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Purulent discharge

MedGen UID:
83072
•Concept ID:
C0333274
•
Sign or Symptom
Synonym: Purulent Discharge
SNOMED CT: Purulent discharge (35013009)

Definition

Pus-containing fluid that is draining from an orifice or wound. [from NCI]

Professional guidelines

PubMed

Early postoperative outcomes of sinus laser closure versus crystallized phenol treatment for pilonidal sinus disease: a retrospective comparative study.
Yildirak MK, Demırpolat MT
Tech Coloproctol 2026 Jun 3;30(1) doi: 10.1007/s10151-026-03345-1. PMID: 42237035Free PMC Article
Assessment of Treatment Effectiveness in Acute and Chronic Anal Fissures.
Dinçer Oİ, Felek D, Cakmak E, Turksoy VA
Medicina (Kaunas) 2026 Mar 5;62(3) doi: 10.3390/medicina62030490. PMID: 41901571Free PMC Article
Surgical treatment outcomes and prognostic factors in mandibular medication-related osteonecrosis of the jaw.
Chen J, Jia K, Lyu X, An J
Int J Oral Maxillofac Surg 2026 Aug;55(8):913-919. Epub 2026 Feb 18 doi: 10.1016/j.ijom.2026.02.001. PMID: 41714247

Recent clinical studies

Etiology

Case Report: Triple-negative metaplastic breast carcinoma with primary resistance to neoadjuvant chemoimmunotherapy, refractory tumor necrosis-related fever, and rapid postoperative disease progression.
Hu L, Luo Y, Luo J
Front Oncol 2026;16:1943838. Epub 2026 Sep 17 doi: 10.3389/fonc.2026.1943838. PMID: 42823980Free PMC Article
Impact of a 12-Element Nurse-Led Tracheostomy Care Bundle on Stoma Integrity, Respiratory Distress and Suspected Pneumonia-Related Outcomes Among Patients With Tracheostomies: A Quasi-Experimental Study.
Hammouda EY, Zaky ME, Ahmed MSA, Zahran WE, Mansour HE
Nurs Open 2026 Oct;13(10):e70861. doi: 10.1002/nop2.70861. PMID: 42813890Free PMC Article
Clinical and Epidemiological Characteristics of Retrospective Single-Center Observational Study.
Andrei EC, Liliac IM, Boldeanu G, Busuioc CJ, Pătru L, Țuculina MJ, Bușu OV, Iacov CA, Pătru CL, Munteanu CM
J Clin Med 2026 Sep 8;15(18) doi: 10.3390/jcm15186960. PMID: 42795733Free PMC Article
Reversible acute-on-chronic kidney injury complicating antibiotic dosing in group A streptococcal necrotizing fasciitis at a remote Indonesian hospital: a case report.
Septiawan ZA, Nirvana NAD, Kasman I, Setiawan IKA
J Surg Case Rep 2026 Sep;2026(9):rjag808. Epub 2026 Sep 20 doi: 10.1093/jscr/rjag808. PMID: 42764878Free PMC Article
Arthroscopic treatment of septic arthritis of the metacarpophalangeal joint: Case report and technical description.
Kaempf R, Carratalá V, Fischer P, Delgado PJ
J Hand Microsurg 2026 Nov;18(6):100510. Epub 2026 Sep 7 doi: 10.1016/j.jham.2026.100510. PMID: 42751064Free PMC Article

Diagnosis

Case Report: Triple-negative metaplastic breast carcinoma with primary resistance to neoadjuvant chemoimmunotherapy, refractory tumor necrosis-related fever, and rapid postoperative disease progression.
Hu L, Luo Y, Luo J
Front Oncol 2026;16:1943838. Epub 2026 Sep 17 doi: 10.3389/fonc.2026.1943838. PMID: 42823980Free PMC Article
Squamous Cell Carcinoma Arising from Chronic Osteomyelitis: A Single-Center Case Series of Six Patients.
Li H, Chen J, Li D, Tan Q, Ruan H, Han P, Chen X
Infect Drug Resist 2026;19:632466. Epub 2026 Sep 18 doi: 10.2147/IDR.S632466. PMID: 42774979Free PMC Article
EVT-Inspired Simplified Negative-Pressure Nasoesophageal Drainage for Cervical Abscess Secondary to Esophageal Perforation.
Yi L, Zheng L, Huang Z, Yang Y
Am J Case Rep 2026 Sep 21;27:e953266. doi: 10.12659/AJCR.953266. PMID: 42766486Free PMC Article
Atypical Presentation of Undiagnosed Crouzon's Syndrome With Pansinusitis, Orbital Cellulitis, and Altered Mentation Successfully Managed With Functional Endoscopic Sinus Surgery: A Case Report.
Issar P, Galav S, Goel R, Bhushan A
Case Rep Crit Care 2026;2026:8887878. Epub 2026 Sep 12 doi: 10.1155/crcc/8887878. PMID: 42732256Free PMC Article
Pediatric intraorbital wooden foreign body mimicking an orbital mass: Delayed diagnosis and imaging considerations on MRI.
Ayene H, Belachew B, Worke AB, Altamo E, Sime A, Girma T
Radiol Case Rep 2026 Nov;21(11):5341-5345. Epub 2026 Aug 13 doi: 10.1016/j.radcr.2026.07.042. PMID: 42633134Free PMC Article

Therapy

Impact of a 12-Element Nurse-Led Tracheostomy Care Bundle on Stoma Integrity, Respiratory Distress and Suspected Pneumonia-Related Outcomes Among Patients With Tracheostomies: A Quasi-Experimental Study.
Hammouda EY, Zaky ME, Ahmed MSA, Zahran WE, Mansour HE
Nurs Open 2026 Oct;13(10):e70861. doi: 10.1002/nop2.70861. PMID: 42813890Free PMC Article
Recurrent Intravenous Contrast-Induced Submandibular Sialadenitis: A Case Report and Literature Review.
Chobaroon N, Suwatanapongched T
Am J Case Rep 2026 Sep 12;27:e953439. doi: 10.12659/AJCR.953439. PMID: 42728730Free PMC Article
Standardized Lacrimal Sac Massage vs Probing for Congenital Nasolacrimal Duct Obstruction in Infants: A Noninferiority Randomized Trial.
Zheng X, Yu X, Wu G, Zhang J, Wang K, Jin L, Huang S, Chen R, Yu H, Huang W, Li Z, Liang X
JAMA Ophthalmol 2026 Sep 1;144(9):847-853. doi: 10.1001/jamaophthalmol.2026.3169. PMID: 42593819Free PMC Article
Synchronous rectal cancer and extranodal NK/T-cell lymphoma, nasal type: A case report.
Wang G, Li W, Sun B, Tong M
Medicine (Baltimore) 2026 Jul 17;105(29):e49775. doi: 10.1097/MD.0000000000049775. PMID: 42470035Free PMC Article
Epidemiology of civilian patients with acute conflict-related extremity injuries sustained in Syria and Iraq.
Bengtson D, Haweizy R, Bashaireh K, Malmstedt J, Älgå A
PLOS Glob Public Health 2026;6(7):e0006627. Epub 2026 Jul 10 doi: 10.1371/journal.pgph.0006627. PMID: 42430328Free PMC Article

Prognosis

Case Report: Fournier's gangrene occurring in the setting of intestinal obstruction complicated by suspected intra-abdominal infection, successfully managed with repeated surgical debridement.
Wu T, Hu N, Ma Y
Front Surg 2026;13:1890179. Epub 2026 Sep 4 doi: 10.3389/fsurg.2026.1890179. PMID: 42761041Free PMC Article
Kerion, an often missed scalp lesion: A case report.
Suriani S, Nazatul Shima AR
Malays Fam Physician 2026;21:41. Epub 2026 Aug 18 doi: 10.51866/cr.719. PMID: 42757270Free PMC Article
Arthroscopic treatment of septic arthritis of the metacarpophalangeal joint: Case report and technical description.
Kaempf R, Carratalá V, Fischer P, Delgado PJ
J Hand Microsurg 2026 Nov;18(6):100510. Epub 2026 Sep 7 doi: 10.1016/j.jham.2026.100510. PMID: 42751064Free PMC Article
Standardized Lacrimal Sac Massage vs Probing for Congenital Nasolacrimal Duct Obstruction in Infants: A Noninferiority Randomized Trial.
Zheng X, Yu X, Wu G, Zhang J, Wang K, Jin L, Huang S, Chen R, Yu H, Huang W, Li Z, Liang X
JAMA Ophthalmol 2026 Sep 1;144(9):847-853. doi: 10.1001/jamaophthalmol.2026.3169. PMID: 42593819Free PMC Article
Sustained response to rituximab in an ANCA-negative necrotizing vasculitis with initial detection of Corynebacterium kroppenstedtii.
Al-Azem N, Knothe A, Raguse JD, Nierkamp I, Beule AG, Rudack C, Müller F, Kerlikowki A, Wardelmann E, Pavenstädt H, Kriegel MA, Hasseli R
Clin Transl Immunology 2026;15(8):e70119. Epub 2026 Aug 11 doi: 10.1002/cti2.70119. PMID: 42582765Free PMC Article

Clinical prediction guides

Impact of a 12-Element Nurse-Led Tracheostomy Care Bundle on Stoma Integrity, Respiratory Distress and Suspected Pneumonia-Related Outcomes Among Patients With Tracheostomies: A Quasi-Experimental Study.
Hammouda EY, Zaky ME, Ahmed MSA, Zahran WE, Mansour HE
Nurs Open 2026 Oct;13(10):e70861. doi: 10.1002/nop2.70861. PMID: 42813890Free PMC Article
Conjunctival reactive cutaneous capillary endothelial proliferation induced by camrelizumab in an esophageal cancer patient: a case report and literature review.
Wei Y, Zan Y, Zhang J, Wang Q, Xu Y, Si J, Lv R
Front Oncol 2026;16:1847562. Epub 2026 Sep 11 doi: 10.3389/fonc.2026.1847562. PMID: 42798342Free PMC Article
Squamous Cell Carcinoma Arising from Chronic Osteomyelitis: A Single-Center Case Series of Six Patients.
Li H, Chen J, Li D, Tan Q, Ruan H, Han P, Chen X
Infect Drug Resist 2026;19:632466. Epub 2026 Sep 18 doi: 10.2147/IDR.S632466. PMID: 42774979Free PMC Article
Arthroscopic treatment of septic arthritis of the metacarpophalangeal joint: Case report and technical description.
Kaempf R, Carratalá V, Fischer P, Delgado PJ
J Hand Microsurg 2026 Nov;18(6):100510. Epub 2026 Sep 7 doi: 10.1016/j.jham.2026.100510. PMID: 42751064Free PMC Article
Recurrent Intravenous Contrast-Induced Submandibular Sialadenitis: A Case Report and Literature Review.
Chobaroon N, Suwatanapongched T
Am J Case Rep 2026 Sep 12;27:e953439. doi: 10.12659/AJCR.953439. PMID: 42728730Free PMC Article

Recent systematic reviews

Diagnosis and treatment for anal fistula: a systematic review of clinical practice guidelines and consensus statements.
Lu MY, Wang J, Wang ZC, Cai ZL, Liang N, Shi R
Front Surg 2025;12:1566130. Epub 2025 Jul 2 doi: 10.3389/fsurg.2025.1566130. PMID: 40672439Free PMC Article
Urethrocavernous fistula: a case report and systematic review.
Fernández Siles J, Correa Portillo S, España Navarro R
Rev Int Androl 2025 Mar;23(1):102-107. Epub 2025 Mar 30 doi: 10.22514/j.androl.2025.012. PMID: 40350683
Potential efficacy and safety of Xiyanping injection as adjuvant therapy in treatment of suppurative acute tonsillitis: a meta-analysis, trial sequential analysis, and certainty of evidence.
Cheng FJ, Lyu J, Wang LX, Xie YM
Front Pharmacol 2024;15:1327856. Epub 2024 Jun 12 doi: 10.3389/fphar.2024.1327856. PMID: 38933666Free PMC Article
Systematic Review of Heel Puncture-Related Osteomyelitis of the Calcaneus in Newborn Infants.
Martin VT, Dhagey IA, Wu H, Xu S, Yu B
Infect Dis Ther 2024 May;13(5):991-1004. Epub 2024 Apr 8 doi: 10.1007/s40121-024-00957-8. PMID: 38589762Free PMC Article
The Effect of Platelet-Rich Plasma on Healing Time in Patients Following Pilonidal Sinus Surgery: A Systematic Review.
Khan QI, Baig H, Al Failakawi A, Majeed S, Khan M, Lucocq J
Cureus 2022 Aug;14(8):e27777. Epub 2022 Aug 8 doi: 10.7759/cureus.27777. PMID: 36106230Free PMC Article

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