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Laudanum

MedGen UID:
149002
Concept ID:
C0724655
Organic Chemical; Pharmacologic Substance
Synonyms: Deodorized Tincture of Opium; DTO; Opium tincture; Opium Tincture; Tincture of opium
SNOMED CT: Opium tincture (37451001); Tincture of opium (37451001); Laudanum (37451001)
 

Definition

Also known as Laudanum and formulated for oral administration, Opium tincture is made of air-dried poppy (Papaver somniferum) latex and contains alkaloids such as morphine and codeine. As an antidiarrheal agent, it slows transit of intestinal contents by increasing intestinal smooth muscle tone and inhibiting motility; water is absorbed from fecal contents, decreasing diarrhea. (NCI04) [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLaudanum
  • Laudanum
    • Laudanum
      • Laudanum
        • Laudanum
          • Laudanum
            • Laudanum
              • Laudanum

Recent clinical studies

Etiology

Auriacombe M, Grabot D, Daulouède JP, Vergnolle JP, O'Brien C, Tignol J
J Subst Abuse Treat 1994 Nov-Dec;11(6):565-8. PMID: 7884840

Diagnosis

Van Hout MC, Hearne E
Subst Use Misuse 2015 Apr;50(5):598-608. Epub 2014 Dec 29 doi: 10.3109/10826084.2014.991408. PMID: 25545140
Ellis H
J Perioper Pract 2012 Mar;22(3):103-4. doi: 10.1177/175045891202200306. PMID: 22493878

Therapy

Smale R
J Psychiatr Ment Health Nurs 2001 Oct;8(5):459-63. PMID: 11882167
Auriacombe M, Grabot D, Daulouède JP, Vergnolle JP, O'Brien C, Tignol J
J Subst Abuse Treat 1994 Nov-Dec;11(6):565-8. PMID: 7884840

Prognosis

Ellis H
J Perioper Pract 2012 Mar;22(3):103-4. doi: 10.1177/175045891202200306. PMID: 22493878
Santoro D, Bellinghieri G, Savica V
J Nephrol 2011 May-Jun;24 Suppl 17:S133-6. doi: 10.5301/JN.2011.6481. PMID: 21614795
Auriacombe M, Grabot D, Daulouède JP, Vergnolle JP, O'Brien C, Tignol J
J Subst Abuse Treat 1994 Nov-Dec;11(6):565-8. PMID: 7884840

Clinical prediction guides

Auriacombe M, Grabot D, Daulouède JP, Vergnolle JP, O'Brien C, Tignol J
J Subst Abuse Treat 1994 Nov-Dec;11(6):565-8. PMID: 7884840

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