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Abnormality of the gastrointestinal tract

MedGen UID:
3828
Concept ID:
C0012242
Disease or Syndrome
Synonyms: Digestive system disease; Gastrointestinal disease
SNOMED CT: Disorder of digestive system (53619000); Gastrointestinal and digestive disorder (53619000); Digestive system disease (53619000)
 

Definition

When you eat, your body breaks food down to a form it can use to build and nourish cells and provide energy. This process is called digestion. . Your digestive system is a series of hollow organs joined in a long, twisting tube. It runs from your mouth to your anus and includes your esophagus, stomach, and small and large intestines. Your liver, gallbladder and pancreas are also involved. They produce juices to help digestion. . There are many types of digestive disorders. The symptoms vary widely depending on the problem. In general, you should see your doctor if you have . -Blood in your stool. -Changes in bowel habits. -Severe abdominal pain. -Unintentional weight loss. -Heartburn not relieved by antacids. NIH: National Institute of Diabetes and Digestive and Kidney Diseases .  [from MedlinePlus]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormality of the gastrointestinal tract

Recent clinical studies

Etiology

Vitetta L, Bambling M, Alford H
Inflammopharmacology 2014 Dec;22(6):333-9. Epub 2014 Sep 30 doi: 10.1007/s10787-014-0216-x. PMID: 25266952
Swanson BJ, Limketkai BN, Liu TC, Montgomery E, Nazari K, Park JY, Santangelo WC, Torbenson MS, Voltaggio L, Yearsley MM, Arnold CA
Am J Surg Pathol 2013 Nov;37(11):1686-93. doi: 10.1097/PAS.0b013e3182999d8d. PMID: 24061514
Valusek PA, St Peter SD, Keckler SJ, Laituri CA, Snyder CL, Ostlie DJ, Holcomb GW 3rd
J Pediatr Surg 2010 Jun;45(6):1169-72. doi: 10.1016/j.jpedsurg.2010.02.083. PMID: 20620314
DeBrosse CW, Case JW, Putnam PE, Collins MH, Rothenberg ME
Pediatr Dev Pathol 2006 May-Jun;9(3):210-8. doi: 10.2350/11-05-0130.1. PMID: 16944979
Ku SK, Lee HS, Lee JH
J Vet Sci 2005 Sep;6(3):191-6. PMID: 16131820

Diagnosis

Vitetta L, Linnane AW, Gobe GC
Toxins (Basel) 2013 Nov 7;5(11):2042-57. doi: 10.3390/toxins5112042. PMID: 24212182Free PMC Article
Swanson BJ, Limketkai BN, Liu TC, Montgomery E, Nazari K, Park JY, Santangelo WC, Torbenson MS, Voltaggio L, Yearsley MM, Arnold CA
Am J Surg Pathol 2013 Nov;37(11):1686-93. doi: 10.1097/PAS.0b013e3182999d8d. PMID: 24061514
Timpone VM, Lattin GE Jr, Lewis RB, Azuar K, Tubay M, Jesinger RA
AJR Am J Roentgenol 2011 Jul;197(1):86-96. doi: 10.2214/AJR.10.7292. PMID: 21701015
Safioleas M, Kaperonis EA, Stamatakos MK, Safioleas C, Manti C, Lygidakis NJ
Hepatogastroenterology 2007 Sep;54(78):1655-7. PMID: 18019687
DeBrosse CW, Case JW, Putnam PE, Collins MH, Rothenberg ME
Pediatr Dev Pathol 2006 May-Jun;9(3):210-8. doi: 10.2350/11-05-0130.1. PMID: 16944979

Therapy

Vitetta L, Bambling M, Alford H
Inflammopharmacology 2014 Dec;22(6):333-9. Epub 2014 Sep 30 doi: 10.1007/s10787-014-0216-x. PMID: 25266952
Vitetta L, Linnane AW, Gobe GC
Toxins (Basel) 2013 Nov 7;5(11):2042-57. doi: 10.3390/toxins5112042. PMID: 24212182Free PMC Article
Swanson BJ, Limketkai BN, Liu TC, Montgomery E, Nazari K, Park JY, Santangelo WC, Torbenson MS, Voltaggio L, Yearsley MM, Arnold CA
Am J Surg Pathol 2013 Nov;37(11):1686-93. doi: 10.1097/PAS.0b013e3182999d8d. PMID: 24061514
Krishnamurthy GT, Krishnamurthy S
Nucl Med Commun 2010 May;31(5):346-54. doi: 10.1097/MNM.0b013e32832fa2c0. PMID: 20147863
Safioleas M, Kaperonis EA, Stamatakos MK, Safioleas C, Manti C, Lygidakis NJ
Hepatogastroenterology 2007 Sep;54(78):1655-7. PMID: 18019687

Prognosis

Kumagai Y, Kawada K, Higashi M, Ishiguro T, Sobajima J, Fukuchi M, Ishibashi K, Baba H, Mochiki E, Aida J, Kawano T, Ishida H, Takubo K
Dis Esophagus 2015 Apr;28(3):269-75. Epub 2014 Jan 28 doi: 10.1111/dote.12183. PMID: 24467464
Swanson BJ, Limketkai BN, Liu TC, Montgomery E, Nazari K, Park JY, Santangelo WC, Torbenson MS, Voltaggio L, Yearsley MM, Arnold CA
Am J Surg Pathol 2013 Nov;37(11):1686-93. doi: 10.1097/PAS.0b013e3182999d8d. PMID: 24061514
Valusek PA, St Peter SD, Keckler SJ, Laituri CA, Snyder CL, Ostlie DJ, Holcomb GW 3rd
J Pediatr Surg 2010 Jun;45(6):1169-72. doi: 10.1016/j.jpedsurg.2010.02.083. PMID: 20620314
Badillo AT, Hedrick HL, Wilson RD, Danzer E, Bebbington MW, Johnson MP, Liechty KW, Flake AW, Adzick NS
J Pediatr Surg 2008 Apr;43(4):647-53. doi: 10.1016/j.jpedsurg.2007.09.016. PMID: 18405710
Weller C, Oxlade N, Dobbs SM, Dobbs RJ, Charlett A, Bjarnason IT
FEMS Immunol Med Microbiol 2005 May 1;44(2):129-35. doi: 10.1016/j.femsim.2005.01.011. PMID: 15866206

Clinical prediction guides

Kumagai Y, Kawada K, Higashi M, Ishiguro T, Sobajima J, Fukuchi M, Ishibashi K, Baba H, Mochiki E, Aida J, Kawano T, Ishida H, Takubo K
Dis Esophagus 2015 Apr;28(3):269-75. Epub 2014 Jan 28 doi: 10.1111/dote.12183. PMID: 24467464
Swanson BJ, Limketkai BN, Liu TC, Montgomery E, Nazari K, Park JY, Santangelo WC, Torbenson MS, Voltaggio L, Yearsley MM, Arnold CA
Am J Surg Pathol 2013 Nov;37(11):1686-93. doi: 10.1097/PAS.0b013e3182999d8d. PMID: 24061514
Chang FY, Chen PH, Wu TC, Pan WH, Chang HY, Wu SJ, Yeh NH, Tang RB, Wu L, James FE
Asia Pac J Clin Nutr 2012;21(4):594-600. PMID: 23017318
DeBrosse CW, Case JW, Putnam PE, Collins MH, Rothenberg ME
Pediatr Dev Pathol 2006 May-Jun;9(3):210-8. doi: 10.2350/11-05-0130.1. PMID: 16944979
Weller C, Oxlade N, Dobbs SM, Dobbs RJ, Charlett A, Bjarnason IT
FEMS Immunol Med Microbiol 2005 May 1;44(2):129-35. doi: 10.1016/j.femsim.2005.01.011. PMID: 15866206

Recent systematic reviews

Zhang X, Zhao M, Du W, Zu D, Sun Y, Xiang R, Yang J
Medicine (Baltimore) 2016 Apr;95(15):e3310. doi: 10.1097/MD.0000000000003310. PMID: 27082573Free PMC Article
Graziano K, Islam S, Dasgupta R, Lopez ME, Austin M, Chen LE, Goldin A, Downard CD, Renaud E, Abdullah F
J Pediatr Surg 2015 Oct;50(10):1783-90. Epub 2015 Jun 30 doi: 10.1016/j.jpedsurg.2015.06.019. PMID: 26205079
Henderson L, Fehily C, Folaranmi S, Kelsey A, McPartland J, Jawaid WB, Craigie R, Losty PD
J Pediatr Surg 2014 Oct;49(10):1513-7. Epub 2014 Jun 25 doi: 10.1016/j.jpedsurg.2014.05.019. PMID: 25280658
Malik AA; Shams-ul-Bari., Wani KA, Khaja AR
Saudi J Gastroenterol 2010 Jan-Mar;16(1):3-7. doi: 10.4103/1319-3767.58760. PMID: 20065566Free PMC Article
Lawson M
Br J Community Nurs 2003 Jul;8(7):296-301. doi: 10.12968/bjcn.2003.8.7.11557. PMID: 12920463

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