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Childhood leukemia

MedGen UID:
234132
•Concept ID:
C1332977
•
Neoplastic Process
Synonyms: childhood leukaemia (disease); Childhood Leukemia; childhood leukemia; childhood leukemia (disease); leukaemia (disease) of childhood; leukemia (disease) of childhood; paediatric leukaemia (disease); pediatric leukemia (disease)
 
Monarch Initiative: MONDO:0004355

Definition

An acute or chronic leukemia that occurs during childhood. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVChildhood leukemia

Professional guidelines

PubMed

Delivery of PEGylated liposomal doxorubicin by bispecific antibodies improves treatment in models of high-risk childhood leukemia.
Moles E, Howard CB, Huda P, Karsa M, McCalmont H, Kimpton K, Duly A, Chen Y, Huang Y, Tursky ML, Ma D, Bustamante S, Pickford R, Connerty P, Omari S, Jolly CJ, Joshi S, Shen S, Pimanda JE, Dolnikov A, Cheung LC, Kotecha RS, Norris MD, Haber M, de Bock CE, Somers K, Lock RB, Thurecht KJ, Kavallaris M
Sci Transl Med 2023 May 17;15(696):eabm1262. doi: 10.1126/scitranslmed.abm1262. PMID: 37196067
Cardiotoxicity: A Major Setback in Childhood Leukemia Treatment.
Lazăr DR, Farcaş AD, Blag C, Neaga A, Zdrenghea MT, Căinap C, Lazăr FL, Stef A, Căinap SS
Dis Markers 2021;2021:8828410. Epub 2021 Jan 6 doi: 10.1155/2021/8828410. PMID: 33505537Free PMC Article
Foreword: Childhood Leukemia and Primary Prevention.
Etzel RA
Curr Probl Pediatr Adolesc Health Care 2016 Oct;46(10):315-316. doi: 10.1016/j.cppeds.2016.08.003. PMID: 27968953

Recent clinical studies

Etiology

Childhood B-Cell Preleukemia Mouse Modeling.
Isidro-Hernández M, Alemán-Arteaga S, Casado-García A, Ruiz-Corzo B, Riesco S, Prieto-Matos P, Martínez-Cano J, Sánchez L, Cobaleda C, Sánchez-García I, Vicente-Dueñas C
Int J Mol Sci 2022 Jul 8;23(14) doi: 10.3390/ijms23147562. PMID: 35886910Free PMC Article
Risk Factors for Childhood Leukemia: Radiation and Beyond.
Schmidt JA, Hornhardt S, Erdmann F, Sánchez-García I, Fischer U, Schüz J, Ziegelberger G
Front Public Health 2021;9:805757. Epub 2021 Dec 24 doi: 10.3389/fpubh.2021.805757. PMID: 35004601Free PMC Article
Exposure to pesticides and childhood leukemia risk: A systematic review and meta-analysis.
Karalexi MA, Tagkas CF, Markozannes G, Tseretopoulou X, Hernández AF, Schüz J, Halldorsson TI, Psaltopoulou T, Petridou ET, Tzoulaki I, Ntzani EE
Environ Pollut 2021 Sep 15;285:117376. Epub 2021 May 18 doi: 10.1016/j.envpol.2021.117376. PMID: 34380208
Residential mobility and childhood leukemia.
Amoon AT, Oksuzyan S, Crespi CM, Arah OA, Cockburn M, Vergara X, Kheifets L
Environ Res 2018 Jul;164:459-466. Epub 2018 Mar 23 doi: 10.1016/j.envres.2018.03.016. PMID: 29574256Free PMC Article
The childhood leukemias.
Colby-Graham MF, Chordas C
J Pediatr Nurs 2003 Apr;18(2):87-95. doi: 10.1053/jpdn.2003.9. PMID: 12720205

Diagnosis

What Is Childhood Leukemia?
Ruiz J, Mathews C, Friehling E
JAMA 2024 Mar 5;331(9):808. doi: 10.1001/jama.2023.24648. PMID: 38334982
Genes and childhood leukemia.
Kęsy J, Januszkiewicz-Lewandowska D
Postepy Hig Med Dosw (Online) 2015 Mar 5;69:302-8. doi: 10.5604/17322693.1142719. PMID: 25748621
The diagnosis and classification of osteonecrosis in patients with childhood leukemia.
Niinimäki T, Harila-Saari A, Niinimäki R
Pediatr Blood Cancer 2015 Feb;62(2):198-203. Epub 2014 Oct 30 doi: 10.1002/pbc.25295. PMID: 25359608
Leukemia and lymphoma.
Guillerman RP, Voss SD, Parker BR
Radiol Clin North Am 2011 Jul;49(4):767-97, vii. Epub 2011 Jun 25 doi: 10.1016/j.rcl.2011.05.004. PMID: 21807173
The childhood leukemias.
Colby-Graham MF, Chordas C
J Pediatr Nurs 2003 Apr;18(2):87-95. doi: 10.1053/jpdn.2003.9. PMID: 12720205

Therapy

Exposure to pesticides and childhood leukemia risk: A systematic review and meta-analysis.
Karalexi MA, Tagkas CF, Markozannes G, Tseretopoulou X, Hernández AF, Schüz J, Halldorsson TI, Psaltopoulou T, Petridou ET, Tzoulaki I, Ntzani EE
Environ Pollut 2021 Sep 15;285:117376. Epub 2021 May 18 doi: 10.1016/j.envpol.2021.117376. PMID: 34380208
Residential mobility and childhood leukemia.
Amoon AT, Oksuzyan S, Crespi CM, Arah OA, Cockburn M, Vergara X, Kheifets L
Environ Res 2018 Jul;164:459-466. Epub 2018 Mar 23 doi: 10.1016/j.envres.2018.03.016. PMID: 29574256Free PMC Article
Environmental Exposure and Risk of Childhood Leukemia: An Overview.
Schüz J, Erdmann F
Arch Med Res 2016 Nov;47(8):607-614. doi: 10.1016/j.arcmed.2016.11.017. PMID: 28476188
A history of cancer chemotherapy.
DeVita VT Jr, Chu E
Cancer Res 2008 Nov 1;68(21):8643-53. doi: 10.1158/0008-5472.CAN-07-6611. PMID: 18974103
The childhood leukemias.
Colby-Graham MF, Chordas C
J Pediatr Nurs 2003 Apr;18(2):87-95. doi: 10.1053/jpdn.2003.9. PMID: 12720205

Prognosis

Residential mobility and childhood leukemia.
Amoon AT, Oksuzyan S, Crespi CM, Arah OA, Cockburn M, Vergara X, Kheifets L
Environ Res 2018 Jul;164:459-466. Epub 2018 Mar 23 doi: 10.1016/j.envres.2018.03.016. PMID: 29574256Free PMC Article
Environmental Exposure and Risk of Childhood Leukemia: An Overview.
Schüz J, Erdmann F
Arch Med Res 2016 Nov;47(8):607-614. doi: 10.1016/j.arcmed.2016.11.017. PMID: 28476188
Genes and childhood leukemia.
Kęsy J, Januszkiewicz-Lewandowska D
Postepy Hig Med Dosw (Online) 2015 Mar 5;69:302-8. doi: 10.5604/17322693.1142719. PMID: 25748621
Breastfeeding and maternal and infant health outcomes in developed countries.
Ip S, Chung M, Raman G, Chew P, Magula N, DeVine D, Trikalinos T, Lau J
Evid Rep Technol Assess (Full Rep) 2007 Apr;(153):1-186. PMID: 17764214Free PMC Article
The childhood leukemias.
Colby-Graham MF, Chordas C
J Pediatr Nurs 2003 Apr;18(2):87-95. doi: 10.1053/jpdn.2003.9. PMID: 12720205

Clinical prediction guides

Electromagnetic Radiation Exposure and Childhood Leukemia: Meta-Analysis and Systematic Review.
Guo H, Kang L, Qin W, Li Y
Altern Ther Health Med 2023 Nov;29(8):75-81. PMID: 37678874
Evaluation of Maternal Infection During Pregnancy and Childhood Leukemia Among Offspring in Denmark.
He JR, Yu Y, Fang F, Gissler M, Magnus P, László KD, Ward MH, Paltiel O, Tikellis G, Maule MM, Qiu X, Du J, Valdimarsdóttir UA, Rahimi K, Wiemels JL, Linet MS, Hirst JE, Li J, Dwyer T
JAMA Netw Open 2023 Feb 1;6(2):e230133. doi: 10.1001/jamanetworkopen.2023.0133. PMID: 36808241Free PMC Article
Exposure to pesticides and childhood leukemia risk: A systematic review and meta-analysis.
Karalexi MA, Tagkas CF, Markozannes G, Tseretopoulou X, Hernández AF, Schüz J, Halldorsson TI, Psaltopoulou T, Petridou ET, Tzoulaki I, Ntzani EE
Environ Pollut 2021 Sep 15;285:117376. Epub 2021 May 18 doi: 10.1016/j.envpol.2021.117376. PMID: 34380208
Residential mobility and childhood leukemia.
Amoon AT, Oksuzyan S, Crespi CM, Arah OA, Cockburn M, Vergara X, Kheifets L
Environ Res 2018 Jul;164:459-466. Epub 2018 Mar 23 doi: 10.1016/j.envres.2018.03.016. PMID: 29574256Free PMC Article
Infectious Agents in Childhood Leukemia.
Arellano-Galindo J, Barrera AP, Jiménez-Hernández E, Zavala-Vega S, Campos-Valdéz G, Xicohtencatl-Cortes J, Ochoa SA, Cruz-Córdova A, Crisóstomo-Vázquez MDP, Fernández-Macías JC, Mejía-Aranguré JM
Arch Med Res 2017 May;48(4):305-313. doi: 10.1016/j.arcmed.2017.09.001. PMID: 29157671

Recent systematic reviews

Electromagnetic Radiation Exposure and Childhood Leukemia: Meta-Analysis and Systematic Review.
Guo H, Kang L, Qin W, Li Y
Altern Ther Health Med 2023 Nov;29(8):75-81. PMID: 37678874
Exposure to pesticides and childhood leukemia risk: A systematic review and meta-analysis.
Karalexi MA, Tagkas CF, Markozannes G, Tseretopoulou X, Hernández AF, Schüz J, Halldorsson TI, Psaltopoulou T, Petridou ET, Tzoulaki I, Ntzani EE
Environ Pollut 2021 Sep 15;285:117376. Epub 2021 May 18 doi: 10.1016/j.envpol.2021.117376. PMID: 34380208
Breastfeeding and Childhood Leukemia Incidence: A Meta-analysis and Systematic Review.
Amitay EL, Keinan-Boker L
JAMA Pediatr 2015 Jun;169(6):e151025. Epub 2015 Jun 1 doi: 10.1001/jamapediatrics.2015.1025. PMID: 26030516
Residential traffic exposure and childhood leukemia: a systematic review and meta-analysis.
Boothe VL, Boehmer TK, Wendel AM, Yip FY
Am J Prev Med 2014 Apr;46(4):413-22. doi: 10.1016/j.amepre.2013.11.004. PMID: 24650845Free PMC Article
Residential pesticides and childhood leukemia: a systematic review and meta-analysis.
Turner MC, Wigle DT, Krewski D
Cien Saude Colet 2011 Mar;16(3):1915-31. doi: 10.1590/s1413-81232011000300026. PMID: 21519680

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