U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Parkinsonian syndrome due to neurodegenerative disease

MedGen UID:
1842750
•Concept ID:
C5681086
•
Disease or Syndrome
Synonym: Rare parkinsonian syndrome due to neurodegenerative disease
 
Orphanet: ORPHA306666

Professional guidelines

PubMed

Physical Therapist Management of Parkinson Disease: A Clinical Practice Guideline From the American Physical Therapy Association.
Osborne JA, Botkin R, Colon-Semenza C, DeAngelis TR, Gallardo OG, Kosakowski H, Martello J, Pradhan S, Rafferty M, Readinger JL, Whitt AL, Ellis TD
Phys Ther 2022 Apr 1;102(4) doi: 10.1093/ptj/pzab302. PMID: 34963139Free PMC Article
Diagnosis and Treatment of Parkinson Disease: A Review.
Armstrong MJ, Okun MS
JAMA 2020 Feb 11;323(6):548-560. doi: 10.1001/jama.2019.22360. PMID: 32044947
MDS clinical diagnostic criteria for Parkinson's disease.
Postuma RB, Berg D, Stern M, Poewe W, Olanow CW, Oertel W, Obeso J, Marek K, Litvan I, Lang AE, Halliday G, Goetz CG, Gasser T, Dubois B, Chan P, Bloem BR, Adler CH, Deuschl G
Mov Disord 2015 Oct;30(12):1591-601. doi: 10.1002/mds.26424. PMID: 26474316

Recent clinical studies

Etiology

Life style and Parkinson's disease.
Reichmann H, Csoti I, Koschel J, Lorenzl S, Schrader C, Winkler J, Wüllner U
J Neural Transm (Vienna) 2022 Sep;129(9):1235-1245. Epub 2022 May 23 doi: 10.1007/s00702-022-02509-1. PMID: 35606622Free PMC Article
Inflammation and immune dysfunction in Parkinson disease.
Tansey MG, Wallings RL, Houser MC, Herrick MK, Keating CE, Joers V
Nat Rev Immunol 2022 Nov;22(11):657-673. Epub 2022 Mar 4 doi: 10.1038/s41577-022-00684-6. PMID: 35246670Free PMC Article
Challenges in the diagnosis of Parkinson's disease.
Tolosa E, Garrido A, Scholz SW, Poewe W
Lancet Neurol 2021 May;20(5):385-397. doi: 10.1016/S1474-4422(21)00030-2. PMID: 33894193Free PMC Article
Parkinson's Disease and Parkinsonism.
Hayes MT
Am J Med 2019 Jul;132(7):802-807. Epub 2019 Mar 16 doi: 10.1016/j.amjmed.2019.03.001. PMID: 30890425
Parkinson's disease: clinical features and diagnosis.
Jankovic J
J Neurol Neurosurg Psychiatry 2008 Apr;79(4):368-76. doi: 10.1136/jnnp.2007.131045. PMID: 18344392

Diagnosis

Multiple system atrophy.
Poewe W, Stankovic I, Halliday G, Meissner WG, Wenning GK, Pellecchia MT, Seppi K, Palma JA, Kaufmann H
Nat Rev Dis Primers 2022 Aug 25;8(1):56. doi: 10.1038/s41572-022-00382-6. PMID: 36008429
A Practical Approach to Early-Onset Parkinsonism.
Riboldi GM, Frattini E, Monfrini E, Frucht SJ, Di Fonzo A
J Parkinsons Dis 2022;12(1):1-26. doi: 10.3233/JPD-212815. PMID: 34569973Free PMC Article
MRI Signs of Parkinson's Disease and Atypical Parkinsonism.
Aludin S, Schmill LA
Rofo 2021 Dec;193(12):1403-1410. Epub 2021 May 25 doi: 10.1055/a-1460-8795. PMID: 34034347
New evidence on the management of Lewy body dementia.
Taylor JP, McKeith IG, Burn DJ, Boeve BF, Weintraub D, Bamford C, Allan LM, Thomas AJ, O'Brien JT
Lancet Neurol 2020 Feb;19(2):157-169. Epub 2019 Sep 10 doi: 10.1016/S1474-4422(19)30153-X. PMID: 31519472Free PMC Article
Parkinson's Disease and Parkinsonism.
Hayes MT
Am J Med 2019 Jul;132(7):802-807. Epub 2019 Mar 16 doi: 10.1016/j.amjmed.2019.03.001. PMID: 30890425

Therapy

Role of neuroinflammation in neurodegeneration development.
Zhang W, Xiao D, Mao Q, Xia H
Signal Transduct Target Ther 2023 Jul 12;8(1):267. doi: 10.1038/s41392-023-01486-5. PMID: 37433768Free PMC Article
Glucagon-like peptide-1 (GLP-1) receptor agonists and neuroinflammation: Implications for neurodegenerative disease treatment.
Kopp KO, Glotfelty EJ, Li Y, Greig NH
Pharmacol Res 2022 Dec;186:106550. Epub 2022 Nov 11 doi: 10.1016/j.phrs.2022.106550. PMID: 36372278Free PMC Article
Autonomic dysfunction in Parkinson's disease: Implications for pathophysiology, diagnosis, and treatment.
Chen Z, Li G, Liu J
Neurobiol Dis 2020 Feb;134:104700. Epub 2019 Dec 3 doi: 10.1016/j.nbd.2019.104700. PMID: 31809788
Parkinson's Disease and Parkinsonism.
Hayes MT
Am J Med 2019 Jul;132(7):802-807. Epub 2019 Mar 16 doi: 10.1016/j.amjmed.2019.03.001. PMID: 30890425
Parkinson Disease.
Capriotti T, Terzakis K
Home Healthc Now 2016 Jun;34(6):300-7. doi: 10.1097/NHH.0000000000000398. PMID: 27243427

Prognosis

The epidemiology of Parkinson's disease.
Ben-Shlomo Y, Darweesh S, Llibre-Guerra J, Marras C, San Luciano M, Tanner C
Lancet 2024 Jan 20;403(10423):283-292. doi: 10.1016/S0140-6736(23)01419-8. PMID: 38245248Free PMC Article
Multiple system atrophy.
Poewe W, Stankovic I, Halliday G, Meissner WG, Wenning GK, Pellecchia MT, Seppi K, Palma JA, Kaufmann H
Nat Rev Dis Primers 2022 Aug 25;8(1):56. doi: 10.1038/s41572-022-00382-6. PMID: 36008429
Life style and Parkinson's disease.
Reichmann H, Csoti I, Koschel J, Lorenzl S, Schrader C, Winkler J, Wüllner U
J Neural Transm (Vienna) 2022 Sep;129(9):1235-1245. Epub 2022 May 23 doi: 10.1007/s00702-022-02509-1. PMID: 35606622Free PMC Article
Challenges in the diagnosis of Parkinson's disease.
Tolosa E, Garrido A, Scholz SW, Poewe W
Lancet Neurol 2021 May;20(5):385-397. doi: 10.1016/S1474-4422(21)00030-2. PMID: 33894193Free PMC Article
The Emerging Evidence of the Parkinson Pandemic.
Dorsey ER, Sherer T, Okun MS, Bloem BR
J Parkinsons Dis 2018;8(s1):S3-S8. doi: 10.3233/JPD-181474. PMID: 30584159Free PMC Article

Clinical prediction guides

Lipids as Emerging Biomarkers in Neurodegenerative Diseases.
Wei J, Wong LC, Boland S
Int J Mol Sci 2023 Dec 21;25(1) doi: 10.3390/ijms25010131. PMID: 38203300Free PMC Article
Amyloid β, Tau, and α-Synuclein aggregates in the pathogenesis, prognosis, and therapeutics for neurodegenerative diseases.
Sengupta U, Kayed R
Prog Neurobiol 2022 Jul;214:102270. Epub 2022 Apr 18 doi: 10.1016/j.pneurobio.2022.102270. PMID: 35447272
Autonomic dysfunction in Parkinson's disease: Implications for pathophysiology, diagnosis, and treatment.
Chen Z, Li G, Liu J
Neurobiol Dis 2020 Feb;134:104700. Epub 2019 Dec 3 doi: 10.1016/j.nbd.2019.104700. PMID: 31809788
Parkinson Matters.
Darweesh SKL, Raphael KG, Brundin P, Matthews H, Wyse RK, Chen H, Bloem BR
J Parkinsons Dis 2018;8(4):495-498. doi: 10.3233/JPD-181374. PMID: 30149463Free PMC Article
Olfactory Dysfunction in Neurodegenerative Diseases.
Marin C, Vilas D, Langdon C, Alobid I, López-Chacón M, Haehner A, Hummel T, Mullol J
Curr Allergy Asthma Rep 2018 Jun 15;18(8):42. doi: 10.1007/s11882-018-0796-4. PMID: 29904888

Recent systematic reviews

Effects of motor-cognitive training on dual-task performance in people with Parkinson's disease: a systematic review and meta-analysis.
Johansson H, Folkerts AK, Hammarström I, Kalbe E, Leavy B
J Neurol 2023 Jun;270(6):2890-2907. Epub 2023 Feb 23 doi: 10.1007/s00415-023-11610-8. PMID: 36820916Free PMC Article
Quality of life in Parkinson's disease: A systematic review and meta-analysis of comparative studies.
Zhao N, Yang Y, Zhang L, Zhang Q, Balbuena L, Ungvari GS, Zang YF, Xiang YT
CNS Neurosci Ther 2021 Mar;27(3):270-279. Epub 2020 Dec 28 doi: 10.1111/cns.13549. PMID: 33372386Free PMC Article
Environmental risk factors and Parkinson's disease: An umbrella review of meta-analyses.
Bellou V, Belbasis L, Tzoulaki I, Evangelou E, Ioannidis JP
Parkinsonism Relat Disord 2016 Feb;23:1-9. Epub 2015 Dec 17 doi: 10.1016/j.parkreldis.2015.12.008. PMID: 26739246
The prevalence of Parkinson's disease: a systematic review and meta-analysis.
Pringsheim T, Jette N, Frolkis A, Steeves TD
Mov Disord 2014 Nov;29(13):1583-90. Epub 2014 Jun 28 doi: 10.1002/mds.25945. PMID: 24976103
Parkinson disease subtypes.
Thenganatt MA, Jankovic J
JAMA Neurol 2014 Apr;71(4):499-504. doi: 10.1001/jamaneurol.2013.6233. PMID: 24514863

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...