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Decreased cardiac output

MedGen UID:
2877
•Concept ID:
C0007166
•
Finding
Synonyms: Cardiac Output, Low; Low Cardiac Output; Output, Low Cardiac
SNOMED CT: Decreased cardiac output (86318000); Alteration in cardiac output: decreased (86318000)
 
HPO: HP:0033532

Definition

A decreased volume of blood pumped by the left and right ventricle, per unit time. Cardiac output (CO) is the product of the heart rate (HR), i.e. the number of heartbeats per minute (bpm), and the stroke volume (SV), which is the volume of blood pumped from the ventricle per beat. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDecreased cardiac output

Professional guidelines

PubMed

Evaluation and Management of Right-Sided Heart Failure: A Scientific Statement From the American Heart Association.
Konstam MA, Kiernan MS, Bernstein D, Bozkurt B, Jacob M, Kapur NK, Kociol RD, Lewis EF, Mehra MR, Pagani FD, Raval AN, Ward C; American Heart Association Council on Clinical Cardiology; Council on Cardiovascular Disease in the Young; and Council on Cardiovascular Surgery and Anesthesia
Circulation 2018 May 15;137(20):e578-e622. Epub 2018 Apr 12 doi: 10.1161/CIR.0000000000000560. PMID: 29650544
Metabolic acidosis: pathophysiology, diagnosis and management.
Kraut JA, Madias NE
Nat Rev Nephrol 2010 May;6(5):274-85. Epub 2010 Mar 23 doi: 10.1038/nrneph.2010.33. PMID: 20308999
Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock.
Dellinger RP, Carlet JM, Masur H, Gerlach H, Calandra T, Cohen J, Gea-Banacloche J, Keh D, Marshall JC, Parker MM, Ramsay G, Zimmerman JL, Vincent JL, Levy MM; Surviving Sepsis Campaign Management Guidelines Committee
Crit Care Med 2004 Mar;32(3):858-73. doi: 10.1097/01.ccm.0000117317.18092.e4. PMID: 15090974

Recent clinical studies

Etiology

Evaluation and Management of Right-Sided Heart Failure: A Scientific Statement From the American Heart Association.
Konstam MA, Kiernan MS, Bernstein D, Bozkurt B, Jacob M, Kapur NK, Kociol RD, Lewis EF, Mehra MR, Pagani FD, Raval AN, Ward C; American Heart Association Council on Clinical Cardiology; Council on Cardiovascular Disease in the Young; and Council on Cardiovascular Surgery and Anesthesia
Circulation 2018 May 15;137(20):e578-e622. Epub 2018 Apr 12 doi: 10.1161/CIR.0000000000000560. PMID: 29650544
Atrial Fibrillation in the ICU.
Bosch NA, Cimini J, Walkey AJ
Chest 2018 Dec;154(6):1424-1434. Epub 2018 Apr 6 doi: 10.1016/j.chest.2018.03.040. PMID: 29627355Free PMC Article
Cirrhotic cardiomyopathy.
Ruiz-del-Árbol L, Serradilla R
World J Gastroenterol 2015 Nov 7;21(41):11502-21. doi: 10.3748/wjg.v21.i41.11502. PMID: 26556983Free PMC Article
Metabolic acidosis: pathophysiology, diagnosis and management.
Kraut JA, Madias NE
Nat Rev Nephrol 2010 May;6(5):274-85. Epub 2010 Mar 23 doi: 10.1038/nrneph.2010.33. PMID: 20308999
Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock.
Dellinger RP, Carlet JM, Masur H, Gerlach H, Calandra T, Cohen J, Gea-Banacloche J, Keh D, Marshall JC, Parker MM, Ramsay G, Zimmerman JL, Vincent JL, Levy MM; Surviving Sepsis Campaign Management Guidelines Committee
Crit Care Med 2004 Mar;32(3):858-73. doi: 10.1097/01.ccm.0000117317.18092.e4. PMID: 15090974

Diagnosis

The physiological basis of pulmonary arterial hypertension.
Naeije R, Richter MJ, Rubin LJ
Eur Respir J 2022 Jun;59(6) Epub 2022 Jun 16 doi: 10.1183/13993003.02334-2021. PMID: 34737219Free PMC Article
Evaluation and Management of Right-Sided Heart Failure: A Scientific Statement From the American Heart Association.
Konstam MA, Kiernan MS, Bernstein D, Bozkurt B, Jacob M, Kapur NK, Kociol RD, Lewis EF, Mehra MR, Pagani FD, Raval AN, Ward C; American Heart Association Council on Clinical Cardiology; Council on Cardiovascular Disease in the Young; and Council on Cardiovascular Surgery and Anesthesia
Circulation 2018 May 15;137(20):e578-e622. Epub 2018 Apr 12 doi: 10.1161/CIR.0000000000000560. PMID: 29650544
Atrial Fibrillation in the ICU.
Bosch NA, Cimini J, Walkey AJ
Chest 2018 Dec;154(6):1424-1434. Epub 2018 Apr 6 doi: 10.1016/j.chest.2018.03.040. PMID: 29627355Free PMC Article
Metabolic acidosis: pathophysiology, diagnosis and management.
Kraut JA, Madias NE
Nat Rev Nephrol 2010 May;6(5):274-85. Epub 2010 Mar 23 doi: 10.1038/nrneph.2010.33. PMID: 20308999
Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock.
Dellinger RP, Carlet JM, Masur H, Gerlach H, Calandra T, Cohen J, Gea-Banacloche J, Keh D, Marshall JC, Parker MM, Ramsay G, Zimmerman JL, Vincent JL, Levy MM; Surviving Sepsis Campaign Management Guidelines Committee
Crit Care Med 2004 Mar;32(3):858-73. doi: 10.1097/01.ccm.0000117317.18092.e4. PMID: 15090974

Therapy

Evaluation and Management of Right-Sided Heart Failure: A Scientific Statement From the American Heart Association.
Konstam MA, Kiernan MS, Bernstein D, Bozkurt B, Jacob M, Kapur NK, Kociol RD, Lewis EF, Mehra MR, Pagani FD, Raval AN, Ward C; American Heart Association Council on Clinical Cardiology; Council on Cardiovascular Disease in the Young; and Council on Cardiovascular Surgery and Anesthesia
Circulation 2018 May 15;137(20):e578-e622. Epub 2018 Apr 12 doi: 10.1161/CIR.0000000000000560. PMID: 29650544
Metabolic acidosis: pathophysiology, diagnosis and management.
Kraut JA, Madias NE
Nat Rev Nephrol 2010 May;6(5):274-85. Epub 2010 Mar 23 doi: 10.1038/nrneph.2010.33. PMID: 20308999
Pediatric considerations.
Parker MM, Hazelzet JA, Carcillo JA
Crit Care Med 2004 Nov;32(11 Suppl):S591-4. doi: 10.1097/01.ccm.0000145904.97821.0d. PMID: 15542968
PEEP and CPAP.
Duncan AW, Oh TE, Hillman DR
Anaesth Intensive Care 1986 Aug;14(3):236-50. doi: 10.1177/0310057X8601400304. PMID: 3530040
Altitude-related illness.
Foulke GE
Am J Emerg Med 1985 May;3(3):217-26. doi: 10.1016/0735-6757(85)90094-4. PMID: 3922385

Prognosis

Syncope: Evaluation and Differential Diagnosis.
Bayard M, Gerayli F, Holt J
Am Fam Physician 2023 Nov;108(5):454-463. PMID: 37983697
Extracorporeal Life Support in Accidental Hypothermia with Cardiac Arrest-A Narrative Review.
Swol J, Darocha T, Paal P, Brugger H, Podsiadło P, Kosiński S, Puślecki M, Ligowski M, Pasquier M
ASAIO J 2022 Feb 1;68(2):153-162. doi: 10.1097/MAT.0000000000001518. PMID: 34261875Free PMC Article
Review of Hypothermia Protocol and Timing of the Echocardiogram.
Pour-Ghaz I, Minhas S, Kayali S, Patel J, Hassan F, Asbeutah AA, Askari R, Ibebuogu UN, Khouzam RN
Curr Probl Cardiol 2021 Apr;46(4):100786. Epub 2021 Jan 7 doi: 10.1016/j.cpcardiol.2021.100786. PMID: 33516091
Genetic determinants of myocardial dysfunction.
Li X, Zhang P
J Med Genet 2017 Jan;54(1):1-10. Epub 2016 Nov 21 doi: 10.1136/jmedgenet-2016-104308. PMID: 27872154
Cirrhotic cardiomyopathy.
Ruiz-del-Árbol L, Serradilla R
World J Gastroenterol 2015 Nov 7;21(41):11502-21. doi: 10.3748/wjg.v21.i41.11502. PMID: 26556983Free PMC Article

Clinical prediction guides

Syncope: Evaluation and Differential Diagnosis.
Bayard M, Gerayli F, Holt J
Am Fam Physician 2023 Nov;108(5):454-463. PMID: 37983697
Pathophysiological, Cellular, and Molecular Events of the Vascular System in Anaphylaxis.
Nuñez-Borque E, Fernandez-Bravo S, Yuste-Montalvo A, Esteban V
Front Immunol 2022;13:836222. Epub 2022 Mar 8 doi: 10.3389/fimmu.2022.836222. PMID: 35371072Free PMC Article
OSA and cardiorespiratory fitness: a review.
Powell TA, Mysliwiec V, Brock MS, Morris MJ
J Clin Sleep Med 2022 Jan 1;18(1):279-288. doi: 10.5664/jcsm.9628. PMID: 34437054Free PMC Article
Congenital heart disease and the liver.
Asrani SK, Asrani NS, Freese DK, Phillips SD, Warnes CA, Heimbach J, Kamath PS
Hepatology 2012 Sep;56(3):1160-9. Epub 2012 Aug 2 doi: 10.1002/hep.25692. PMID: 22383293
Idiopathic hypovolemia.
Fouad FM, Tadena-Thome L, Bravo EL, Tarazi RC
Ann Intern Med 1986 Mar;104(3):298-303. doi: 10.7326/0003-4819-104-3-298. PMID: 3511818

Recent systematic reviews

Stress imaging in patients with a Fontan circulation: A systematic review.
Lanser CNG, van Poecke WHA, Scheffers LE, van den Berg LE, Helbing WA
Int J Cardiol 2023 Nov 15;391:131192. Epub 2023 Jul 19 doi: 10.1016/j.ijcard.2023.131192. PMID: 37479147
Abdominal lift for laparoscopic cholecystectomy.
Gurusamy KS, Koti R, Davidson BR
Cochrane Database Syst Rev 2013 Aug 31;2013(8):CD006574. doi: 10.1002/14651858.CD006574.pub4. PMID: 23996298Free PMC Article
Utility of B-type natriuretic peptides in preeclampsia: a systematic review.
Afshani N, Moustaqim-Barrette A, Biccard BM, Rodseth RN, Dyer RA
Int J Obstet Anesth 2013 Apr;22(2):96-103. Epub 2013 Feb 23 doi: 10.1016/j.ijoa.2012.11.001. PMID: 23462297
Abdominal lift for laparoscopic cholecystectomy.
Gurusamy KS, Koti R, Samraj K, Davidson BR
Cochrane Database Syst Rev 2012 May 16;(5):CD006574. doi: 10.1002/14651858.CD006574.pub3. PMID: 22592713
Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock.
Dellinger RP, Carlet JM, Masur H, Gerlach H, Calandra T, Cohen J, Gea-Banacloche J, Keh D, Marshall JC, Parker MM, Ramsay G, Zimmerman JL, Vincent JL, Levy MM; Surviving Sepsis Campaign Management Guidelines Committee
Crit Care Med 2004 Mar;32(3):858-73. doi: 10.1097/01.ccm.0000117317.18092.e4. PMID: 15090974

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