DNA or RNA oligonucleotide 2'-hydrazides for chemoselective click-type ligation with carbonyl compounds.
Khomyakova EA, Zubin EM, Smirnov IP, Pozmogova GE, Stetsenko DA, Oretskaya TS.
Khomyakova EA, et al.
Nucleosides Nucleotides Nucleic Acids. 2011 Jul-Aug;30(7-8):577-84. doi: 10.1080/15257770.2011.586010.
Nucleosides Nucleotides Nucleic Acids. 2011.
PMID: 21888548
Fully deprotected oligonucleotides containing a hydrazide group at the 2'-position of a uridine residue were obtained by a novel two-step procedure: periodate cleavage of an oligonucleotide with 1,2-diol group followed by conversion of the aldehyde to hydrazide with an extended l …
Fully deprotected oligonucleotides containing a hydrazide group at the 2'-position of a uridine residue were obtained by a novel two-step pr …