U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Persistent atrial fibrillation

MedGen UID:
749907
Concept ID:
C2585653
Pathologic Function
Synonyms: Atrial Fibrillation, Persistent; Atrial Fibrillations, Persistent; Fibrillation, Persistent Atrial; Fibrillations, Persistent Atrial; Persistent Atrial Fibrillation; Persistent Atrial Fibrillations
SNOMED CT: Persistent atrial fibrillation (440059007)

Professional guidelines

PubMed

Sabouret P, Attias D, Beauvais C, Berthelot E, Bouleti C, Gibault Genty G, Galat A, Hanon O, Hulot JS, Isnard R, Jourdain P, Lamblin N, Lebreton G, Lellouche N, Logeart D, Meune C, Pezel T, Damy T
Ann Cardiol Angeiol (Paris) 2022 Feb;71(1):41-52. Epub 2021 Jul 14 doi: 10.1016/j.ancard.2021.05.004. PMID: 34274113
Gupta D, Ding WY
Heart 2022 Jan;108(2):145-151. Epub 2021 May 14 doi: 10.1136/heartjnl-2020-317422. PMID: 33990408
Margulescu AD, Mont L
Expert Rev Cardiovasc Ther 2017 Aug;15(8):601-618. Epub 2017 Jul 31 doi: 10.1080/14779072.2017.1355237. PMID: 28724315

Recent clinical studies

Etiology

Andrade JG, Deyell MW, Macle L, Wells GA, Bennett M, Essebag V, Champagne J, Roux JF, Yung D, Skanes A, Khaykin Y, Morillo C, Jolly U, Novak P, Lockwood E, Amit G, Angaran P, Sapp J, Wardell S, Lauck S, Cadrin-Tourigny J, Kochhäuser S, Verma A; EARLY-AF Investigators
N Engl J Med 2023 Jan 12;388(2):105-116. Epub 2022 Nov 7 doi: 10.1056/NEJMoa2212540. PMID: 36342178
Yang G, Zheng L, Jiang C, Fan J, Liu X, Zhan X, Li J, Wang L, Yang H, Zhu W, Du H, Ma G, Ma W, Kojodjojo P, Chen M; STABLE-SR-II Investigators
JACC Clin Electrophysiol 2022 Jul;8(7):882-891. Epub 2022 Apr 27 doi: 10.1016/j.jacep.2022.03.012. PMID: 35863814
DeLurgio DB, Crossen KJ, Gill J, Blauth C, Oza SR, Magnano AR, Mostovych MA, Halkos ME, Tschopp DR, Kerendi F, Taigen TL, Shults CC, Shah MH, Rajendra AB, Osorio J, Silver JS, Hook BG, Gilligan DM, Calkins H
Circ Arrhythm Electrophysiol 2020 Dec;13(12):e009288. Epub 2020 Nov 13 doi: 10.1161/CIRCEP.120.009288. PMID: 33185144
Reddy VY, Anic A, Koruth J, Petru J, Funasako M, Minami K, Breskovic T, Sikiric I, Dukkipati SR, Kawamura I, Neuzil P
J Am Coll Cardiol 2020 Sep 1;76(9):1068-1080. doi: 10.1016/j.jacc.2020.07.007. PMID: 32854842
Verma A, Jiang CY, Betts TR, Chen J, Deisenhofer I, Mantovan R, Macle L, Morillo CA, Haverkamp W, Weerasooriya R, Albenque JP, Nardi S, Menardi E, Novak P, Sanders P; STAR AF II Investigators
N Engl J Med 2015 May 7;372(19):1812-22. doi: 10.1056/NEJMoa1408288. PMID: 25946280

Diagnosis

Kuck KH, Lebedev DS, Mikhaylov EN, Romanov A, Gellér L, Kalējs O, Neumann T, Davtyan K, On YK, Popov S, Bongiorni MG, Schlüter M, Willems S, Ouyang F
Europace 2021 Mar 8;23(3):362-369. doi: 10.1093/europace/euaa298. PMID: 33330909Free PMC Article
DeLurgio DB, Crossen KJ, Gill J, Blauth C, Oza SR, Magnano AR, Mostovych MA, Halkos ME, Tschopp DR, Kerendi F, Taigen TL, Shults CC, Shah MH, Rajendra AB, Osorio J, Silver JS, Hook BG, Gilligan DM, Calkins H
Circ Arrhythm Electrophysiol 2020 Dec;13(12):e009288. Epub 2020 Nov 13 doi: 10.1161/CIRCEP.120.009288. PMID: 33185144
Poole JE, Bahnson TD, Monahan KH, Johnson G, Rostami H, Silverstein AP, Al-Khalidi HR, Rosenberg Y, Mark DB, Lee KL, Packer DL; CABANA Investigators and ECG Rhythm Core Lab
J Am Coll Cardiol 2020 Jun 30;75(25):3105-3118. doi: 10.1016/j.jacc.2020.04.065. PMID: 32586583Free PMC Article
Terricabras M, Piccini JP, Verma A
J Cardiovasc Electrophysiol 2020 Jul;31(7):1809-1821. Epub 2019 Dec 18 doi: 10.1111/jce.14311. PMID: 31828883
Margulescu AD, Mont L
Expert Rev Cardiovasc Ther 2017 Aug;15(8):601-618. Epub 2017 Jul 31 doi: 10.1080/14779072.2017.1355237. PMID: 28724315

Therapy

Kistler PM, Chieng D, Sugumar H, Ling LH, Segan L, Azzopardi S, Al-Kaisey A, Parameswaran R, Anderson RD, Hawson J, Prabhu S, Voskoboinik A, Wong G, Morton JB, Pathik B, McLellan AJ, Lee G, Wong M, Finch S, Pathak RK, Raja DC, Sterns L, Ginks M, Reid CM, Sanders P, Kalman JM
JAMA 2023 Jan 10;329(2):127-135. doi: 10.1001/jama.2022.23722. PMID: 36625809Free PMC Article
Andrade JG, Deyell MW, Macle L, Wells GA, Bennett M, Essebag V, Champagne J, Roux JF, Yung D, Skanes A, Khaykin Y, Morillo C, Jolly U, Novak P, Lockwood E, Amit G, Angaran P, Sapp J, Wardell S, Lauck S, Cadrin-Tourigny J, Kochhäuser S, Verma A; EARLY-AF Investigators
N Engl J Med 2023 Jan 12;388(2):105-116. Epub 2022 Nov 7 doi: 10.1056/NEJMoa2212540. PMID: 36342178
Reddy VY, Anic A, Koruth J, Petru J, Funasako M, Minami K, Breskovic T, Sikiric I, Dukkipati SR, Kawamura I, Neuzil P
J Am Coll Cardiol 2020 Sep 1;76(9):1068-1080. doi: 10.1016/j.jacc.2020.07.007. PMID: 32854842
Verma A, Jiang CY, Betts TR, Chen J, Deisenhofer I, Mantovan R, Macle L, Morillo CA, Haverkamp W, Weerasooriya R, Albenque JP, Nardi S, Menardi E, Novak P, Sanders P; STAR AF II Investigators
N Engl J Med 2015 May 7;372(19):1812-22. doi: 10.1056/NEJMoa1408288. PMID: 25946280
Kühlkamp V, Bosch R, Mewis C, Seipel L
Am J Cardiovasc Drugs 2002;2(1):37-42. doi: 10.2165/00129784-200202010-00005. PMID: 14727997

Prognosis

Andrade JG, Deyell MW, Macle L, Wells GA, Bennett M, Essebag V, Champagne J, Roux JF, Yung D, Skanes A, Khaykin Y, Morillo C, Jolly U, Novak P, Lockwood E, Amit G, Angaran P, Sapp J, Wardell S, Lauck S, Cadrin-Tourigny J, Kochhäuser S, Verma A; EARLY-AF Investigators
N Engl J Med 2023 Jan 12;388(2):105-116. Epub 2022 Nov 7 doi: 10.1056/NEJMoa2212540. PMID: 36342178
Derval N, Duchateau J, Denis A, Ramirez FD, Mahida S, André C, Krisai P, Nakatani Y, Kitamura T, Takigawa M, Chauvel R, Tixier R, Pillois X, Sacher F, Hocini M, Haïssaguerre M, Jaïs P, Pambrun T
Heart Rhythm 2021 Apr;18(4):529-537. Epub 2020 Dec 29 doi: 10.1016/j.hrthm.2020.12.023. PMID: 33383226
Reddy VY, Anic A, Koruth J, Petru J, Funasako M, Minami K, Breskovic T, Sikiric I, Dukkipati SR, Kawamura I, Neuzil P
J Am Coll Cardiol 2020 Sep 1;76(9):1068-1080. doi: 10.1016/j.jacc.2020.07.007. PMID: 32854842
Marrouche NF, Brachmann J, Andresen D, Siebels J, Boersma L, Jordaens L, Merkely B, Pokushalov E, Sanders P, Proff J, Schunkert H, Christ H, Vogt J, Bänsch D; CASTLE-AF Investigators
N Engl J Med 2018 Feb 1;378(5):417-427. doi: 10.1056/NEJMoa1707855. PMID: 29385358
Calkins H, Willems S, Gerstenfeld EP, Verma A, Schilling R, Hohnloser SH, Okumura K, Serota H, Nordaby M, Guiver K, Biss B, Brouwer MA, Grimaldi M; RE-CIRCUIT Investigators
N Engl J Med 2017 Apr 27;376(17):1627-1636. Epub 2017 Mar 19 doi: 10.1056/NEJMoa1701005. PMID: 28317415

Clinical prediction guides

Miyama H, Takatsuki S, Ikemura N, Kimura T, Katsumata Y, Yamashita S, Yamaoka K, Ibe S, Seki Y, Yamashita T, Hashimoto K, Ueda I, Ueno K, Ohki T, Fukuda K, Kohsaka S
J Am Heart Assoc 2023 Sep 19;12(18):e029321. Epub 2023 Sep 8 doi: 10.1161/JAHA.122.029321. PMID: 37681532Free PMC Article
Takagi T, Derval N, Duchateau J, Chauvel R, Tixier R, Marchand H, Bouyer B, André C, Kamakura T, Krisai P, Ascione C, Balbo C, Cheniti G, Denis A, Sacher F, Hocini M, Jaïs P, Haïssaguerre M, Pambrun T
Heart Rhythm 2023 Jan;20(1):14-21. Epub 2022 Sep 14 doi: 10.1016/j.hrthm.2022.09.009. PMID: 36115541
Koneru JN
NEJM Evid 2022 Nov;1(11):EVIDe2200246. Epub 2022 Oct 25 doi: 10.1056/EVIDe2200246. PMID: 38319858
Tsiachris D, Giannopoulos G, Deftereos S, Kossyvakis C, Tsioufis C, Siasos G, Oikonomou E, Gatzoulis K, Tousoulis D, Stefanadis C
Curr Med Chem 2019;26(5):925-937. doi: 10.2174/0929867325666180320122930. PMID: 29557741
Mischke K, Knackstedt C, Marx N, Vollmann D
Minerva Med 2013 Apr;104(2):119-30. PMID: 23514988

Recent systematic reviews

Kim JA, Chelu MG
J Interv Card Electrophysiol 2023 Apr;66(3):585-595. Epub 2022 Sep 12 doi: 10.1007/s10840-022-01369-9. PMID: 36089635
Caldonazo T, Kirov H, Rahouma M, Robinson NB, Demetres M, Gaudino M, Doenst T; POAF-MA Group
J Thorac Cardiovasc Surg 2023 Jan;165(1):94-103.e24. Epub 2021 Apr 1 doi: 10.1016/j.jtcvs.2021.03.077. PMID: 33952399
Berger WR, Meulendijks ER, Limpens J, van den Berg NWE, Neefs J, Driessen AHG, Krul SPJ, van Boven WJP, de Groot JR
Int J Cardiol 2019 Mar 1;278:137-143. Epub 2018 Nov 29 doi: 10.1016/j.ijcard.2018.11.127. PMID: 30553497
Anselmino M, Battaglia A, Gallo C, Gili S, Matta M, Castagno D, Ferraris F, Giustetto C, Gaita F
J Cardiovasc Med (Hagerstown) 2015 Dec;16(12):795-801. doi: 10.2459/JCM.0000000000000239. PMID: 25806470
Chen HS, Wen JM, Wu SN, Liu JP
Cochrane Database Syst Rev 2012 Apr 18;(4):CD007101. doi: 10.1002/14651858.CD007101.pub2. PMID: 22513945

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...