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Immune system disorder

MedGen UID:
5759
•Concept ID:
C0021053
•
Disease or Syndrome
Synonym: Immune system disease
SNOMED CT: Immunity disorders (41266007); Disorder of immune system (41266007)
 
Monarch Initiative: MONDO:0005046

Definition

A disorder resulting from an abnormality in the immune system. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVImmune system disorder

Professional guidelines

PubMed

Electrostimulation: A Promising New Treatment for Psoriasis.
Zuo Z, Wang Y, Fang Y, Wang Z, Yang Z, Jia B, Sun Y
Int J Mol Sci 2024 Dec 3;25(23) doi: 10.3390/ijms252313005. PMID: 39684717Free PMC Article
Macrophage activation syndrome in Sepsis: from pathogenesis to clinical management.
Chen S, Zhang C, Luo J, Lin Z, Chang T, Dong L, Chen D, Tang ZH
Inflamm Res 2024 Dec;73(12):2179-2197. Epub 2024 Oct 15 doi: 10.1007/s00011-024-01957-7. PMID: 39404874

Recent clinical studies

Etiology

Assessing the causal relationship between immune cell traits and depression by Mendelian randomization analysis.
Xue H, Chen J, Fan W
J Affect Disord 2024 Jul 1;356:48-53. Epub 2024 Apr 7 doi: 10.1016/j.jad.2024.04.006. PMID: 38593939
Antigen-specific immunotherapies in type 1 diabetes.
Zhang X, Dong Y, Liu D, Yang L, Xu J, Wang Q
J Trace Elem Med Biol 2022 Sep;73:127040. Epub 2022 Jul 15 doi: 10.1016/j.jtemb.2022.127040. PMID: 35868165
Autoimmune diseases in patients undergoing percutaneous coronary intervention: A risk factor for in-stent restenosis?
Pepe M, Napoli G, Carulli E, Moscarelli M, Forleo C, Nestola PL, Biondi-Zoccai G, Giordano A, Favale S
Atherosclerosis 2021 Sep;333:24-31. Epub 2021 Aug 5 doi: 10.1016/j.atherosclerosis.2021.08.007. PMID: 34418682
The incidence and type of cancer in patients with ataxia-telangiectasia via a retrospective single-centre study.
Bakhtiar S, Salzmann-Manrique E, Donath H, Woelke S, Duecker RP, Fritzemeyer S, Schubert R, Huenecke S, Kieslich M, Klingebiel T, Bader P, Zielen S
Br J Haematol 2021 Sep;194(5):879-887. Epub 2021 Aug 1 doi: 10.1111/bjh.17736. PMID: 34337741
Hand preference, immune system disorder and cognitive function among gay/bisexual men: the Multicenter AIDS Cohort Study (MACS).
Becker JT, Bass SM, Dew MA, Kingsley L, Selnes OA, Sheridan K
Neuropsychologia 1992 Mar;30(3):229-35. doi: 10.1016/0028-3932(92)90002-4. PMID: 1574159

Diagnosis

Macrophage activation syndrome in Sepsis: from pathogenesis to clinical management.
Chen S, Zhang C, Luo J, Lin Z, Chang T, Dong L, Chen D, Tang ZH
Inflamm Res 2024 Dec;73(12):2179-2197. Epub 2024 Oct 15 doi: 10.1007/s00011-024-01957-7. PMID: 39404874
Antigen-specific immunotherapies in type 1 diabetes.
Zhang X, Dong Y, Liu D, Yang L, Xu J, Wang Q
J Trace Elem Med Biol 2022 Sep;73:127040. Epub 2022 Jul 15 doi: 10.1016/j.jtemb.2022.127040. PMID: 35868165
An inflammation classification system using cytokine parameters.
Roe K
Scand J Immunol 2021 Feb;93(2):e12970. Epub 2020 Sep 18 doi: 10.1111/sji.12970. PMID: 32892387
Chronic Nonbacterial Osteomyelitis and Chronic Recurrent Multifocal Osteomyelitis in Children.
Zhao Y, Ferguson PJ
Pediatr Clin North Am 2018 Aug;65(4):783-800. doi: 10.1016/j.pcl.2018.04.003. PMID: 30031498
Radiological manifestations of sarcoidosis.
Vagal AS, Shipley R, Meyer CA
Clin Dermatol 2007 May-Jun;25(3):312-25. doi: 10.1016/j.clindermatol.2007.03.009. PMID: 17560309

Therapy

Assessing the causal relationship between immune cell traits and depression by Mendelian randomization analysis.
Xue H, Chen J, Fan W
J Affect Disord 2024 Jul 1;356:48-53. Epub 2024 Apr 7 doi: 10.1016/j.jad.2024.04.006. PMID: 38593939
Autoimmune diseases in patients undergoing percutaneous coronary intervention: A risk factor for in-stent restenosis?
Pepe M, Napoli G, Carulli E, Moscarelli M, Forleo C, Nestola PL, Biondi-Zoccai G, Giordano A, Favale S
Atherosclerosis 2021 Sep;333:24-31. Epub 2021 Aug 5 doi: 10.1016/j.atherosclerosis.2021.08.007. PMID: 34418682
Chronic Nonbacterial Osteomyelitis and Chronic Recurrent Multifocal Osteomyelitis in Children.
Zhao Y, Ferguson PJ
Pediatr Clin North Am 2018 Aug;65(4):783-800. doi: 10.1016/j.pcl.2018.04.003. PMID: 30031498
Advances in mechanisms of systemic lupus erythematosus.
Dema B, Charles N
Discov Med 2014 May;17(95):247-55. PMID: 24882716
Hand preference, immune system disorder and cognitive function among gay/bisexual men: the Multicenter AIDS Cohort Study (MACS).
Becker JT, Bass SM, Dew MA, Kingsley L, Selnes OA, Sheridan K
Neuropsychologia 1992 Mar;30(3):229-35. doi: 10.1016/0028-3932(92)90002-4. PMID: 1574159

Prognosis

Unraveling the complex relationship: Multiple sclerosis, urinary tract infections, and infertility.
Seyedolmohadesin M, Ashkani M, Ghadikolaei TS, Mirshekar M, Bostanghadiri N, Aminzadeh S
Mult Scler Relat Disord 2024 Apr;84:105512. Epub 2024 Feb 20 doi: 10.1016/j.msard.2024.105512. PMID: 38428292
Systemic immune responses after ischemic stroke: From the center to the periphery.
Wu F, Liu Z, Zhou L, Ye D, Zhu Y, Huang K, Weng Y, Xiong X, Zhan R, Shen J
Front Immunol 2022;13:911661. Epub 2022 Sep 20 doi: 10.3389/fimmu.2022.911661. PMID: 36211352Free PMC Article
The incidence and type of cancer in patients with ataxia-telangiectasia via a retrospective single-centre study.
Bakhtiar S, Salzmann-Manrique E, Donath H, Woelke S, Duecker RP, Fritzemeyer S, Schubert R, Huenecke S, Kieslich M, Klingebiel T, Bader P, Zielen S
Br J Haematol 2021 Sep;194(5):879-887. Epub 2021 Aug 1 doi: 10.1111/bjh.17736. PMID: 34337741
Chronic Nonbacterial Osteomyelitis and Chronic Recurrent Multifocal Osteomyelitis in Children.
Zhao Y, Ferguson PJ
Pediatr Clin North Am 2018 Aug;65(4):783-800. doi: 10.1016/j.pcl.2018.04.003. PMID: 30031498
Primary open-angle glaucoma: neuroendocrine-immune disorder?
Zhang T, Xie X, Lu F
Med Hypotheses 2014 Oct;83(4):514-5. Epub 2014 Aug 20 doi: 10.1016/j.mehy.2014.08.017. PMID: 25175405

Clinical prediction guides

Macrophage activation syndrome in Sepsis: from pathogenesis to clinical management.
Chen S, Zhang C, Luo J, Lin Z, Chang T, Dong L, Chen D, Tang ZH
Inflamm Res 2024 Dec;73(12):2179-2197. Epub 2024 Oct 15 doi: 10.1007/s00011-024-01957-7. PMID: 39404874
Assessing the causal relationship between immune cell traits and depression by Mendelian randomization analysis.
Xue H, Chen J, Fan W
J Affect Disord 2024 Jul 1;356:48-53. Epub 2024 Apr 7 doi: 10.1016/j.jad.2024.04.006. PMID: 38593939
Stratified distribution of Th17 and Treg cells in patients with multi-stage rheumatoid arthritis.
Su R, Li B, Wu R, Xie Y, Gao A, Gao C, Li X, Wang C
Arthritis Res Ther 2023 Apr 4;25(1):55. doi: 10.1186/s13075-023-03041-7. PMID: 37016395Free PMC Article
Graves' disease: pathophysiological aspects and considerations about using the chemometric analysis in the study of the disease.
Koseva PM, Kamenov ZA, Nikolova MM, Andreeva-Gateva PA
Folia Med (Plovdiv) 2021 Aug 31;63(4):467-474. doi: 10.3897/folmed.63.e57193. PMID: 35851162
Primary open-angle glaucoma: neuroendocrine-immune disorder?
Zhang T, Xie X, Lu F
Med Hypotheses 2014 Oct;83(4):514-5. Epub 2014 Aug 20 doi: 10.1016/j.mehy.2014.08.017. PMID: 25175405

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