urinary Tract Symptoms Attributed to Benign Prostatic Hyperplasia: AUA GUIDELINE PART I-Initial Work-up and Medical Management.
Lerner LB, McVary KT, Barry MJ, Bixler BR, Dahm P, Das AK, Gandhi MC, Kaplan SA, Kohler TS, Martin L, Parsons JK, Roehrborn CG, Stoffel JT, Welliver C, Wilt TJ
J Urol 2021 Oct;206(4):806-817. Epub 2021 Aug 13 doi: 10.1097/JU.0000000000002183. PMID: 34384237
Benign Prostatic Hyperplasia.
Langan RC
Prim Care 2019 Jun;46(2):223-232. Epub 2019 Apr 1 doi: 10.1016/j.pop.2019.02.003. PMID: 31030823
Benign prostatic hyperplasia.
Chughtai B, Forde JC, Thomas DD, Laor L, Hossack T, Woo HH, Te AE, Kaplan SA
Nat Rev Dis Primers 2016 May 5;2:16031. doi: 10.1038/nrdp.2016.31. PMID: 27147135
Management of Benign Prostatic Hyperplasia.
Kim EH, Larson JA, Andriole GL
Annu Rev Med 2016;67:137-51. Epub 2015 Sep 2 doi: 10.1146/annurev-med-063014-123902. PMID: 26331999

Therapy

Chronic inflammation in benign prostatic hyperplasia: Pathophysiology and treatment options.
Inamura S, Terada N
Int J Urol 2024 Sep;31(9):968-974. Epub 2024 Jun 27 doi: 10.1111/iju.15518. PMID: 38934050Free PMC Article
Management of Lower Urinary Tract Symptoms Attributed to Benign Prostatic Hyperplasia: AUA GUIDELINE PART I-Initial Work-up and Medical Management.
Lerner LB, McVary KT, Barry MJ, Bixler BR, Dahm P, Das AK, Gandhi MC, Kaplan SA, Kohler TS, Martin L, Parsons JK, Roehrborn CG, Stoffel JT, Welliver C, Wilt TJ
J Urol 2021 Oct;206(4):806-817. Epub 2021 Aug 13 doi: 10.1097/JU.0000000000002183. PMID: 34384237
Benign Prostatic Hyperplasia.
Langan RC
Prim Care 2019 Jun;46(2):223-232. Epub 2019 Apr 1 doi: 10.1016/j.pop.2019.02.003. PMID: 31030823
Pathophysiology of Benign Prostatic Hyperplasia and Benign Prostatic Enlargement: A Mini-Review.
Madersbacher S, Sampson N, Culig Z
Gerontology 2019;65(5):458-464. Epub 2019 Apr 3 doi: 10.1159/000496289. PMID: 30943489
Management of Benign Prostatic Hyperplasia.
Kim EH, Larson JA, Andriole GL
Annu Rev Med 2016;67:137-51. Epub 2015 Sep 2 doi: 10.1146/annurev-med-063014-123902. PMID: 26331999

Prognosis

Final 5-Year Outcomes of the Multicenter Randomized Sham-Controlled Trial of a Water Vapor Thermal Therapy for Treatment of Moderate to Severe Lower Urinary Tract Symptoms Secondary to Benign Prostatic Hyperplasia.
McVary KT, Gittelman MC, Goldberg KA, Patel K, Shore ND, Levin RM, Pliskin M, Beahrs JR, Prall D, Kaminetsky J, Cowan BE, Cantrill CH, Mynderse LA, Ulchaker JC, Tadros NN, Gange SN, Roehrborn CG
J Urol 2021 Sep;206(3):715-724. Epub 2021 Apr 19 doi: 10.1097/JU.0000000000001778. PMID: 33872051
Lifestyle in urology: Benign diseases.
Bientinesi R, Gandi C, Vaccarella L, Sacco E
Urologia 2021 Aug;88(3):163-174. Epub 2021 Feb 12 doi: 10.1177/0391560321994386. PMID: 33579177
Five year results of the prospective randomized controlled prostatic urethral L.I.F.T. study.
Roehrborn CG, Barkin J, Gange SN, Shore ND, Giddens JL, Bolton DM, Cowan BE, Cantwell AL, McVary KT, Te AE, Gholami SS, Moseley WG, Chin PT, Dowling WT, Freedman SJ, Incze PF, Coffield KS, Herron S, Rashid P, Rukstalis DB
Can J Urol 2017 Jun;24(3):8802-8813. PMID: 28646935
The Epidemiology of Benign Prostatic Hyperplasia Associated with Lower Urinary Tract Symptoms: Prevalence and Incident Rates.
Egan KB
Urol Clin North Am 2016 Aug;43(3):289-97. doi: 10.1016/j.ucl.2016.04.001. PMID: 27476122
Benign prostatic hyperplasia: epidemiology, economics and evaluation.
Vuichoud C, Loughlin KR
Can J Urol 2015 Oct;22 Suppl 1:1-6. PMID: 26497338

Clinical prediction guides

Lower Urinary Tract Symptoms in Men: A Review.
Wei JT, Dauw CA, Brodsky CN
JAMA 2025 Sep 2;334(9):809-821. doi: 10.1001/jama.2025.7045. PMID: 40658396
Benign Prostatic Hyperplasia: Rapid Evidence Review.
Arnold MJ, Gaillardetz A, Ohiokpehai J
Am Fam Physician 2023 Jun;107(6):613-622. PMID: 37327163
Final 5-Year Outcomes of the Multicenter Randomized Sham-Controlled Trial of a Water Vapor Thermal Therapy for Treatment of Moderate to Severe Lower Urinary Tract Symptoms Secondary to Benign Prostatic Hyperplasia.
McVary KT, Gittelman MC, Goldberg KA, Patel K, Shore ND, Levin RM, Pliskin M, Beahrs JR, Prall D, Kaminetsky J, Cowan BE, Cantrill CH, Mynderse LA, Ulchaker JC, Tadros NN, Gange SN, Roehrborn CG
J Urol 2021 Sep;206(3):715-724. Epub 2021 Apr 19 doi: 10.1097/JU.0000000000001778. PMID: 33872051
Aquablation for BPH.
Kasraeian A, Alcantara M, Alcantara KM, Altamirando JA, Kasraeian A
Can J Urol 2020 Oct;27(5):10378-10381. PMID: 33049190
Rezūm Water Vapor Thermal Therapy for Lower Urinary Tract Symptoms Associated With Benign Prostatic Hyperplasia: 4-Year Results From Randomized Controlled Study.
McVary KT, Rogers T, Roehrborn CG
Urology 2019 Apr;126:171-179. Epub 2019 Jan 21 doi: 10.1016/j.urology.2018.12.041. PMID: 30677455

Recent systematic reviews

Safety and efficacy of an α(1) -blocker plus mirabegron compared with an α(1) -blocker plus antimuscarinic in men with lower urinary tract symptoms secondary to benign prostatic hyperplasia and overactive bladder: A systematic review and network meta-analysis.
Herschorn S, Tarcan T, Jiang YH, Chung E, Abdul Hadi F, Steup A, Sumarsono B
Neurourol Urodyn 2024 Mar;43(3):604-619. Epub 2024 Jan 30 doi: 10.1002/nau.25399. PMID: 38291827
Conservative interventions for managing urinary incontinence after prostate surgery.
Johnson EE, Mamoulakis C, Stoniute A, Omar MI, Sinha S
Cochrane Database Syst Rev 2023 Apr 18;4(4):CD014799. doi: 10.1002/14651858.CD014799.pub2. PMID: 37070660Free PMC Article
Minimally Invasive Treatments for Benign Prostatic Obstruction: A Systematic Review and Network Meta-analysis.
Cornu JN, Zantek P, Burtt G, Martin C, Martin A, Springate C, Chughtai B
Eur Urol 2023 Jun;83(6):534-547. Epub 2023 Mar 22 doi: 10.1016/j.eururo.2023.02.028. PMID: 36964042
Minimally invasive treatments for lower urinary tract symptoms in men with benign prostatic hyperplasia: a network meta-analysis.
Franco JV, Jung JH, Imamura M, Borofsky M, Omar MI, Escobar Liquitay CM, Young S, Golzarian J, Veroniki AA, Garegnani L, Dahm P
Cochrane Database Syst Rev 2021 Jul 15;7(7):CD013656. doi: 10.1002/14651858.CD013656.pub2. PMID: 34693990Free PMC Article
Benign prostatic hyperplasia: epidemiology, economics and evaluation.
Vuichoud C, Loughlin KR
Can J Urol 2015 Oct;22 Suppl 1:1-6. PMID: 26497338

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...