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2014 5
2015 5
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33 results

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Jacob-induced transcriptional inactivation of CREB promotes Aβ-induced synapse loss in Alzheimer's disease.
Grochowska KM, Gomes GM, Raman R, Kaushik R, Sosulina L, Kaneko H, Oelschlegel AM, Yuanxiang P, Reyes-Resina I, Bayraktar G, Samer S, Spilker C, Woo MS, Morawski M, Goldschmidt J, Friese MA, Rossner S, Navarro G, Remy S, Reissner C, Karpova A, Kreutz MR. Grochowska KM, et al. EMBO J. 2023 Feb 15;42(4):e112453. doi: 10.15252/embj.2022112453. Epub 2023 Jan 3. EMBO J. 2023. PMID: 36594364 Free PMC article.
Abeta-regulated trafficking of Jacob induces transcriptional inactivation of CREB leading to impairment and loss of synapses in mouse models of AD. The small chemical compound Nitarsone selectively hinders the assembly of a Jacob/LIM-only 4 (LMO4)/ Protein phosphatase 1 (P …
Abeta-regulated trafficking of Jacob induces transcriptional inactivation of CREB leading to impairment and loss of synapses in mouse models …
Histomonosis in Poultry: A Comprehensive Review.
Beer LC, Petrone-Garcia VM, Graham BD, Hargis BM, Tellez-Isaias G, Vuong CN. Beer LC, et al. Front Vet Sci. 2022 May 6;9:880738. doi: 10.3389/fvets.2022.880738. eCollection 2022. Front Vet Sci. 2022. PMID: 35601402 Free PMC article. Review.
Treating and preventing H. meleagridis infection have become more difficult since 2015, when nitarsone was voluntarily removed from the market, leaving the poultry industry with no approved prophylactics, therapeutics, or vaccines to combat histomonosis. ...
Treating and preventing H. meleagridis infection have become more difficult since 2015, when nitarsone was voluntarily removed from t …
Organoarsenicals in poultry litter: detection, fate, and toxicity.
P Mangalgiri K, Adak A, Blaney L. P Mangalgiri K, et al. Environ Int. 2015 Feb;75:68-80. doi: 10.1016/j.envint.2014.10.022. Epub 2014 Nov 15. Environ Int. 2015. PMID: 25461415 Review.
Four organoarsenicals are commonly employed as feed additives: arsanilic acid, carbarsone, nitarsone, and roxarsone. Organoarsenicals are composed of a phenylarsonic acid molecule with substituted functional groups. ...In reviewing the literature on organoarsenicals, sever …
Four organoarsenicals are commonly employed as feed additives: arsanilic acid, carbarsone, nitarsone, and roxarsone. Organoarsenicals …
Role of ArsEFG in Roxarsone and Nitarsone Detoxification and Resistance.
Chen J, Zhang J, Rosen BP. Chen J, et al. Environ Sci Technol. 2019 Jun 4;53(11):6182-6191. doi: 10.1021/acs.est.9b01187. Epub 2019 May 14. Environ Sci Technol. 2019. PMID: 31059239
Roxarsone (3-nitro-4-hydroxybenzenearsenate or Rox(V)) and nitarsone (4-nitrobenzene arsenate or Nit(V)) are synthetic aromatic organoarsenicals used in the poultry industry as additives to prevent coccidiosis and improve feed efficiency. ...Identification of the coupled p …
Roxarsone (3-nitro-4-hydroxybenzenearsenate or Rox(V)) and nitarsone (4-nitrobenzene arsenate or Nit(V)) are synthetic aromatic organ …
Poultry Consumption and Arsenic Exposure in the U.S. Population.
Nigra AE, Nachman KE, Love DC, Grau-Perez M, Navas-Acien A. Nigra AE, et al. Environ Health Perspect. 2017 Mar;125(3):370-377. doi: 10.1289/EHP351. Epub 2016 Oct 13. Environ Health Perspect. 2017. PMID: 27735790 Free PMC article.
BACKGROUND: Arsenicals (roxarsone and nitarsone) used in poultry production likely increase inorganic arsenic (iAs), monomethylarsonic acid (MMA), dimethylarsinic acid (DMA), and roxarsone or nitarsone concentrations in poultry meat. ...We hypothesized first, that p …
BACKGROUND: Arsenicals (roxarsone and nitarsone) used in poultry production likely increase inorganic arsenic (iAs), monomethylarsoni …
Critical Review: Future Control of Blackhead Disease (Histomoniasis) in Poultry.
Clark S, Kimminau E. Clark S, et al. Avian Dis. 2017 Sep;61(3):281-288. doi: 10.1637/11593-012517-ReviewR. Avian Dis. 2017. PMID: 28957000 Review.
The mini-symposium included university researchers and industry veterinarians discussing blackhead in the United States and Europe including insights on the disease pathogenesis and epidemiology, as well as an update on the current state of blackhead in the United States since th …
The mini-symposium included university researchers and industry veterinarians discussing blackhead in the United States and Europe including …
Environmental concerns of roxarsone in broiler poultry feed and litter in Maryland, USA.
Fisher DJ, Yonkos LT, Staver KW. Fisher DJ, et al. Environ Sci Technol. 2015 Feb 17;49(4):1999-2012. doi: 10.1021/es504520w. Epub 2015 Feb 4. Environ Sci Technol. 2015. PMID: 25608233 Review.
In 2012, Maryland passed a law banning the use of arsenic additives except nitarsone in poultry feed. In 2013, the USFDA withdrew approval of roxarsone, carbarsone, and arsanilic but is reviewing nitarsone....
In 2012, Maryland passed a law banning the use of arsenic additives except nitarsone in poultry feed. In 2013, the USFDA withdrew app …
Retrospective Study of Histomoniasis (Blackhead) in California Turkey Flocks, 2000-2014.
Hauck R, Stoute S, Chin RP, Sentíes-Cué CG, Shivaprasad HL. Hauck R, et al. Avian Dis. 2018 Mar;62(1):94-100. doi: 10.1637/11772-112017-Reg.1. Avian Dis. 2018. PMID: 29620457
The flagellate parasite Histomonas meleagridis causes a severe disease in turkeys. Since nitarsone, the last antiflagellate feed additive, was withdrawn from the market, H. meleagridis has gained increasing clinical and economic importance, and frequently entire turkey flo …
The flagellate parasite Histomonas meleagridis causes a severe disease in turkeys. Since nitarsone, the last antiflagellate feed addi …
Nitarsone, Inorganic Arsenic, and Other Arsenic Species in Turkey Meat: Exposure and Risk Assessment Based on a 2014 U.S. Market Basket Sample.
Nachman KE, Love DC, Baron PA, Nigra AE, Murko M, Raber G, Francesconi KA, Navas-Acien A. Nachman KE, et al. Environ Health Perspect. 2017 Mar;125(3):363-369. doi: 10.1289/EHP225. Epub 2016 Oct 13. Environ Health Perspect. 2017. PMID: 27735789 Free PMC article.
Nitarsone was withdrawn from the U.S. market in 2015, but its use in other countries may continue. OBJECTIVES: We characterized the impact of nitarsone use on arsenic species in turkey meat and arsenic exposures among turkey consumers, and we estimated cancer risk i …
Nitarsone was withdrawn from the U.S. market in 2015, but its use in other countries may continue. OBJECTIVES: We characterized the i …
Blackhead disease: reduced sensitivity of Histomonas meleagridis to nitarsone in vitro and in vivo.
Abraham M, McDougald LR, Beckstead RB. Abraham M, et al. Avian Dis. 2014 Mar;58(1):60-3. doi: 10.1637/10635-080913-Reg.1. Avian Dis. 2014. PMID: 24758114
However, there was no inhibition of growth in strain MNC treated with nitarsone at 100 ppm, while reduced growth was seen at 400 ppm. To test the resistance of strain MNC to nitarsone in vivo, turkey poults fed a nitarsone or a control diet were inoculated cl …
However, there was no inhibition of growth in strain MNC treated with nitarsone at 100 ppm, while reduced growth was seen at 400 ppm. …
33 results