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Metastatic melanoma

MedGen UID:
83002
Concept ID:
C0278883
Neoplastic Process
Synonyms: metastatic malignant melanoma; Metastatic Melanoma; metastatic melanoma
 
Monarch Initiative: MONDO:0005191

Definition

A melanoma that has spread from its primary site to another anatomic site. Melanomas frequently metastasize to lymph nodes, liver, lungs, and brain. [from NCI]

Professional guidelines

PubMed

Jenkins RW, Fisher DE
J Invest Dermatol 2021 Jan;141(1):23-31. Epub 2020 Apr 5 doi: 10.1016/j.jid.2020.03.943. PMID: 32268150Free PMC Article
Ralli M, Botticelli A, Visconti IC, Angeletti D, Fiore M, Marchetti P, Lambiase A, de Vincentiis M, Greco A
J Immunol Res 2020;2020:9235638. Epub 2020 Jun 28 doi: 10.1155/2020/9235638. PMID: 32671117Free PMC Article
Davis LE, Shalin SC, Tackett AJ
Cancer Biol Ther 2019;20(11):1366-1379. Epub 2019 Aug 1 doi: 10.1080/15384047.2019.1640032. PMID: 31366280Free PMC Article

Recent clinical studies

Etiology

van den Berg JH, Heemskerk B, van Rooij N, Gomez-Eerland R, Michels S, van Zon M, de Boer R, Bakker NAM, Jorritsma-Smit A, van Buuren MM, Kvistborg P, Spits H, Schotte R, Mallo H, Karger M, van der Hage JA, Wouters MWJM, Pronk LM, Geukes Foppen MH, Blank CU, Beijnen JH, Nuijen B, Schumacher TN, Haanen JBAG
J Immunother Cancer 2020 Aug;8(2) doi: 10.1136/jitc-2020-000848. PMID: 32753545Free PMC Article
Pavri SN, Clune J, Ariyan S, Narayan D
Plast Reconstr Surg 2016 Aug;138(2):330e-340e. doi: 10.1097/PRS.0000000000002367. PMID: 27465194
Snyder A, Zamarin D, Wolchok JD
Prog Tumor Res 2015;42:22-9. Epub 2015 Sep 4 doi: 10.1159/000436998. PMID: 26376963
Robert C, Thomas L, Bondarenko I, O'Day S, Weber J, Garbe C, Lebbe C, Baurain JF, Testori A, Grob JJ, Davidson N, Richards J, Maio M, Hauschild A, Miller WH Jr, Gascon P, Lotem M, Harmankaya K, Ibrahim R, Francis S, Chen TT, Humphrey R, Hoos A, Wolchok JD
N Engl J Med 2011 Jun 30;364(26):2517-26. Epub 2011 Jun 5 doi: 10.1056/NEJMoa1104621. PMID: 21639810
Hodi FS, O'Day SJ, McDermott DF, Weber RW, Sosman JA, Haanen JB, Gonzalez R, Robert C, Schadendorf D, Hassel JC, Akerley W, van den Eertwegh AJ, Lutzky J, Lorigan P, Vaubel JM, Linette GP, Hogg D, Ottensmeier CH, Lebbé C, Peschel C, Quirt I, Clark JI, Wolchok JD, Weber JS, Tian J, Yellin MJ, Nichol GM, Hoos A, Urba WJ
N Engl J Med 2010 Aug 19;363(8):711-23. Epub 2010 Jun 5 doi: 10.1056/NEJMoa1003466. PMID: 20525992Free PMC Article

Diagnosis

Lowe L
Pathology 2023 Mar;55(2):236-244. Epub 2022 Dec 21 doi: 10.1016/j.pathol.2022.11.006. PMID: 36641376
Switzer B, Puzanov I, Skitzki JJ, Hamad L, Ernstoff MS
JCO Oncol Pract 2022 May;18(5):335-351. Epub 2022 Feb 8 doi: 10.1200/OP.21.00686. PMID: 35133862Free PMC Article
Davis LE, Shalin SC, Tackett AJ
Cancer Biol Ther 2019;20(11):1366-1379. Epub 2019 Aug 1 doi: 10.1080/15384047.2019.1640032. PMID: 31366280Free PMC Article
Chapman PB
Am Soc Clin Oncol Educ Book 2014:16-9. doi: 10.14694/EdBook_AM.2014.34.16. PMID: 24857055
Larkin J, Gore M
BMJ Clin Evid 2008 Aug 22;2008 PMID: 19445806Free PMC Article

Therapy

van den Berg JH, Heemskerk B, van Rooij N, Gomez-Eerland R, Michels S, van Zon M, de Boer R, Bakker NAM, Jorritsma-Smit A, van Buuren MM, Kvistborg P, Spits H, Schotte R, Mallo H, Karger M, van der Hage JA, Wouters MWJM, Pronk LM, Geukes Foppen MH, Blank CU, Beijnen JH, Nuijen B, Schumacher TN, Haanen JBAG
J Immunother Cancer 2020 Aug;8(2) doi: 10.1136/jitc-2020-000848. PMID: 32753545Free PMC Article
Rotte A
J Exp Clin Cancer Res 2019 Jun 13;38(1):255. doi: 10.1186/s13046-019-1259-z. PMID: 31196207Free PMC Article
Signorelli J, Shah Gandhi A
Ann Pharmacother 2017 Feb;51(2):146-153. Epub 2016 Oct 4 doi: 10.1177/1060028016672037. PMID: 27701080
Larkin J, Chiarion-Sileni V, Gonzalez R, Grob JJ, Cowey CL, Lao CD, Schadendorf D, Dummer R, Smylie M, Rutkowski P, Ferrucci PF, Hill A, Wagstaff J, Carlino MS, Haanen JB, Maio M, Marquez-Rodas I, McArthur GA, Ascierto PA, Long GV, Callahan MK, Postow MA, Grossmann K, Sznol M, Dreno B, Bastholt L, Yang A, Rollin LM, Horak C, Hodi FS, Wolchok JD
N Engl J Med 2015 Jul 2;373(1):23-34. Epub 2015 May 31 doi: 10.1056/NEJMoa1504030. PMID: 26027431Free PMC Article
Russell SJ, Peng KW, Bell JC
Nat Biotechnol 2012 Jul 10;30(7):658-70. doi: 10.1038/nbt.2287. PMID: 22781695Free PMC Article

Prognosis

van den Berg JH, Heemskerk B, van Rooij N, Gomez-Eerland R, Michels S, van Zon M, de Boer R, Bakker NAM, Jorritsma-Smit A, van Buuren MM, Kvistborg P, Spits H, Schotte R, Mallo H, Karger M, van der Hage JA, Wouters MWJM, Pronk LM, Geukes Foppen MH, Blank CU, Beijnen JH, Nuijen B, Schumacher TN, Haanen JBAG
J Immunother Cancer 2020 Aug;8(2) doi: 10.1136/jitc-2020-000848. PMID: 32753545Free PMC Article
Robert C, Grob JJ, Stroyakovskiy D, Karaszewska B, Hauschild A, Levchenko E, Chiarion Sileni V, Schachter J, Garbe C, Bondarenko I, Gogas H, Mandalá M, Haanen JBAG, Lebbé C, Mackiewicz A, Rutkowski P, Nathan PD, Ribas A, Davies MA, Flaherty KT, Burgess P, Tan M, Gasal E, Voi M, Schadendorf D, Long GV
N Engl J Med 2019 Aug 15;381(7):626-636. Epub 2019 Jun 4 doi: 10.1056/NEJMoa1904059. PMID: 31166680
Turner N, Ware O, Bosenberg M
Clin Exp Metastasis 2018 Aug;35(5-6):379-391. Epub 2018 May 2 doi: 10.1007/s10585-018-9893-y. PMID: 29722002
Eggermont AM, Spatz A, Robert C
Lancet 2014 Mar 1;383(9919):816-27. Epub 2013 Sep 19 doi: 10.1016/S0140-6736(13)60802-8. PMID: 24054424
Cummins DL, Cummins JM, Pantle H, Silverman MA, Leonard AL, Chanmugam A
Mayo Clin Proc 2006 Apr;81(4):500-7. doi: 10.4065/81.4.500. PMID: 16610570

Clinical prediction guides

Proffer SL, Guo R, Demer AM, Peters MS
Hum Pathol 2023 Nov;141:110-117. Epub 2023 Aug 12 doi: 10.1016/j.humpath.2023.08.001. PMID: 37574050
Jansen Y, van der Veldt AAM, Awada G, Neyns B
Curr Oncol Rep 2022 Jul;24(7):905-915. Epub 2022 Mar 26 doi: 10.1007/s11912-022-01264-6. PMID: 35347590
Serratì S, Guida M, Di Fonte R, De Summa S, Strippoli S, Iacobazzi RM, Quarta A, De Risi I, Guida G, Paradiso A, Porcelli L, Azzariti A
Mol Cancer 2022 Jan 18;21(1):20. doi: 10.1186/s12943-021-01490-9. PMID: 35042524Free PMC Article
Larkin J, Gore M
BMJ Clin Evid 2008 Aug 22;2008 PMID: 19445806Free PMC Article
Rosenberg SA, Packard BS, Aebersold PM, Solomon D, Topalian SL, Toy ST, Simon P, Lotze MT, Yang JC, Seipp CA
N Engl J Med 1988 Dec 22;319(25):1676-80. doi: 10.1056/NEJM198812223192527. PMID: 3264384

Recent systematic reviews

Raeber ME, Sahin D, Karakus U, Boyman O
EBioMedicine 2023 Apr;90:104539. Epub 2023 Mar 31 doi: 10.1016/j.ebiom.2023.104539. PMID: 37004361Free PMC Article
Hussaini S, Chehade R, Boldt RG, Raphael J, Blanchette P, Maleki Vareki S, Fernandes R
Cancer Treat Rev 2021 Jan;92:102134. Epub 2020 Dec 3 doi: 10.1016/j.ctrv.2020.102134. PMID: 33302134
Peeraphatdit TB, Wang J, Odenwald MA, Hu S, Hart J, Charlton MR
Hepatology 2020 Jul;72(1):315-329. doi: 10.1002/hep.31227. PMID: 32167613
Safa H, Johnson DH, Trinh VA, Rodgers TE, Lin H, Suarez-Almazor ME, Fa'ak F, Saberian C, Yee C, Davies MA, Tummala S, Woodman K, Abdel-Wahab N, Diab A
J Immunother Cancer 2019 Nov 21;7(1):319. doi: 10.1186/s40425-019-0774-y. PMID: 31753014Free PMC Article
Dafni U, Michielin O, Lluesma SM, Tsourti Z, Polydoropoulou V, Karlis D, Besser MJ, Haanen J, Svane IM, Ohashi PS, Kammula US, Orcurto A, Zimmermann S, Trueb L, Klebanoff CA, Lotze MT, Kandalaft LE, Coukos G
Ann Oncol 2019 Dec 1;30(12):1902-1913. doi: 10.1093/annonc/mdz398. PMID: 31566658

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