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Mitral valve prolapse

MedGen UID:
504880
Concept ID:
CN001487
Finding
 

Definition

One or both of the leaflets (cusps) of the mitral valve bulges back into the left atrium upon contraction of the left ventricle. [from HPO]

Recent clinical studies

Etiology

Mihos CG, Yucel E, Santana O
J Cardiovasc Surg (Torino) 2017 Oct;58(5):779-786. Epub 2017 Jan 25 doi: 10.23736/S0021-9509.17.09634-3. PMID: 28124513
Xavier J, Haranal MY, Reddy SR, Suryaprakash S
Ann Thorac Surg 2016 Sep;102(3):e217-e219. doi: 10.1016/j.athoracsur.2016.01.098. PMID: 27549547
Perazzolo Marra M, Basso C, De Lazzari M, Rizzo S, Cipriani A, Giorgi B, Lacognata C, Rigato I, Migliore F, Pilichou K, Cacciavillani L, Bertaglia E, Frigo AC, Bauce B, Corrado D, Thiene G, Iliceto S
Circ Cardiovasc Imaging 2016 Aug;9(8):e005030. doi: 10.1161/CIRCIMAGING.116.005030. PMID: 27516479Free PMC Article
Bayer-Topilsky T, Suri RM, Topilsky Y, Marmor YN, Trenerry MR, Antiel RM, Mahoney DW, Schaff HV, Enriquez-Sarano M
Am J Med 2016 Oct;129(10):1100-9. Epub 2016 May 24 doi: 10.1016/j.amjmed.2016.05.004. PMID: 27235006
Nordhues BD, Siontis KC, Scott CG, Nkomo VT, Ackerman MJ, Asirvatham SJ, Noseworthy PA
J Cardiovasc Electrophysiol 2016 Apr;27(4):463-8. Epub 2016 Feb 12 doi: 10.1111/jce.12914. PMID: 26749260

Diagnosis

Xavier J, Haranal MY, Reddy SR, Suryaprakash S
Ann Thorac Surg 2016 Sep;102(3):e217-e219. doi: 10.1016/j.athoracsur.2016.01.098. PMID: 27549547
Boudoulas KD, Pitsis AA, Boudoulas H
Hellenic J Cardiol 2016 Mar-Apr;57(2):73-85. Epub 2016 Apr 6 doi: 10.1016/j.hjc.2016.03.001. PMID: 27445020
Nordhues BD, Siontis KC, Scott CG, Nkomo VT, Ackerman MJ, Asirvatham SJ, Noseworthy PA
J Cardiovasc Electrophysiol 2016 Apr;27(4):463-8. Epub 2016 Feb 12 doi: 10.1111/jce.12914. PMID: 26749260
Narayanan K, Uy-Evanado A, Teodorescu C, Reinier K, Nichols GA, Gunson K, Jui J, Chugh SS
Heart Rhythm 2016 Feb;13(2):498-503. Epub 2015 Sep 28 doi: 10.1016/j.hrthm.2015.09.026. PMID: 26416619Free PMC Article
Kang J, Das B
West J Emerg Med 2015 May;16(3):432-4. Epub 2015 Apr 6 doi: 10.5811/westjem.2015.2.25469. PMID: 25987923Free PMC Article

Therapy

Mihos CG, Yucel E, Santana O
J Cardiovasc Surg (Torino) 2017 Oct;58(5):779-786. Epub 2017 Jan 25 doi: 10.23736/S0021-9509.17.09634-3. PMID: 28124513
Bui AH, Roujol S, Foppa M, Kissinger KV, Goddu B, Hauser TH, Zimetbaum PJ, Ngo LH, Manning WJ, Nezafat R, Delling FN
Heart 2017 Feb;103(3):204-209. Epub 2016 Aug 11 doi: 10.1136/heartjnl-2016-309303. PMID: 27515954Free PMC Article
Perazzolo Marra M, Basso C, De Lazzari M, Rizzo S, Cipriani A, Giorgi B, Lacognata C, Rigato I, Migliore F, Pilichou K, Cacciavillani L, Bertaglia E, Frigo AC, Bauce B, Corrado D, Thiene G, Iliceto S
Circ Cardiovasc Imaging 2016 Aug;9(8):e005030. doi: 10.1161/CIRCIMAGING.116.005030. PMID: 27516479Free PMC Article
Kang J, Das B
West J Emerg Med 2015 May;16(3):432-4. Epub 2015 Apr 6 doi: 10.5811/westjem.2015.2.25469. PMID: 25987923Free PMC Article
Pontone G, Andreini D, Bertella E, Cortinovis S, Mushtaq S, Foti C, Annoni A, Formenti A, Baggiano A, Conte E, Ballerini G, Fiorentini C, Bartorelli AL, Pepi M
Int J Cardiol 2013 Sep 10;167(6):2889-94. Epub 2012 Sep 5 doi: 10.1016/j.ijcard.2012.07.022. PMID: 22959395

Prognosis

Bui AH, Roujol S, Foppa M, Kissinger KV, Goddu B, Hauser TH, Zimetbaum PJ, Ngo LH, Manning WJ, Nezafat R, Delling FN
Heart 2017 Feb;103(3):204-209. Epub 2016 Aug 11 doi: 10.1136/heartjnl-2016-309303. PMID: 27515954Free PMC Article
Xavier J, Haranal MY, Reddy SR, Suryaprakash S
Ann Thorac Surg 2016 Sep;102(3):e217-e219. doi: 10.1016/j.athoracsur.2016.01.098. PMID: 27549547
Perazzolo Marra M, Basso C, De Lazzari M, Rizzo S, Cipriani A, Giorgi B, Lacognata C, Rigato I, Migliore F, Pilichou K, Cacciavillani L, Bertaglia E, Frigo AC, Bauce B, Corrado D, Thiene G, Iliceto S
Circ Cardiovasc Imaging 2016 Aug;9(8):e005030. doi: 10.1161/CIRCIMAGING.116.005030. PMID: 27516479Free PMC Article
Bayer-Topilsky T, Suri RM, Topilsky Y, Marmor YN, Trenerry MR, Antiel RM, Mahoney DW, Schaff HV, Enriquez-Sarano M
Am J Med 2016 Oct;129(10):1100-9. Epub 2016 May 24 doi: 10.1016/j.amjmed.2016.05.004. PMID: 27235006
Nordhues BD, Siontis KC, Scott CG, Nkomo VT, Ackerman MJ, Asirvatham SJ, Noseworthy PA
J Cardiovasc Electrophysiol 2016 Apr;27(4):463-8. Epub 2016 Feb 12 doi: 10.1111/jce.12914. PMID: 26749260

Clinical prediction guides

Mihos CG, Yucel E, Santana O
J Cardiovasc Surg (Torino) 2017 Oct;58(5):779-786. Epub 2017 Jan 25 doi: 10.23736/S0021-9509.17.09634-3. PMID: 28124513
Bui AH, Roujol S, Foppa M, Kissinger KV, Goddu B, Hauser TH, Zimetbaum PJ, Ngo LH, Manning WJ, Nezafat R, Delling FN
Heart 2017 Feb;103(3):204-209. Epub 2016 Aug 11 doi: 10.1136/heartjnl-2016-309303. PMID: 27515954Free PMC Article
Bayer-Topilsky T, Suri RM, Topilsky Y, Marmor YN, Trenerry MR, Antiel RM, Mahoney DW, Schaff HV, Enriquez-Sarano M
Am J Med 2016 Oct;129(10):1100-9. Epub 2016 May 24 doi: 10.1016/j.amjmed.2016.05.004. PMID: 27235006
Narayanan K, Uy-Evanado A, Teodorescu C, Reinier K, Nichols GA, Gunson K, Jui J, Chugh SS
Heart Rhythm 2016 Feb;13(2):498-503. Epub 2015 Sep 28 doi: 10.1016/j.hrthm.2015.09.026. PMID: 26416619Free PMC Article
Pontone G, Andreini D, Bertella E, Cortinovis S, Mushtaq S, Foti C, Annoni A, Formenti A, Baggiano A, Conte E, Ballerini G, Fiorentini C, Bartorelli AL, Pepi M
Int J Cardiol 2013 Sep 10;167(6):2889-94. Epub 2012 Sep 5 doi: 10.1016/j.ijcard.2012.07.022. PMID: 22959395

Recent systematic reviews

Mihos CG, Yucel E, Santana O
J Cardiovasc Surg (Torino) 2017 Oct;58(5):779-786. Epub 2017 Jan 25 doi: 10.23736/S0021-9509.17.09634-3. PMID: 28124513
Tourmousoglou C, Lalos S, Dougenis D
Interact Cardiovasc Thorac Surg 2014 Dec;19(6):1027-35. Epub 2014 Sep 3 doi: 10.1093/icvts/ivu279. PMID: 25185568
Dhoble A, Vedre A, Abdelmoneim SS, Sudini SR, Ghose A, Abela GS, Karve M
Clin Cardiol 2009 Aug;32(8):429-33. doi: 10.1002/clc.20583. PMID: 19685514
Maron BJ, Ackerman MJ, Nishimura RA, Pyeritz RE, Towbin JA, Udelson JE
J Am Coll Cardiol 2005 Apr 19;45(8):1340-5. doi: 10.1016/j.jacc.2005.02.011. PMID: 15837284
Agricola E, Oppizzi M, De Bonis M, Maisano F, Toracca L, Bove T, Alfieri O; American Society of Echocardiography.
J Am Soc Echocardiogr 2003 Jan;16(1):61-6. doi: 10.1067/mje.2003.23. PMID: 12514636

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