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Cerebral neuroblastoma

MedGen UID:
107851
•Concept ID:
C0559458
•
Neoplastic Process
Synonyms: Central Nervous System Neuroblastoma; central nervous system neuroblastoma; Cerebral Hemispheric Neuroblastoma; cerebral hemispheric neuroblastoma; Cerebral Neuroblastoma; cerebral neuroblastoma; Cerebral Neuroblastoma, PNET; cerebral neuroblastoma, PNET; Neuroblastoma of brain; neuroblastoma of brain; Neuroblastoma of Cerebral Hemispheres; neuroblastoma of cerebral hemispheres; Neuroblastoma of Cerebrum; neuroblastoma of cerebrum; neuroblastoma of telencephalon; neuroblastoma of the cerebral hemisphere; Neuroblastoma of the Cerebral Hemispheres; neuroblastoma of the cerebral hemispheres; Neuroblastoma of the Cerebrum; neuroblastoma of the cerebrum; telencephalon neuroblastoma
SNOMED CT: Neuroblastoma of brain (281560004)
 
Monarch Initiative: MONDO:0002900

Definition

A neuroblastoma arising from the central nervous system. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCerebral neuroblastoma

Professional guidelines

PubMed

Preirradiation cisplatin and etoposide in the treatment of high-risk medulloblastoma and other malignant embryonal tumors of the central nervous system: a phase II study.
Kovnar EH, Kellie SJ, Horowitz ME, Sanford RA, Langston JW, Mulhern RK, Jenkins JJ, Douglass EC, Etcubanas EE, Fairclough DL
J Clin Oncol 1990 Feb;8(2):330-6. doi: 10.1200/JCO.1990.8.2.330. PMID: 2153766
Primary cerebral neuroblastoma. Long-term follow-up review and therapeutic guidelines.
Berger MS, Edwards MS, Wara WM, Levin VA, Wilson CB
J Neurosurg 1983 Sep;59(3):418-23. doi: 10.3171/jns.1983.59.3.0418. PMID: 6886755

Recent clinical studies

Etiology

Primary cerebral neuroblastoma: a case report and review.
Etuş V, Kurtkaya O, Sav A, Ilbay K, Ceylan S
Tohoku J Exp Med 2002 May;197(1):55-65. doi: 10.1620/tjem.197.55. PMID: 12180794
Intraventricular cerebral neuroblastoma. Analysis of subtypes and comparison with hemispheric neuroblastoma.
Rhodes RH, Cole M, Takaoka Y, Roessmann U, Cotes EE, Simon J
Arch Pathol Lab Med 1994 Sep;118(9):897-911. PMID: 8080360
Neuroblastoma and diagnostic imaging.
Sherazi ZA, Abdullah AW, Malik AS, Saad R
Ann Acad Med Singap 1993 Sep;22(5):701-6. PMID: 8267349
Preirradiation cisplatin and etoposide in the treatment of high-risk medulloblastoma and other malignant embryonal tumors of the central nervous system: a phase II study.
Kovnar EH, Kellie SJ, Horowitz ME, Sanford RA, Langston JW, Mulhern RK, Jenkins JJ, Douglass EC, Etcubanas EE, Fairclough DL
J Clin Oncol 1990 Feb;8(2):330-6. doi: 10.1200/JCO.1990.8.2.330. PMID: 2153766
Primary cerebral neuroblastoma. Long-term follow-up review and therapeutic guidelines.
Berger MS, Edwards MS, Wara WM, Levin VA, Wilson CB
J Neurosurg 1983 Sep;59(3):418-23. doi: 10.3171/jns.1983.59.3.0418. PMID: 6886755

Diagnosis

Glioneuronal tumors of the central nervous system.
McLendon RE, Provenzale J
Brain Tumor Pathol 2002;19(2):51-8. doi: 10.1007/BF02478927. PMID: 12622133
Primary cerebral neuroblastoma: a case report and review.
Etuş V, Kurtkaya O, Sav A, Ilbay K, Ceylan S
Tohoku J Exp Med 2002 May;197(1):55-65. doi: 10.1620/tjem.197.55. PMID: 12180794
Cavernous sinus neuroblastoma.
Kratimenos GP, Crockard HA
Br J Neurosurg 1993;7(6):691-6. doi: 10.3109/02688699308995101. PMID: 8161434
Preirradiation cisplatin and etoposide in the treatment of high-risk medulloblastoma and other malignant embryonal tumors of the central nervous system: a phase II study.
Kovnar EH, Kellie SJ, Horowitz ME, Sanford RA, Langston JW, Mulhern RK, Jenkins JJ, Douglass EC, Etcubanas EE, Fairclough DL
J Clin Oncol 1990 Feb;8(2):330-6. doi: 10.1200/JCO.1990.8.2.330. PMID: 2153766
Primary cerebral neuroectodermal tumors: neuroblastoma, differentiated neuroblastoma, and composite neuroectodermal tumor.
Dehner LP, Abenoza P, Sibley RK
Ultrastruct Pathol 1988 Sep-Oct;12(5):479-94. doi: 10.3109/01913128809032233. PMID: 3194993

Therapy

Concurrent Chemoradiotherapy as an Adjuvant Treatment of Primary Central Nervous System Neuroblastoma.
Amor RB, Bohli M, Naimi Z, Yahyaoui J, Kochbati L
Perm J 2022 Jun 29;26(2):166-171. Epub 2022 Jun 17 doi: 10.7812/TPP/21.147. PMID: 35933664Free PMC Article
High-dose chemotherapy with autologous stem cell transplantation in adults with recurrent embryonal tumors of the central nervous system.
Gill P, Litzow M, Buckner J, Arndt C, Moynihan T, Christianson T, Ansell S, Galanis E
Cancer 2008 Apr 15;112(8):1805-11. doi: 10.1002/cncr.23362. PMID: 18300237
Effective chemotherapy for advanced CNS embryonal tumors in adults.
Galanis E, Buckner JC, Schomberg PJ, Hammack JE, Raffel C, Scheithauer BW
J Clin Oncol 1997 Aug;15(8):2939-44. doi: 10.1200/JCO.1997.15.8.2939. PMID: 9256138
Preirradiation cisplatin and etoposide in the treatment of high-risk medulloblastoma and other malignant embryonal tumors of the central nervous system: a phase II study.
Kovnar EH, Kellie SJ, Horowitz ME, Sanford RA, Langston JW, Mulhern RK, Jenkins JJ, Douglass EC, Etcubanas EE, Fairclough DL
J Clin Oncol 1990 Feb;8(2):330-6. doi: 10.1200/JCO.1990.8.2.330. PMID: 2153766

Prognosis

Primary cerebral neuroblastoma: a case report and review.
Etuş V, Kurtkaya O, Sav A, Ilbay K, Ceylan S
Tohoku J Exp Med 2002 May;197(1):55-65. doi: 10.1620/tjem.197.55. PMID: 12180794
Intraventricular cerebral neuroblastoma. Analysis of subtypes and comparison with hemispheric neuroblastoma.
Rhodes RH, Cole M, Takaoka Y, Roessmann U, Cotes EE, Simon J
Arch Pathol Lab Med 1994 Sep;118(9):897-911. PMID: 8080360
Preirradiation cisplatin and etoposide in the treatment of high-risk medulloblastoma and other malignant embryonal tumors of the central nervous system: a phase II study.
Kovnar EH, Kellie SJ, Horowitz ME, Sanford RA, Langston JW, Mulhern RK, Jenkins JJ, Douglass EC, Etcubanas EE, Fairclough DL
J Clin Oncol 1990 Feb;8(2):330-6. doi: 10.1200/JCO.1990.8.2.330. PMID: 2153766
Primary cerebral neuroblastoma. Long-term follow-up review and therapeutic guidelines.
Berger MS, Edwards MS, Wara WM, Levin VA, Wilson CB
J Neurosurg 1983 Sep;59(3):418-23. doi: 10.3171/jns.1983.59.3.0418. PMID: 6886755
DOPA metabolism in neuroblastoma.
Helson L, Johnson GA, Smith R
Med Pediatr Oncol 1980;8(4):317-22. doi: 10.1002/mpo.2950080402. PMID: 6779102

Clinical prediction guides

Comparative immunohistochemical study of insulin-like growth factor II and insulin-like growth factor receptor type 1 in pediatric brain tumors.
Ogino S, Kubo S, Abdul-Karim FW, Cohen ML
Pediatr Dev Pathol 2001 Jan-Feb;4(1):23-31. doi: 10.1007/s100240010112. PMID: 11200487
Effective chemotherapy for advanced CNS embryonal tumors in adults.
Galanis E, Buckner JC, Schomberg PJ, Hammack JE, Raffel C, Scheithauer BW
J Clin Oncol 1997 Aug;15(8):2939-44. doi: 10.1200/JCO.1997.15.8.2939. PMID: 9256138
Ultrastructural characterization of oligodendroglial-like cells in central nervous system tumors.
Cenacchi G, Giangaspero F, Cerasoli S, Manetto V, Martinelli GN
Ultrastruct Pathol 1996 Nov-Dec;20(6):537-47. doi: 10.3109/01913129609016358. PMID: 8940761
DOPA metabolism in neuroblastoma.
Helson L, Johnson GA, Smith R
Med Pediatr Oncol 1980;8(4):317-22. doi: 10.1002/mpo.2950080402. PMID: 6779102
Primary cerebral neuroblastoma. A clinicopathological study of 35 cases.
Horten BC, Rubinstein LJ
Brain 1976 Dec;99(4):735-56. doi: 10.1093/brain/99.4.735. PMID: 1030655

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