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Pentaplegic cerebral palsy

MedGen UID:
824628
Concept ID:
C3838782
Disease or Syndrome
SNOMED CT: Pentaplegic cerebral palsy (702321005)

Definition

A form of spastic cerebral palsy affecting all four limbs with neck and head paralysis, often accompanied by eating and breathing complications. [from SNOMEDCT_US]

Professional guidelines

PubMed

Patricios JS, Schneider KJ, Dvorak J, Ahmed OH, Blauwet C, Cantu RC, Davis GA, Echemendia RJ, Makdissi M, McNamee M, Broglio S, Emery CA, Feddermann-Demont N, Fuller GW, Giza CC, Guskiewicz KM, Hainline B, Iverson GL, Kutcher JS, Leddy JJ, Maddocks D, Manley G, McCrea M, Purcell LK, Putukian M, Sato H, Tuominen MP, Turner M, Yeates KO, Herring SA, Meeuwisse W
Br J Sports Med 2023 Jun;57(11):695-711. doi: 10.1136/bjsports-2023-106898. PMID: 37316210
Jackman M, Sakzewski L, Morgan C, Boyd RN, Brennan SE, Langdon K, Toovey RAM, Greaves S, Thorley M, Novak I
Dev Med Child Neurol 2022 May;64(5):536-549. Epub 2021 Sep 21 doi: 10.1111/dmcn.15055. PMID: 34549424
Novak I, Morgan C, Adde L, Blackman J, Boyd RN, Brunstrom-Hernandez J, Cioni G, Damiano D, Darrah J, Eliasson AC, de Vries LS, Einspieler C, Fahey M, Fehlings D, Ferriero DM, Fetters L, Fiori S, Forssberg H, Gordon AM, Greaves S, Guzzetta A, Hadders-Algra M, Harbourne R, Kakooza-Mwesige A, Karlsson P, Krumlinde-Sundholm L, Latal B, Loughran-Fowlds A, Maitre N, McIntyre S, Noritz G, Pennington L, Romeo DM, Shepherd R, Spittle AJ, Thornton M, Valentine J, Walker K, White R, Badawi N
JAMA Pediatr 2017 Sep 1;171(9):897-907. doi: 10.1001/jamapediatrics.2017.1689. PMID: 28715518Free PMC Article

Recent clinical studies

Etiology

Paul S, Nahar A, Bhagawati M, Kunwar AJ
Oxid Med Cell Longev 2022;2022:2622310. Epub 2022 Jul 30 doi: 10.1155/2022/2622310. PMID: 35941906Free PMC Article
Michael-Asalu A, Taylor G, Campbell H, Lelea LL, Kirby RS
Adv Pediatr 2019 Aug;66:189-208. Epub 2019 May 15 doi: 10.1016/j.yapd.2019.04.002. PMID: 31230694
Novak I, Morgan C, Adde L, Blackman J, Boyd RN, Brunstrom-Hernandez J, Cioni G, Damiano D, Darrah J, Eliasson AC, de Vries LS, Einspieler C, Fahey M, Fehlings D, Ferriero DM, Fetters L, Fiori S, Forssberg H, Gordon AM, Greaves S, Guzzetta A, Hadders-Algra M, Harbourne R, Kakooza-Mwesige A, Karlsson P, Krumlinde-Sundholm L, Latal B, Loughran-Fowlds A, Maitre N, McIntyre S, Noritz G, Pennington L, Romeo DM, Shepherd R, Spittle AJ, Thornton M, Valentine J, Walker K, White R, Badawi N
JAMA Pediatr 2017 Sep 1;171(9):897-907. doi: 10.1001/jamapediatrics.2017.1689. PMID: 28715518Free PMC Article
Graham HK, Rosenbaum P, Paneth N, Dan B, Lin JP, Damiano DL, Becher JG, Gaebler-Spira D, Colver A, Reddihough DS, Crompton KE, Lieber RL
Nat Rev Dis Primers 2016 Jan 7;2:15082. doi: 10.1038/nrdp.2015.82. PMID: 27188686Free PMC Article
Wimalasundera N, Stevenson VL
Pract Neurol 2016 Jun;16(3):184-94. Epub 2016 Feb 2 doi: 10.1136/practneurol-2015-001184. PMID: 26837375

Diagnosis

Paul S, Nahar A, Bhagawati M, Kunwar AJ
Oxid Med Cell Longev 2022;2022:2622310. Epub 2022 Jul 30 doi: 10.1155/2022/2622310. PMID: 35941906Free PMC Article
Vitrikas K, Dalton H, Breish D
Am Fam Physician 2020 Feb 15;101(4):213-220. PMID: 32053326
Michael-Asalu A, Taylor G, Campbell H, Lelea LL, Kirby RS
Adv Pediatr 2019 Aug;66:189-208. Epub 2019 May 15 doi: 10.1016/j.yapd.2019.04.002. PMID: 31230694
Novak I, Morgan C, Adde L, Blackman J, Boyd RN, Brunstrom-Hernandez J, Cioni G, Damiano D, Darrah J, Eliasson AC, de Vries LS, Einspieler C, Fahey M, Fehlings D, Ferriero DM, Fetters L, Fiori S, Forssberg H, Gordon AM, Greaves S, Guzzetta A, Hadders-Algra M, Harbourne R, Kakooza-Mwesige A, Karlsson P, Krumlinde-Sundholm L, Latal B, Loughran-Fowlds A, Maitre N, McIntyre S, Noritz G, Pennington L, Romeo DM, Shepherd R, Spittle AJ, Thornton M, Valentine J, Walker K, White R, Badawi N
JAMA Pediatr 2017 Sep 1;171(9):897-907. doi: 10.1001/jamapediatrics.2017.1689. PMID: 28715518Free PMC Article
Wimalasundera N, Stevenson VL
Pract Neurol 2016 Jun;16(3):184-94. Epub 2016 Feb 2 doi: 10.1136/practneurol-2015-001184. PMID: 26837375

Therapy

Rebelo F, Mansur IR, Miglioli TC, Meio MDB, Junior SCG
PLoS One 2022;17(7):e0271993. Epub 2022 Jul 22 doi: 10.1371/journal.pone.0271993. PMID: 35867728Free PMC Article
Liang X, Tan Z, Yun G, Cao J, Wang J, Liu Q, Chen T
J Rehabil Med 2021 Apr 1;53(4):jrm00176. doi: 10.2340/16501977-2772. PMID: 33225375Free PMC Article
Hoare BJ, Wallen MA, Thorley MN, Jackman ML, Carey LM, Imms C
Cochrane Database Syst Rev 2019 Apr 1;4(4):CD004149. doi: 10.1002/14651858.CD004149.pub3. PMID: 30932166Free PMC Article
Novak I, McIntyre S, Morgan C, Campbell L, Dark L, Morton N, Stumbles E, Wilson SA, Goldsmith S
Dev Med Child Neurol 2013 Oct;55(10):885-910. Epub 2013 Aug 21 doi: 10.1111/dmcn.12246. PMID: 23962350
Steultjens EM, Dekker J, Bouter LM, van de Nes JC, Lambregts BL, van den Ende CH
Clin Rehabil 2004 Feb;18(1):1-14. doi: 10.1191/0269215504cr697oa. PMID: 14763715

Prognosis

San Juan AM, Swaroop VT
Pediatr Ann 2022 Sep;51(9):e353-e356. Epub 2022 Sep 1 doi: 10.3928/19382359-20220706-06. PMID: 36098607
Koy A, Timmermann L
Eur J Paediatr Neurol 2017 Jan;21(1):118-121. Epub 2016 May 27 doi: 10.1016/j.ejpn.2016.05.015. PMID: 27289260
Baker R, Esquenazi A, Benedetti MG, Desloovere K
Eur J Phys Rehabil Med 2016 Aug;52(4):560-74. PMID: 27618499
Christy JB, Chapman CG, Murphy P
J Pediatr Rehabil Med 2012;5(3):159-70. doi: 10.3233/PRM-2012-0208. PMID: 23023248
Dabney KW, Lipton GE, Miller F
Curr Opin Pediatr 1997 Feb;9(1):81-8. doi: 10.1097/00008480-199702000-00017. PMID: 9088760

Clinical prediction guides

Novak I, Morgan C, Fahey M, Finch-Edmondson M, Galea C, Hines A, Langdon K, Namara MM, Paton MC, Popat H, Shore B, Khamis A, Stanton E, Finemore OP, Tricks A, Te Velde A, Dark L, Morton N, Badawi N
Curr Neurol Neurosci Rep 2020 Feb 21;20(2):3. doi: 10.1007/s11910-020-1022-z. PMID: 32086598Free PMC Article
Deutz U, Heussen N, Weigt-Usinger K, Leiz S, Raabe C, Polster T, Daniela S, Moll C, Lücke T, Krägeloh-Mann I, Hollmann H, Häusler M
Neuropediatrics 2018 Jun;49(3):185-192. Epub 2018 Feb 27 doi: 10.1055/s-0038-1635121. PMID: 29486504
Wimalasundera N, Stevenson VL
Pract Neurol 2016 Jun;16(3):184-94. Epub 2016 Feb 2 doi: 10.1136/practneurol-2015-001184. PMID: 26837375
Park ES, Rha DW, Shin JS, Kim S, Jung S
Yonsei Med J 2014 Nov;55(6):1736-42. doi: 10.3349/ymj.2014.55.6.1736. PMID: 25323914Free PMC Article
Palisano R, Rosenbaum P, Walter S, Russell D, Wood E, Galuppi B
Dev Med Child Neurol 1997 Apr;39(4):214-23. doi: 10.1111/j.1469-8749.1997.tb07414.x. PMID: 9183258

Recent systematic reviews

McIntyre S, Goldsmith S, Webb A, Ehlinger V, Hollung SJ, McConnell K, Arnaud C, Smithers-Sheedy H, Oskoui M, Khandaker G, Himmelmann K; Global CP Prevalence Group*
Dev Med Child Neurol 2022 Dec;64(12):1494-1506. Epub 2022 Aug 11 doi: 10.1111/dmcn.15346. PMID: 35952356Free PMC Article
Novak I, Morgan C, Fahey M, Finch-Edmondson M, Galea C, Hines A, Langdon K, Namara MM, Paton MC, Popat H, Shore B, Khamis A, Stanton E, Finemore OP, Tricks A, Te Velde A, Dark L, Morton N, Badawi N
Curr Neurol Neurosci Rep 2020 Feb 21;20(2):3. doi: 10.1007/s11910-020-1022-z. PMID: 32086598Free PMC Article
Booth ATC, Buizer AI, Meyns P, Oude Lansink ILB, Steenbrink F, van der Krogt MM
Dev Med Child Neurol 2018 Sep;60(9):866-883. Epub 2018 Mar 7 doi: 10.1111/dmcn.13708. PMID: 29512110
Dewar R, Love S, Johnston LM
Dev Med Child Neurol 2015 Jun;57(6):504-20. Epub 2014 Dec 18 doi: 10.1111/dmcn.12660. PMID: 25523410
Novak I, McIntyre S, Morgan C, Campbell L, Dark L, Morton N, Stumbles E, Wilson SA, Goldsmith S
Dev Med Child Neurol 2013 Oct;55(10):885-910. Epub 2013 Aug 21 doi: 10.1111/dmcn.12246. PMID: 23962350

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