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Irritability

MedGen UID:
5898
Concept ID:
C0022107
Finding
Synonyms: Irritable Mood; Irritable Moods; Mood, Irritable; Moods, Irritable
SNOMED CT: Feeling irritable (55929007); Irritability (55929007); Fussiness (55929007)
 

Definition

Abnormal or excessive excitability with easily triggered anger, annoyance, or impatience. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVIrritability

Recent clinical studies

Etiology

Ezpeleta L, Granero R, de la Osa N, Trepat E, Domènech JM
J Abnorm Child Psychol 2016 Jan;44(1):115-28. doi: 10.1007/s10802-015-9972-3. PMID: 25630822
Dougherty LR, Smith VC, Bufferd SJ, Kessel E, Carlson GA, Klein DN
J Child Psychol Psychiatry 2015 Sep;56(9):999-1007. Epub 2015 Feb 27 doi: 10.1111/jcpp.12403. PMID: 26259142Free PMC Article
Mikita N, Hollocks MJ, Papadopoulos AS, Aslani A, Harrison S, Leibenluft E, Simonoff E, Stringaris A
J Child Psychol Psychiatry 2015 Oct;56(10):1118-26. Epub 2015 Jan 28 doi: 10.1111/jcpp.12382. PMID: 25626926Free PMC Article
Fernández de la Cruz L, Simonoff E, McGough JJ, Halperin JM, Arnold LE, Stringaris A
J Am Acad Child Adolesc Psychiatry 2015 Jan;54(1):62-70.e3. Epub 2014 Oct 18 doi: 10.1016/j.jaac.2014.10.006. PMID: 25524791Free PMC Article
Wiggins JL, Mitchell C, Stringaris A, Leibenluft E
J Am Acad Child Adolesc Psychiatry 2014 Nov;53(11):1191-205, 1205.e1-4. Epub 2014 Sep 3 doi: 10.1016/j.jaac.2014.08.005. PMID: 25440309Free PMC Article

Diagnosis

Van Meter A, Youngstrom E, Freeman A, Feeny N, Youngstrom JK, Findling RL
J Child Adolesc Psychopharmacol 2016 Feb;26(1):26-37. Epub 2016 Feb 2 doi: 10.1089/cap.2015.0111. PMID: 26835744Free PMC Article
Ezpeleta L, Granero R, de la Osa N, Trepat E, Domènech JM
J Abnorm Child Psychol 2016 Jan;44(1):115-28. doi: 10.1007/s10802-015-9972-3. PMID: 25630822
Dougherty LR, Smith VC, Bufferd SJ, Kessel E, Carlson GA, Klein DN
J Child Psychol Psychiatry 2015 Sep;56(9):999-1007. Epub 2015 Feb 27 doi: 10.1111/jcpp.12403. PMID: 26259142Free PMC Article
Perlman SB, Jones BM, Wakschlag LS, Axelson D, Birmaher B, Phillips ML
Dev Cogn Neurosci 2015 Aug;14:71-80. Epub 2015 Jul 20 doi: 10.1016/j.dcn.2015.07.003. PMID: 26218424Free PMC Article
Wiggins JL, Mitchell C, Stringaris A, Leibenluft E
J Am Acad Child Adolesc Psychiatry 2014 Nov;53(11):1191-205, 1205.e1-4. Epub 2014 Sep 3 doi: 10.1016/j.jaac.2014.08.005. PMID: 25440309Free PMC Article

Therapy

Sukhodolsky DG, Smith SD, McCauley SA, Ibrahim K, Piasecka JB
J Child Adolesc Psychopharmacol 2016 Feb;26(1):58-64. Epub 2016 Jan 8 doi: 10.1089/cap.2015.0120. PMID: 26745682Free PMC Article
Hammond FM, Sherer M, Malec JF, Zafonte RD, Whitney M, Bell K, Dikmen S, Bogner J, Mysiw J, Pershad R; Amantadine Irritability Multisite Study Group.
J Neurotrauma 2015 Aug 15;32(16):1230-8. Epub 2015 Mar 31 doi: 10.1089/neu.2014.3803. PMID: 25774566Free PMC Article
Fernández de la Cruz L, Simonoff E, McGough JJ, Halperin JM, Arnold LE, Stringaris A
J Am Acad Child Adolesc Psychiatry 2015 Jan;54(1):62-70.e3. Epub 2014 Oct 18 doi: 10.1016/j.jaac.2014.10.006. PMID: 25524791Free PMC Article
Hammond FM, Bickett AK, Norton JH, Pershad R
J Head Trauma Rehabil 2014 Sep-Oct;29(5):391-9. doi: 10.1097/01.HTR.0000438116.56228.de. PMID: 24263176
Blacklaws H, Gardner A, Usher K
J Clin Nurs 2011 May;20(9-10):1215-24. Epub 2011 Mar 3 doi: 10.1111/j.1365-2702.2010.03494.x. PMID: 21371144

Prognosis

Ezpeleta L, Granero R, de la Osa N, Trepat E, Domènech JM
J Abnorm Child Psychol 2016 Jan;44(1):115-28. doi: 10.1007/s10802-015-9972-3. PMID: 25630822
Dougherty LR, Smith VC, Bufferd SJ, Kessel E, Carlson GA, Klein DN
J Child Psychol Psychiatry 2015 Sep;56(9):999-1007. Epub 2015 Feb 27 doi: 10.1111/jcpp.12403. PMID: 26259142Free PMC Article
Copeland WE, Brotman MA, Costello EJ
J Am Acad Child Adolesc Psychiatry 2015 Aug;54(8):635-42. Epub 2015 Jun 2 doi: 10.1016/j.jaac.2015.05.008. PMID: 26210332Free PMC Article
Bouwens JA, van Duijn E, van der Mast RC, Roos RA, Giltay EJ
J Neuropsychiatry Clin Neurosci 2015 Summer;27(3):206-12. Epub 2015 Jun 12 doi: 10.1176/appi.neuropsych.14030051. PMID: 26067436
Savage J, Verhulst B, Copeland W, Althoff RR, Lichtenstein P, Roberson-Nay R
J Am Acad Child Adolesc Psychiatry 2015 May;54(5):377-84. Epub 2015 Feb 28 doi: 10.1016/j.jaac.2015.02.010. PMID: 25901774Free PMC Article

Clinical prediction guides

Van Meter A, Youngstrom E, Freeman A, Feeny N, Youngstrom JK, Findling RL
J Child Adolesc Psychopharmacol 2016 Feb;26(1):26-37. Epub 2016 Feb 2 doi: 10.1089/cap.2015.0111. PMID: 26835744Free PMC Article
Ezpeleta L, Granero R, de la Osa N, Trepat E, Domènech JM
J Abnorm Child Psychol 2016 Jan;44(1):115-28. doi: 10.1007/s10802-015-9972-3. PMID: 25630822
Dougherty LR, Smith VC, Bufferd SJ, Kessel E, Carlson GA, Klein DN
J Child Psychol Psychiatry 2015 Sep;56(9):999-1007. Epub 2015 Feb 27 doi: 10.1111/jcpp.12403. PMID: 26259142Free PMC Article
Copeland WE, Brotman MA, Costello EJ
J Am Acad Child Adolesc Psychiatry 2015 Aug;54(8):635-42. Epub 2015 Jun 2 doi: 10.1016/j.jaac.2015.05.008. PMID: 26210332Free PMC Article
Holtzman S, O'Connor BP, Barata PC, Stewart DE
Assessment 2015 Feb;22(1):101-15. Epub 2014 May 15 doi: 10.1177/1073191114533814. PMID: 24830513Free PMC Article

Recent systematic reviews

Hirsch LE, Pringsheim T
Cochrane Database Syst Rev 2016 Jun 26;(6):CD009043. doi: 10.1002/14651858.CD009043.pub3. PMID: 27344135
Cosci F, Fava GA, Sonino N
Psychother Psychosom 2015;84(1):22-9. Epub 2014 Dec 24 doi: 10.1159/000367913. PMID: 25547421
Swann AC, Suppes T, Ostacher MJ, Eudicone JM, McQuade R, Forbes A, Carlson BX
J Affect Disord 2013 Jan 10;144(1-2):59-64. Epub 2012 Aug 1 doi: 10.1016/j.jad.2012.05.061. PMID: 22858209
Neu M, Corwin E, Lareau SC, Marcheggiani-Howard C
J Spec Pediatr Nurs 2012 Jul;17(3):177-92. Epub 2011 Nov 1 doi: 10.1111/j.1744-6155.2011.00310.x. PMID: 22734872Free PMC Article
Craig KJ, Hietanen H, Markova IS, Berrios GE
Psychiatry Res 2008 Jun 30;159(3):367-75. Epub 2008 Apr 18 doi: 10.1016/j.psychres.2007.03.002. PMID: 18374422

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