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Migraine with or without aura, susceptibility to, 6

MedGen UID:
334829
Concept ID:
C1843765
Finding
Synonym: Migraine with or without aura 6
 
Monarch Initiative: MONDO:0011851
OMIM®: 607516

Clinical features

From HPO
Nausea
MedGen UID:
10196
Concept ID:
C0027497
Sign or Symptom
A sensation of unease in the stomach together with an urge to vomit.
Vomiting
MedGen UID:
12124
Concept ID:
C0042963
Sign or Symptom
Forceful ejection of the contents of the stomach through the mouth by means of a series of involuntary spasmic contractions.
Hemiparesis
MedGen UID:
6783
Concept ID:
C0018989
Finding
Loss of strength in the arm, leg, and sometimes face on one side of the body. Hemiplegia refers to a complete loss of strength, whereas hemiparesis refers to an incomplete loss of strength.
Hemiplegia
MedGen UID:
9196
Concept ID:
C0018991
Sign or Symptom
Paralysis (complete loss of muscle function) in the arm, leg, and in some cases the face on one side of the body.
Photophobia
MedGen UID:
43220
Concept ID:
C0085636
Sign or Symptom
Excessive sensitivity to light with the sensation of discomfort or pain in the eyes due to exposure to bright light.
Migraine with aura
MedGen UID:
57822
Concept ID:
C0154723
Disease or Syndrome
A type of migraine in which there is an aura characterized by focal neurological phenomena that usually proceed, but may accompany or occur in the absence of, the headache. The symptoms of an aura may include fully reversible visual, sensory, and speech symptoms but not motor weakness. Visual symptoms may include flickering lights, spots and lines and/or loss of vision and/or unilateral sensory symptoms such as paresthesias or numbness. At least one of the symptoms of an aura develops gradually over 5 or more minutes and/or different symptoms occur in succession.
Migraine without aura
MedGen UID:
137899
Concept ID:
C0338480
Disease or Syndrome
Repeated headache attacks lasting 4-72 h fulfilling at least two of the following criteria
Phonophobia
MedGen UID:
155864
Concept ID:
C0751466
Mental or Behavioral Dysfunction
An abnormally heightened sensitivity to loud sounds.

Professional guidelines

PubMed

Khan J, Asoom LIA, Sunni AA, Rafique N, Latif R, Saif SA, Almandil NB, Almohazey D, AbdulAzeez S, Borgio JF
Biomed Pharmacother 2021 Jul;139:111557. Epub 2021 May 17 doi: 10.1016/j.biopha.2021.111557. PMID: 34243621
Basura GJ, Adams ME, Monfared A, Schwartz SR, Antonelli PJ, Burkard R, Bush ML, Bykowski J, Colandrea M, Derebery J, Kelly EA, Kerber KA, Koopman CF, Kuch AA, Marcolini E, McKinnon BJ, Ruckenstein MJ, Valenzuela CV, Vosooney A, Walsh SA, Nnacheta LC, Dhepyasuwan N, Buchanan EM
Otolaryngol Head Neck Surg 2020 Apr;162(2_suppl):S1-S55. doi: 10.1177/0194599820909438. PMID: 32267799
Charles A
Lancet Neurol 2018 Feb;17(2):174-182. Epub 2017 Dec 8 doi: 10.1016/S1474-4422(17)30435-0. PMID: 29229375

Recent clinical studies

Etiology

Sun X, Chen B, Qi Y, Wei M, Chen W, Wu X, Wang Q, Li J, Lei X, Luo G
J Headache Pain 2024 Jul 22;25(1):117. doi: 10.1186/s10194-024-01828-w. PMID: 39039470Free PMC Article
Paungarttner J, Quartana M, Patti L, Sklenárová B, Farham F, Jiménez IH, Soylu MG, Vlad IM, Tasdelen S, Mateu T, Marsico O, Reina F, Tischler V, Lampl C; European Headache Federation School of Advanced Studies (EHF – SAS)
J Headache Pain 2024 Jan 26;25(1):11. doi: 10.1186/s10194-024-01719-0. PMID: 38273253Free PMC Article
Grangeon L, Lange KS, Waliszewska-Prosół M, Onan D, Marschollek K, Wiels W, Mikulenka P, Farham F, Gollion C, Ducros A; European Headache Federation School of Advanced Studies (EHF-SAS)
J Headache Pain 2023 Feb 20;24(1):12. doi: 10.1186/s10194-023-01547-8. PMID: 36800925Free PMC Article
Cameron C, Kelly S, Hsieh SC, Murphy M, Chen L, Kotb A, Peterson J, Coyle D, Skidmore B, Gomes T, Clifford T, Wells G
Headache 2015 Jul-Aug;55 Suppl 4:221-35. Epub 2015 Jul 14 doi: 10.1111/head.12601. PMID: 26178694
Schwedt TJ
BMJ 2014 Mar 24;348:g1416. doi: 10.1136/bmj.g1416. PMID: 24662044

Diagnosis

Villar-Martinez MD, Goadsby PJ
Cells 2022 Sep 5;11(17) doi: 10.3390/cells11172767. PMID: 36078174Free PMC Article
Aguilar-Shea AL, Membrilla Md JA, Diaz-de-Teran J
Aten Primaria 2022 Feb;54(2):102208. Epub 2021 Nov 16 doi: 10.1016/j.aprim.2021.102208. PMID: 34798397Free PMC Article
Baloh RW
Semin Neurol 2020 Feb;40(1):76-82. Epub 2020 Jan 14 doi: 10.1055/s-0039-3402735. PMID: 31935766
Ha H, Gonzalez A
Am Fam Physician 2019 Jan 1;99(1):17-24. PMID: 30600979
Silberstein SD
Lancet 2004 Jan 31;363(9406):381-91. doi: 10.1016/S0140-6736(04)15440-8. PMID: 15070571

Therapy

Sun X, Chen B, Qi Y, Wei M, Chen W, Wu X, Wang Q, Li J, Lei X, Luo G
J Headache Pain 2024 Jul 22;25(1):117. doi: 10.1186/s10194-024-01828-w. PMID: 39039470Free PMC Article
Hugger SS, Do TP, Ashina H, Goicochea MT, Jenkins B, Sacco S, Lee MJ, Brennan KC, Amin FM, Steiner TJ, Ashina M
Lancet Neurol 2023 Oct;22(10):934-945. Epub 2023 Sep 14 doi: 10.1016/S1474-4422(23)00206-5. PMID: 37717587
Haghdoost F, Puledda F, Garcia-Azorin D, Huessler EM, Messina R, Pozo-Rosich P
Cephalalgia 2023 Apr;43(4):3331024231159366. doi: 10.1177/03331024231159366. PMID: 36855951
Puledda F, Shields K
Neurotherapeutics 2018 Apr;15(2):336-345. doi: 10.1007/s13311-018-0623-6. PMID: 29616493Free PMC Article
Maasumi K, Tepper SJ, Kriegler JS
Headache 2017 Feb;57(2):194-208. Epub 2016 Dec 2 doi: 10.1111/head.12978. PMID: 27910087

Prognosis

Sun X, Chen B, Qi Y, Wei M, Chen W, Wu X, Wang Q, Li J, Lei X, Luo G
J Headache Pain 2024 Jul 22;25(1):117. doi: 10.1186/s10194-024-01828-w. PMID: 39039470Free PMC Article
Cen J, Wang Q, Cheng L, Gao Q, Wang H, Sun F
J Headache Pain 2024 Jun 7;25(1):96. doi: 10.1186/s10194-024-01798-z. PMID: 38844846Free PMC Article
Chiang CC, Chen SP
Handb Clin Neurol 2024;199:465-474. doi: 10.1016/B978-0-12-823357-3.00021-5. PMID: 38307663
Paungarttner J, Quartana M, Patti L, Sklenárová B, Farham F, Jiménez IH, Soylu MG, Vlad IM, Tasdelen S, Mateu T, Marsico O, Reina F, Tischler V, Lampl C; European Headache Federation School of Advanced Studies (EHF – SAS)
J Headache Pain 2024 Jan 26;25(1):11. doi: 10.1186/s10194-024-01719-0. PMID: 38273253Free PMC Article
Krause DN, Warfvinge K, Haanes KA, Edvinsson L
Nat Rev Neurol 2021 Oct;17(10):621-633. Epub 2021 Sep 20 doi: 10.1038/s41582-021-00544-2. PMID: 34545218

Clinical prediction guides

Sun X, Chen B, Qi Y, Wei M, Chen W, Wu X, Wang Q, Li J, Lei X, Luo G
J Headache Pain 2024 Jul 22;25(1):117. doi: 10.1186/s10194-024-01828-w. PMID: 39039470Free PMC Article
Paungarttner J, Quartana M, Patti L, Sklenárová B, Farham F, Jiménez IH, Soylu MG, Vlad IM, Tasdelen S, Mateu T, Marsico O, Reina F, Tischler V, Lampl C; European Headache Federation School of Advanced Studies (EHF – SAS)
J Headache Pain 2024 Jan 26;25(1):11. doi: 10.1186/s10194-024-01719-0. PMID: 38273253Free PMC Article
Vanood A, Rangel IC, Starling AJ
Neurol Clin 2023 May;41(2):231-247. doi: 10.1016/j.ncl.2023.01.002. PMID: 37030955
Bae JY, Sung HK, Kwon NY, Go HY, Kim TJ, Shin SM, Lee S
Medicina (Kaunas) 2021 Dec 28;58(1) doi: 10.3390/medicina58010044. PMID: 35056352Free PMC Article
von Brevern M, Lempert T
Handb Clin Neurol 2016;137:301-16. doi: 10.1016/B978-0-444-63437-5.00022-4. PMID: 27638080

Recent systematic reviews

Campello CP, Lemos CAA, Andrade WTL, Melo LPF, Nunes GRS, Cavalcanti HG
Int J Audiol 2024 Jan;63(1):1-7. Epub 2022 Dec 2 doi: 10.1080/14992027.2022.2151943. PMID: 36459425
Shaterian N, Shaterian N, Ghanaatpisheh A, Abbasi F, Daniali S, Jahromi MJ, Sanie MS, Abdoli A
Pain Res Manag 2022;2022:3284446. Epub 2022 Mar 31 doi: 10.1155/2022/3284446. PMID: 35401888Free PMC Article
VanderPluym JH, Halker Singh RB, Urtecho M, Morrow AS, Nayfeh T, Torres Roldan VD, Farah MH, Hasan B, Saadi S, Shah S, Abd-Rabu R, Daraz L, Prokop LJ, Murad MH, Wang Z
JAMA 2021 Jun 15;325(23):2357-2369. doi: 10.1001/jama.2021.7939. PMID: 34128998Free PMC Article
Tiseo C, Vacca A, Felbush A, Filimonova T, Gai A, Glazyrina T, Hubalek IA, Marchenko Y, Overeem LH, Piroso S, Tkachev A, Martelletti P, Sacco S; European Headache Federation School of Advanced Studies (EHF-SAS)
J Headache Pain 2020 Oct 27;21(1):126. doi: 10.1186/s10194-020-01192-5. PMID: 33109076Free PMC Article
Hindiyeh NA, Zhang N, Farrar M, Banerjee P, Lombard L, Aurora SK
Headache 2020 Jul;60(7):1300-1316. Epub 2020 May 25 doi: 10.1111/head.13836. PMID: 32449944Free PMC Article

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