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Intradermal study of a new local anaesthetic agent aptocaine.
Reynolds F, Bryson TH, Nicholas AD. Reynolds F, et al. Br J Anaesth. 1976 Apr;48(4):347-54. doi: 10.1093/bja/48.4.347. Br J Anaesth. 1976. PMID: 776194 Free article. Clinical Trial.
In a second trial in 27 subjects, 1% aptocaine was compared with mepivacaine and prilocaine, both 1, 2 and 3%. ...Aptocaine had marked vasoconstrictor activity, which was maximal at 1%. ...
In a second trial in 27 subjects, 1% aptocaine was compared with mepivacaine and prilocaine, both 1, 2 and 3%. ...Aptocaine ha …
Studies on inhibition of TSH stimulation of adenyl cyclase activity in thyroid plasma membrane preparations by propranolol.
Marshall NJ, Von Borcke S, Malan PG. Marshall NJ, et al. Endocrinology. 1975 Jun;96(6):1513-9. doi: 10.1210/endo-96-6-1513. Endocrinology. 1975. PMID: 165065
Since (i) and inhibition was observed at concentrations of propranolol between 10-minus 4 and 10- minus 3M, and appeared to be noncompetitive (ii) the optical isomers of propranolol were equipotent, (iii) inhibition was specific for propranolol since it was not observed with the …
Since (i) and inhibition was observed at concentrations of propranolol between 10-minus 4 and 10- minus 3M, and appeared to be noncompetitiv …