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Abnormal neutrophil count

MedGen UID:
663207
•Concept ID:
C0580316
•
Finding
Synonyms: Abnormal neutrophil cell number; Neutrophil count abnormal; Neutrophil count outside reference range
SNOMED CT: Neutrophil count abnormal (165519006); Neutrophil count outside reference range (165519006)
 
HPO: HP:0011991

Definition

A deviation from the normal range of neutrophil cell counts in the circulation. [from HPO]

Conditions with this feature

Specific granule deficiency 1
MedGen UID:
1644049
•Concept ID:
C4551556
•
Disease or Syndrome
Any specific granule deficiency in which the cause of the disease is a mutation in the CEBPE gene.
See: Condition Record
Specific granule deficiency 1

Professional guidelines

PubMed

Tree-based, two-stage risk factor analysis for postoperative sepsis based on Sepsis-3 criteria in elderly patients: A retrospective cohort study.
Peng X, Chen C, Chen J, Wang Y, Yang D, Ma C, Liu Z, Zhou S, Hei Z
Front Public Health 2022;10:1006955. Epub 2022 Sep 26 doi: 10.3389/fpubh.2022.1006955. PMID: 36225784Free PMC Article
Serum albumin level predicts initial intravenous immunoglobulin treatment failure in Kawasaki disease.
Kuo HC, Liang CD, Wang CL, Yu HR, Hwang KP, Yang KD
Acta Paediatr 2010 Oct;99(10):1578-83. Epub 2010 Jun 7 doi: 10.1111/j.1651-2227.2010.01875.x. PMID: 20491705

Recent clinical studies

Etiology

Nomogram for prediction of severe community-acquired pneumonia development in diabetic patients: a multicenter study.
Tan R, Liu B, Zhao C, Yan J, Pan T, Zhou M, Qu H
BMC Pulm Med 2022 Nov 7;22(1):403. doi: 10.1186/s12890-022-02183-9. PMID: 36344933Free PMC Article
Neutrophil counts distinguish between malignancy and arthritis in children with musculoskeletal pain: a case-control study.
Agodi A, Barchitta M, Trigilia C, Barone P, Marino S, Garozzo R, La Rosa M, Russo G, Di Cataldo A
BMC Pediatr 2013 Jan 31;13:15. doi: 10.1186/1471-2431-13-15. PMID: 23368751Free PMC Article
Correlations of inflammatory biomarkers with the onset and prognosis of idiopathic sudden sensorineural hearing loss.
Masuda M, Kanzaki S, Minami S, Kikuchi J, Kanzaki J, Sato H, Ogawa K
Otol Neurotol 2012 Sep;33(7):1142-50. doi: 10.1097/MAO.0b013e3182635417. PMID: 22872174
Multiple markers of inflammation and weight status: cross-sectional analyses throughout childhood.
Skinner AC, Steiner MJ, Henderson FW, Perrin EM
Pediatrics 2010 Apr;125(4):e801-9. Epub 2010 Mar 1 doi: 10.1542/peds.2009-2182. PMID: 20194272Free PMC Article
Prolonged rupture of membranes in the term newborn.
Marlowe SE, Greenwald J, Anwar M, Hiatt M, Hegyi T
Am J Perinatol 1997 Sep;14(8):483-6. doi: 10.1055/s-2007-994185. PMID: 9376011

Diagnosis

Machine learning analyses identify multi-modal frailty factors that selectively discriminate four cohorts in the Alzheimer's disease spectrum: a COMPASS-ND study.
Bohn L, Drouin SM, McFall GP, Rolfson DB, Andrew MK, Dixon RA
BMC Geriatr 2023 Dec 11;23(1):837. doi: 10.1186/s12877-023-04546-1. PMID: 38082372Free PMC Article
Neutrophil counts distinguish between malignancy and arthritis in children with musculoskeletal pain: a case-control study.
Agodi A, Barchitta M, Trigilia C, Barone P, Marino S, Garozzo R, La Rosa M, Russo G, Di Cataldo A
BMC Pediatr 2013 Jan 31;13:15. doi: 10.1186/1471-2431-13-15. PMID: 23368751Free PMC Article
Correlations of inflammatory biomarkers with the onset and prognosis of idiopathic sudden sensorineural hearing loss.
Masuda M, Kanzaki S, Minami S, Kikuchi J, Kanzaki J, Sato H, Ogawa K
Otol Neurotol 2012 Sep;33(7):1142-50. doi: 10.1097/MAO.0b013e3182635417. PMID: 22872174
Multiple markers of inflammation and weight status: cross-sectional analyses throughout childhood.
Skinner AC, Steiner MJ, Henderson FW, Perrin EM
Pediatrics 2010 Apr;125(4):e801-9. Epub 2010 Mar 1 doi: 10.1542/peds.2009-2182. PMID: 20194272Free PMC Article
Prolonged rupture of membranes in the term newborn.
Marlowe SE, Greenwald J, Anwar M, Hiatt M, Hegyi T
Am J Perinatol 1997 Sep;14(8):483-6. doi: 10.1055/s-2007-994185. PMID: 9376011

Therapy

Breastfeeding in infants who aspirate may increase risk of pulmonary inflammation.
Duncan DR, Golden C, Larson K, Williams N, Simoneau T, Rosen RL
Pediatr Pulmonol 2024 Mar;59(3):600-608. Epub 2023 Dec 1 doi: 10.1002/ppul.26788. PMID: 38038162Free PMC Article
Machine learning analyses identify multi-modal frailty factors that selectively discriminate four cohorts in the Alzheimer's disease spectrum: a COMPASS-ND study.
Bohn L, Drouin SM, McFall GP, Rolfson DB, Andrew MK, Dixon RA
BMC Geriatr 2023 Dec 11;23(1):837. doi: 10.1186/s12877-023-04546-1. PMID: 38082372Free PMC Article
Nomogram for prediction of severe community-acquired pneumonia development in diabetic patients: a multicenter study.
Tan R, Liu B, Zhao C, Yan J, Pan T, Zhou M, Qu H
BMC Pulm Med 2022 Nov 7;22(1):403. doi: 10.1186/s12890-022-02183-9. PMID: 36344933Free PMC Article
Acute transient sensorineural hearing loss due to Anaplasma phagocytophilum.
Ghera P, Kasirye Y, Choudhry MW, Shaw GR, Ejercito VS
WMJ 2011 Dec;110(6):288-90. PMID: 22324206

Prognosis

Machine learning analyses identify multi-modal frailty factors that selectively discriminate four cohorts in the Alzheimer's disease spectrum: a COMPASS-ND study.
Bohn L, Drouin SM, McFall GP, Rolfson DB, Andrew MK, Dixon RA
BMC Geriatr 2023 Dec 11;23(1):837. doi: 10.1186/s12877-023-04546-1. PMID: 38082372Free PMC Article
Nomogram for prediction of severe community-acquired pneumonia development in diabetic patients: a multicenter study.
Tan R, Liu B, Zhao C, Yan J, Pan T, Zhou M, Qu H
BMC Pulm Med 2022 Nov 7;22(1):403. doi: 10.1186/s12890-022-02183-9. PMID: 36344933Free PMC Article
Neutrophil counts distinguish between malignancy and arthritis in children with musculoskeletal pain: a case-control study.
Agodi A, Barchitta M, Trigilia C, Barone P, Marino S, Garozzo R, La Rosa M, Russo G, Di Cataldo A
BMC Pediatr 2013 Jan 31;13:15. doi: 10.1186/1471-2431-13-15. PMID: 23368751Free PMC Article
Correlations of inflammatory biomarkers with the onset and prognosis of idiopathic sudden sensorineural hearing loss.
Masuda M, Kanzaki S, Minami S, Kikuchi J, Kanzaki J, Sato H, Ogawa K
Otol Neurotol 2012 Sep;33(7):1142-50. doi: 10.1097/MAO.0b013e3182635417. PMID: 22872174
Prolonged rupture of membranes in the term newborn.
Marlowe SE, Greenwald J, Anwar M, Hiatt M, Hegyi T
Am J Perinatol 1997 Sep;14(8):483-6. doi: 10.1055/s-2007-994185. PMID: 9376011

Clinical prediction guides

Machine learning analyses identify multi-modal frailty factors that selectively discriminate four cohorts in the Alzheimer's disease spectrum: a COMPASS-ND study.
Bohn L, Drouin SM, McFall GP, Rolfson DB, Andrew MK, Dixon RA
BMC Geriatr 2023 Dec 11;23(1):837. doi: 10.1186/s12877-023-04546-1. PMID: 38082372Free PMC Article
Nomogram for prediction of severe community-acquired pneumonia development in diabetic patients: a multicenter study.
Tan R, Liu B, Zhao C, Yan J, Pan T, Zhou M, Qu H
BMC Pulm Med 2022 Nov 7;22(1):403. doi: 10.1186/s12890-022-02183-9. PMID: 36344933Free PMC Article
Neutrophil counts distinguish between malignancy and arthritis in children with musculoskeletal pain: a case-control study.
Agodi A, Barchitta M, Trigilia C, Barone P, Marino S, Garozzo R, La Rosa M, Russo G, Di Cataldo A
BMC Pediatr 2013 Jan 31;13:15. doi: 10.1186/1471-2431-13-15. PMID: 23368751Free PMC Article
The child with a non-blanching rash: how likely is meningococcal disease?
Wells LC, Smith JC, Weston VC, Collier J, Rutter N
Arch Dis Child 2001 Sep;85(3):218-22. doi: 10.1136/adc.85.3.218. PMID: 11517104Free PMC Article
Prolonged rupture of membranes in the term newborn.
Marlowe SE, Greenwald J, Anwar M, Hiatt M, Hegyi T
Am J Perinatol 1997 Sep;14(8):483-6. doi: 10.1055/s-2007-994185. PMID: 9376011

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