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Abnormal cerebral signs in the newborn

MedGen UID:
542642
•Concept ID:
C0270270
•
Disease or Syndrome
SNOMED CT: Abnormal cerebral signs in the newborn (63814006)

Professional guidelines

PubMed

Neonatal Seizures: Diagnosis, Etiologies, and Management.
Ziobro J, Shellhaas RA
Semin Neurol 2020 Apr;40(2):246-256. Epub 2020 Mar 6 doi: 10.1055/s-0040-1702943. PMID: 32143234
Craniosynostosis - Recognition, clinical characteristics, and treatment.
Kajdic N, Spazzapan P, Velnar T
Bosn J Basic Med Sci 2018 May 20;18(2):110-116. doi: 10.17305/bjbms.2017.2083. PMID: 28623672Free PMC Article
Early, Accurate Diagnosis and Early Intervention in Cerebral Palsy: Advances in Diagnosis and Treatment.
Novak I, Morgan C, Adde L, Blackman J, Boyd RN, Brunstrom-Hernandez J, Cioni G, Damiano D, Darrah J, Eliasson AC, de Vries LS, Einspieler C, Fahey M, Fehlings D, Ferriero DM, Fetters L, Fiori S, Forssberg H, Gordon AM, Greaves S, Guzzetta A, Hadders-Algra M, Harbourne R, Kakooza-Mwesige A, Karlsson P, Krumlinde-Sundholm L, Latal B, Loughran-Fowlds A, Maitre N, McIntyre S, Noritz G, Pennington L, Romeo DM, Shepherd R, Spittle AJ, Thornton M, Valentine J, Walker K, White R, Badawi N
JAMA Pediatr 2017 Sep 1;171(9):897-907. doi: 10.1001/jamapediatrics.2017.1689. PMID: 28715518Free PMC Article

Recent clinical studies

Etiology

Fetal Brain Development in Congenital Heart Disease.
Peyvandi S, Rollins C
Can J Cardiol 2023 Feb;39(2):115-122. Epub 2022 Sep 27 doi: 10.1016/j.cjca.2022.09.020. PMID: 36174913Free PMC Article
A journey through formation and malformations of the neo-cortex.
Reghunath A, Ghasi RG
Childs Nerv Syst 2020 Jan;36(1):27-38. Epub 2019 Nov 27 doi: 10.1007/s00381-019-04429-0. PMID: 31776716
Neu Laxova syndrome.
Dwivedi T, Gosavi M
Indian J Pathol Microbiol 2019 Jan-Mar;62(1):149-152. doi: 10.4103/IJPM.IJPM_351_17. PMID: 30706883
The neonatal brain in critical congenital heart disease: Insights and future directions.
Peyvandi S, Latal B, Miller SP, McQuillen PS
Neuroimage 2019 Jan 15;185:776-782. Epub 2018 May 19 doi: 10.1016/j.neuroimage.2018.05.045. PMID: 29787864
Pediatric neurosonography.
Grant EG, White EM
J Child Neurol 1986 Oct;1(4):319-37. doi: 10.1177/088307388600100403. PMID: 3298401

Diagnosis

Imaging of the Newborn Brain.
Barkovich AJ
Semin Pediatr Neurol 2019 Dec;32:100766. Epub 2019 Sep 6 doi: 10.1016/j.spen.2019.08.002. PMID: 31813522
Craniosynostosis - Recognition, clinical characteristics, and treatment.
Kajdic N, Spazzapan P, Velnar T
Bosn J Basic Med Sci 2018 May 20;18(2):110-116. doi: 10.17305/bjbms.2017.2083. PMID: 28623672Free PMC Article
Acalvaria.
Hawasli AH, Beaumont TL, Vogel TW, Woo AS, Leonard JR
J Neurosurg Pediatr 2014 Aug;14(2):200-2. Epub 2014 Jun 13 doi: 10.3171/2014.5.PEDS13688. PMID: 24926969
Imaging the fetus and the newborn.
Hüppi PS
Top Magn Reson Imaging 2011 Feb;22(1):1. doi: 10.1097/RMR.0b013e3182416f92. PMID: 22186900
Walker-Warburg syndrome.
Vajsar J, Schachter H
Orphanet J Rare Dis 2006 Aug 3;1:29. doi: 10.1186/1750-1172-1-29. PMID: 16887026Free PMC Article

Therapy

Cardiovascular changes during phototherapy in newborns.
Javorka K, Nandrážiová L, Uhríková Z, Czippelová B, Maťašová K, Javorka M, Zibolen M
Physiol Res 2022 Dec 31;71(S2):S179-S186. doi: 10.33549/physiolres.935002. PMID: 36647906Free PMC Article
Congenital Hypothyroidism in Preterm Newborns - The Challenges of Diagnostics and Treatment: A Review.
Klosinska M, Kaczynska A, Ben-Skowronek I
Front Endocrinol (Lausanne) 2022;13:860862. Epub 2022 Mar 18 doi: 10.3389/fendo.2022.860862. PMID: 35370986Free PMC Article
Cerebral Autoregulation in Sick Infants: Current Insights.
Kooi EMW, Richter AE
Clin Perinatol 2020 Sep;47(3):449-467. Epub 2020 May 14 doi: 10.1016/j.clp.2020.05.003. PMID: 32713444
Randomized controlled trial protocol to improve multisensory neural processing, language and motor outcomes in preterm infants.
Neel ML, Yoder P, Matusz PJ, Murray MM, Miller A, Burkhardt S, Emery L, Hague K, Pennington C, Purnell J, Lightfoot M, Maitre NL
BMC Pediatr 2019 Mar 19;19(1):81. doi: 10.1186/s12887-019-1455-1. PMID: 30890132Free PMC Article
The complex aetiology of cerebral palsy.
Korzeniewski SJ, Slaughter J, Lenski M, Haak P, Paneth N
Nat Rev Neurol 2018 Sep;14(9):528-543. doi: 10.1038/s41582-018-0043-6. PMID: 30104744

Prognosis

A journey through formation and malformations of the neo-cortex.
Reghunath A, Ghasi RG
Childs Nerv Syst 2020 Jan;36(1):27-38. Epub 2019 Nov 27 doi: 10.1007/s00381-019-04429-0. PMID: 31776716
Imaging of the Newborn Brain.
Barkovich AJ
Semin Pediatr Neurol 2019 Dec;32:100766. Epub 2019 Sep 6 doi: 10.1016/j.spen.2019.08.002. PMID: 31813522
Neu Laxova syndrome.
Dwivedi T, Gosavi M
Indian J Pathol Microbiol 2019 Jan-Mar;62(1):149-152. doi: 10.4103/IJPM.IJPM_351_17. PMID: 30706883
Brainstem dysgenesis: beyond Moebius syndrome.
Munell F, Tormos MA, Roig-Quilis M
Rev Neurol 2018 Apr 1;66(7):241-250. PMID: 29557550
Walker-Warburg syndrome.
Vajsar J, Schachter H
Orphanet J Rare Dis 2006 Aug 3;1:29. doi: 10.1186/1750-1172-1-29. PMID: 16887026Free PMC Article

Clinical prediction guides

Preterm white matter injury: ultrasound diagnosis and classification.
Agut T, Alarcon A, Cabañas F, Bartocci M, Martinez-Biarge M, Horsch S; eurUS.brain group
Pediatr Res 2020 Mar;87(Suppl 1):37-49. doi: 10.1038/s41390-020-0781-1. PMID: 32218534Free PMC Article
Structural malformations of the brain, eye, and pituitary gland in PHACE syndrome.
Steiner JE, McCoy GN, Hess CP, Dobyns WB, Metry DW, Drolet BA, Maheshwari M, Siegel DH
Am J Med Genet A 2018 Jan;176(1):48-55. Epub 2017 Nov 24 doi: 10.1002/ajmg.a.38523. PMID: 29171184Free PMC Article
Brain Injury and Neurodevelopmental Outcome in Congenital Heart Disease: A Systematic Review.
Mebius MJ, Kooi EMW, Bilardo CM, Bos AF
Pediatrics 2017 Jul;140(1) Epub 2017 Jun 13 doi: 10.1542/peds.2016-4055. PMID: 28607205
Lenticulostriate vasculopathy in neonates: Perspective of the radiologist.
Koral K, Sisman J, Pritchard M, Rosenfeld CR
Early Hum Dev 2015 Jul;91(7):431-5. Epub 2015 May 1 doi: 10.1016/j.earlhumdev.2015.04.003. PMID: 25940000
Prechtl's assessment of general movements: a diagnostic tool for the functional assessment of the young nervous system.
Einspieler C, Prechtl HF
Ment Retard Dev Disabil Res Rev 2005;11(1):61-7. doi: 10.1002/mrdd.20051. PMID: 15856440

Recent systematic reviews

Folic acid supplementation and malaria susceptibility and severity among people taking antifolate antimalarial drugs in endemic areas.
Crider K, Williams J, Qi YP, Gutman J, Yeung L, Mai C, Finkelstain J, Mehta S, Pons-Duran C, Menéndez C, Moraleda C, Rogers L, Daniels K, Green P
Cochrane Database Syst Rev 2022 Feb 1;2(2022) doi: 10.1002/14651858.CD014217. PMID: 36321557Free PMC Article
Perinatal and long-term outcome of fetal intracranial hemorrhage: systematic review and meta-analysis.
Sileo FG, Zöllner J, D'Antonio F, Islam S, Papageorghiou AT, Khalil A
Ultrasound Obstet Gynecol 2022 May;59(5):585-595. doi: 10.1002/uog.24766. PMID: 34529308
Lithium Exposure During Pregnancy and the Postpartum Period: A Systematic Review and Meta-Analysis of Safety and Efficacy Outcomes.
Fornaro M, Maritan E, Ferranti R, Zaninotto L, Miola A, Anastasia A, Murru A, Solé E, Stubbs B, Carvalho AF, Serretti A, Vieta E, Fusar-Poli P, McGuire P, Young AH, Dazzan P, Vigod SN, Correll CU, Solmi M
Am J Psychiatry 2020 Jan 1;177(1):76-92. Epub 2019 Oct 18 doi: 10.1176/appi.ajp.2019.19030228. PMID: 31623458
Early developmental intervention programmes provided post hospital discharge to prevent motor and cognitive impairment in preterm infants.
Spittle A, Orton J, Anderson PJ, Boyd R, Doyle LW
Cochrane Database Syst Rev 2015 Nov 24;2015(11):CD005495. doi: 10.1002/14651858.CD005495.pub4. PMID: 26597166Free PMC Article
Society for maternal-fetal medicine (SMFM) clinical guideline #7: nonimmune hydrops fetalis.
Society for Maternal-Fetal Medicine (SMFM), Norton ME, Chauhan SP, Dashe JS
Am J Obstet Gynecol 2015 Feb;212(2):127-39. Epub 2014 Dec 31 doi: 10.1016/j.ajog.2014.12.018. PMID: 25557883

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