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Degenerative disease of the central nervous system

MedGen UID:
124363
Concept ID:
C0270715
Disease or Syndrome
Synonyms: Degenerative Diseases, Central Nervous System
SNOMED CT: Degenerative disease of the central nervous system (80690008)
 

Definition

A disorder of the central nervous system characterized by gradual and progressive loss of neural tissue and neurologic function. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDegenerative disease of the central nervous system

Recent clinical studies

Etiology

Zhang H, Bai L, He J, Zhong L, Duan X, Ouyang L, Zhu Y, Wang T, Zhang Y, Shi J
Eur J Med Chem 2017 Dec 1;141:257-272. Epub 2017 Sep 30 doi: 10.1016/j.ejmech.2017.09.068. PMID: 29031072
Briken S, Rosenkranz SC, Keminer O, Patra S, Ketels G, Heesen C, Hellweg R, Pless O, Schulz KH, Gold SM
J Neuroimmunol 2016 Oct 15;299:53-58. Epub 2016 Aug 5 doi: 10.1016/j.jneuroim.2016.08.007. PMID: 27725121
McGinnis E, Andrea Nelson E, Gorecki C, Nixon J
J Tissue Viability 2015 Aug;24(3):83-90. Epub 2015 Jun 4 doi: 10.1016/j.jtv.2015.05.003. PMID: 26100054
Yadav SK, Mindur JE, Ito K, Dhib-Jalbut S
Curr Opin Neurol 2015 Jun;28(3):206-19. doi: 10.1097/WCO.0000000000000205. PMID: 25887768
GAJDUSEK DC, ZIGAS V
Am J Med 1959 Mar;26(3):442-69. PMID: 13626997

Diagnosis

Wood J, Wallin M, Finkelstein J
Stud Health Technol Inform 2013;190:30-2. PMID: 23823365
Koeva V, Bar-Or A, Gendron D, Backman SB
Can J Anaesth 2013 May;60(5):479-83. Epub 2013 Mar 2 doi: 10.1007/s12630-013-9904-z. PMID: 23456228
Schmierer K, Parkes HG, So PW, An SF, Brandner S, Ordidge RJ, Yousry TA, Miller DH
Brain 2010 Mar;133(Pt 3):858-67. Epub 2010 Jan 31 doi: 10.1093/brain/awp335. PMID: 20123726
Wilson J
Arch Dis Child 1972 Apr;47(252):163-70. PMID: 4554083Free PMC Article
Freeman JM, McKhann GM
Adv Pediatr 1969;16:121-75. PMID: 4242467

Therapy

Briken S, Rosenkranz SC, Keminer O, Patra S, Ketels G, Heesen C, Hellweg R, Pless O, Schulz KH, Gold SM
J Neuroimmunol 2016 Oct 15;299:53-58. Epub 2016 Aug 5 doi: 10.1016/j.jneuroim.2016.08.007. PMID: 27725121
Zhang H, Tong R, Bai L, Shi J, Ouyang L
Bioorg Med Chem 2016 Apr 1;24(7):1419-30. Epub 2016 Feb 24 doi: 10.1016/j.bmc.2016.02.030. PMID: 26935940
Kułakowska A, Drozdowski W
Neurol Neurochir Pol 2014;48(6):436-41. Epub 2014 Oct 23 doi: 10.1016/j.pjnns.2014.10.003. PMID: 25482255
Koeva V, Bar-Or A, Gendron D, Backman SB
Can J Anaesth 2013 May;60(5):479-83. Epub 2013 Mar 2 doi: 10.1007/s12630-013-9904-z. PMID: 23456228
Boppana S, Huang H, Ito K, Dhib-Jalbut S
Mt Sinai J Med 2011 Mar-Apr;78(2):207-20. doi: 10.1002/msj.20249. PMID: 21425265

Prognosis

Briken S, Rosenkranz SC, Keminer O, Patra S, Ketels G, Heesen C, Hellweg R, Pless O, Schulz KH, Gold SM
J Neuroimmunol 2016 Oct 15;299:53-58. Epub 2016 Aug 5 doi: 10.1016/j.jneuroim.2016.08.007. PMID: 27725121
Kułakowska A, Drozdowski W
Neurol Neurochir Pol 2014;48(6):436-41. Epub 2014 Oct 23 doi: 10.1016/j.pjnns.2014.10.003. PMID: 25482255
D'hooghe MB, D'Hooghe T, De Keyser J
Gynecol Obstet Invest 2013;75(2):73-84. Epub 2013 Jan 18 doi: 10.1159/000346319. PMID: 23343711
Bertrand E, Schlatter J
Pharmazie 2011 Jan;66(1):75-9. PMID: 21391439
Schmierer K, Parkes HG, So PW, An SF, Brandner S, Ordidge RJ, Yousry TA, Miller DH
Brain 2010 Mar;133(Pt 3):858-67. Epub 2010 Jan 31 doi: 10.1093/brain/awp335. PMID: 20123726

Clinical prediction guides

D'hooghe MB, D'Hooghe T, De Keyser J
Gynecol Obstet Invest 2013;75(2):73-84. Epub 2013 Jan 18 doi: 10.1159/000346319. PMID: 23343711
Schmierer K, Parkes HG, So PW, An SF, Brandner S, Ordidge RJ, Yousry TA, Miller DH
Brain 2010 Mar;133(Pt 3):858-67. Epub 2010 Jan 31 doi: 10.1093/brain/awp335. PMID: 20123726
Bergendal G, Fredrikson S, Almkvist O
Eur Neurol 2007;57(4):193-202. Epub 2007 Jan 1 doi: 10.1159/000099158. PMID: 17272938
Hara S, Kimura H, Hoshino Y, Hayashi N, Negoro T, Okumura A, Kajita Y, Sakuma T, Nakayama T, Hosoya M, Tomoda A, Morisima T
Brain Dev 2003 Aug;25(5):367-9. PMID: 12850518
Riccio M, Di Giaimo R, Pianetti S, Palmieri PP, Melli M, Santi S
Exp Cell Res 2001 Jan 15;262(2):84-94. doi: 10.1006/excr.2000.5085. PMID: 11139332

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