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Rouleaux formation

MedGen UID:
526212
Concept ID:
C0221285
Finding
Synonyms: Increased rouleaux formation; Rouleaux
SNOMED CT: Rouleaux (165496003); Rouleaux formation (39935009)
 
HPO: HP:0031898

Definition

Increased amount of stacking of erythrocytes into long chains. Rouleaux (singular: rouleau) is derived from a French word that can refer to a stack of coins put into a cylindircal paper roll. Rouleaux formation is observed with increased serum proteins, particularly fibrinogen and globulins, and represents the cause of increased erythrocte sedimentation rate because rouleaux sediment more readily than isolated red blood cells. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRouleaux formation

Recent clinical studies

Etiology

Norris SS, Allen DD, Neff TP, Wilkinson SL
Transfusion 1996 Feb;36(2):109-12. doi: 10.1046/j.1537-2995.1996.36296181920.x. PMID: 8614958
Obiefuna PC
J Trop Med Hyg 1991 Feb;94(1):42-4. PMID: 1995933
Sewchand LS, Canham PB
Can J Physiol Pharmacol 1979 Nov;57(11):1213-22. doi: 10.1139/y79-183. PMID: 519523
Goto Y
Jpn J Surg 1974 Dec;4(4):216-21. doi: 10.1007/BF02469455. PMID: 4465473
Salsbury AJ
Br Med J 1967 Oct 14;4(5571):88-90. doi: 10.1136/bmj.4.5571.88. PMID: 6047850Free PMC Article

Diagnosis

Yu P, Zhang J, Tian W, Kang Y
Clin Lab 2020 Jun 1;66(6) doi: 10.7754/Clin.Lab.2019.191127. PMID: 32538055
Ullah H, Akhtar M, Hussain F, Ahmad E, Ahmad M, Aziz MH, Andleeb F, Batool Z
Pak J Pharm Sci 2020 Mar;33(2):589-595. PMID: 32276902
Abramson N
Blood 2006 Jun 1;107(11):4205. PMID: 16739263
Sewchand LS, Canham PB
Can J Physiol Pharmacol 1979 Nov;57(11):1213-22. doi: 10.1139/y79-183. PMID: 519523
Ballas SK
Am J Clin Pathol 1975 Jan;63(1):45-8. doi: 10.1093/ajcp/63.3.45. PMID: 803345

Therapy

Ullah H, Akhtar M, Hussain F, Ahmad E, Ahmad M, Aziz MH, Andleeb F, Batool Z
Pak J Pharm Sci 2020 Mar;33(2):589-595. PMID: 32276902
Lapić I, Miloš M, Tosato F, Piva E, Zadro R, Rogić D, Plebani M
Int J Lab Hematol 2020 Apr;42(2):109-115. Epub 2019 Nov 14 doi: 10.1111/ijlh.13120. PMID: 31725953
Supriyadi R, Darmawan G, Pranggono EH
Acta Med Indones 2019 Oct;51(4):353-355. PMID: 32041921
Forsdyke DR, Ford PM
Biochem J 1983 Jul 15;214(1):257-60. doi: 10.1042/bj2140257. PMID: 6412694Free PMC Article
Sewchand L, Canham PB
Can J Physiol Pharmacol 1976 Aug;54(4):437-42. doi: 10.1139/y76-062. PMID: 974871

Prognosis

Sewastianik T, Guerrera ML, Adler K, Dennis PS, Wright K, Shanmugam V, Huang Y, Tanton H, Jiang M, Kofides A, Demos MG, Dalgarno A, Patel NA, Nag A, Pinkus GS, Yang G, Hunter ZR, Jarolim P, Munshi NC, Treon SP, Carrasco RD
Blood Adv 2019 Nov 12;3(21):3360-3374. doi: 10.1182/bloodadvances.2019000588. PMID: 31698464Free PMC Article
Nevrekar R, Pai A, Khandeparkar A
J Assoc Physicians India 2019 Oct;67(10):20-24. PMID: 31571446
Jonjić N, Seili Bekafigo I, Fučkar Čupić D, Lučin K, Duletić Načinović A, Valković T
Appl Immunohistochem Mol Morphol 2016 Nov/Dec;24(10):e89-e93. doi: 10.1097/PAI.0000000000000361. PMID: 27824644
Greco FA
Pathophysiol Haemost Thromb 2007;36(1):23-31. Epub 2008 Mar 6 doi: 10.1159/000112636. PMID: 18332611
Shiga T, Imaizumi K, Harada N, Sekiya M
Am J Physiol 1983 Aug;245(2):H252-8. doi: 10.1152/ajpheart.1983.245.2.H252. PMID: 6881359

Clinical prediction guides

Szolna-Chodór A, Bosek M, Grzegorzewski B
J Biomed Opt 2015 Feb;20(2):25001. doi: 10.1117/1.JBO.20.2.025001. PMID: 25649625
Barshtein G, Wajnblum D, Yedgar S
Biophys J 2000 May;78(5):2470-4. doi: 10.1016/S0006-3495(00)76791-9. PMID: 10777743Free PMC Article
Norris SS, Allen DD, Neff TP, Wilkinson SL
Transfusion 1996 Feb;36(2):109-12. doi: 10.1046/j.1537-2995.1996.36296181920.x. PMID: 8614958
Shiga T, Imaizumi K, Harada N, Sekiya M
Am J Physiol 1983 Aug;245(2):H252-8. doi: 10.1152/ajpheart.1983.245.2.H252. PMID: 6881359
Goto Y
Jpn J Surg 1974 Dec;4(4):216-21. doi: 10.1007/BF02469455. PMID: 4465473

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