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Positive CSF toxoplasma gondii nucleic acid test

MedGen UID:
1054896
•Concept ID:
CN377067
•
Finding
Synonym: Positive CSF toxoplasma gondii PCR
 
HPO: HP:0430124

Definition

Detection of Toxoplasma gondii nucleic acid in the cerebrospinal fluid (CSF) by a method such as polymerase chain reaction. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPositive CSF toxoplasma gondii nucleic acid test

Recent clinical studies

Etiology

Polymerase chain reaction in cerebrospinal fluid for the diagnosis of congenital toxoplasmosis.
Olariu TR, Remington JS, Montoya JG
Pediatr Infect Dis J 2014 Jun;33(6):566-70. doi: 10.1097/INF.0000000000000256. PMID: 24445828
Polymerase chain reaction for diagnosis of cerebral toxoplasmosis in cerebrospinal fluid in HIV-positive patients.
Julander I, Martin C, Lappalainen M, Guy E, Isberg B, Evengård B
Scand J Infect Dis 2001;33(7):538-41. doi: 10.1080/00365540110026548. PMID: 11515766
Diagnosis of AIDS-related focal brain lesions: a decision-making analysis based on clinical and neuroradiologic characteristics combined with polymerase chain reaction assays in CSF.
Antinori A, Ammassari A, De Luca A, Cingolani A, Murri R, Scoppettuolo G, Fortini M, Tartaglione T, Larocca LM, Zannoni G, Cattani P, Grillo R, Roselli R, Iacoangeli M, Scerrati M, Ortona L
Neurology 1997 Mar;48(3):687-94. doi: 10.1212/wnl.48.3.687. PMID: 9065549

Diagnosis

Polymerase chain reaction in cerebrospinal fluid for the diagnosis of congenital toxoplasmosis.
Olariu TR, Remington JS, Montoya JG
Pediatr Infect Dis J 2014 Jun;33(6):566-70. doi: 10.1097/INF.0000000000000256. PMID: 24445828
Neurotoxoplasmosis diagnosis for HIV-1 patients by real-time PCR of cerebrospinal fluid.
Nogui FL, Mattas S, Turcato Júnior G, Lewi DS
Braz J Infect Dis 2009 Feb;13(1):18-23. doi: 10.1590/s1413-86702009000100006. PMID: 19578625
Polymerase chain reaction for diagnosis of cerebral toxoplasmosis in cerebrospinal fluid in HIV-positive patients.
Julander I, Martin C, Lappalainen M, Guy E, Isberg B, Evengård B
Scand J Infect Dis 2001;33(7):538-41. doi: 10.1080/00365540110026548. PMID: 11515766
Diagnosis of AIDS-related focal brain lesions: a decision-making analysis based on clinical and neuroradiologic characteristics combined with polymerase chain reaction assays in CSF.
Antinori A, Ammassari A, De Luca A, Cingolani A, Murri R, Scoppettuolo G, Fortini M, Tartaglione T, Larocca LM, Zannoni G, Cattani P, Grillo R, Roselli R, Iacoangeli M, Scerrati M, Ortona L
Neurology 1997 Mar;48(3):687-94. doi: 10.1212/wnl.48.3.687. PMID: 9065549

Prognosis

Neurotoxoplasmosis diagnosis for HIV-1 patients by real-time PCR of cerebrospinal fluid.
Nogui FL, Mattas S, Turcato Júnior G, Lewi DS
Braz J Infect Dis 2009 Feb;13(1):18-23. doi: 10.1590/s1413-86702009000100006. PMID: 19578625
Polymerase chain reaction for diagnosis of cerebral toxoplasmosis in cerebrospinal fluid in HIV-positive patients.
Julander I, Martin C, Lappalainen M, Guy E, Isberg B, Evengård B
Scand J Infect Dis 2001;33(7):538-41. doi: 10.1080/00365540110026548. PMID: 11515766

Clinical prediction guides

Neurotoxoplasmosis diagnosis for HIV-1 patients by real-time PCR of cerebrospinal fluid.
Nogui FL, Mattas S, Turcato Júnior G, Lewi DS
Braz J Infect Dis 2009 Feb;13(1):18-23. doi: 10.1590/s1413-86702009000100006. PMID: 19578625
Diagnosis of AIDS-related focal brain lesions: a decision-making analysis based on clinical and neuroradiologic characteristics combined with polymerase chain reaction assays in CSF.
Antinori A, Ammassari A, De Luca A, Cingolani A, Murri R, Scoppettuolo G, Fortini M, Tartaglione T, Larocca LM, Zannoni G, Cattani P, Grillo R, Roselli R, Iacoangeli M, Scerrati M, Ortona L
Neurology 1997 Mar;48(3):687-94. doi: 10.1212/wnl.48.3.687. PMID: 9065549

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