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Left ventricular aneurysm

MedGen UID:
636016
•Concept ID:
C0519097
•
Disease or Syndrome
Synonyms: Left Ventricular Aneurysm; Left ventricular wall aneurysmal; LV wall aneurysmal; LVA - Left ventricular aneurysm
SNOMED CT: LV wall aneurysmal (297160003); Left ventricular wall aneurysmal (297160003); LVA - Left ventricular aneurysm (297160003); Left ventricular aneurysm (297160003)
 
HPO: HP:6000144

Definition

A severely scarred portion of infarcted ventricular myocardium that does not contract normally but instead bulges outward while the rest of the ventricle contracts during systole. [from HPO]

Professional guidelines

PubMed

Obstetric anesthesia management of the patient with cardiac disease.
Arendt KW, Lindley KJ
Int J Obstet Anesth 2019 Feb;37:73-85. Epub 2018 Sep 27 doi: 10.1016/j.ijoa.2018.09.011. PMID: 30415799
Treatment outcomes and therapeutic evaluations of patients with left ventricular aneurysm.
Sui Y, Teng S, Qian J, Zhao Z, Zhang Q, Wu Y
J Int Med Res 2019 Jan;47(1):244-251. Epub 2018 Oct 1 doi: 10.1177/0300060518800127. PMID: 30270805Free PMC Article
Congenital left ventricular aneurysms and diverticula: definition, pathophysiology, clinical relevance and treatment.
Ohlow MA
Cardiology 2006;106(2):63-72. Epub 2006 Apr 12 doi: 10.1159/000092634. PMID: 16612072

Recent clinical studies

Etiology

Imaging in Hypertrophic Cardiomyopathy: Beyond Risk Stratification.
Nealy Z, Kramer C
Heart Fail Clin 2023 Oct;19(4):419-428. Epub 2023 Apr 29 doi: 10.1016/j.hfc.2023.03.004. PMID: 37714584Free PMC Article
In Utero Presentation of Left Ventricular Aneurysm.
Ansah DA, Lawrence EJ, Kearney DL, Qureshi AM
Neoreviews 2023 Aug 1;24(8):e530-e537. doi: 10.1542/neo.24-8-e530. PMID: 37525319
Coronary Artery Disease: From Mechanism to Clinical Practice.
Shao C, Wang J, Tian J, Tang YD
Adv Exp Med Biol 2020;1177:1-36. doi: 10.1007/978-981-15-2517-9_1. PMID: 32246442
Left Ventricular Reconstruction for Postinfarction Left Ventricular Aneurysm: Review of Surgical Techniques.
Ruzza A, Czer LSC, Arabia F, Vespignani R, Esmailian F, Cheng W, De Robertis MA, Trento A
Tex Heart Inst J 2017 Oct;44(5):326-335. Epub 2017 Oct 1 doi: 10.14503/THIJ-16-6068. PMID: 29259502Free PMC Article
Surgery for left ventricular aneurysm after myocardial infarction: techniques selection and results assessment.
Chen X, Qiu ZB, Xu M, Liu LL, Jiang YS, Wang LM
Chin Med J (Engl) 2012 Dec;125(24):4373-9. PMID: 23253704

Diagnosis

Imaging in Hypertrophic Cardiomyopathy: Beyond Risk Stratification.
Nealy Z, Kramer C
Heart Fail Clin 2023 Oct;19(4):419-428. Epub 2023 Apr 29 doi: 10.1016/j.hfc.2023.03.004. PMID: 37714584Free PMC Article
Surgery for Ventricular Tachycardia.
Lawrie GM
Methodist Debakey Cardiovasc J 2021 Apr 5;17(1):36-42. Epub 2021 Mar 25 doi: 10.14797/TESU5314. PMID: 34104318Free PMC Article
Coronary Artery Disease: From Mechanism to Clinical Practice.
Shao C, Wang J, Tian J, Tang YD
Adv Exp Med Biol 2020;1177:1-36. doi: 10.1007/978-981-15-2517-9_1. PMID: 32246442
Left Ventricular Reconstruction for Postinfarction Left Ventricular Aneurysm: Review of Surgical Techniques.
Ruzza A, Czer LSC, Arabia F, Vespignani R, Esmailian F, Cheng W, De Robertis MA, Trento A
Tex Heart Inst J 2017 Oct;44(5):326-335. Epub 2017 Oct 1 doi: 10.14503/THIJ-16-6068. PMID: 29259502Free PMC Article
Cardiocutaneous fistula.
Danias PG, Lehman T, Kartis T, Missri JC
Heart 1999 Mar;81(3):325-6. doi: 10.1136/hrt.81.3.325. PMID: 10026366Free PMC Article

Therapy

Giant left ventricular aneurysm following arterial switch operation.
Buczyński M, Karolczak MA, Motylewicz B, Mądry W, Kuśmierczyk M, Szymańska-Beta K, Kopacz P, Zawadzki M, Kuźma J
Kardiol Pol 2022;80(4):501-502. Epub 2022 Mar 8 doi: 10.33963/KP.a2022.0068. PMID: 35258092
Surgery for Ventricular Tachycardia.
Lawrie GM
Methodist Debakey Cardiovasc J 2021 Apr 5;17(1):36-42. Epub 2021 Mar 25 doi: 10.14797/TESU5314. PMID: 34104318Free PMC Article
Results of Left Ventricular Reconstruction With and Without Mitral Valve Surgery.
Song Y, Hu S, Sun H, Song Y, Wang L, Wang W, Pan S, Wang S, Feng W, Zheng Z
Ann Thorac Surg 2020 Mar;109(3):753-761. Epub 2019 Aug 28 doi: 10.1016/j.athoracsur.2019.07.026. PMID: 31472132
Treatment outcomes and therapeutic evaluations of patients with left ventricular aneurysm.
Sui Y, Teng S, Qian J, Zhao Z, Zhang Q, Wu Y
J Int Med Res 2019 Jan;47(1):244-251. Epub 2018 Oct 1 doi: 10.1177/0300060518800127. PMID: 30270805Free PMC Article
Anticoagulation in ischemic left ventricular aneurysm.
Lee GY, Song YB, Hahn JY, Choi SH, Choi JH, Jeon ES, Park SJ, Lee SC, Park SW, Gwon HC
Mayo Clin Proc 2015 Apr;90(4):441-9. Epub 2015 Mar 6 doi: 10.1016/j.mayocp.2014.12.025. PMID: 25752723

Prognosis

Imaging in Hypertrophic Cardiomyopathy: Beyond Risk Stratification.
Nealy Z, Kramer C
Heart Fail Clin 2023 Oct;19(4):419-428. Epub 2023 Apr 29 doi: 10.1016/j.hfc.2023.03.004. PMID: 37714584Free PMC Article
Apical Aneurysms and Mid-Left Ventricular Obstruction in Hypertrophic Cardiomyopathy.
Sherrid MV, Bernard S, Tripathi N, Patel Y, Modi V, Axel L, Talebi S, Ghoshhajra BB, Sanborn DY, Saric M, Adlestein E, Alvarez IC, Xia Y, Swistel DG, Massera D, Fifer MA, Kim B
JACC Cardiovasc Imaging 2023 May;16(5):591-605. Epub 2023 Jan 11 doi: 10.1016/j.jcmg.2022.11.013. PMID: 36681586
Temporal Trends and Outcomes of Left Ventricular Aneurysm After Acute Myocardial Infarction.
Vallabhajosyula S, Kanwar S, Aung H, Cheungpasitporn W, Raphael CE, Gulati R, Singh M
Am J Cardiol 2020 Oct 15;133:32-38. Epub 2020 Jul 28 doi: 10.1016/j.amjcard.2020.07.043. PMID: 32807388
Characteristics and outcome of congenital left ventricular aneurysm and diverticulum: Analysis of 809 cases published since 1816.
Ohlow MA, von Korn H, Lauer B
Int J Cardiol 2015 Apr 15;185:34-45. Epub 2015 Mar 5 doi: 10.1016/j.ijcard.2015.03.050. PMID: 25782048
Lead aVR--the neglected lead.
Chenniappan M, Sankar RU, Saravanan K, Karthikeyan
J Assoc Physicians India 2013 Sep;61(9):650-4. PMID: 24772703

Clinical prediction guides

Apical Aneurysms and Mid-Left Ventricular Obstruction in Hypertrophic Cardiomyopathy.
Sherrid MV, Bernard S, Tripathi N, Patel Y, Modi V, Axel L, Talebi S, Ghoshhajra BB, Sanborn DY, Saric M, Adlestein E, Alvarez IC, Xia Y, Swistel DG, Massera D, Fifer MA, Kim B
JACC Cardiovasc Imaging 2023 May;16(5):591-605. Epub 2023 Jan 11 doi: 10.1016/j.jcmg.2022.11.013. PMID: 36681586
Results of different therapeutic strategies for left ventricular aneurysm with mitral regurgitation.
Ma H, Zhang S, Chen L, Nan Y, Tiemuerniyazi X, Huang S, Zhao D, Feng W
Coron Artery Dis 2022 Sep 1;33(6):440-445. Epub 2022 Apr 5 doi: 10.1097/MCA.0000000000001146. PMID: 35383590
Coronary Artery Disease: From Mechanism to Clinical Practice.
Shao C, Wang J, Tian J, Tang YD
Adv Exp Med Biol 2020;1177:1-36. doi: 10.1007/978-981-15-2517-9_1. PMID: 32246442
Anticoagulation in ischemic left ventricular aneurysm.
Lee GY, Song YB, Hahn JY, Choi SH, Choi JH, Jeon ES, Park SJ, Lee SC, Park SW, Gwon HC
Mayo Clin Proc 2015 Apr;90(4):441-9. Epub 2015 Mar 6 doi: 10.1016/j.mayocp.2014.12.025. PMID: 25752723
Lead aVR--the neglected lead.
Chenniappan M, Sankar RU, Saravanan K, Karthikeyan
J Assoc Physicians India 2013 Sep;61(9):650-4. PMID: 24772703

Recent systematic reviews

Predictors of left ventricular thrombus after acute myocardial infarction: a systematic review and meta-analysis.
Kwok CS, Bennett S, Borovac JA, Schwarz K, Lip GYH
Coron Artery Dis 2023 Jun 1;34(4):250-259. Epub 2023 Mar 13 doi: 10.1097/MCA.0000000000001223. PMID: 36951727
Safety and efficacy of less-invasive ventricular enhancement procedure with the transcatheter Revivent TC(TM) system in patients with left ventricular aneurysm: a systematic review.
Brinza C, Cinteza M, Popa IV, Burlacu A
Rev Cardiovasc Med 2021 Jun 30;22(2):445-452. doi: 10.31083/j.rcm2202050. PMID: 34258911
Congenital left ventricular outpouchings: a systematic review of 839 cases and introduction of a novel classification after two centuries.
Malakan Rad E, Awad S, Hijazi ZM
Congenit Heart Dis 2014 Nov-Dec;9(6):498-511. Epub 2014 Aug 27 doi: 10.1111/chd.12214. PMID: 25159202
Characteristics and outcome of primary congenital left ventricular aneurysm and diverticulum: analysis of cases from the literature.
Ohlow MA, Brunelli M, Lauer B
Prenat Diagn 2014 Sep;34(9):893-9. Epub 2014 May 15 doi: 10.1002/pd.4389. PMID: 24752829

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